-
1
-
-
0027446925
-
2-adrenergic agonist. A review of its pharmacodynamic characteristics
-
2-adrenergic agonist. A review of its pharmacodynamic characteristics. Drugs Future 18, 49-91.
-
(1989)
Drugs Future
, vol.18
, pp. 49-91
-
-
Aantaa, R.1
Kallio, A.2
Virtanen, R.3
-
2
-
-
0020049509
-
2 adrenoreceptor mediated hyperpolarization of locus coeruleus neurons: Intracellular studies in vivo
-
2 adrenoreceptor mediated hyperpolarization of locus coeruleus neurons: intracellular studies in vivo. Science 215, 1394-1396.
-
(1982)
Science
, vol.215
, pp. 1394-1396
-
-
Aghajanian, G.1
VanderMaelen, C.2
-
3
-
-
0030063954
-
Cardiopulmonary effects of combinations of medetomidine hydrochloride and atropine sulphate in dogs
-
Alibhai H, Clarke K, Lee Y et al. (1996) Cardiopulmonary effects of combinations of medetomidine hydrochloride and atropine sulphate in dogs. Vet Rec 138, 11-13.
-
(1996)
Vet Rec
, vol.138
, pp. 11-13
-
-
Alibhai, H.1
Clarke, K.2
Lee, Y.3
-
4
-
-
0031793111
-
Comparison of three doses of dexmedetomidine with medetomidine in cats following intramuscular administration
-
Ansah O, Raekallio M, Vainio O (1998) Comparison of three doses of dexmedetomidine with medetomidine in cats following intramuscular administration. J Vet Pharmacol Ther 21, 380-387.
-
(1998)
J Vet Pharmacol Ther
, vol.21
, pp. 380-387
-
-
Ansah, O.1
Raekallio, M.2
Vainio, O.3
-
5
-
-
0034097459
-
Correlation between serum concentrations following intravenous infusion of dexmedetomidine or medetomidine in cats and their sedative and analgesic effects
-
Ansah O, Raekallio M, Vainio O (2000) Correlation between serum concentrations following intravenous infusion of dexmedetomidine or medetomidine in cats and their sedative and analgesic effects. J Vet Pharmacol Ther 23, 1-8.
-
(2000)
J Vet Pharmacol Ther
, vol.23
, pp. 1-8
-
-
Ansah, O.1
Raekallio, M.2
Vainio, O.3
-
6
-
-
0023936423
-
Lack of analgesic effect of opioids on neuropathic and idiopathic forms of pain
-
Arner S, Meyerson B (1988) Lack of analgesic effect of opioids on neuropathic and idiopathic forms of pain. Pain 33, 11-23.
-
(1988)
Pain
, vol.33
, pp. 11-23
-
-
Arner, S.1
Meyerson, B.2
-
7
-
-
0020608381
-
Effects of intracisternal and intravenous alpha-methyldopa and clonidine on haemodynamics and baroreceptor-heart rate reflex properties in conscious rabbits
-
Badoer E, Head G, Korner P (1983) Effects of intracisternal and intravenous alpha-methyldopa and clonidine on haemodynamics and baroreceptor-heart rate reflex properties in conscious rabbits. J Cardiovasc Pharmacol 5, 760-767.
-
(1983)
J Cardiovasc Pharmacol
, vol.5
, pp. 760-767
-
-
Badoer, E.1
Head, G.2
Korner, P.3
-
8
-
-
0009754840
-
Evaluation of the analgesic properties of acepromazine maleate, oxymorphone, medetomidine and a combination of acepromazine-oxymorphone
-
Barnhart M, Hubbell J, Muir W (2000) Evaluation of the analgesic properties of acepromazine maleate, oxymorphone, medetomidine and a combination of acepromazine-oxymorphone. Vet Anaesth Analg 27, 89-96.
-
(2000)
Vet Anaesth Analg
, vol.27
, pp. 89-96
-
-
Barnhart, M.1
Hubbell, J.2
Muir, W.3
-
9
-
-
84986815942
-
Use of medetomidine and butorphanol for sedation in dogs
-
Bartram D, Diamond M, Tute A et al. (1994) Use of medetomidine and butorphanol for sedation in dogs. J Small Anim Pract 35, 495-498.
-
(1994)
J Small Anim Pract
, vol.35
, pp. 495-498
-
-
Bartram, D.1
Diamond, M.2
Tute, A.3
-
10
-
-
0018143444
-
The differential effects of 5-hydroxytryptamine, noradrenaline and raphe stimulation on nociceptive and non-nociceptive dorsal horn interneurons in the cat
-
Belcher G, Ryall R, Schaffner R (1978) The differential effects of 5-hydroxytryptamine, noradrenaline and raphe stimulation on nociceptive and non-nociceptive dorsal horn interneurons in the cat. Brain Res 151, 307-321.
