Involvement of prostaglandin receptors (EPR2-4) in in vivo immunosuppression of PGE2 in rat skin transplant model

International Immunopharmacology

Volumn 5, Issue 7-8, 2005, Pages 1131-1139

  Fujimoto, Yoshimi ^a   Iwagaki, Hiromi ^a   Ozaki, Michitaka ^b   Ogino, Tetsuya ^a   Murata, Hiroshi ^a   Dong, Sheng Sun ^b   Sadamori, Hiroshi ^a   Hideo, Kohka Takahashi ^a   Tanaka, Noriaki ^a   Yagi, Takahito ^a  

^a OKAYAMA UNIVERSITY   (Japan)

^b HOKKAIDO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

EP receptor agonists; Immunosuppression; Prostaglandin E2; Skin transplantation

Indexed keywords

CYTOKINE; GAMMA INTERFERON; IMMUNOSUPPRESSIVE AGENT; INTERLEUKIN 10; ONO AE 248; ONO AE1 239; ONO AE1 259 01; ONO AE1 329; PROSTAGLANDIN E RECEPTOR; PROSTAGLANDIN E1; PROSTAGLANDIN E2; UNCLASSIFIED DRUG;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; DOWN REGULATION; GRAFT REJECTION; GRAFT SURVIVAL; HISTOCOMPATIBILITY; HISTOLOGY; IMMUNOSUPPRESSIVE TREATMENT; MIXED LYMPHOCYTE REACTION; NONHUMAN; ORGAN DONOR; PRIORITY JOURNAL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SKIN ALLOGRAFT; SKIN TRANSPLANTATION; SPLEEN CELL; UPREGULATION;

ANIMALS; DINOPROSTONE; FEMALE; GRAFT SURVIVAL; IMMUNOSUPPRESSIVE AGENTS; INTERFERON TYPE II; LYMPHOCYTE CULTURE TEST, MIXED; MALE; RATS; RATS, INBRED ACI; RATS, INBRED LEW; RECEPTORS, PROSTAGLANDIN E; RNA, MESSENGER; SKIN TRANSPLANTATION;

EID: 21144456524     PISSN: 15675769     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.intimp.2005.01.014     Document Type: Article

References (29)

