Elevated cortisol levels in Cushing's disease are associated with cognitive decrements

Psychosomatic Medicine

Volumn 63, Issue 6, 2001, Pages 985-993

  Starkman, Monica N ^a,b   Giordani, Bruno ^a   Berent, Stanley ^a   Schork, M Anthony ^b   Schteingart, David E ^c  

^a UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

^c UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

Cognition; Cortisol; Cushing's disease; Learning; Neuropsychological tests

Indexed keywords

HYDROCORTISONE;

ADULT; ARTICLE; COGNITION; COGNITIVE DEFECT; CONTROLLED STUDY; CUSHING SYNDROME; DEPRESSION; DEPTH PERCEPTION; FEMALE; HIPPOCAMPUS; HUMAN; HYDROCORTISONE BLOOD LEVEL; INTELLIGENCE QUOTIENT; LEARNING; MAJOR CLINICAL STUDY; MALE; NEOCORTEX; PRIORITY JOURNAL; RECALL; SCORING SYSTEM; STATISTICAL ANALYSIS; STRESS; VERBAL BEHAVIOR;

EID: 0035180886     PISSN: 00333174     EISSN: None     Source Type: Journal    
DOI: 10.1097/00006842-200111000-00018     Document Type: Article

References (50)

1. Adrenalectomy-induced granule cell degeneration in the rat hippocampal dentate gyrus: Characterization of an in vivo model of controlled neuronal death
2. Long-term adrenalectomy causes loss of dentate gyrus and pyramidal neurons in the adult hippocampus
3. Stress induces atrophy of apical dendrites of hippocampus CA3 pyramidal neurons
4. Hippocampal damage associated with prolonged and fatal stress in primates
5. Hippocampal damage associated with prolonged glucocorticoid exposure in primates
6. Repeated stress causes reversible impairments of spatial memory performance
7. Depressed mood and other psychiatric manifestations of Cushing's syndrome: Relationship of hormone levels
8. EEG changes and serum cortisol levels in Cushing's syndrome
9. Hippocampal formation volume, memory dysfunction, and cortisol levels in patients with Cushing's syndrome
10. Correlation of bedside cognitive and neuropsychological tests in patients with Cushing's syndrome
11. Neuropsychological deficits in Cushing's syndrome
12. Cognitive decline in patients with Cushing's syndrome
13. Memory impairment in Cushing's disease
14. Cushing's syndrome: A psychiatric study of 29 patients
15. A multiple scoring method for the assessment of complex memory functions
16. Wechsler Adult Intelligence Scale: Cortical performance localization by fluorodeoxyglucose F 18-positron emission tomography
17. Neuropsychological correlates of rapidly vs. slowly growing intrinsic cerebral neoplasms
18. Constructional apraxia in patients with discrete missile wounds of the brain
19. Memory and the hippocampus
20. The primate hippocampal formation: Evidence for a time-limited role in memory storage
21. Specificity in the correlation of verbal memory and hippocampal neuron loss: Dissociation of memory, language, and verbal intellectual ability
22. Dissociating prefrontal and hippocampal function in episodic memory encoding
23. Memory and the hippocampus: A synthesis of findings with rats, monkeys, and humans
24. The hippocampal system and declarative memory in animals
25. Development of a rating scale for primary depressive illness
26. Neuropsychiatric manifestations of patients with Cushing's syndrome
27. Spatial disorientation in Alzheimer's disease
28. 'Subcortical dementia': The neuropsychological evidence
29. Adult age differences in spatial memory: Effects of structural context and practice
30. Visuoperceptual performances in aging and dementia: Clinical and theoretical implications
31. Spatial abilities and deficits in aging and age-related disorders
32. MRI-based measurement of hippocampal volume in patients with combat-related posttraumatic stress disorder
33. Accelerated forgetting in Alzheimer-type dementia
34. Memory testing to improve the differential diagnosis of Alzheimer's disease
35. Semantic (verbal) and figural memory impairment in alcoholics
36. Neuropsychological deficits in psychotic versus nonpsychotic major depression and no mental illness
37. Long-term spatial memory in rats with hippocampal lesions
38. Cortisol secretion and Alzheimer's disease progression: A preliminary report
39. Cortisol levels during human aging predict hippocampal atrophy and memory deficits
40. Decreased memory performance in healthy humans induced by stress-level cortisol treatment
41. Anatomical resolution of two types of corticosterone receptor sites in rat brain with in vitro autoradiography and computerized image analysis
42. Two receptor systems for corticosterone in rat brain: Microdistribution and differential occupation
43. Glucocorticoids, stress and exacerbation of excitotoxic neuron death
44. Glucocorticoid endangerment of hippocampal neurons is NMDA-receptor dependent
45. Glucocorticoids and hippocampal atrophy in neuropsychiatric disorders
46. Decrease in cortisol reverses human hippocampal atrophy following treatment of Cushing's disease