Potential antitumor agents. 37. Synthesis and antitumor activity of guanylhydrazones from imidazo[2,1-b]thiazoles and from the new heterocyclic system thiazolo[2′,3′:2,3]imidazo[4,5-c]quinoline

Journal of Medicinal Chemistry

Volumn 48, Issue 8, 2005, Pages 3085-3089

  Andreani, Aldo ^a   Granaiola, Massimiliano ^a   Leoni, Alberto ^a   Locatelli, Alessandra ^a   Morigi, Rita ^a   Rambaldi, Mirella ^a   Lenaz, Giorgio ^a   Fato, Romana ^a   Bergamini, Christian ^a   Farruggia, Giovanna ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

2 CHLORO 6 (2,5 DIMETHOXY 4 NITROPHENYL)IMIDAZO[2,1 B]THIAZOLE 5 CARBALDEHYDE; AMIDINOHYDRAZONE; IMIDAZO[2,1 B]THIAZOLE DERIVATIVE; QUINONE DERIVATIVE; THIAZOLO[2',3':2,3]IMIDAZO[4,5 C]QUINONE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CONTROLLED STUDY; CYTOTOXICITY; ENZYME INHIBITION; HEALTH CARE ORGANIZATION; HUMAN; HUMAN CELL; MITOCHONDRIAL RESPIRATION; RESPIRATORY CHAIN;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; HYDRAZONES; IMIDAZOLES; MEMBRANE POTENTIALS; MITOCHONDRIA, LIVER; OXYGEN CONSUMPTION; QUINOLINES; RATS; STRUCTURE-ACTIVITY RELATIONSHIP; THIAZOLES;

EID: 20944432915     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm040888s     Document Type: Article

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