-
1
-
-
0031005627
-
Acute myeloid leukemia in the elderly: Assessment of multidrug resistance (MDR1) and cytogenetics distinguishes biologic subgroups with remarkably distinct responses to standard chemotherapy. A Southwest Oncology Group study
-
Leith CP, Kopecky KJ, Godwin J, et al. Acute myeloid leukemia in the elderly: assessment of multidrug resistance (MDR1) and cytogenetics distinguishes biologic subgroups with remarkably distinct responses to standard chemotherapy. A Southwest Oncology Group study. Blood. 1997;89:3323-3329.
-
(1997)
Blood
, vol.89
, pp. 3323-3329
-
-
Leith, C.P.1
Kopecky, K.J.2
Godwin, J.3
-
2
-
-
0032188805
-
The importance of diagnostic cytogenetics on outcome in AML: Analysis of 1612 patients entered into the MRC AML 10 trial
-
The Medical Research Council Adult and Children's Leukaemia Working Parties
-
Grimwade D, Walker H, Oliver F, et al. The importance of diagnostic cytogenetics on outcome in AML: analysis of 1612 patients entered into the MRC AML 10 trial. The Medical Research Council Adult and Children's Leukaemia Working Parties. Blood. 1998;92:2322-2333.
-
(1998)
Blood
, vol.92
, pp. 2322-2333
-
-
Grimwade, D.1
Walker, H.2
Oliver, F.3
-
3
-
-
0032413898
-
Multidrug resistance in leukemia
-
Leith C. Multidrug resistance in leukemia. Curr Opin Hematol. 1998;5:287-291.
-
(1998)
Curr Opin Hematol
, vol.5
, pp. 287-291
-
-
Leith, C.1
-
4
-
-
0030916669
-
The proto-oncogene bcl-2 and its role in regulating apoptosis
-
Kroemer G. The proto-oncogene bcl-2 and its role in regulating apoptosis. Nat Med. 1997;3:614-620.
-
(1997)
Nat Med
, vol.3
, pp. 614-620
-
-
Kroemer, G.1
-
5
-
-
0032409781
-
Bcl-2 family proteins
-
Reed JC. Bcl-2 family proteins. Oncogene. 1998;17:3225-3236.
-
(1998)
Oncogene
, vol.17
, pp. 3225-3236
-
-
Reed, J.C.1
-
6
-
-
0028910558
-
Inhibition of bcl-2 with antisense oligonucleotides induces apoptosis and increases the sensitivity of AML blasts to Ara-C
-
Keith FJ, Bradbury DA, Zhu Y-M, Russell NH. Inhibition of bcl-2 with antisense oligonucleotides induces apoptosis and increases the sensitivity of AML blasts to Ara-C. Leukemia. 1995;9:131-138.
-
(1995)
Leukemia
, vol.9
, pp. 131-138
-
-
Keith, F.J.1
Bradbury, D.A.2
Zhu, Y.-M.3
Russell, N.H.4
-
7
-
-
0034660068
-
Liposomal Bcl-2 antisense oligonucleotides enhance proliferation, sensitize acute myeloid leukemia to cytosine-arabinoside, and induce apoptosis independent of other antiapoptotic proteins
-
Konopleva M, Tari AM, Estrov Z, et al. Liposomal Bcl-2 antisense oligonucleotides enhance proliferation, sensitize acute myeloid leukemia to cytosine-arabinoside, and induce apoptosis independent of other antiapoptotic proteins. Blood. 2000;95:3929-3938.
-
(2000)
Blood
, vol.95
, pp. 3929-3938
-
-
Konopleva, M.1
Tari, A.M.2
Estrov, Z.3
-
8
-
-
0031436915
-
High bcl-2 expression in acute myeloid leukemia cells correlates with CD34 positivity and complete remission rate
-
Lauria F, Raspadori D, Rondelli D, et al. High bcl-2 expression in acute myeloid leukemia cells correlates with CD34 positivity and complete remission rate. Leukemia. 1997;11:2075-2078.
-
(1997)
Leukemia
, vol.11
, pp. 2075-2078
-
-
Lauria, F.1
Raspadori, D.2
Rondelli, D.3
-
9
-
-
0029111391
-
Bcl-2 protein expression in normal human bone marrow precursors and in acute myelogenous leukaemia
-
Porwitt-MacDonald A, Ivory K, Wilkinson S, Wheatley K, Wong L, Janossy G. Bcl-2 protein expression in normal human bone marrow precursors and in acute myelogenous leukaemia. Leukaemia. 1995;9:1191-1198.