-
(1978)
Brain Res
, vol.151
, pp. 307-321
-
-
Belcher, G.1
Ryall, R.2
Schaffner, R.3
-
11
-
-
0026459441
-
Haemodynamic and sedative effects of dexmedetomidine in dog
-
Bloor B, Frankland M, Alper G et al. (1992) Haemodynamic and sedative effects of dexmedetomidine in dog. J Pharmacol Exp Ther 263, 690-697.
-
(1992)
J Pharmacol Exp Ther
, vol.263
, pp. 690-697
-
-
Bloor, B.1
Frankland, M.2
Alper, G.3
-
12
-
-
0037062283
-
Perioperative anaesthetic complications in cats and dogs
-
Brodbelt D, Wood J, Young L et al. (2002) Perioperative anaesthetic complications in cats and dogs. Vet Rec 150, 616.
-
(2002)
Vet Rec
, vol.150
, pp. 616
-
-
Brodbelt, D.1
Wood, J.2
Young, L.3
-
13
-
-
0021992772
-
Heterogeneity of alpha-2 adrenergic receptors
-
Bylund D (1985) Heterogeneity of alpha-2 adrenergic receptors. Pharmacol Biochem Behav 22, 835-843.
-
(1985)
Pharmacol Biochem Behav
, vol.22
, pp. 835-843
-
-
Bylund, D.1
-
14
-
-
0025967425
-
Descending adrenergic input to the primate spinal cord and its possible role in modulation of spinothalamic tract cells
-
Carlton S, Honda CN, Willcockson WS et al. (1991) Descending adrenergic input to the primate spinal cord and its possible role in modulation of spinothalamic tract cells. Brain Res 591, 77-90.
-
(1991)
Brain Res
, vol.591
, pp. 77-90
-
-
Carlton, S.1
Honda, C.N.2
Willcockson, W.S.3
-
15
-
-
0023931404
-
Transmural differences in sympathetic coronary constriction during exercise in the presence of coronary stenosis
-
Chilian W, Ackell P (1988) Transmural differences in sympathetic coronary constriction during exercise in the presence of coronary stenosis. Circ Res 62, 216-225.
-
(1988)
Circ Res
, vol.62
, pp. 216-225
-
-
Chilian, W.1
Ackell, P.2
-
16
-
-
84984053329
-
A survey of anaesthesia in small animal practice: AVA/BSAVA report
-
Clarke K, Hall L (1990) A survey of anaesthesia in small animal practice: AVA/BSAVA report. Vet Anaesth Analg 17, 4-10.
-
(1990)
Vet Anaesth Analg
, vol.17
, pp. 4-10
-
-
Clarke, K.1
Hall, L.2
-
17
-
-
0001589399
-
Mechanisms controlling cardiac autonomic function and their relation to arrhythmogenesis
-
Fozzard H, Haber E, Jennings R, Katz A, Morgan H (eds). Raven, New York
-
Corr P, Yamada K, Witkowski F (1986) Mechanisms controlling cardiac autonomic function and their relation to arrhythmogenesis. In: The Heart and Cardiovascular System. Fozzard H, Haber E, Jennings R, Katz A, Morgan H (eds). Raven, New York, pp. 1343-1403.
-
(1986)
The Heart and Cardiovascular System
, pp. 1343-1403
-
-
Corr, P.1
Yamada, K.2
Witkowski, F.3
-
18
-
-
0026440614
-
Direct coronary and cerebral vascular responses to dexmedetomidine
-
Coughlan M, Lee JG, Bosnjak ZJ et al. (1992) Direct coronary and cerebral vascular responses to dexmedetomidine. Anaesthesiology 77, 998-1006.
-
(1992)
Anaesthesiology
, vol.77
, pp. 998-1006
-
-
Coughlan, M.1
Lee, J.G.2
Bosnjak, Z.J.3
-
19
-
-
0027397075
-
2-Adrenergic receptor agonist effects on supraventricular and ventricular automaticity in dogs with complete atrioventricular block
-
2-Adrenergic receptor agonist effects on supraventricular and ventricular automaticity in dogs with complete atrioventricular block. Am J Vet Res 54, 136-141.
-
(1993)
Am J Vet Res
, vol.54
, pp. 136-141
-
-
Day, T.K.1
Muir III, W.W.2
-
20
-
-
0033860761
-
The effects of increasing plasma concentrations of dexmedetomidine in humans
-
Ebert TJ, Hall JE, Barney JA et al. (2000) The effects of increasing plasma concentrations of dexmedetomidine in humans. Anaesthesiology 93, 382-394.
