Effects of high-fat diets with different carbohydrate-to-protein ratios on energy homeostasis in rats with impaired brain melanocortin receptor activity

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 289, Issue 1 58-1, 2005, Pages

  Morens, C ^a   Keijzer, M ^a   De Vries, K ^a   Scheurink, A ^a   Van Dijk, G ^a  

^a UNIVERSITY OF GRONINGEN   (Netherlands)

Author keywords

Glucose tolerance; Ketogenic diet; Melanocortins; SHU9119

Indexed keywords

ADIPONECTIN; INSULIN; LEPTIN; MELANOCORTIN; MELANOCORTIN RECEPTOR; N ACETYL ALPHA INTERMEDIN[4-10]CYCLO[4 NORLEUCINE 5 ASPARTIC ACID 7 [3 (2 NAPHTHYL)ALANINE] 10 LYSINAMIDE];

ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CARBOHYDRATE ANALYSIS; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; FOOD INTAKE; GLUCOSE HOMEOSTASIS; GLUCOSE TOLERANCE; HYPERPHAGIA; INSULIN BLOOD LEVEL; LIPID DIET; MACRONUTRIENT; MALE; NERVE CONDUCTION; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROTEIN CARBOHYDRATE INTERACTION; PROTEIN CONTENT; PROTEIN DIET; RAT;

ANIMALS; BODY COMPOSITION; BODY WEIGHT; BRAIN; DIETARY CARBOHYDRATES; DIETARY FATS; DIETARY PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; EATING; ENERGY METABOLISM; GLUCOSE TOLERANCE TEST; GLYCOGEN; HOMEOSTASIS; HORMONES; HYPERPHAGIA; LIVER; MALE; MELANOCYTE-STIMULATING HORMONES; RATS; RATS, WISTAR; RECEPTORS, CORTICOTROPIN; RECEPTORS, MELANOCORTIN; SIGNAL TRANSDUCTION;

EID: 21044452354     PISSN: 03636119     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpregu.00774.2004     Document Type: Article

References (38)

