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Volumn 5, Issue 6, 2005, Pages 799-807

Peptide-based vaccination for colorectal cancer

Author keywords

Colorectal cancer; Immunotherapy; Peptide; Vaccine

Indexed keywords

ADJUVANT; BCG VACCINE; CANCER VACCINE; CHORIONIC GONADOTROPIN BETA SUBUNIT; CTLP ORIENTED PEPTIDE VACCINE; CYCLOPHOSPHAMIDE; DIPHTHERIA TOXOID; FREUND ADJUVANT; MUCIN 1; PEPTIDE; RECOMBINANT EPIDERMAL GROWTH FACTOR; SART 3 109 118; SART 3 315 323; SART 3 [109-118]; SART 3 [315-323]; SQUAMOUS CELL CARCINOMA ANTIGEN; SURVIVIN; SURVIVIN 2B; TETANUS TOXOID; UNCLASSIFIED DRUG;

EID: 21044443147     PISSN: 14712598     EISSN: None     Source Type: Journal    
DOI: 10.1517/14712598.5.6.799     Document Type: Review
Times cited : (15)

References (50)
  • 1
    • 13744256029 scopus 로고    scopus 로고
    • Chemoprevention of colorectal cancer: Ready for routine use?
    • ARBER N, LEVIN B: Chemoprevention of colorectal cancer: ready for routine use? Recent Results Cancer Res. (2005) 166:213-230.
    • (2005) Recent Results Cancer Res. , vol.166 , pp. 213-230
    • Arber, N.1    Levin, B.2
  • 2
    • 4644298960 scopus 로고    scopus 로고
    • Adjuvant therapy for stage II colon cancer: An elephant in the living room?
    • ZANIBONI A, LABIANCA R: Adjuvant therapy for stage II colon cancer: an elephant in the living room? Ann. Oncol. (2004) 15:1310-1318.
    • (2004) Ann. Oncol. , vol.15 , pp. 1310-1318
    • Zaniboni, A.1    Labianca, R.2
  • 3
    • 0038052092 scopus 로고    scopus 로고
    • Metastatic colorectal cancer systemic treatment in the new millennium
    • COUTINHO AK, ROCHA LIMA CM: Metastatic colorectal cancer systemic treatment in the new millennium. Cancer Control (2003) 10:224-238.
    • (2003) Cancer Control , vol.10 , pp. 224-238
    • Coutinho, A.K.1    Rocha Lima, C.M.2
  • 6
    • 0025735629 scopus 로고
    • The dendritic cell system and its role in immunogenicity
    • STEINMAN RM: The dendritic cell system and its role in immunogenicity. Annu. Rev. Immunol. (1991) 9:271-296.
    • (1991) Annu. Rev. Immunol. , vol.9 , pp. 271-296
    • Steinman, R.M.1
  • 7
    • 0028867835 scopus 로고
    • Manipulation of costimulatory signals to enhance antitumor T-cell responses
    • ALLISON JP, HURWITZ AA, LEACH DR: Manipulation of costimulatory signals to enhance antitumor T-cell responses. Curr. Opin. Immunol. (1995) 7:682-686.
    • (1995) Curr. Opin. Immunol. , vol.7 , pp. 682-686
    • Allison, J.P.1    Hurwitz, A.A.2    Leach, D.R.3
  • 9
    • 0025030522 scopus 로고
    • Presentation of exogenous antigen with class I major histocompatibility complex molecules
    • ROCK KL, GAMBLE S, ROTHSTEIN L: Presentation of exogenous antigen with class I major histocompatibility complex molecules. Science (1990) 249:918-921.
    • (1990) Science , vol.249 , pp. 918-921
    • Rock, K.L.1    Gamble, S.2    Rothstein, L.3
  • 10
    • 0026571235 scopus 로고
    • MHC class I-restricted presentation of exogenous antigen by thymic antigen-presenting cells in vitro and in vivo
    • GRANT EP, ROCK KL: MHC class I-restricted presentation of exogenous antigen by thymic antigen-presenting cells in vitro and in vivo. J. Immunol. (1992) 148:13-18.
    • (1992) J. Immunol. , vol.148 , pp. 13-18
    • Grant, E.P.1    Rock, K.L.2
  • 11
    • 0027284742 scopus 로고
    • Characterization of antigen-presenting cells that present exogenous antigens in association with class I MHC molecules
    • ROCK KL, ROTHSTEIN L, GAMBLE S, FLEISCHACKER C: Characterization of antigen-presenting cells that present exogenous antigens in association with class I MHC molecules. J. Immunol. (1993) 150:438-446.
