Isolation and characterization of human anti-acetylcholine receptor monoclonal antibodies from transgenic mice expressing human immunoglobulin loci

European Journal of Immunology

Volumn 35, Issue 6, 2005, Pages 1960-1968

  Protopapadakis, Evdokia ^a   Kokla, Anna ^a   Tzartos, Socrates J ^a,b   Mamalaki, Avgi ^a  

^a HELLENIC PASTEUR INSTITUTE   (Greece)

^b UNIVERSITY OF PATRAS   (Greece)

Author keywords

Human acetylcholine receptor; Human monoclonal antibodies; Myasthenia gravis; Transgenic humanized mice

Indexed keywords

AUTOANTIBODY; CHOLINERGIC RECEPTOR; CHOLINERGIC RECEPTOR ANTIBODY; EPITOPE; IMMUNOGLOBULIN; IMMUNOGLOBULIN F(AB) FRAGMENT; IMMUNOGLOBULIN M ANTIBODY; MONOCLONAL ANTIBODY;

ALPHA CHAIN; ANIMAL CELL; ANIMAL EXPERIMENT; ANTIBODY ISOLATION; ANTIBODY RESPONSE; ANTIGENIC MODULATION; ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HYBRIDOMA; IMMUNIZATION; MOUSE; MOUSE STRAIN; MYASTHENIA GRAVIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTECTION; PROTEIN EXPRESSION; RADIOIMMUNOASSAY; TRANSGENIC MOUSE;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, MONOCLONAL; BASE SEQUENCE; BINDING, COMPETITIVE; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENES, IMMUNOGLOBULIN; HUMANS; IMMUNOGLOBULIN FAB FRAGMENTS; IMMUNOGLOBULIN VARIABLE REGION; MICE; MICE, TRANSGENIC; MOLECULAR SEQUENCE DATA; MYASTHENIA GRAVIS; RATS; RECEPTORS, CHOLINERGIC;

EID: 20844458150     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/eji.200526173     Document Type: Article

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