-
(1995)
Leukaemia
, vol.9
, pp. 1191-1198
-
-
Porwitt-MacDonald, A.1
Ivory, K.2
Wilkinson, S.3
Wheatley, K.4
Wong, L.5
Janossy, G.6
-
10
-
-
0030770522
-
Five putative drug resistance parameters (MDR1/P-glycoprotein, MDR-associated protein, glutathione-S-transferase, bcl-2 and topoisomerase II α) in 57 newly diagnosed acute myeloid leukaemias
-
Lohri A, van Hille B, Bacchi M, et al. Five putative drug resistance parameters (MDR1/P-glycoprotein, MDR-associated protein, glutathione-S-transferase, bcl-2 and topoisomerase II α) in 57 newly diagnosed acute myeloid leukaemias. Eur J Haematol. 1997;59:206-215.
-
(1997)
Eur J Haematol
, vol.59
, pp. 206-215
-
-
Lohri, A.1
Van Hille, B.2
Bacchi, M.3
-
11
-
-
4244186406
-
The role of Bcl-2 apoptosis regulating genes in acute myeloid leukemia (AML)
-
Andreeff M, Zhao S, Konopleva M, et al. The role of Bcl-2 apoptosis regulating genes in acute myeloid leukemia (AML). Blood. 1997;90:66a.
-
(1997)
Blood
, vol.90
-
-
Andreeff, M.1
Zhao, S.2
Konopleva, M.3
-
12
-
-
0032006805
-
Elevated expression of the apoptotic regulator Mcl-1 at the time of leukemic relapse
-
Kaufmann SH, Karp JE, Svingen PA, et al. Elevated expression of the apoptotic regulator Mcl-1 at the time of leukemic relapse. Blood. 1998;91:991-1000.
-
(1998)
Blood
, vol.91
, pp. 991-1000
-
-
Kaufmann, S.H.1
Karp, J.E.2
Svingen, P.A.3
-
13
-
-
0032721858
-
Expression of Bcl-2-related genes in normal and AML progenitors: Changes induced by chemotherapy and retinoic acid
-
Andreeff M, Jiang S, Zhang X, et al. Expression of Bcl-2-related genes in normal and AML progenitors: changes induced by chemotherapy and retinoic acid. Leukemia. 1999;13:1881-1892.
-
(1999)
Leukemia
, vol.13
, pp. 1881-1892
-
-
Andreeff, M.1
Jiang, S.2
Zhang, X.3
-
14
-
-
0033088957
-
Review: The role of glutathione in the regulation of apoptosis
-
Hall AG. Review: the role of glutathione in the regulation of apoptosis. Eur J Clin Invest. 1999;29:238-245.
-
(1999)
Eur J Clin Invest
, vol.29
, pp. 238-245
-
-
Hall, A.G.1
-
16
-
-
0026725084
-
Expression of glutathione transferase π as a predictor for treatment results at different stages of acute nonlymphoblastic leukemia
-
Tidefelt U, Elmhorn-Rosenborg A, Paul C, Hao X, Mannervik B, Eriksson L. Expression of glutathione transferase π as a predictor for treatment results at different stages of acute nonlymphoblastic leukemia. Cancer Res. 1992;52:3281-3285.
-
(1992)
Cancer Res
, vol.52
, pp. 3281-3285
-
-
Tidefelt, U.1
Elmhorn-Rosenborg, A.2
Paul, C.3
Hao, X.4
Mannervik, B.5
Eriksson, L.6
-
17
-
-
0028903502
-
Thiol-mediated redox regulation of apoptosis: Possible roles of cellular thiols other than glutathione in T cell apoptosis
-
Sato N, Iwata S, Nakamura K, Hori T, Mori K, Yodoi J. Thiol-mediated redox regulation of apoptosis: possible roles of cellular thiols other than glutathione in T cell apoptosis. J Immunol. 1995;154:3194-3203.
-
(1995)
J Immunol
, vol.154
, pp. 3194-3203
-
-
Sato, N.1
Iwata, S.2
Nakamura, K.3
Hori, T.4
Mori, K.5
Yodoi, J.6
-
18
-
-
0030956591
-
Possible roles of an adult T-cell leukemia (ATL)-derived factor/thioredoxin in the drug resistance of ATL to Adriamycin
-
Wang J, Kobayashi M, Sakurada K, Imamura M, Moriuchi T, Hosokawa M. Possible roles of an adult T-cell leukemia (ATL)-derived factor/thioredoxin in the drug resistance of ATL to Adriamycin. Blood. 1997;89:2480-2487.
-
(1997)
Blood
, vol.89
, pp. 2480-2487
-
-
Wang, J.1
Kobayashi, M.2
Sakurada, K.3
Imamura, M.4
Moriuchi, T.5
Hosokawa, M.6
-
19
-
-
0032080283
-
Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1
-
Saitoh M, Nishitoh H, Fujii M, etal. Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1. EMBO J. 1998;17:2596-2606.
-
(1998)
EMBO J
, vol.17
, pp. 2596-2606
-
-
Saitoh, M.1
Nishitoh, H.2
Fujii, M.3
-
20
-
-
0028172868
-
P53 mutations are associated with resistance to chemotherapy and short survival in hematologic malignancies
-
Wattel E, Preudhomme C, Hecquet B, et al. P53 mutations are associated with resistance to chemotherapy and short survival in hematologic malignancies. Blood. 1994;84:3148-3157.
