Intrapulmonary and intramyocardial gene transfer in rhesus monkeys (Macaca mulatta): Safety and efficiency of HIV-1-derived lentiviral vectors for fetal gene delivery

Molecular Therapy

Volumn 12, Issue 1, 2005, Pages 87-98

  Tarantal, Alice F ^a,b   McDonald, Ruth J ^a,b   Jimenez, Daniel F ^a   Lee, Chang I ^a   O'Shea, Cristin E ^a   Leapley, Alyssa C ^a   Won, Rosa H ^a,b   Plopper, Charles G ^a,c   Lutzko, Carolyn ^d   Kohn, Donald B ^d  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d CHILDREN S HOSPITAL LOS ANGELES   (United States)

Author keywords

EGFP; Fetus; Heart; HIV 1 derived lentivirus; Infant; Lung; Monkey

Indexed keywords

ENHANCED GREEN FLUORESCENT PROTEIN; LENTIVIRUS VECTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOMEGALOVIRUS; ECHOCARDIOGRAPHY; FETUS; FETUS ECHOGRAPHY; FLUORESCENCE; GENE EXPRESSION; GENE TARGETING; GESTATION PERIOD; HEART DEVELOPMENT; HEART MUSCLE; HUMAN IMMUNODEFICIENCY VIRUS 1; LUNG FUNCTION TEST; LUNG PARENCHYMA; NONHUMAN; PERICARDIUM; POLYMERASE CHAIN REACTION; POSTNATAL GROWTH; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; RHESUS MONKEY; TARGET ORGAN; VIRAL GENE DELIVERY SYSTEM;

ANIMALS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FETAL WEIGHT; FETUS; FLUORESCENT ANTIBODY TECHNIQUE, DIRECT; GENE TRANSFER TECHNIQUES; GENES, REPORTER; GENETIC VECTORS; HIV-1; LUNG; MACACA MULATTA; MYOCARDIUM; POLYMERASE CHAIN REACTION; PREGNANCY;

ANIMALIA; CUCUMBER MOSAIC VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; LENTIVIRUS; MACACA MULATTA;

EID: 20844455351     PISSN: 15250016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ymthe.2005.01.019     Document Type: Article

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