-
(2000)
Anaesthesiology
, vol.93
, pp. 382-394
-
-
Ebert, T.J.1
Hall, J.E.2
Barney, J.A.3
-
21
-
-
0027461082
-
Reduction of isoflurane anaesthetic requirement by medetomidine and its restoration by atipamezole in dogs
-
Ewing KK, Mohammed HO, Scarlett J et al. (1993) Reduction of isoflurane anaesthetic requirement by medetomidine and its restoration by atipamezole in dogs. Am J Vet Res 54, 294-299.
-
(1993)
Am J Vet Res
, vol.54
, pp. 294-299
-
-
Ewing, K.K.1
Mohammed, H.O.2
Scarlett, J.3
-
23
-
-
0020676313
-
Coronary physiology
-
Feigl E (1983) Coronary physiology. Physiol Rev 63, 1-205.
-
(1983)
Physiol Rev
, vol.63
, pp. 1-205
-
-
Feigl, E.1
-
24
-
-
0026059514
-
Antinociceptive properties of intrathecal dexmedetomidine in rats
-
Fisher B, Zornow M, Yaksh H et al. (1991) Antinociceptive properties of intrathecal dexmedetomidine in rats. Eur J Pharmacol 192, 221-225.
-
(1991)
Eur J Pharmacol
, vol.192
, pp. 221-225
-
-
Fisher, B.1
Zornow, M.2
Yaksh, H.3
-
25
-
-
0026681279
-
Effect of dexmedetomidine, an alpha 2 adrenergic agonist, in the isolated heart
-
Flacke W, Flacke J, Blow K et al. (1992) Effect of dexmedetomidine, an alpha 2 adrenergic agonist, in the isolated heart. J Cardiothorac Vasc Anesth 6, 418-423.
-
(1992)
J Cardiothorac Vasc Anesth
, vol.6
, pp. 418-423
-
-
Flacke, W.1
Flacke, J.2
Blow, K.3
-
26
-
-
0027397140
-
Effects of dexmedetomidine on systemic and coronary haemodynamics in the anesthetized dog
-
Flacke W, Flacke J, Bloor B et al. (1993) Effects of dexmedetomidine on systemic and coronary haemodynamics in the anesthetized dog. J Cardiothorac Vasc Anesth 7, 41-49.
-
(1993)
J Cardiothorac Vasc Anesth
, vol.7
, pp. 41-49
-
-
Flacke, W.1
Flacke, J.2
Bloor, B.3
-
27
-
-
0021910919
-
An alpha 2 receptor mediates the selective inhibition by noradrenaline of nociceptive responses of identified dorsal horn neurones
-
Fleetwood-Walker S, Mitchell R, Hope P et al. (1985) An alpha 2 receptor mediates the selective inhibition by noradrenaline of nociceptive responses of identified dorsal horn neurones. Brain Res 334, 243-254.
-
(1985)
Brain Res
, vol.334
, pp. 243-254
-
-
Fleetwood-Walker, S.1
Mitchell, R.2
Hope, P.3
-
28
-
-
0033980903
-
Duration of nonresponse to noxious stimulation after intramuscular administration of butorphanol, medetomidine, or a butorphanol-medetomidine combination during isoflurane administration in dogs
-
Grimm K, Tranquilli W, Thurmon J et al. (2000) Duration of nonresponse to noxious stimulation after intramuscular administration of butorphanol, medetomidine, or a butorphanol-medetomidine combination during isoflurane administration in dogs. Am J Vet Res 61, 42-47.
-
(2000)
Am J Vet Res
, vol.61
, pp. 42-47
-
-
Grimm, K.1
Tranquilli, W.2
Thurmon, J.3
-
29
-
-
0029986291
-
Dexmedetomidine injection into the locus ceruleus produces antinociception
-
Guo T, Jiang J, Buttermann A et al. (1996) Dexmedetomidine injection into the locus ceruleus produces antinociception. Anesthesiology 84, 873-881.
-
(1996)
Anesthesiology
, vol.84
, pp. 873-881
-
-
Guo, T.1
Jiang, J.2
Buttermann, A.3
-
30
-
-
0028979177
-
The antinociceptive action of an alpha-2-adrenoceptor agonist in the spinal dorsal horn is due to a direct spinal action and not due to activation of descending inhibition
-
Hämäläinen M, Pertovaara A (1995) The antinociceptive action of an alpha-2-adrenoceptor agonist in the spinal dorsal horn is due to a direct spinal action and not due to activation of descending inhibition. Brain Res Bull 37, 581-587.