-
(1994)
Blood
, vol.84
, pp. 3148-3157
-
-
Wattel, E.1
Preudhomme, C.2
Hecquet, B.3
-
21
-
-
9844222496
-
p53-induced apoptosis in the human T-ALL cell line CCRF-CEM
-
Geley S, Hartmann BL, Hattmannstorfer R, et al. p53-induced apoptosis in the human T-ALL cell line CCRF-CEM. Oncogene. 1997;15:2429-2437.
-
(1997)
Oncogene
, vol.15
, pp. 2429-2437
-
-
Geley, S.1
Hartmann, B.L.2
Hattmannstorfer, R.3
-
22
-
-
0032191655
-
Inhibition of p53-dependent apoptosis by the KIT tyrosine kinase: Regulation of mitochondrial permeability transition and reactive oxygen species generation
-
Lee JM. Inhibition of p53-dependent apoptosis by the KIT tyrosine kinase: regulation of mitochondrial permeability transition and reactive oxygen species generation. Oncogene. 1998;17:1653-1662.
-
(1998)
Oncogene
, vol.17
, pp. 1653-1662
-
-
Lee, J.M.1
-
23
-
-
0030930366
-
A model for p53-induced apoptosis
-
Polyak K, Xia Y, Zweier JL, Kinzler KW, Vogelstein B. A model for p53-induced apoptosis. Nature. 1997;389:300-305.
-
(1997)
Nature
, vol.389
, pp. 300-305
-
-
Polyak, K.1
Xia, Y.2
Zweier, J.L.3
Kinzler, K.W.4
Vogelstein, B.5
-
24
-
-
0032552946
-
Contrasting patterns of regulation of the antioxidant selenoproteins, thioredoxin reductase, and glutathione peroxidase in cancer cells
-
Gladyshev VN, Factor VM, Housseau F, Hatfield DL. Contrasting patterns of regulation of the antioxidant selenoproteins, thioredoxin reductase, and glutathione peroxidase in cancer cells. Biochem Biophys Res Commun. 1998;251:488-493.
-
(1998)
Biochem Biophys Res Commun
, vol.251
, pp. 488-493
-
-
Gladyshev, V.N.1
Factor, V.M.2
Housseau, F.3
Hatfield, D.L.4
-
25
-
-
0032535308
-
Transcriptional suppression of multidrug resistance-associated protein (MRP) gene expression by wild-type p53
-
Wang Q, Beck WT. Transcriptional suppression of multidrug resistance-associated protein (MRP) gene expression by wild-type p53. Cancer Res. 1998;58:5762-5769.
-
(1998)
Cancer Res
, vol.58
, pp. 5762-5769
-
-
Wang, Q.1
Beck, W.T.2
-
26
-
-
0031974274
-
Mitochondria in chemotherapy-induced apoptosis: A prospective novel target of cancer therapy
-
Decaudin D, Matzo I, Brenner C, Kroemer G. Mitochondria in chemotherapy-induced apoptosis: a prospective novel target of cancer therapy. Int J Oncol. 1998;12:141-152.
-
(1998)
Int J Oncol
, vol.12
, pp. 141-152
-
-
Decaudin, D.1
Matzo, I.2
Brenner, C.3
Kroemer, G.4
-
27
-
-
0029116916
-
The mitochondrial permeability transition
-
Zoratti M, Szabo I. The mitochondrial permeability transition. Biochim Biophys Acta. 1995;1241:139-176.
-
(1995)
Biochim Biophys Acta
, vol.1241
, pp. 139-176
-
-
Zoratti, M.1
Szabo, I.2
-
28
-
-
0029862706
-
Mitochondrial control of nuclear apoptosis
-
Zamzami N, Susin SA, Marchetti P, et al. Mitochondrial control of nuclear apoptosis. J Exp Med. 1996;183:1533-1544.
-
(1996)
J Exp Med
, vol.183
, pp. 1533-1544
-
-
Zamzami, N.1
Susin, S.A.2
Marchetti, P.3
-
29
-
-
0030773136
-
Implication of mitochondria in apoptosis
-
Petit PX, Zamzami N, Vayssiere JL, Mignotte B, Kroemer G, Castedo M. Implication of mitochondria in apoptosis. Mol Cell Biochem. 1997;174:185-188.
-
(1997)
Mol Cell Biochem
, vol.174
, pp. 185-188
-
-
Petit, P.X.1
Zamzami, N.2
Vayssiere, J.L.3
Mignotte, B.4
Kroemer, G.5
Castedo, M.6
-
30
-
-
0028019746
-
Cell-free apoptosis in xenopus egg extracts: Inhibition by bcl-2 and requirement for an organelle fraction enriched in mitochondria
-
Newmeyer D, Farschon D, Reed J. Cell-free apoptosis in xenopus egg extracts: inhibition by bcl-2 and requirement for an organelle fraction enriched in mitochondria. Cell. 1994;79:353-364.