    • (1993) J. Immunol. , vol.150 , pp. 438-446
    • Rock, K.L.1    Rothstein, L.2    Gamble, S.3    Fleischacker, C.4
  • 12
    • 0028052101 scopus 로고
    • Phagocytic processing of exogenous particulate antigens by macrophages for presentation by class I MHC molecules
    • HARDING CV, SONG R: Phagocytic processing of exogenous particulate antigens by macrophages for presentation by class I MHC molecules. J. Immunol. (1994) 153:4925-4933.
    • (1994) J. Immunol. , vol.153 , pp. 4925-4933
    • Harding, C.V.1    Song, R.2
  • 13
    • 0028910938 scopus 로고
    • A phagosome-to-cytosol pathway for exogenous antigens presented on MHC class I molecules
    • KOVACSOVIC-BANKOWSKI M, ROCK KL: A phagosome-to-cytosol pathway for exogenous antigens presented on MHC class I molecules. Science (1995) 267:243-245.
    • (1995) Science , vol.267 , pp. 243-245
    • Kovacsovic-Bankowski, M.1    Rock, K.L.2
  • 15
    • 0025918153 scopus 로고
    • Helper T-cell subsets: Phenotype, function and the role of lymphokines in regulating their development
    • SWAIN SL, BRADLEY LM, CROFT M et al.: Helper T-cell subsets: phenotype, function and the role of lymphokines in regulating their development. Immunol. Rev. (1991) 123:115-144.
    • (1991) Immunol. Rev. , vol.123 , pp. 115-144
    • Swain, S.L.1    Bradley, L.M.2    Croft, M.3
  • 16
    • 0027302705 scopus 로고
    • Immunological memory
    • MACKAY CR: Immunological memory. Adv. Immunol. (1993) 53:217-265.
    • (1993) Adv. Immunol. , vol.53 , pp. 217-265
    • Mackay, C.R.1
  • 17
    • 0041485051 scopus 로고    scopus 로고
    • Granulocyte-macrophage-colony-stimulating factor enhances immune responses to melanoma-associated peptides in vivo
    • JAGER E, RINGHOFFER M, DIENES HP et al.: Granulocyte-macrophage-colony- stimulating factor enhances immune responses to melanoma-associated peptides in vivo. Int. J. Cancer (1996) 67:54-62.
    • (1996) Int. J. Cancer , vol.67 , pp. 54-62
    • Jager, E.1    Ringhoffer, M.2    Dienes, H.P.3
  • 18
    • 0036847689 scopus 로고    scopus 로고
    • Toxicity, immunogenicity, and induction of E75-specific tumor-lytic CTLs by HER-2 peptide E75 (369-377) combined with granulocyte macrophage colony-stimulating factor in HLA-A2 patients with metastatic breast and ovarian cancer
    • MURRAY JL, GILLOGLY ME, PRZEPIORKA D et al.: Toxicity, immunogenicity, and induction of E75-specific tumor-lytic CTLs by HER-2 peptide E75 (369-377) combined with granulocyte macrophage colony-stimulating factor in HLA-A2 patients with metastatic breast and ovarian cancer. Clin. Cancer Res. (2002) 8:3407-3418.
    • (2002) Clin. Cancer Res. , vol.8 , pp. 3407-3418
    • Murray, J.L.1    Gillogly, M.E.2    Przepiorka, D.3
  • 20
    • 33745758097 scopus 로고    scopus 로고
    • Phase I clinical study of anti-apoptosis protein, survivin-derived peptide vaccine therapy for patients with advanced or recurrent colorectal cancer
    • TSURUMA T, HATA F, TORIGOE T et al.: Phase I clinical study of anti-apoptosis protein, survivin-derived peptide vaccine therapy for patients with advanced or recurrent colorectal cancer. J. Transl. Med. (2004) 2:19-29. Clinical trial of peptide vaccine therapy for patients with colorectal cancer.