-
(1995)
Brain Res Bull
, vol.37
, pp. 581-587
-
-
Hämäläinen, M.1
Pertovaara, A.2
-
31
-
-
84984062747
-
The effect of medetomidine premedication upon propofol induction and infusion anaesthesia in the dog
-
Hammond RA, England GCW (1994) The effect of medetomidine premedication upon propofol induction and infusion anaesthesia in the dog. JVAA 21, 24-28.
-
(1994)
JVAA
, vol.21
, pp. 24-28
-
-
Hammond, R.A.1
England, G.C.W.2
-
32
-
-
0026037565
-
Dexmedetomidine prevents epinephrine induced arrhythmias through stimulation of central alpha-2 adrenoceptors in halothane anaesthetized dogs
-
Hayashi Y, Sumikawa K, Maze M et al. (1991) Dexmedetomidine prevents epinephrine induced arrhythmias through stimulation of central alpha-2 adrenoceptors in halothane anaesthetized dogs. Anaesthesiology 75, 113-117.
-
(1991)
Anaesthesiology
, vol.75
, pp. 113-117
-
-
Hayashi, Y.1
Sumikawa, K.2
Maze, M.3
-
33
-
-
0031007028
-
Medetomidine as a premedicant for ketamine, propofol or fentanyl anaesthesia in dogs
-
Hellebrekers L, Sap R (1997) Medetomidine as a premedicant for ketamine, propofol or fentanyl anaesthesia in dogs. Vet Rec 140, 545-548.
-
(1997)
Vet Rec
, vol.140
, pp. 545-548
-
-
Hellebrekers, L.1
Sap, R.2
-
34
-
-
0032490391
-
Clinical efficacy and safety of propofol or ketamine anaesthesia in dogs premedicated with medetomidine
-
Hellebrekers L, van Herpen H, Hird JF et al. (1998) Clinical efficacy and safety of propofol or ketamine anaesthesia in dogs premedicated with medetomidine. Vet Rec 142, 631-634.
-
(1998)
Vet Rec
, vol.142
, pp. 631-634
-
-
Hellebrekers, L.1
Van Herpen, H.2
Hird, J.F.3
-
35
-
-
0021178761
-
Alpha-1 and alpha-2 adrenoreceptor mediated vasoconstriction of large and small canine coronary arteries in vivo
-
Heusch G, Deussen A, Schipke J et al. (1984) Alpha-1 and alpha-2 adrenoreceptor mediated vasoconstriction of large and small canine coronary arteries in vivo. J Cardiovasc Pharmacol 6, 961-968.
-
(1984)
J Cardiovasc Pharmacol
, vol.6
, pp. 961-968
-
-
Heusch, G.1
Deussen, A.2
Schipke, J.3
-
36
-
-
0017399067
-
Blood flow measurements with radionuclide-labelled microspheres
-
Heymann M, Payne B, Hoffman J et al. (1977) Blood flow measurements with radionuclide-labelled microspheres. Prog Cardiovasc Dis 20, 55-79.
-
(1977)
Prog Cardiovasc Dis
, vol.20
, pp. 55-79
-
-
Heymann, M.1
Payne, B.2
Hoffman, J.3
-
37
-
-
0029113304
-
Possible structural and functional relationships between imidazoline receptors and alpha 2-adrenoreceptors
-
Hieble J, Ruffolo R (1995) Possible structural and functional relationships between imidazoline receptors and alpha 2-adrenoreceptors. Ann N Y Acad Sci 763, 8-21.
-
(1995)
Ann N Y Acad Sci
, vol.763
, pp. 8-21
-
-
Hieble, J.1
Ruffolo, R.2
-
38
-
-
0025043701
-
Effects of dexmedetomidine on contractility, relaxation and intracellular calcium transients of isolated ventricular myocardium
-
Housmans P (1990) Effects of dexmedetomidine on contractility, relaxation and intracellular calcium transients of isolated ventricular myocardium. Anaesthesiology 73, 919-922.
-
(1990)
Anaesthesiology
, vol.73
, pp. 919-922
-
-
Housmans, P.1
-
39
-
-
0028794042
-
Role of the vagus nerve in the antidysrhythmic effect of dexmedetomidine on halothane/epinephrine dysrhythmias in dogs
-
Kamibayashi T, Hayashi Y, Mammoto T et al. (1995a) Role of the vagus nerve in the antidysrhythmic effect of dexmedetomidine on halothane/epinephrine dysrhythmias in dogs. Anesthesiology 83, 992-999.