-
(1994)
Cell
, vol.79
, pp. 353-364
-
-
Newmeyer, D.1
Farschon, D.2
Reed, J.3
-
31
-
-
0001425438
-
The cell biology of apoptosis: Evidence for the implication of mitochondria
-
Susin S, Zamzami N, Kroemer K. The cell biology of apoptosis: evidence for the implication of mitochondria. Apoptosis. 1996;1:231-242.
-
(1996)
Apoptosis
, vol.1
, pp. 231-242
-
-
Susin, S.1
Zamzami, N.2
Kroemer, K.3
-
32
-
-
0027433653
-
Physiological effectors modify voltage sensing by the cyclosporin A-sensitive permeability transition pore of mitochondria
-
Petronilli V, Cola C, Massari S, Colonna R, Bernardi P. Physiological effectors modify voltage sensing by the cyclosporin A-sensitive permeability transition pore of mitochondria. J Biol Chem. 1993;268:21939-21945.
-
(1993)
J Biol Chem
, vol.268
, pp. 21939-21945
-
-
Petronilli, V.1
Cola, C.2
Massari, S.3
Colonna, R.4
Bernardi, P.5
-
33
-
-
0028239794
-
The voltage sensor of the mitochondrial permeability transition pore is tuned by the oxidation-reduction state of vicinal thiols: Increase of the gating potential by oxidants and its reversal by reducing agents
-
Petronilli V, Costantini P, Scorrano L, Colonna R, Passamonti S, Bernardi P. The voltage sensor of the mitochondrial permeability transition pore is tuned by the oxidation-reduction state of vicinal thiols: increase of the gating potential by oxidants and its reversal by reducing agents. J Biol Chem. 1994;269:16638-16642.
-
(1994)
J Biol Chem
, vol.269
, pp. 16638-16642
-
-
Petronilli, V.1
Costantini, P.2
Scorrano, L.3
Colonna, R.4
Passamonti, S.5
Bernardi, P.6
-
34
-
-
0028938858
-
Selective inhibition of the mitochondrial permeability transition pore at the oxidation-reduction sensitive dithiol by monobromobimane
-
Costantini P, Chernyak BV, Petronilli V, Bernardi P. Selective inhibition of the mitochondrial permeability transition pore at the oxidation-reduction sensitive dithiol by monobromobimane. FEBS Lett. 1995;362:239-242.
-
(1995)
FEBS Lett
, vol.362
, pp. 239-242
-
-
Costantini, P.1
Chernyak, B.V.2
Petronilli, V.3
Bernardi, P.4
-
35
-
-
9544246860
-
Mitochondrial permeability transition is a central coordinating event of apoptosis
-
Marchetti P, Castedo M, Susin SA, et al. Mitochondrial permeability transition is a central coordinating event of apoptosis. J Exp Med. 1996;184:1155-1160.
-
(1996)
J Exp Med
, vol.184
, pp. 1155-1160
-
-
Marchetti, P.1
Castedo, M.2
Susin, S.A.3
-
36
-
-
0029906828
-
Bax-induced cell-death may not require interleukin 1-beta-converting enzyme-like proteases
-
Xiang JL, Chao DT, Korsmeyer SJ. Bax-induced cell-death may not require interleukin 1-beta-converting enzyme-like proteases. Proc Natl Acad Sci U S A. 1996;93:14559-14563.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 14559-14563
-
-
Xiang, J.L.1
Chao, D.T.2
Korsmeyer, S.J.3
-
37
-
-
0029950290
-
Bcl-2 inhibits the mitochondrial release of an apoptogenic protease
-
Susin S, Zamzami N, Castedo M, et al. Bcl-2 inhibits the mitochondrial release of an apoptogenic protease. J Exp Med. 1996;184:1331-1341.
-
(1996)
J Exp Med
, vol.184
, pp. 1331-1341
-
-
Susin, S.1
Zamzami, N.2
Castedo, M.3
-
38
-
-
0032566649
-
Bax and adenine nucleotide translocator cooperate in the mitochondrial control of apoptosis
-
Marzo I, Brenner C, Zamzami N, et al. Bax and adenine nucleotide translocator cooperate in the mitochondrial control of apoptosis. Science. 1998;281:2027-2031.
-
(1998)
Science
, vol.281
, pp. 2027-2031
-
-
Marzo, I.1
Brenner, C.2
Zamzami, N.3
-
39
-
-
0032539673
-
Bcl-2 prevents apoptotic mitochondrial dysfunction by regulating proton flux
-
Shimizu S, Eguchi Y, Kamiike W, et al. Bcl-2 prevents apoptotic mitochondrial dysfunction by regulating proton flux. Proc Natl Acad Sci U S A. 1998;95:1455-1459.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 1455-1459
-
-
Shimizu, S.1
Eguchi, Y.2
Kamiike, W.3
-
40
-
-
0033519705
-
Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC
-
Shimizu S, Narita M, Tsujimoto Y. Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC. Nature. 1999;399:483-487.