    • (2004) J. Transl. Med. , vol.2 , pp. 19-29
    • Tsuruma, T.1    Hata, F.2    Torigoe, T.3
  • 22
    • 10744233222 scopus 로고    scopus 로고
    • Vaccination with autologous tumor-derived heat-shock protein Gp96 after liver resection for metastatic colorectal cancer
    • MAZZAFERRO V, COPPA J, CARRABBA MG et al.: Vaccination with autologous tumor-derived heat-shock protein Gp96 after liver resection for metastatic colorectal cancer. Clin. Cancer Res. (2003) 9:3235-3245. A clinical trial that was carried out using autologous tumour-derived HSPPC-96 to vaccinate patients after resection of liver metastases of colorectal carcinoma.
    • (2003) Clin. Cancer Res. , vol.9 , pp. 3235-3245
    • Mazzaferro, V.1    Coppa, J.2    Carrabba, M.G.3
  • 23
    • 6044242149 scopus 로고    scopus 로고
    • The spontaneous CD8 T-cell response to HLA-A2-restricted NY-ESO-1b peptide in hepatocellular carcinoma patients
    • SHANG XY, CHEN HS, ZHANG HG et al.: The spontaneous CD8 T-cell response to HLA-A2-restricted NY-ESO-1b peptide in hepatocellular carcinoma patients. Clin. Cancer Res. (2004) 10:6945-6955.
    • (2004) Clin. Cancer Res. , vol.10 , pp. 6945-6955
    • Shang, X.Y.1    Chen, H.S.2    Zhang, H.G.3
  • 24
    • 11344288398 scopus 로고    scopus 로고
    • Enumerating antigen-specific T-cell responses in peripheral blood: A comparison of peptide MHC tetramer, ELISpot, and intracellular cytokine analysis
    • HOBEIKA AC, MORSE MA, OSADA T et al.: Enumerating antigen-specific T-cell responses in peripheral blood: a comparison of peptide MHC tetramer, ELISpot, and intracellular cytokine analysis. J. Immunother. (2005) 28:63-72. Investigation of antigen-specific T cell responses: peptide/MHC tetramer analysis, ELISPOT assay and intracellular cytokine flow cytometry analysis.
    • (2005) J. Immunother. , vol.28 , pp. 63-72
    • Hobeika, A.C.1    Morse, M.A.2    Osada, T.3
  • 25
    • 0037314635 scopus 로고    scopus 로고
    • Enzyme-linked immunospot, cytokine flow cytometry, and tetramers in the detection of T-cell responses to a dendritic cell-based multipeptide vaccine in patients with melanoma
    • WHITESIDE TL, ZHAO Y, TSUKISHIRO T, ELDER EM, GOODING W, BAAR J: Enzyme-linked immunospot, cytokine flow cytometry, and tetramers in the detection of T-cell responses to a dendritic cell-based multipeptide vaccine in patients with melanoma. Clin. Cancer Res. (2003) 9:641-649. Investigation of antigen-specific T cell responses: peptide/MHC tetramer analysis, ELISPOT assay and intracellular cytokine flow cytometry analysis.
    • (2003) Clin. Cancer Res. , vol.9 , pp. 641-649
    • Whiteside, T.L.1    Zhao, Y.2    Tsukishiro, T.3    Elder, E.M.4    Gooding, W.5    Baar, J.6
  • 26
    • 0033579934 scopus 로고    scopus 로고
    • Tumor regressions observed in patients with metastatic melanoma treated with an antigenic peptide encoded by gene MAGE-3 and presented by HLA-A1
    • MARCHAND M, VAN BAREN N, WEYNANTS P et al.: Tumor regressions observed in patients with metastatic melanoma treated with an antigenic peptide encoded by gene MAGE-3 and presented by HLA-A1. Int. J. Cancer (1999) 80:219-230.
    • (1999) Int. J. Cancer , vol.80 , pp. 219-230
    • Marchand, M.1    Van Baren, N.2    Weynants, P.3
  • 27
    • 0029925375 scopus 로고    scopus 로고
    • Prognostic value of tumor infiltrating lymphocytes in the vertical growth phase of primary cutaneous melanoma
    • CLEMENTE CG, MIHM MC JR, BUFALINO R, ZURRIDA S, COLLINI P, CASCINELLI N: Prognostic value of tumor infiltrating lymphocytes in the vertical growth phase of primary cutaneous melanoma. Cancer (1996) 77:1303-1310.
    • (1996) Cancer , vol.77 , pp. 1303-1310
    • Clemente, C.G.1    Mihm Jr., M.C.2    Bufalino, R.3    Zurrida, S.4    Collini, P.5    Cascinelli, N.6
  • 28
    • 0034544532 scopus 로고    scopus 로고
    • A shift in the phenotype of melan-A-specific CTL identifies melanoma patients with an active tumor-specific immune response
    • DUNBAR PR, SMITH CL, CHAO D et al.: A shift in the phenotype of melan-A-specific CTL identifies melanoma patients with an active tumor-specific immune response. J. Immunol. (2000) 165:6644-6652.
