Micropet imaging: In vivo biochemistry in small animals

Journal of Neural Transmission

Volumn 112, Issue 3, 2005, Pages 319-330

  Sossi, V ^a,b   Ruth, T J ^a  

^a TRIUMF   (Canada)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Positron emission tomography; Radiotracers; Small animal imaging

Indexed keywords

DIHYDROTETRABENAZINE; DOPAMINE 2 RECEPTOR BLOCKING AGENT; LUTETIUM ORTHOSILICATE; METHYLPHENIDATE; RACLOPRIDE; TRACER; UNCLASSIFIED DRUG;

ACCURACY; AUTORADIOGRAPHY; BINDING KINETICS; BIOCHEMISTRY; BLOOD BRAIN BARRIER; BRAIN FUNCTION; COMPUTED TOMOGRAPHY SCANNER; COMPUTER; COMPUTER ASSISTED TOMOGRAPHY; CONFERENCE PAPER; DRUG DESIGN; DRUG DISTRIBUTION; DRUG METABOLISM; EXPERIMENTAL MODEL; HUMAN; MEDICAL INSTRUMENTATION; MICRODIALYSIS; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; OPTICAL RESOLUTION; PARKINSON DISEASE; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN SYNTHESIS; RADIOACTIVITY; RELIABILITY; RODENT; SENSITIVITY AND SPECIFICITY;

ANIMALS; BRAIN CHEMISTRY; DISEASE MODELS, ANIMAL; HUMANS; MICE; POSITRON-EMISSION TOMOGRAPHY; RATS; SPECIES SPECIFICITY;

EID: 20944433389     PISSN: 03009564     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00702-004-0272-2     Document Type: Conference Paper

References (42)