-
(1995)
Anesthesiology
, vol.83
, pp. 992-999
-
-
Kamibayashi, T.1
Hayashi, Y.2
Mammoto, T.3
-
40
-
-
0028789538
-
Further characterization of the receptor mechanism involved in the antidysrhythmic effect of dexmedetomidine on halothane/epinephrine dysrhythmias in dogs
-
Kamibayashi T, Mammoto T, Hayashi Y et al. (1995b) Further characterization of the receptor mechanism involved in the antidysrhythmic effect of dexmedetomidine on halothane/epinephrine dysrhythmias in dogs. Anesthesiology 83, 1082-1089.
-
(1995)
Anesthesiology
, vol.83
, pp. 1082-1089
-
-
Kamibayashi, T.1
Mammoto, T.2
Hayashi, Y.3
-
41
-
-
0032905215
-
Alpha-2 and imidazoline receptor agonists
-
Khan Z, Ferguson C, Jones R (1999) Alpha-2 and imidazoline receptor agonists. Anaesthesia 54, 146-165.
-
(1999)
Anaesthesia
, vol.54
, pp. 146-165
-
-
Khan, Z.1
Ferguson, C.2
Jones, R.3
-
42
-
-
0034657788
-
Sedative and cardiorespiratory effects of medetomidine, medetomidine-butorphanol, and medetomidine-ketamine in dogs
-
Ko J, Fox S, Mandsager R (2000) Sedative and cardiorespiratory effects of medetomidine, medetomidine-butorphanol, and medetomidine-ketamine in dogs. J Vet Med Assoc 216, 1578-1583.
-
(2000)
J Vet Med Assoc
, vol.216
, pp. 1578-1583
-
-
Ko, J.1
Fox, S.2
Mandsager, R.3
-
43
-
-
0012142031
-
Clinical effects and pharmacokinetics of medetomidine and its enantiomers in dogs
-
Kuusela E, Raekallio M, Antilla M et al. (2000) Clinical effects and pharmacokinetics of medetomidine and its enantiomers in dogs. J Vet Pharmacol Ther 23, 15-20.
-
(2000)
J Vet Pharmacol Ther
, vol.23
, pp. 15-20
-
-
Kuusela, E.1
Raekallio, M.2
Antilla, M.3
-
44
-
-
0034956112
-
Comparison of medetomidine and dexmedetomidine as premedicants in dogs undergoing propofol-isoflurane anaesthesia
-
Kuusela E, Raekallio M, Vainio O et al. (2001) Comparison of medetomidine and dexmedetomidine as premedicants in dogs undergoing propofol-isoflurane anaesthesia. Am J Vet Res 62, 1073-1080.
-
(2001)
Am J Vet Res
, vol.62
, pp. 1073-1080
-
-
Kuusela, E.1
Raekallio, M.2
Vainio, O.3
-
45
-
-
0038173752
-
A comparison of propofol infusion and propofol/isoflurane anaesthesia in dexmedetomidine premedicated dogs
-
Kuusela E, Vainio O, Short CE et al. (2003) A comparison of propofol infusion and propofol/isoflurane anaesthesia in dexmedetomidine premedicated dogs. J Vet Pharmacol Ther 26, 199-204.
-
(2003)
J Vet Pharmacol Ther
, vol.26
, pp. 199-204
-
-
Kuusela, E.1
Vainio, O.2
Short, C.E.3
-
46
-
-
0019116111
-
Presynaptic regulation of the release of catecholamines
-
Langer S (1981) Presynaptic regulation of the release of catecholamines. Pharmacol Rev 32, 337-362.
-
(1981)
Pharmacol Rev
, vol.32
, pp. 337-362
-
-
Langer, S.1
-
47
-
-
0030031663
-
The effect of dexmedetomidine on the balance of myocardial energy requirement and oxygen supply and demand
-
Lawrence C, Prinzen F, de Lange S (1996a) The effect of dexmedetomidine on the balance of myocardial energy requirement and oxygen supply and demand. Anesth Analg 82, 544-550.
-
(1996)
Anesth Analg
, vol.82
, pp. 544-550
-
-
Lawrence, C.1
Prinzen, F.2
De Lange, S.3
-
48
-
-
0029905855
-
The effect of dexmedetomidine on nutrient organ blood flow
-
Lawrence C, Prinzen F, de Lange S (1996b) The effect of dexmedetomidine on nutrient organ blood flow. Anesth Analg 83, 1160-1165.
-
(1996)
Anesth Analg
, vol.83
, pp. 1160-1165
-
-
Lawrence, C.1
Prinzen, F.2
De Lange, S.3
-
49
-
-
0027571817
-
Haemodynamic effects of atropine and glycopyrrolate in xylazine-isoflurane-anaesthetized dogs
-
Lemke K, Tranquilli W, Thurmon J et al. (1992) Haemodynamic effects of atropine and glycopyrrolate in xylazine-isoflurane-anaesthetized dogs. Vet Surg 22, 163-169.