    • (2000) J. Immunol. , vol.165 , pp. 6644-6652
    • Dunbar, P.R.1    Smith, C.L.2    Chao, D.3
  • 29
    • 0032476616 scopus 로고    scopus 로고
    • Ex vivo staining of metastatic lymph nodes by class I major histocompatibility complex tetramers reveals high numbers of antigen-experienced rumor-specific cytolytic T lymphocytes
    • ROMERO P, DUNBAR PR, VALMORI D et al.: Ex vivo staining of metastatic lymph nodes by class I major histocompatibility complex tetramers reveals high numbers of antigen-experienced rumor-specific cytolytic T lymphocytes. J. Exp. Med. (1998) 188:1641-1650.
    • (1998) J. Exp. Med. , vol.188 , pp. 1641-1650
    • Romero, P.1    Dunbar, P.R.2    Valmori, D.3
  • 31
    • 0030000007 scopus 로고    scopus 로고
    • A Phase I trial of a synthetic mucin peptide vaccine. Induction of specific immune reactivity in patients with adenocarcinoma
    • GOYDOS JS, ELDER E, WHITESIDE TL, FINN OJ, LOTZE MT: A Phase I trial of a synthetic mucin peptide vaccine. Induction of specific immune reactivity in patients with adenocarcinoma. J. Surg. Res. (1996) 63:298-304. Clinical trial of peptide vaccine therapy for patients with colorectal cancer.
    • (1996) J. Surg. Res. , vol.63 , pp. 298-304
    • Goydos, J.S.1    Elder, E.2    Whiteside, T.L.3    Finn, O.J.4    Lotze, M.T.5
  • 32
    • 0031775979 scopus 로고    scopus 로고
    • A novel cancer vaccine composed of human-recombinant epidermal growth factor linked to a carrier protein: Report of a pilot clinical trial
    • GONZALEZ G, CROMBET T, CATALA M et al.: A novel cancer vaccine composed of human-recombinant epidermal growth factor linked to a carrier protein: Report of a pilot clinical trial. Ann. Oncol. (1998) 9:431-435. Clinical trial of peptide vaccine therapy for patients with colorectal cancer.
    • (1998) Ann. Oncol. , vol.9 , pp. 431-435
    • Gonzalez, G.1    Crombet, T.2    Catala, M.3
  • 33
    • 2342564465 scopus 로고    scopus 로고
    • A Phase I trial of cytotoxic T-lymphocyte precursor-oriented peptide vaccines for colorectal carcinoma patients
    • SATO Y, MAEDA Y, SHOMURA H et al.: A Phase I trial of cytotoxic T-lymphocyte precursor-oriented peptide vaccines for colorectal carcinoma patients. Br. J. Cancer (2004) 90:1334-1342. Clinical trial of peptide vaccine therapy for patients with colorectal cancer.
    • (2004) Br. J. Cancer , vol.90 , pp. 1334-1342
    • Sato, Y.1    Maeda, Y.2    Shomura, H.3
  • 34
    • 0347915729 scopus 로고    scopus 로고
    • Vaccination with predesignated or evidence-based peptides for patients with recurrent gynecologic cancers
    • TSUDA N, MOCHIZUKI K, HARADA M et al.: Vaccination with predesignated or evidence-based peptides for patients with recurrent gynecologic cancers. J. Immunother. (2004) 27:60-72.
    • (2004) J. Immunother. , vol.27 , pp. 60-72
    • Tsuda, N.1    Mochizuki, K.2    Harada, M.3
  • 35
    • 0035992254 scopus 로고    scopus 로고
    • Active specific immunotherapy with a β-human chorionic gonadotropin peptide vaccine in patients with metastatic colorectal cancer: Antibody response is associated with improved survival
    • MOULTON HM, YOSHIHARA PH, MASON DH, IVERSEN PL, TRIOZZI PL: Active specific immunotherapy with a β-human chorionic gonadotropin peptide vaccine in patients with metastatic colorectal cancer: antibody response is associated with improved survival. Clin. Cancer Res. (2002) 8:2044-2051. Clinical trial of peptide vaccine therapy for patients with colorectal cancer.