1. Camborde ML, Rahmim A, Newport DF, Siegel S, Buckley KR, Vandervoort E, Ruth TJ, Sossi V (2004) Effect of normalization method on image uniformity and distribution volume ratio estimates on microPET® R4. 2004 IEEE/MIC Meeting Rome, Italy
2. Campbell B (1995) Drug development and positron emission tomography. In: Comar D (ed) PET for drug development and evaluation. Kluwer, Dordrecht, pp 25-36
3. Chan GL, Holden JE, Stoessl AJ, Samii A, Doudet DJ, Dobko T et al. (1999) Reproducibility studies with 11C-DTBZ, a monoamine vesicular transporter inhibitor in healthy human subjects. J Nucl Med 40: 283-289
4. Chatziioannou AF (2002) PET scanners dedicated to molecular imaging of small animal models. Mol Imaging Biol 4: 47-63
5. Cherry SR (2001) Fundamentals of positron emission tomography and applications in preclinical drug development. J Clin Pharmacol 41: 482-491
6. Cherry SR, Gambhir SS (2001) Use of positron emission tomography in animal research. ILAR J 42: 219-232
7. del Guerra A, Belcari N (2002) Advances in animal PET scanners. Q J Nucl Med 46(1): 35-47
8. Dolbier WR, Li AR, Koch CJ, Kachur AV (2001) [18F]-EF5, a marker for PET detection of hypoxia: synthesis of precursor and a new fluorination procedure. Appl Radiat Isot 54(1): 73-80
9. Frese T, Rouze NC, Bouman CA, Sauer K, Hutchins GD (2003) Quantitative comparison of FBP, EM, and Bayesian reconstruction algorithms for the IndyPET scanner. IEEE Trans Med Imaging 22: 258-276
10. Herschman HR (2003) Molecular imaging: looking at problems, seeing solutions. Science 24; 302(5645): 605-608
11. Herschman HR (2004) PET reporter genes for noninvasive imaging of gene therapy, cell tracking and transgenic analysis. Crit Rev Oncol/Hematol 51: 191-204
12. Hume SP, Gunn RN, Jones T (1998) Pharmacological constraints associated with positron emission tomographic scanning of small laboratory animals. Eur J Nucl Med 25: 173-176
13. Hume SP, Myers R (2002) Dedicated small animal scanners: a new tool for drug development? Curr Pharm Des 8: 1497-1511
14. Jacobs AH, Li H, Winkeler A, Hilker R, Knoess C, Ruger A, Galldiks N, Schaller B, Sobesky J, Kracht L, Monfared P, Klein M, Vollmar S, Bauer B, Wagner R, Graf R, Wienhard K, Herholz K, Heiss WD (2003) PET-based molecular imaging in neuroscience. Eur J Nucl Med Mol Imaging 30: 1051-1065
15. Jeavons AP, Chandler RA, Dettmar CAR (1999) A 3D HIDAC-PET camera with sub-millimetre resolution for imaging small animals. IEEE Trans Nucl Sci 46; 3: 468-473
16. Kawamura K, Elsinga PH, Kobayashi T, Ishii S, Wang WF, Matsuno K, Vaalburg W, Ishiwata K (2003) Synthesis and evaluation of 11C- and 18F-labeled 1-[2-(4-alkoxy-3-methoxyphenyl)ethyl]-4-(3-phenylpropyl)piperazines as sigma receptor ligands for positron emission tomography studies. Nucl Med Biol 30: 273-284
17. Knoess C, Siegel S, Smith A, Newport D, Richerzhagen N, Winkeler A, Jacobs A, Goble RN, Graf R, Wienhard K, Heiss WD (2003) Performance evaluation of the microPET R4 PET scanner for rodents. Eur J Nucl Med Mol Imaging 30(5): 737-747
18. Langstrom B, Bergstrom M, Hartvig P, Valind S, Watanabe Y (1995) Is PET a tool for drug evaluation. In: Comar D (ed) PET for drug development and evaluation. Kluwer, Dordrecht
19. Lecomte R, Bérard P, Pepin CM, Bélanger F, Cadorette J, Convert L, Lepage MD, Leroux JD, Michaud JB, Pratte JF, Robert S, Rouleau D, Selivanov VV, Tétrault MA, Fontaine R (2004) Design considerations for a combined, APD-based μPET/μCT Scanner. Proceedings, 2004 IEEE/MIC Meeting, Rome, Italy
20. Lee CS, Samii A, Sossi V, Ruth TJ, Schulzer M, Holden JE, Wudel J, Pal P, de la Fuente-Fernadez R, Calne DB, Stoessl AJ (2000) In vivo PET evidence for compensatory changes in presynaptic dopaminergic nerve terminals in Parkinson's disease. Ann Neurol 47: 493-503
21. Logan J, Fowler JS, Volkow ND, Wang GJ, Ding YS, Alexoff DL (1996) Distribution volume ratios without blood sampling from graphical analysis of PET data. J Cereb Blood Flow Metab 16(5): 834-840
22. Mackewn JE, Strul D, Hallett WA, Halsted P, Page TA, Keevil SF, Williams SC, Cherry SR, Marsden PK (2004) Design and development of an MR compatible PET scanner for imaging small animals. Proceedings, 2004 IEEE/MIC Meeting, Rome, Italy