-
(1992)
Vet Surg
, vol.22
, pp. 163-169
-
-
Lemke, K.1
Tranquilli, W.2
Thurmon, J.3
-
50
-
-
0029739504
-
Cardiovascular regulation in mice lacking alpha(2)-adrenergic receptor subtypes b and c
-
Link R, Desai K, Hein L et al. (1996) Cardiovascular regulation in mice lacking alpha(2)-adrenergic receptor subtypes b and c. Science 273, 803-805.
-
(1996)
Science
, vol.273
, pp. 803-805
-
-
Link, R.1
Desai, K.2
Hein, L.3
-
51
-
-
0024375987
-
Alpha adrenergic inhibition of sympathetic neurotranmsmitter release mediated by modulation of N-type calcium-channel gating
-
Lipscombe D, Kongsamt S, Tsien R (1989) Alpha adrenergic inhibition of sympathetic neurotranmsmitter release mediated by modulation of N-type calcium-channel gating. Nature 340, 639-642.
-
(1989)
Nature
, vol.340
, pp. 639-642
-
-
Lipscombe, D.1
Kongsamt, S.2
Tsien, R.3
-
52
-
-
0029086846
-
Distribution and pharmacology of alpha 2 adrenoceptors in the central nervous system
-
MacDonald E, Scheinin M (1995) Distribution and pharmacology of alpha 2 adrenoceptors in the central nervous system. J Physiol Pharmacol 46, 241-258.
-
(1995)
J Physiol Pharmacol
, vol.46
, pp. 241-258
-
-
MacDonald, E.1
Scheinin, M.2
-
53
-
-
0026319640
-
Comparison of the behavioural and neurochemical effects of the two optical enantiomers of medetomidine, a selective alpha-2-adrenoceptor agonist
-
MacDonald E, Scheinin M, Scheinin H et al. (1991) Comparison of the behavioural and neurochemical effects of the two optical enantiomers of medetomidine, a selective alpha-2-adrenoceptor agonist. J Pharmacol Exp Ther 259, 848-854.
-
(1991)
J Pharmacol Exp Ther
, vol.259
, pp. 848-854
-
-
MacDonald, E.1
Scheinin, M.2
Scheinin, H.3
-
54
-
-
0025903494
-
Alpha-2 adrenoceptor agonists: Defining the role in clinical anaesthesia
-
Maze M, Tranquilli W (1991) Alpha-2 adrenoceptor agonists: defining the role in clinical anaesthesia. Anesthesiology 74, 581-605.
-
(1991)
Anesthesiology
, vol.74
, pp. 581-605
-
-
Maze, M.1
Tranquilli, W.2
-
55
-
-
0023725934
-
Pharmacological treatment of neuralgic and neuropathic pain
-
McQuay H (1988) Pharmacological treatment of neuralgic and neuropathic pain. Cancer Surv 7, 141-159.
-
(1988)
Cancer Surv
, vol.7
, pp. 141-159
-
-
McQuay, H.1
-
56
-
-
0016552529
-
Effects of xylazine and acetylpromazine upon induced ventricular fibrillation in dogs anaesthetized with thiamylal and halothane
-
Muir W, Werner L, Hamlin R (1975) Effects of xylazine and acetylpromazine upon induced ventricular fibrillation in dogs anaesthetized with thiamylal and halothane. Am J Vet Res 36, 1299-1303.
-
(1975)
Am J Vet Res
, vol.36
, pp. 1299-1303
-
-
Muir, W.1
Werner, L.2
Hamlin, R.3
-
57
-
-
0022468125
-
Adrenergic vasoconstriction lessens transmural steal during coronary hypoperfusion
-
Nathan N, Feigl E (1986) Adrenergic vasoconstriction lessens transmural steal during coronary hypoperfusion. Am J Physiol 19, H645-H653.
-
(1986)
Am J Physiol
, vol.19
-
-
Nathan, N.1
Feigl, E.2
-
58
-
-
0025665186
-
Antinociceptive interaction between opioids and medetomidine: Systemic addivity and spinal synergy
-
Ossipov M, Harris S, LLoyd P et al. (1990) Antinociceptive interaction between opioids and medetomidine: systemic addivity and spinal synergy. Anaesthesiology 73, 1227-1235.
-
(1990)
Anaesthesiology
, vol.73
, pp. 1227-1235
-
-
Ossipov, M.1
Harris, S.2
Lloyd, P.3
-
59
-
-
0014446524
-
The inhibitory action of noradrenaline and adrenaline on acetylcholine output by guinea-pig ileum longitudinal muscle strip
-
Paton W, Vizi E (1969) The inhibitory action of noradrenaline and adrenaline on acetylcholine output by guinea-pig ileum longitudinal muscle strip. Br J Pharmacol 35, 10-28.