-
(1999)
Nature
, vol.399
, pp. 483-487
-
-
Shimizu, S.1
Narita, M.2
Tsujimoto, Y.3
-
41
-
-
0343090208
-
Slow fluorescent indicators of membrane potential: A survey of different approaches to probe response analysis
-
Plasek J, Sigler K. Slow fluorescent indicators of membrane potential: a survey of different approaches to probe response analysis. J Photochem Photobiol B. 1996;33:101-124.
-
(1996)
J Photochem Photobiol B
, vol.33
, pp. 101-124
-
-
Plasek, J.1
Sigler, K.2
-
42
-
-
0030837332
-
L is heterogeneously expressed by acute myeloblastic leukemia cells and is associated with autonomous growth in vitro and with p-glycoprotein expression
-
L is heterogeneously expressed by acute myeloblastic leukemia cells and is associated with autonomous growth in vitro and with p-glycoprotein expression. Leukemia. 1997;11:945-949.
-
(1997)
Leukemia
, vol.11
, pp. 945-949
-
-
Pallis, M.1
Zhu, Y.M.2
Russell, N.H.3
-
43
-
-
0032620223
-
Reproducible flow cytometric methodology for measuring multidrug resistance in leukaemic blasts
-
Pallis M, Turzanski J, Langabeer S, Russell NH. Reproducible flow cytometric methodology for measuring multidrug resistance in leukaemic blasts. Adv Exp Med Biol. 1999;457:77-88.
-
(1999)
Adv Exp Med Biol
, vol.457
, pp. 77-88
-
-
Pallis, M.1
Turzanski, J.2
Langabeer, S.3
Russell, N.H.4
-
44
-
-
0029866409
-
The use of 7-amino actinomycin D in identifying apoptosis: Simplicity of use and broad spectrum of application compared with other techniques
-
Philpott N, Turner A, Scopes J, et al. The use of 7-amino actinomycin D in identifying apoptosis: simplicity of use and broad spectrum of application compared with other techniques. Blood. 1996;87:2244-2251.
-
(1996)
Blood
, vol.87
, pp. 2244-2251
-
-
Philpott, N.1
Turner, A.2
Scopes, J.3
-
45
-
-
0034192163
-
P-glycoprotein plays a drug-efflux-independent role in augmenting cell survival in acute myeloblastic leukemia and is associated with modulation of a sphingomyelinceramide apoptotic pathway
-
Pallis M, Russell N. P-glycoprotein plays a drug-efflux-independent role in augmenting cell survival in acute myeloblastic leukemia and is associated with modulation of a sphingomyelinceramide apoptotic pathway. Blood. 2000;95:2897-2904.
-
(2000)
Blood
, vol.95
, pp. 2897-2904
-
-
Pallis, M.1
Russell, N.2
-
46
-
-
0033566355
-
Microsatellite instability and p53 mutations are associated with abnormal expression of the MSH2 gene in adult acute leukemia
-
Zhu YM, Das-Gupta EP, Russell NH. Microsatellite instability and p53 mutations are associated with abnormal expression of the MSH2 gene in adult acute leukemia. Blood. 1999;94:733-740.
-
(1999)
Blood
, vol.94
, pp. 733-740
-
-
Zhu, Y.M.1
Das-Gupta, E.P.2
Russell, N.H.3
-
47
-
-
0031013150
-
Redox regulation of apoptosis: Impact of thiol oxidation status on mitochondrial function
-
Marchetti P, Decaudin D, Macho A, et al. Redox regulation of apoptosis: impact of thiol oxidation status on mitochondrial function. Eur J Immunol. 1997;27:289-296.
-
(1997)
Eur J Immunol
, vol.27
, pp. 289-296
-
-
Marchetti, P.1
Decaudin, D.2
Macho, A.3
-
48
-
-
0030612749
-
3 or rhodamine 123, is a reliable fluorescent probe to assess δ ψ changes in intact cells: Implications for studies on mitochondrial functionality during apoptosis
-
3 or rhodamine 123, is a reliable fluorescent probe to assess δ ψ changes in intact cells: implications for studies on mitochondrial functionality during apoptosis. FEBS Lett. 1997;411:77-82.
-
(1997)
FEBS Lett
, vol.411
, pp. 77-82
-
-
Salvioli, S.1
Ardizzoni, A.2
Franceschi, C.3
Cossarizza, A.4
-
50
-
-
0027185541
-
Autonomous growth of blast cells is associated with reduced survival in acute myeloblastic leukemia
-
Hunter AE, Rogers SY, Roberts IA, Barrett AJ, Russell N. Autonomous growth of blast cells is associated with reduced survival in acute myeloblastic leukemia. Blood. 1993;82:899-903.