23. McElroy DP, Pimpl W, Djelassi M, Pichler BJ, Rafecas M, Schuler T, Ziegler SI (2003) First results from MADPET-II: a novel detector and readout system for high resolution small animal PET. Nuclear Science Symposium Conference Record, October 19-25, 2003. IEEE Volume 3, pp 2043-2047
24. Miyake H, Tolcher A, Gleave ME (1999) Antisense Bcl-2 oligodeoxynucleotides inhibit progression to androgen-independence after castration in the Shionogi tumor model. Cancer Res 59: 4030-4034
25. Myers R (2001) The biological application of small animal PET imaging. Nucl Med Biol 28: 585-593
26. Nikolaus S, Larisch R, Beu M, Forutan F, Vosberg H, Muller-Gartner HW (2003) Bilateral increase in striatal dopamine D2 receptor density in the 6-hydroxydopamine-lesioned rat: a serial in vivo investigation with small animal PET. Eur J Nucl Med Mol Imaging 30: 390-395
27. Okarvi SM (2001) Recent progress in fluorine-18 labelled peptide radiopharmaceuticals. Eur J Nucl Med 28: 929-938
28. Rowland DJ, Lewis JS, Welch MJ (2002) Molecular imaging: the application of small animal positron emission tomography. J Cell Biochem [Suppl] 39: 110-115
29. Schafers M, Ametamey S, Schubiger PA (2003) Sensitivity or resolution - or both? "State of the Art Imaging Using Small Animal PET Scanners" report on the 10th Bottstein Colloquium/2nd Workshop on Basic Research in Molecular Imaging, October 11-12, 2002, Villigen, Switzerland. Eur J Nucl Med Mol Imaging 30: 482-483
30. Seidel J, Vaquera JJ, Green MV (2003) Resolution uniformity and sensitivity of the NIH ATLAS small animal PET scanner: comparison to simulated LSO scanners without depth-of-interaction capability. IEEE Transact Nucl Sci 50(5): 1347-1350
31. 11C]carfentanil. J Labelled Cpd Radiopharm 46(9): 837-842
32. Studenov AR, Jivan S, Adam MJ, Buckley KR, Ruth TJ (2004) Studies of the mechanism of the In-Loop synthesis of radiopharmaceuticals. Appl Radiat Isot 61: 1195-1201
33. Tai YC, Chatziioannou AF, Yang Y, Silverman RW, Meadors K, Siegel S, Newport DF, Stickel JR, Cherry SR (2003) MicroPET II: design, development and initial performance of an improved microPET scanner for small-animal imaging. Phys Med Biol 48: 1519-1537
34. Tsyganov EN, Antich PP, Kulkarni PV, Mason RP, Parkey RW, Seliounine SY, Shay JW, Soesbe TC, Zinchenko AI (2004) Micro-SPECT combined with 3D optical imaging. Proceedings, 2004 IEEE/MIC Meeting, Rome, Italy
35. Umegaki H, Ishiwata K, Ogawa O, Ingram DK, Roth GS, Oda K, Kurotani S, Kawamura K, Wang WF, Ikari H, Senda M, Iguchi A (2003) Longitudinal follow-up study of adenoviral vector-mediated gene transfer of dopamine D2 receptors in the striatum in young, middle-aged, and aged rats: a positron emission tomography study. Neuroscience 121: 479-486
36. 3H]methoxytetrabenazine: a high specific activity ligand for estimating monoaminergic neuronal integrity. Neuroscience 68: 955-962
37. Vander Borght T, Kilbourn M, Desmond T, Kuhl D, Frey K (1995b) The vesicular monoamine transporter is not regulated by dopaminergic drug treatments. Eur J Pharmacol 294: 577-583
38. van der Weerdt AP, Klein LJ, Boellaard R, Visser CA, Visser FC, Lammertsma AA (2001) Image-derived input functions for determination of MRGlu in cardiac (18)F-FDG PET scans. J Nucl Med 42(11): 1622-1629
39. Votaw J, Byas-Smith M, Hua J, Voll R, Martarello L, Levey AI, Bowman FD, Goodman M (2003) Interaction of isoflurane with the dopamine transporter. Anesthesiology 98(2): 404-411
40. Weber S, Herzog H, Cremer M, Engels R, Hamacher K, Kehren F, Muehlensiepen H, Ploux L, Reinartz R, Reinhart P, Rongen F, Sonnenberg F, Coenen HH, Halling H (1999) First results from MADPET-II: a novel detector and readout system for high resolution small animal PET. IEEE Transact Nucl Sci 46(4): 1177-1183
41. 11C]iodomethane: a remarkably simple captive solvent method. Nucl Med Biol 27(6): 529-532
42. Woody CL, Fontaine R, Junnarkar S, Kandasamy A, Kriplani A, Krishnamoorthy S, Lecomte R, O'Connor P, Page C, Pratte J-F, Purschke M, Radeka V, Rampil I, Schlyer DJ, Shokouhi S, Southekal S, Stoll SP, Vaska P, Villaneuva A, Yul B (2004) The RatCAP conscious small animal PET tomography. Proceedings, 2004 IEEE/MIC Meeting, Rome, Italy