1. T.C. van der Pouw Kraan, L.C. Boeije, R.J. Smeenk, J. Wijdenes, and L.A. Aarden Prostaglandin-E2 is a potent inhibitor of human interleukin 12 production J Exp Med 181 2 1995 775 779
2. N.R. Ferreri, T. Sarr, P.W. Askenase, and N.H. Ruddle Molecular regulation of tumor necrosis factor-alpha and lymphotoxin production in T cells: inhibition by prostaglandin E2 J Biol Chem 267 13 1992 9443 9449
3. R.A. Coleman, W.L. Smith, and S. Narumiya International union of pharmacology classification of prostanoid receptors: properties, distribution and structure of the receptors and their subtypes Pharmacol Rev 46 2 1994 205 229
4. L. Bastien, N. Sawyer, R. Grygorczyk, K.M. Metters, and M. Adam Cloning, functional expression, and characterization of the human prostaglandin E2 receptor EP2 subtype J Biol Chem 269 16 1994 11873 11877
5. H.K. Takahashi, H. Iwagaki, T. Yoshino, S. Mori, and T. Morichika Prostaglandin E2 inhibits IL-18-induced ICAM-1 and B7.2 expression through EP2/EP4 receptors in human peripheral blood mononuclear cells J Immunol 168 9 2002 4446 4454
6. S.N. Zhu, J. Yamada, J.W. Streilein, and M.R. Dana ICAM-1 deficiency suppresses host allosensitization and rejection of MHC-disparate corneal transplants Transplantation 69 5 2000 1008 1013
7. H. Itoh, H.K. Takahashi, H. Iwagaki, T. Yoshino, and Y. Morimoto Effect of histamine on intercellular adhesion molecule-1 (ICAM-1) expression and production of IFN-γ and IL-12 in mixed lymphocyte reaction stimulated with IL-18 Transplantation 74 6 2002 864 870
8. H.K. Takahashi, A. Yoshida, H. Iwagaki, T. Yoshino, and H. Itoh Histamine regulation of interleukin-18-initiating cytokine cascade is associated with down regulation of intercellular adhesion molecule-1 expression in human peripheral blood mononuclear cells J Pharmacol Exp Ther 300 1 2002 227 235
9. D. Tzachanis, A. Berezovskaya, L.M. Nadler, and V.A. Boussiotis Blockade of B7/CD28 in mixed lymphocyte reaction cultures results in the generation of alternatively activated macrophages, which suppress T-cell responses Blood 99 4 2002 1465 1473
10. T. Yagi, H. Iwagaki, N. Urushihara, K. Kobashi, and A. Nakao Participation of IL-18 in human cholestatic cirrhosis and acute rejection: analysis in living donor liver transplantation Transplant Proc 33 1-2 2001 421 425
11. T. Kamei, M.P. Callery, and M.W. Flye Intragraft delivery of 16, 16-dimethyl PGE2 induces donor-specific tolerance in rat cardiac allograft recipients Transplantation 51 1 1991 242 246
12. I.H. Koh, P.C. Kim, S.W. Chung, T. Waddell, and P.Y. Wong The effects of 16, 16 dimethyl prostaglandin E2 therapy alone and in combination with low-dose cyclosporine on rat small intestinal transplantation Transplantation 54 4 1992 592 598
13. T. Morichika, H.K. Takahashi, H. Iwagaki, T. Yagi, and S. Saito Effect of prostaglandin E2 on intercellular adhesion molecule-1 and B7 expression in mixed lymphocyte reaction Transplantation 75 12 2003 2100 2105
14. S. Kubo, H.K. Takahashi, M. Takei, H. Iwagaki, T. Yoshino, and N. Tanaka E-prostanoid (EP)2/EP4 receptor-dependent maturation of human monocyte-derived dendritic cells and induction of helper T2 polarization J Pharmacol Exp Ther 309 2004 (Jun) 1213 1220
15. D.S. Sum, T. Yagi, T. Oyama, H. Matsukawa, H. Matsuda, and H. Sadamori Intraportal donor bone marrow transplantation improves intestinal allograft survival in rats under FK506-based immunosuppression J Int Med Res 31 2003 281 289
16. S. Narumiya, Y. Sugimoto, and F. Ushikubi Prostanoid receptors: structures, properties, and functions Physiol Rev 79 4 1999 1193 1226
17. M. Kiriyama, F. Ushikubi, T. Kobayashi, M. Hirata, Y. Sugimoto, and S. Narumiya Ligand binding specificities of the eight types and subtypes of the mouse prostanoid receptors expressed in Chinese hamster ovary cells Br J Pharmacol 122 2 1997 217 224
18. H. Hizaki, E. Segi, Y. Sugimoto, M. Hirose, and T. Saji Abortive expansion of the cumulus and impaired fertility in mice lacking the prostaglandin E receptor subtype EP(2) Proc Natl Acad Sci U S A 96 18 1999 10501 10506
19. C.R. Kennedy, Y. Zhang, S. Brandon, Y. Guan, and K. Coffee Salt-sensitive hypertension and reduced fertility in mice lacking the prostaglandin EP2 receptor Nat Med 5 2 1999 217 220
20. M. Nguyen, T. Camenisch, J.N. Snouwaert, E. Hicks, and T.M. Coffman The prostaglandin receptor EP4 triggers remodelling of the cardiovascular system at birth Nature 390 6655 1997 78 81
21. C. Nataraj, D.W. Thomas, S.L. Tilley, M.T. Nguyen, and R. Mannon Receptors for prostaglandin E2 that regulate cellular immune responses in the mouse J Clin Invest 108 8 2001 1229 1235
22. Y. Boie, R. Stocco, N. Sawyer, D.M. Slipetz, and M.D. Ungrin Molecular cloning and characterization of the four rat prostaglandin E2 prostanoid receptor subtypes Eur J Pharmacol 340 2-3 1997 227 241
23. S.G. Harris, J. Padilla, L. Koumas, D. Ray, and R.P. Phipps Prostaglandins as modulators of immunity Trends Immunol 23 3 2002 144 150
24. H. Harizi, M. Juzan, C. Grosset, M. Rashedi, and N. Gualde Dendritic cells issued in vitro from bone marrow produce PGE2 that contributes to the immunomodulation induced by antigen-presenting cells Cell Immunol 209 1 2001 19 28
25. N. Hatae, Y. Sugimoto, and A. Ichikawa Prostaglandin receptors: advances in the study of EP3 receptor signaling J Biochem 131 6 2002 781 784
26. N. Hatae, K. Yamaoka, Y. Sugimoto, M. Negishi, and A. Ichikawa Augmentation of receptor-mediated adenylyl cyclase activity by Gi-coupled prostaglandin receptor subtype EP3 in a Gβγ subunit-independent manner Biochem Biophys Res Commun 290 1 2002 162 168
27. C.M. Hilkens, A. Snijders, F.G. Snijdewint, E.A. Wierenga, and M.L. Kapsenberg Modulation of T-cell cytokine secretion by accessory cell-derived products Eur Respir J, Suppl 22 1996 90s 94s
28. D. Bloom, N. Jabrane-Ferrat, L. Zeng, A. Wu, and L. Li Prostaglandin E2 enhancement of interferon-gamma production by antigen-stimulated type 1 helper T cells Cell Immunol 194 1 1999 21 27
29. P. Kalinski, C.M. Hilkens, A. Snijders, F.G. Snijdewint, and M.L. Kapsenberg Dendritic cells, obtained from peripheral blood precursors in the presence of PGE2, promote Th2 responses Adv Exp Med Biol 417 1997 363 367