-
(1993)
Blood
, vol.82
, pp. 899-903
-
-
Hunter, A.E.1
Rogers, S.Y.2
Roberts, I.A.3
Barrett, A.J.4
Russell, N.5
-
51
-
-
0023578443
-
The effects of three recombinant growth factors, IL-3, GM-CSF, and G-CSF, on the blast cells of acute myeloblastic leukemia maintained in short-term suspension culture
-
Miyauchi J, Kelleher CA, Yang YC, et al. The effects of three recombinant growth factors, IL-3, GM-CSF, and G-CSF, on the blast cells of acute myeloblastic leukemia maintained in short-term suspension culture. Blood. 1987;70:657-663.
-
(1987)
Blood
, vol.70
, pp. 657-663
-
-
Miyauchi, J.1
Kelleher, C.A.2
Yang, Y.C.3
-
52
-
-
0031032294
-
Bcl-2 and Bcl-XL antagonize the mitochondrial dysfunction preceding nuclear apoptosis induced by chemotherapeutic agents
-
Decaudin D, Geley S, Hirsch T, et al. Bcl-2 and Bcl-XL antagonize the mitochondrial dysfunction preceding nuclear apoptosis induced by chemotherapeutic agents. Cancer Res. 1997;57:62-67.
-
(1997)
Cancer Res
, vol.57
, pp. 62-67
-
-
Decaudin, D.1
Geley, S.2
Hirsch, T.3
-
54
-
-
0033597221
-
Transcriptional activation of the human glutathione peroxidase promoter by p53
-
Tan M, Li S, Swaroop M, Guan K, Oberley LW, Sun Y. Transcriptional activation of the human glutathione peroxidase promoter by p53. J Biol Chem. 1999;274:12061-12066.
-
(1999)
J Biol Chem
, vol.274
, pp. 12061-12066
-
-
Tan, M.1
Li, S.2
Swaroop, M.3
Guan, K.4
Oberley, L.W.5
Sun, Y.6
-
55
-
-
0033974414
-
Comments on: Multidrug resistance-associated protein (MRP) expression is correlated with expression of aberrant p53 protein in colorectal cancer: Mutant p53 and high expression of MRP are associated in acute myeloblastic leukaemia
-
Turzanski J, Pallis M, Russell N. Comments on: multidrug resistance-associated protein (MRP) expression is correlated with expression of aberrant p53 protein in colorectal cancer: mutant p53 and high expression of MRP are associated in acute myeloblastic leukaemia [letter]. Eur J Cancer. 2000;36:270-272.
-
(2000)
Eur J Cancer
, vol.36
, pp. 270-272
-
-
Turzanski, J.1
Pallis, M.2
Russell, N.3
-
56
-
-
0033567429
-
New insights into the biology and pharmacology of the multidrug resistance protein (MRP) from gene knockout models
-
Rappa G, Finch RA, Sartorelli AC, Lorico A. New insights into the biology and pharmacology of the multidrug resistance protein (MRP) from gene knockout models. Biochem Pharmacol. 1999;58:557-562.
-
(1999)
Biochem Pharmacol
, vol.58
, pp. 557-562
-
-
Rappa, G.1
Finch, R.A.2
Sartorelli, A.C.3
Lorico, A.4
-
57
-
-
0032605942
-
Multidrug resistance protein MRP1, glutathione, and related enzymes: Their importance in acute myeloid leukemia
-
van der Kolk DM, Vellenga E, Muller M, de Vries EG. Multidrug resistance protein MRP1, glutathione, and related enzymes: their importance in acute myeloid leukemia. Adv Exp Med Biol. 1999;457:187-198.
-
(1999)
Adv Exp Med Biol
, vol.457
, pp. 187-198
-
-
Van der Kolk, D.M.1
Vellenga, E.2
Muller, M.3
De Vries, E.G.4
-
58
-
-
0030038762
-
The mitochondrial permeability transition pore is modulated by oxidative agents through both pyridine nucleotides and glutathione at two separate sites
-
Chernyak BV, Bernardi P. The mitochondrial permeability transition pore is modulated by oxidative agents through both pyridine nucleotides and glutathione at two separate sites. Eur J Biochem. 1996;238:623-630.
-
(1996)
Eur J Biochem
, vol.238
, pp. 623-630
-
-
Chernyak, B.V.1
Bernardi, P.2
-
59
-
-
0030694267
-
Redox regulation of the mitochondrial permeability transition pore
-
Chernyak BV. Redox regulation of the mitochondrial permeability transition pore. Biosci Rep. 1997;17:293-302.
-
(1997)
Biosci Rep
, vol.17
, pp. 293-302
-
-
Chernyak, B.V.1
-
60
-
-
0029863399
-
Modulation of the mitochondrial permeability transition pore by pyridine nucleotides and dithiol oxidation at two separate sites
-
Costantini P, Chernyak BV, Petronilli V, Bernardi P. Modulation of the mitochondrial permeability transition pore by pyridine nucleotides and dithiol oxidation at two separate sites. J Biol Chem. 1996;271:6746-6751.
