Dendritic cells, obtained from peripheral blood precursors in the presence of PGE2, promote Th2 responses

Advances in Experimental Medicine and Biology

Volumn 417, Issue , 1997, Pages 363-367

  Kaliński, Paweł ^a   Hilkens, Catharien M U ^a   Snijders, Alies ^a   Snijdewint, Frank G M ^a   Kapsenberg, Martien L ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 4; INTERLEUKIN 5; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; PROSTAGLANDIN E2;

ANTIGEN PRESENTING CELL; AUTOIMMUNITY; CELL MATURATION; CELLULAR IMMUNITY; CONFERENCE PAPER; CONTROLLED STUDY; DENDRITIC CELL; ETIOLOGY; HELPER CELL; HUMAN; HUMAN CELL; IMMUNOMODULATION; IMMUNOTHERAPY; INFLAMMATION; LYMPHOCYTE PROLIFERATION; MONOCYTE; PRIORITY JOURNAL;

EID: 0030809617     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4757-9966-8_59     Document Type: Conference Paper

References (17)

1. Kaplan, G., G. Walsh, L.S. Guido, P. Meyn, R.A. Burkhardt, R.M. Abalos, J. Barker, P.A. Frindt, T.T. Fajardo, R. Celona, and Z.A. Cohn. 1992. Novel responses of human skin to intradermal recombinant granulocyte/macrophage colony-stimulating factor: Langerhans cell recruitment, keratinocyte growth and enhanced wound healing. J. Exp. Med. 175:1717-1728.
2. Peters, J.H., R.K.H. Gieseler, B. Thiele, and F. Steinbach. 1996. Dendritic cells: from ontogenetic orphans to myelomonocytic descendants. Immunol. Today 17:273- 278.
3. Fogh, K., T. Herlin, and K. Kragballe. 1989. Eicosanoids in skin of patients with atopic dermatitis: prostaglandin E2 and leukotriene B4 are present in biologically active concentrations. J. Allergy Clin. Immunol. 83:450-457.
4. Misra, N., M. Selvakumar, S. Singh, M. Bharadwaj, V. Ramesh, R.S. Misra, and I. Nath. 1995. Monocyte derived IL-10 and PGE2 are associated with the absence of Th1 cells and in vitro T cell suppression in lepromatous leprosy. Immunol. Lett. 48:123-128.
5. Foley, P., F. Kazazi, R. Biti, C. Sorrel, and A.L. Cunningham. 1992. HIV infection of monocytes inhibits the T-lymphocyte proliferative response to recall antigens, via production of eicosanoids. Immunology 75:391-397.
6. Snijdewint, F.G., P. Kalinski, E.A. Wierenga, J.D. Bos, and M.L. Kapsenberg. 1993. Prostaglandin E2 differentially modulates cytokine secretion profiles of human T helper lymphocytes. J. Immunol. 150:5321-5329.
7. van der Pouw Kraan, T.C., L.C. Boeije, R.J. Smeenk, J. Wijdenes, and L.A. Aarden. 1995. Prostaglandin-E2 is a potent inhibitor of human interleukin 12 production. J. Exp. Med. 181:775-779.
8. Sallusto, F. and A. Lanzavecchia. 1994. Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor a. J. Exp. Med. 179:1109-1118.
9. Fanslow, W.C., S. Srinivasan, R. Paxton, M.G. Gibson, M.K. Spriggs, and M.J. Armitage. 1994. Structural characteristics of CD40 ligand that determine biological function. Seminars Immunol. 6:267
10. Kalinski, P., C.M. Hilkens, E.A. Wierenga, T.C. van der Pouw-Kraan, R.A. van Lier, J.D. Bos, M.L. Kapsenberg, and F.G. Snijdewint. 1995. Functional maturation of human naive T helper cells in the absence of accessory cells. Generation of IL-4-producing T helper cells does not require exogenous IL-4. J. Immunol. 154:3753-3760.
11. Nygard, G., A. Larsson, B. Gerdin, S. Ejerblad, and T. Berglindh. 1992. Viability, prostaglandin E2 production, and protein handling in normal and inflamed human colonic mucosa cultured for up to 48 h in vitro. Scand. J Gastroenterol. 27:303-310.
12. Pugh, S. and G.A. Thomas. 1994. Patients with adenomatous polyps and carcinomas have increased colonic mucosal prostaglandin E2. Gut 35:675-678.
13. Schrey, M.P. and K.V. Patel. 1995. Prostaglandin E2 production and metabolism in human breast cancer cells and breast fibroblasts. Regulation by inflammatory mediators. Br. J. Cancer 72:1412-1419.
14. Graeme-Cook, F., A.K. Bhan, and N.L. Harris. 1993. Immunohistochemical characterization of intraepithelial and subepithelial mononuclear cells of the upper airways. Am. J. Pathol. 143:1416-1422.
15. van Haarst, J.M.W., H.C. Hoogsteden, H.J. de Wit, G.T. Verhoeven, C.E.G. Havenith, and H.A. Drexhage. 1994. Dendritic cells and their precursors isolated from human bronchoalveolar lavage: immunocytologic and functional properties. Am. J. Respir. Cell Mol. Biol. 11:344-350.
16. Cerio, R., C.E.M. Griffiths, K.D. Cooper, B.J. Nickoloff, and J.T. Headington. 1989. Characterization of factor XIIIa positive dermal dendritic cells in normal and inflamed skin. Br. J. Dermatol. 121:421-431.
17. Liblau, S.R., S.M. Singer, and H.O.McDevitt. 1995. Th1 and Th2 CD4+ T cells in the pathogenesis of organ-specific autoimmune diseases. Immunol. Today 16:34-42.