1. Adage T, Scheurink AJW, de Boer SF, de Vries K, Konsman JP, Kuipers F, Adan RAH, Baskin DG, Schwartz MW, and van Dijk G. Hypothalamic, metabolic, and behavioral responses to pharmacological, inhibition of CNS melanocortin signaling in rats. J Neurosci 21: 3639-3645, 2001.
2. Anderson HL, Benevenga NJ, and Harper AE. Associations among food and protein intake, serine dehydratase, and plasma amino acids. Am J Physiol 214: 1008-1013, 1968.
3. Arita Y, Kihara S, Ouch N, Takahashi M, Maeda K, Miyagawa JI, Hotta K, Shimomura I, Nakamura T, Miyaoka K, Kuriyama H, Nishida M, Yamashita S, Okubo K, Matsubara K, Muraguchi M, Ohmoto Y, Funahashi T, and Matsuzawa Y. Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity. Biochem Biophys Res Commun 257: 79-83, 1999.
4. Bensaïd A, Tomé D, Gietzen DW, Even PC, Morens C, Gausserès N, and Fromentin G. Protein is more potent than carbohydrate for reducing appetite in rats. Physiol Behav 75: 577-582, 2002.
5. Botion LM, Kettelhut IC, and Migliorini RH. Reduced lipogenesis in rats fed a high-protein, carbohydrate-free diet: participation of the liver and four adipose tissues. Braz J Med Biol Res 25: 419-428, 1992.
6. Bray GA and Popkin BM. Dietary fat does promote obesity. Am J Clin Nutr 68: 1157-1173, 1998.
7. Butler AA, Marks DL, Fan W, Kuhn CM, Bartolome M, and Cone RD. Melanocortin-4 receptor is required for acute homeostatic responses to increased dietary fat. Nat Neurosci 4: 605-611, 2001.
8. Clegg DJ, Benoit SC, Air EL, Jackman A, Tso P, D'Alessio D, Woods SC, and Seeley RJ. Increased dietary fat attenuates the anorexic effects of intracerebroventricular injections of MTII. Endocrinology 144: 2941-2946, 2003.
9. Ferrannini E, Natali A, Bell P, Cavallo-Perin P, Lalic N, and Mingrone G. Insulin resistance and hypersecretion and obesity. European Group for the Study of Insulin Resistance (EGIR). J Clin Invest 100: 1166-1173, 1997.
10. Foster GD, Wyatt HR, Hill JO, McGuckin BG, Brill C, Mohammed BS, Szapary PO, Rader DJ, Edman JS, and Klein S. A randomized trial of a low-carbohydrate diet for obesity. N Engl J Med 348: 2082-2090, 2003.
11. Hagan MM, Rushing PA, Benoit SC, Woods SC, and Seeley RJ. Opioid involvement in the effect of AgRP-(83-132) on food intake and food selection. Am J Physiol Regul Integr Comp Physiol 280: R814-R821, 2001.
12. Hill JO, Fried SK, and Di Girolamo M. Effects of a high-fat diet on energy intake and expenditure in rats. Life Sci 13: 141-149, 1983.
13. Hill JO, Melanson EL, and Wyatt HT. Dietary fat intake and regulation of energy balance: implications for obesity. J Nutr 130: 284S-288S, 2000.
14. Hwa JJ, Ghibaudi L, Gao J, and Parker EM. Central melanocortin system modulates energy intake and expenditure of obese and lean Zucker rats. Am J Physiol Regul Integr Comp Physiol 281: R444-R451, 2001.
15. Jean C, Rome S, Mathé V, Huneau JF, Aattouri N, Fromentin G, Larue-Achagiotis C, and Tomé D. Metabolic evidence for adaptation to a high protein diet in rats. J Nutr 131: 91-98, 2001.
16. Kanarek RB and Hirsch E. Dietary induced overeating in experimental animals. Fed Proc 36: 154-158, 1977.
17. Koegler FH, Schaffhauser AO, Mynatt RL, York DA, and Bray GA. Macronutrient intake of the lethal yellow agouti (Ay/a) mouse. Physiol Behav 67: 809-812, 1999.
18. Kubota N, Terauchi Y, Yamauchi T, Kubota T, Moroi M, Matsui J, Eto K, Yamashita T, Kamon J, Satoh H, Yano W, Froguel P, Nagai R, Kimura S, Kadowaki T, and Noda T. Disruption of adiponectin causes insulin resistance and neointimal formation. J Biol Chem 19: 25863-25866, 2002.
19. Lacquemant C, Vasseur F, Leprêtre F, and Froguel P. Adipocytokins, obesity and development of type 2 diabetes. Med Sci 19: 809-17, 2003. [In French.]
20. Lingohr MK, Buettner R, and Rhodes CJ. Pancreatic β-cell growth and survival-a role in obesity-linked type 2 diabetes? Trends Mol Med 8: 375-384, 2002.
21. Maire B, Lioret S, Gartner A, and Delpeuch F: Nutritional transition and non-communicable diet-related chronic diseases in developing countries. Sante 12: 45-55, 2002. [In French.]
22. Mark J. Cellular warriors at the battle of the bulge. Science 299: 846-849, 2003.
23. Morens C, Gaudichon C, Fromentin G, Marsset-Baglieri A, Bensaïd A, Larue-Achagiotis C, Luengo C, and Tomé D. Daily delivery of dietary nitrogen to the periphery is stable in rats adapted to increased protein intake. Am J Physiol Endocrinol Metab 281: E826-E836, 2001.
24. Obici S, Feng Z, Tan J, Liu L, Karkanias G, and Rossetti L. Central melanocortin receptors regulate insulin action. J Clin Invest 108: 1079-1085, 2001.
25. Peters JC and Harper AE. Adaptation of rats to diets containing different levels of protein. J Nutr 115: 382-398, 1985.
26. Peters JC and Harper AE. Acute effects of dietary protein on food intake, tissue amino acids and brain serotonin. Am J Physiol Regul Integr Comp Physiol 252: R1725-R1733, 1987.
27. Rangwala SM, Rich-AS, Rhoades B, Shapiro JS, Obici S, Rossetti L, and Lazar MA. Abnormal glucose homeostasis due to chronic hyperresistinemia. Diabetes 53: 1937-1941, 2004.
28. Raposinho PD, Castillo E, d'Alleves V, Broqua P, Pralong FP, and Aubert ML. Chronic blockade of the melanocortin 4 receptor subtype leads to obesity independently of neuropeptide Y action, with no adverse effects on the gonadotropic and somatotropic axes. Endocrinology 141: 4419-4427, 2000.
29. Samama P, Rumennik L, and Grippo JF. The melanocortin receptor MCR4 controls fat consumption. Regul Pept 113: 85-88, 2003.
30. Seeley RJ and Woods SC. Monitoring of stored and available fuel by the CNS: implications for obesity. Nat Rev Neurosci 4: 901-909, 2003.
31. Steffens AB. A method for frequent sampling of blood and continuous infusions of fluids in the rat without disturbing the animals. Physiol Behav 4: 833-836, 1969.
32. Uhley VE and Jen KL. Changes in feeding efficiency and carcass composition in rats on repeated high fat diets. Int J Obes 13: 849-856, 1989.
33. Vaisse C, Clément K, Durand E, Hercberg S, Guy-Grand B, and Froguel P. Melanocortin-4 receptor mutations are a frequent and heterogenous cause of morbid obesity. J Clin Invest 106: 253-262, 2000.
34. Van Dijk G, Thiele TE, Donhahey LA, Campfield FJ, Smith P, Burn P, Bernstein IL, Wood SC, and Seeley RJ. Central infusions of leptin and GLP-1-(7-36) amide differentially stimulate c-FLI in the rat brain. Am J Physiol Regul Integr Comp Physiol 271: R1096-R1100, 1996.
35. Van Dijk G, de Vries K, Benthem L, Nyakas C, Buwalda B, and Scheurink AJW. Neuroendocrinology of insulin resistance: metabolic and endocrine aspects of adiposity. Eur J Pharmacol 480: 31-42, 2003.
36. Williams DL, Kaplan JM, and Grill HJ. The role of the dorsal vagal complex and the vagus nerve in feeding effects of melanocortin-3/4 receptor stimulation. Endocrinology 141: 1332-1337, 2000.
37. Wolf G. Adiponectin: a regulator of energy homeostasis. Nutr Rev 61: 290-292, 2003.
38. Zhang Y, Proenca R, Maffei M, Barone M, Leopold L, and Friedman JM. Positional cloning of the mouse obese gene and its human homologue. Nature 372: 425-432, 1994.