    • (2002) Clin. Cancer Res. , vol.8 , pp. 2044-2051
    • Moulton, H.M.1    Yoshihara, P.H.2    Mason, D.H.3    Iversen, P.L.4    Triozzi, P.L.5
  • 36
    • 0035679233 scopus 로고    scopus 로고
    • Induction of cellular immune responses to tumor cells and peptides in colorectal cancer patients by vaccination with SART3 peptides
    • MIYAGI Y, IMAI N, SASATOMI T et al.: Induction of cellular immune responses to tumor cells and peptides in colorectal cancer patients by vaccination with SART3 peptides. Clin. Cancer Res. (2001) 7:3950-3962. Clinical trial of peptide vaccine therapy for patients with colorectal cancer.
    • (2001) Clin. Cancer Res. , vol.7 , pp. 3950-3962
    • Miyagi, Y.1    Imai, N.2    Sasatomi, T.3
  • 37
    • 0031890206 scopus 로고    scopus 로고
    • Immunologic and therapeutic evaluation of a synthetic peptide vaccine for the treatment of patients with metastatic melanoma
    • ROSENBERG SA, YANG JC, SCHWARTZENTRUBER DJ et al.: Immunologic and therapeutic evaluation of a synthetic peptide vaccine for the treatment of patients with metastatic melanoma. Nat. Med. (1998) 4:321-327.
    • (1998) Nat. Med. , vol.4 , pp. 321-327
    • Rosenberg, S.A.1    Yang, J.C.2    Schwartzentruber, D.J.3
  • 38
    • 0031941423 scopus 로고    scopus 로고
    • Vaccination of melanoma patients with peptide- or tumor lysate-pulsed dendritic cells
    • NESTLE FO, ALIJAGIC S, GILLIET M et al.: Vaccination of melanoma patients with peptide- or tumor lysate-pulsed dendritic cells. Nat. Med. (1998) 4:328-332.
    • (1998) Nat. Med. , vol.4 , pp. 328-332
    • Nestle, F.O.1    Alijagic, S.2    Gilliet, M.3
  • 39
    • 0033579934 scopus 로고    scopus 로고
    • Tumor regressions observed in patients with metastatic melanoma treated with an antigenic peptide encoded by gene MAGE-3 and presented by HLA-A1
    • MARCHAND M, VAN BAREN N, WEYNANTS P et al.: Tumor regressions observed in patients with metastatic melanoma treated with an antigenic peptide encoded by gene MAGE-3 and presented by HLA-A1. Int. J. Cancer (1999) 80:219-230.
    • (1999) Int. J. Cancer , vol.80 , pp. 219-230
    • Marchand, M.1    Van Baren, N.2    Weynants, P.3
  • 40
    • 0032724112 scopus 로고    scopus 로고
    • Phase I trial of a MART-I peptide vaccine with incomplete Freund's adjuvant for resected high-risk melanoma
    • WANG F, BADE E, KUNIYOSHI C et al.: Phase I trial of a MART-I peptide vaccine with incomplete Freund's adjuvant for resected high-risk melanoma. Clin. Cancer Res. (1999) 5:2756-2765.
    • (1999) Clin. Cancer Res. , vol.5 , pp. 2756-2765
    • Wang, F.1    Bade, E.2    Kuniyoshi, C.3
  • 41
    • 0038691976 scopus 로고    scopus 로고
    • Monitoring CD8 T cell responses to NY-ESO-1: Correlation of humoral and cellular immune responses
    • JAGER E, NAGATA Y, GNJATIC S et al.: Monitoring CD8 T cell responses to NY-ESO-1: correlation of humoral and cellular immune responses. Proc. Natl. Acad. Sci. USA (2000) 97:4760-4765.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 4760-4765
    • Jager, E.1    Nagata, Y.2    Gnjatic, S.3
  • 42
    • 0036281671 scopus 로고    scopus 로고
    • An HLA-A24-restricted cytotoxic T lymphocyte epitope of a tumor-associated protein, survivin
    • HIROHASHI Y, TORIGOE T, MAEDA A et al.: An HLA-A24-restricted cytotoxic T lymphocyte epitope of a tumor-associated protein, survivin. Clin. Cancer Res. (2002) 8:1731-1739.