-
(1996)
J Biol Chem
, vol.271
, pp. 6746-6751
-
-
Costantini, P.1
Chernyak, B.V.2
Petronilli, V.3
Bernardi, P.4
-
61
-
-
0029033862
-
Mitochondrial changes associated with glutathione deficiency
-
Meister A. Mitochondrial changes associated with glutathione deficiency. Biochim Biophys Acta. 1995;1271:35-42.
-
(1995)
Biochim Biophys Acta
, vol.1271
, pp. 35-42
-
-
Meister, A.1
-
62
-
-
0019995368
-
The use of drugs which deplete intracellular glutathione in hypoxic cell radiosensitization
-
Bump EA, Yu NY, Brown JM. The use of drugs which deplete intracellular glutathione in hypoxic cell radiosensitization. Int J Radiat Oncol Biol Phys. 1982;8:439-442.
-
(1982)
Int J Radiat Oncol Biol Phys
, vol.8
, pp. 439-442
-
-
Bump, E.A.1
Yu, N.Y.2
Brown, J.M.3
-
63
-
-
0030754701
-
Resistance to radiation-induced apoptosis in Bcl-2-expressing cells is reversed by depleting cellular thiols
-
Mirkovic N, Voehringer DW, Story MD, McConkey DJ, McDonnell TJ, Meyn RE. Resistance to radiation-induced apoptosis in Bcl-2-expressing cells is reversed by depleting cellular thiols. Oncogene. 1997;15:1461-1470.
-
(1997)
Oncogene
, vol.15
, pp. 1461-1470
-
-
Mirkovic, N.1
Voehringer, D.W.2
Story, M.D.3
McConkey, D.J.4
McDonnell, T.J.5
Meyn, R.E.6
-
64
-
-
0027990215
-
Apoptosis or necrosis: Intracellular levels of glutathione influence mode of cell death
-
Fernandes RS, Cotter TG. Apoptosis or necrosis: intracellular levels of glutathione influence mode of cell death. Biochem Pharmacol. 1994;48:675-681.
-
(1994)
Biochem Pharmacol
, vol.48
, pp. 675-681
-
-
Fernandes, R.S.1
Cotter, T.G.2
-
65
-
-
0032534748
-
Redox regulation of caspase-3(-like) protease activity: Regulatory roles of thioredoxin and cytochrome c
-
Ueda S, Nakamura H, Masutani H, et al. Redox regulation of caspase-3(-like) protease activity: regulatory roles of thioredoxin and cytochrome c. J Immunol. 1998;161:6689-6695.
-
(1998)
J Immunol
, vol.161
, pp. 6689-6695
-
-
Ueda, S.1
Nakamura, H.2
Masutani, H.3
-
66
-
-
0031987277
-
Regulation of p53 downstream genes
-
El-Deiry WS. Regulation of p53 downstream genes. Semin Cancer Biol. 1998;8:345-357.
-
(1998)
Semin Cancer Biol
, vol.8
, pp. 345-357
-
-
El-Deiry, W.S.1
-
67
-
-
0031869758
-
Predicting response to cancer chemotherapy: The role of p53
-
Weller M. Predicting response to cancer chemotherapy: the role of p53. Cell Tissue Res. 1998;292:435-445.
-
(1998)
Cell Tissue Res
, vol.292
, pp. 435-445
-
-
Weller, M.1
-
68
-
-
0033229866
-
P53 regulates mitochondrial membrane potential through reactive oxygen species and induces cytochrome c-independent apoptosis blocked by Bcl-2
-
Li PF, Dietz R, von Harsdorf R. P53 regulates mitochondrial membrane potential through reactive oxygen species and induces cytochrome c-independent apoptosis blocked by Bcl-2. EMBO J. 1999;18:6027-6036.
-
(1999)
EMBO J
, vol.18
, pp. 6027-6036
-
-
Li, P.F.1
Dietz, R.2
Von Harsdorf, R.3
-
69
-
-
0029958381
-
Reactive oxygen species are down-stream mediators of p53-dependent apoptosis
-
Johnson TM, Yu ZX, Ferrans VJ, Lowenstein RA, Finkel T. Reactive oxygen species are down-stream mediators of p53-dependent apoptosis. Proc Natl Acad Sci U S A. 1996;93:11848-11852.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 11848-11852
-
-
Johnson, T.M.1
Yu, Z.X.2
Ferrans, V.J.3
Lowenstein, R.A.4
Finkel, T.5
-
70
-
-
0031013623
-
Oxidative stress, thiol reagents, and membrane potential modulate the mitochondrial permeability transition by affecting nucleotide binding to the adenine nucleotide translocase
-
Halestrap AP, Woodfield KY, Connern CP. Oxidative stress, thiol reagents, and membrane potential modulate the mitochondrial permeability transition by affecting nucleotide binding to the adenine nucleotide translocase. J Biol Chem. 1997;272:3346-3354.