-
(1969)
Br J Pharmacol
, vol.35
, pp. 10-28
-
-
Paton, W.1
Vizi, E.2
-
60
-
-
0027531598
-
Antinociception induced by alpha-2-adrenoceptor agonists, with special emphasis on medetomidine studies
-
Pertovaara A (1993) Antinociception induced by alpha-2-adrenoceptor agonists, with special emphasis on medetomidine studies. Prog Neurobiol 40, 691-709.
-
(1993)
Prog Neurobiol
, vol.40
, pp. 691-709
-
-
Pertovaara, A.1
-
61
-
-
0025217307
-
The effect of medetomidine, an alpha-2-adrenoceptor agonist, in various pain tests
-
Pertovaara A, Kauppila A, Tukeva T (1990) The effect of medetomidine, an alpha-2-adrenoceptor agonist, in various pain tests. Eur J Pharmacol 179, 323-328.
-
(1990)
Eur J Pharmacol
, vol.179
, pp. 323-328
-
-
Pertovaara, A.1
Kauppila, A.2
Tukeva, T.3
-
62
-
-
0025769049
-
Involvement of supraspinal and spinal segmental alpha-2-adrenergic mechanisms in medetomidine-induced antinociception
-
Pertovaara A, Hämäläinen M, Jyvasjarvi E et al. (1991) Involvement of supraspinal and spinal segmental alpha-2-adrenergic mechanisms in medetomidine-induced antinociception. Neuroscience 44, 705-714.
-
(1991)
Neuroscience
, vol.44
, pp. 705-714
-
-
Pertovaara, A.1
Hämäläinen, M.2
Jyvasjarvi, E.3
-
63
-
-
0039538260
-
A comparison of the sedative and analgesic effects of buprenorphine in combination with acepromazine, midazolam or medetomidine in dogs
-
Pypendop B, Verstegen J (1994) A comparison of the sedative and analgesic effects of buprenorphine in combination with acepromazine, midazolam or medetomidine in dogs. Vet Anaesth Analg 21, 15-20.
-
(1994)
Vet Anaesth Analg
, vol.21
, pp. 15-20
-
-
Pypendop, B.1
Verstegen, J.2
-
64
-
-
0032199173
-
Haemodynamic effects of medetomidine in the dog: A dose titration study
-
Pypendop B, Verstegen J (1998) Haemodynamic effects of medetomidine in the dog: a dose titration study. Vet Surg 27, 612-622.
-
(1998)
Vet Surg
, vol.27
, pp. 612-622
-
-
Pypendop, B.1
Verstegen, J.2
-
65
-
-
27644496743
-
Effects of a medetomidine-midazolam-butorphanol combination on renal cortical, intestinal and muscle microvascular blood flow in isoflurane anaesthetized dogs: A laser Doppler study
-
Pypendop B, Verstegen J (2000) Effects of a medetomidine-midazolam- butorphanol combination on renal cortical, intestinal and muscle microvascular blood flow in isoflurane anaesthetized dogs: a laser Doppler study. Vet Anaesth Analg 27, 36-44.
-
(2000)
Vet Anaesth Analg
, vol.27
, pp. 36-44
-
-
Pypendop, B.1
Verstegen, J.2
-
66
-
-
0029814131
-
Coronary vascular effects of dexmedetomidine during reactive hyperemia in the anaesthetized dog
-
Roekaerts P, Prinzen F, de Lange S (1996a) Coronary vascular effects of dexmedetomidine during reactive hyperemia in the anaesthetized dog. J Cardiothorac Vasc Anesth 10, 619-626.
-
(1996)
J Cardiothorac Vasc Anesth
, vol.10
, pp. 619-626
-
-
Roekaerts, P.1
Prinzen, F.2
De Lange, S.3
-
67
-
-
0029775860
-
Beneficial effects of dexmedetomidine on ischaemic myocardium of anaesthetized dogs
-
Roekaerts P, Prinzen F, de Lange D (1996b) Beneficial effects of dexmedetomidine on ischaemic myocardium of anaesthetized dogs. Br J Anaesth 77, 427-429.
-
(1996)
Br J Anaesth
, vol.77
, pp. 427-429
-
-
Roekaerts, P.1
Prinzen, F.2
De Lange, D.3
-
68
-
-
0000815607
-
2-adrenoceptor agonist
-
Short C, Poznack AV (eds). Churchill Livingstone, New York
-
2-adrenoceptor agonist. In: Animal Pain. Short C, Poznack AV (eds). Churchill Livingstone, New York.