    • (2002) Clin. Cancer Res. , vol.8 , pp. 1731-1739
    • Hirohashi, Y.1    Torigoe, T.2    Maeda, A.3
  • 43
    • 20044366918 scopus 로고    scopus 로고
    • A potent immunogenic general cancer vaccine that targets survivin, an inhibitor of apoptosis proteins
    • IDENOUE S, HIROHASHI Y, TORIGOE T et al.: A potent immunogenic general cancer vaccine that targets survivin, an inhibitor of apoptosis proteins. Clin. Cancer Res. (2005) 15:1474-1482.
    • (2005) Clin. Cancer Res. , vol.15 , pp. 1474-1482
    • Idenoue, S.1    Hirohashi, Y.2    Torigoe, T.3
  • 45
    • 3042739497 scopus 로고    scopus 로고
    • Simultaneous CD8+ T cell responses to multiple tumor antigen epitopes in a multipeptide melanoma vaccine
    • VALMORI D, DUTOIT V, AYYOUB M et al.: Simultaneous CD8+ T cell responses to multiple tumor antigen epitopes in a multipeptide melanoma vaccine. Cancer Immun. (2003) 3:15.
    • (2003) Cancer Immun. , vol.3 , pp. 15
    • Valmori, D.1    Dutoit, V.2    Ayyoub, M.3
  • 46
    • 17044440353 scopus 로고    scopus 로고
    • Peptide vaccination after repeated resection of metastases can induce a prolonged relapse-free interval in melanoma patients
    • LETSCH A, KEILHOLZ U, FLUCK M et al.: Peptide vaccination after repeated resection of metastases can induce a prolonged relapse-free interval in melanoma patients. Int. J. Cancer (2005) 114(6):936-941. Clinical trial of adjuvant peptide vaccine therapy that induced a prolonged relapse-free interval.
    • (2005) Int. J. Cancer , vol.114 , Issue.6 , pp. 936-941
    • Letsch, A.1    Keilholz, U.2    Fluck, M.3
  • 47
    • 0033616482 scopus 로고    scopus 로고
    • Active specific immunotherapy for stage II and stage III human colon cancer. A randomized trial
    • VERMORKEN JB, CLAESSEN AM, VAN TINTEREN H et al.: Active specific immunotherapy for stage II and stage III human colon cancer. A randomized trial. Lancet (1999) 30:345-350. Clinical trial of adjuvant immunotherapy in surgically resected patients with an autologous tumour cell-BCG vaccine in colon cancer.
    • (1999) Lancet , vol.30 , pp. 345-350
    • Vermorken, J.B.1    Claessen, A.M.2    Van Tinteren, H.3
  • 48
    • 0027512782 scopus 로고
    • Adjuvant active specific immunotherapy for human colorectal cancer: 6.5-Year median follow-up of a Phase III prospectively randomized trial
    • HOOVER HC, BRANDHORST JS, PETERS LC et al.: Adjuvant active specific immunotherapy for human colorectal cancer: 6.5-year median follow-up of a Phase III prospectively randomized trial. J. Clin. Oncol. (1993) 11:390-399. Clinical trial of adjuvant immunotherapy in surgically resected patients with an autologous tumour cell-BCG vaccine in colon cancer.
    • (1993) J. Clin. Oncol. , vol.11 , pp. 390-399
    • Hoover, H.C.1    Brandhorst, J.S.2    Peters, L.C.3
  • 49
    • 0033985949 scopus 로고    scopus 로고
    • Adjuvant active specific immunotherapy for stage II and III colon cancer with an autologous tumor cell vaccine: Eastern cooperative oncology group study E5283
    • HARRIS JE, RYAN L, HOOVER HC et al.: Adjuvant active specific immunotherapy for stage II and III colon cancer with an autologous tumor cell vaccine: Eastern cooperative oncology group study E5283. J. Clin. Oncol. (2000) 18:148-157. Clinical trial of adjuvant immunotherapy in surgically resected patients with an autologous tumour cell-BCG vaccine in colon cancer.
    • (2000) J. Clin. Oncol. , vol.18 , pp. 148-157
    • Harris, J.E.1    Ryan, L.2    Hoover, H.C.3
  • 50
    • 0038307824 scopus 로고    scopus 로고
    • Immunotherapy as part of combinations for the treatment of cancer
    • MITCHELL MS: Immunotherapy as part of combinations for the treatment of cancer. Int. Immunopharmacol. (2003) 3:1051-1059.
    • (2003) Int. Immunopharmacol. , vol.3 , pp. 1051-1059
    • Mitchell, M.S.1


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