-
(1997)
J Biol Chem
, vol.272
, pp. 3346-3354
-
-
Halestrap, A.P.1
Woodfield, K.Y.2
Connern, C.P.3
-
71
-
-
0034642510
-
Oxidation of a critical thiol residue of the adenine nucleotide translocator enforces Bcl-2-independent permeability transition pore opening and apoptosis
-
Costantini P, Belzacq AS, Vieira HL, et al. Oxidation of a critical thiol residue of the adenine nucleotide translocator enforces Bcl-2-independent permeability transition pore opening and apoptosis. Oncogene. 2000;19:307-314.
-
(2000)
Oncogene
, vol.19
, pp. 307-314
-
-
Costantini, P.1
Belzacq, A.S.2
Vieira, H.L.3
-
72
-
-
0029983059
-
Inhibitors of permeability transition interfere with the disruption of the mitochondrial transmembrane potential during apoptosis
-
Zamzami N, Marchetti P, Castedo M, et al. Inhibitors of permeability transition interfere with the disruption of the mitochondrial transmembrane potential during apoptosis. FEBS Lett. 1996;384:53-57.
-
(1996)
FEBS Lett
, vol.384
, pp. 53-57
-
-
Zamzami, N.1
Marchetti, P.2
Castedo, M.3
-
73
-
-
0031464448
-
Bcl-2 family proteins: Regulators of apoptosis and chemoresistance in hematologic malignancies
-
Reed JC. Bcl-2 family proteins: regulators of apoptosis and chemoresistance in hematologic malignancies. Semin Hematol. 1997;34:9-19.
-
(1997)
Semin Hematol
, vol.34
, pp. 9-19
-
-
Reed, J.C.1
-
74
-
-
0027485461
-
Bcl-2 functions in an antioxidant pathway to prevent apoptosis
-
Hockenbery DM, Oltvai ZN, Yin XM, Milliman CL, Korsmeyer SJ. Bcl-2 functions in an antioxidant pathway to prevent apoptosis. Cell. 1993;75:241-251.
-
(1993)
Cell
, vol.75
, pp. 241-251
-
-
Hockenbery, D.M.1
Oltvai, Z.N.2
Yin, X.M.3
Milliman, C.L.4
Korsmeyer, S.J.5
-
75
-
-
0032567877
-
The thiol crosslinking agent diamide overcomes the apoptosis-inhibitory effect of Bcl-2 by enforcing mitochondrial permeability transition
-
Zamzami N, Marzo I, Susin SA, et al. The thiol crosslinking agent diamide overcomes the apoptosis-inhibitory effect of Bcl-2 by enforcing mitochondrial permeability transition. Oncogene. 1998;16:1055-1063.
-
(1998)
Oncogene
, vol.16
, pp. 1055-1063
-
-
Zamzami, N.1
Marzo, I.2
Susin, S.A.3
-
76
-
-
15844416284
-
Coordinated induction of MRP/GS-X pump and γ-glutamylcysteine synthetase by heavy metals in human leukemia cells
-
Ishikawa T, Bao JJ, Yamane Y, et al. Coordinated induction of MRP/GS-X pump and γ-glutamylcysteine synthetase by heavy metals in human leukemia cells. J Biol Chem. 1996;271:14981-14988.
-
(1996)
J Biol Chem
, vol.271
, pp. 14981-14988
-
-
Ishikawa, T.1
Bao, J.J.2
Yamane, Y.3
-
77
-
-
0032031395
-
Frequent coexpression of MRP/GS-X pump and γ-glutamylcysteine synthetase mRNA in drug-resistant cells, untreated tumor cells, and normal mouse tissues
-
Kuo MT, Bao J, Furuichi M, et al. Frequent coexpression of MRP/GS-X pump and γ-glutamylcysteine synthetase mRNA in drug-resistant cells, untreated tumor cells, and normal mouse tissues. Biochem Pharmacol. 1998;55:605-615.
-
(1998)
Biochem Pharmacol
, vol.55
, pp. 605-615
-
-
Kuo, M.T.1
Bao, J.2
Furuichi, M.3
-
78
-
-
0028881958
-
Comparative quantitative expression of bcl-2 by normal and leukaemic myeloid cells
-
Bradbury DA, Russell NH. Comparative quantitative expression of bcl-2 by normal and leukaemic myeloid cells. Br J Haematol. 1995;91:374-379.
-
(1995)
Br J Haematol
, vol.91
, pp. 374-379
-
-
Bradbury, D.A.1
Russell, N.H.2
-
79
-
-
0032612963
-
Evidence for the involvement of the glutathione pathway in drug resistance in AML
-
Sargent JM, Williamson C, Hall AG, Elgie AW, Taylor CG. Evidence for the involvement of the glutathione pathway in drug resistance in AML. Adv Exp Med Biol. 1999;457:205-209.
-
(1999)
Adv Exp Med Biol
, vol.457
, pp. 205-209
-
-
Sargent, J.M.1
Williamson, C.2
Hall, A.G.3
Elgie, A.W.4
Taylor, C.G.5
|