Reconstitution of conformationally dependent epitopes on the N-terminal extracellular domain of the human muscle acetylcholine receptor α subunit expressed in Escherichia coli: Implications for myasthenia gravis therapeutic approaches

International Immunology

Volumn 12, Issue 9, 2000, Pages 1255-1265

  Tsouloufis, T ^a   Mamalaki, A ^a   Remoundos, M ^a   Tzartos, S J ^a  

^a HELLENIC PASTEUR INSTITUTE   (Greece)

Author keywords

Acetylcholine receptor; Artificial chaperones; Conformationally dependent epitopes; Main immunogenic region; Myasthenia gravis; Renaturation

Indexed keywords

AUTOANTIBODY; AUTOANTIGEN; BUFFER; CHAPERONE; CHOLINERGIC RECEPTOR; CHOLINERGIC RECEPTOR ANTIBODY; CYCLODEXTRIN; DETERGENT; EPITOPE; GUANIDINE; MEMBRANE PROTEIN; MONOCLONAL ANTIBODY; MUSCLE PROTEIN; OLIGOMER; OLIGOSACCHARIDE; POLYPEPTIDE; PROTEIN SUBUNIT;

ALPHA CHAIN; AMINO TERMINAL SEQUENCE; ANTIGEN BINDING; ARTICLE; AUTOIMMUNE DISEASE; BETA CHAIN; CONTROLLED STUDY; ESCHERICHIA COLI; EXTRACELLULAR SPACE; HUMAN; IMMUNOGENICITY; MYASTHENIA GRAVIS; NONHUMAN; PATHOGENICITY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DENATURATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN PURIFICATION; PROTEIN STRUCTURE;

ANTIBODIES, MONOCLONAL; CLONING, MOLECULAR; CYCLODEXTRINS; DETERGENTS; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPITOPES; ESCHERICHIA COLI; HUMANS; MUSCLE, SKELETAL; MYASTHENIA GRAVIS; PEPTIDES; PROTEIN CONFORMATION; PROTEIN DENATURATION; RECEPTORS, CHOLINERGIC; RECOMBINANT PROTEINS;

EID: 0033842133     PISSN: 09538178     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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