-
(1992)
Animal Pain
-
-
Salonen, J.1
-
69
-
-
0024352890
-
Cardiovascular actions of medetomidine and their reversal by atipamezole
-
Savola J (1989) Cardiovascular actions of medetomidine and their reversal by atipamezole. Acta Anaesthesiol Scand 85, 39-47.
-
(1989)
Acta Anaesthesiol Scand
, vol.85
, pp. 39-47
-
-
Savola, J.1
-
71
-
-
0025999215
-
2 adrenegic agonist medetomidine on systemic and coronary haemodynamics in conscious dogs
-
2 adrenegic agonist medetomidine on systemic and coronary haemodynamics in conscious dogs. Anaesthesiology 75, 499-511.
-
(1991)
Anaesthesiology
, vol.75
, pp. 499-511
-
-
Schmeling, W.1
Kampine, J.2
Roerig, D.3
-
72
-
-
27644511305
-
Effects of calcium on isolated mammalian hearts
-
Seiten E, Flacke W, Alper M (1964) Effects of calcium on isolated mammalian hearts. Am J Physiol 207, 716-720.
-
(1964)
Am J Physiol
, vol.207
, pp. 716-720
-
-
Seiten, E.1
Flacke, W.2
Alper, M.3
-
73
-
-
0026590732
-
The antinociceptive actions of dexmedetomidine on dorsal horn neuronal responses in the anaesthetized rat
-
Sullivan A, Kalso E, McQuay H et al. (1992) The antinociceptive actions of dexmedetomidine on dorsal horn neuronal responses in the anaesthetized rat. Eur J Pharmacol 215, 127-133.
-
(1992)
Eur J Pharmacol
, vol.215
, pp. 127-133
-
-
Sullivan, A.1
Kalso, E.2
McQuay, H.3
-
74
-
-
0028224258
-
Hemodynamic and analgesic effects of propofol infusion in medetomidine-premedicated dogs
-
Thurmon J, Ko J, Benson G et al. (1994) Hemodynamic and analgesic effects of propofol infusion in medetomidine-premedicated dogs. Am J Vet Res 55, 363-367.
-
(1994)
Am J Vet Res
, vol.55
, pp. 363-367
-
-
Thurmon, J.1
Ko, J.2
Benson, G.3
-
75
-
-
0026062301
-
An imidazoline specific mechanism for the hypotensive effect of clonidine. A study with yohimbine and idazoxan
-
Tibirica E, Feldman J, Mermet C et al. (1991) An imidazoline specific mechanism for the hypotensive effect of clonidine. A study with yohimbine and idazoxan. J Pharmacol Exp Ther 256, 606-613.
-
(1991)
J Pharmacol Exp Ther
, vol.256
, pp. 606-613
-
-
Tibirica, E.1
Feldman, J.2
Mermet, C.3
-
76
-
-
0023783975
-
Alterations in epinephrine-induced arrhythmogenesis after xylazine and subsequent yohombine administration in isoflurane anaesthetized dogs
-
Tranquilli W, Thurman J, Benson G (1988) Alterations in epinephrine-induced arrhythmogenesis after xylazine and subsequent yohombine administration in isoflurane anaesthetized dogs. Am J Vet Res 49, 1072-1075.
-
(1988)
Am J Vet Res
, vol.49
, pp. 1072-1075
-
-
Tranquilli, W.1
Thurman, J.2
Benson, G.3
-
77
-
-
0026001906
-
Rat spinal cord alpha-2-adrenoceptors are of the alpha-2A-subtype: Comparison with alpha-2A- and alpha-2B-adrenoceptors in rat spleen, cerebral coretx and kidney using 3H-RX821002 ligand binding
-
Uhlén S, Wikberg J (1991) Rat spinal cord alpha-2-adrenoceptors are of the alpha-2A-subtype: comparison with alpha-2A- and alpha-2B- adrenoceptors in rat spleen, cerebral coretx and kidney using 3H-RX821002 ligand binding. Pharmacol Toxicol 69, 341-350.
-
(1991)
Pharmacol Toxicol
, vol.69
, pp. 341-350
-
-
Uhlén, S.1
Wikberg, J.2
-
78
-
-
0021396341
-
Distribution of alpha-2 agonist binding sites in the rat and human central nervous system: Analysis of some functional, anatomical correlates of the pharmacological effects of clonidine and related adrenergic agents
-
Unnerstall J, Kopajtic T, Kuhar M (1984) Distribution of alpha-2 agonist binding sites in the rat and human central nervous system: analysis of some functional, anatomical correlates of the pharmacological effects of clonidine and related adrenergic agents. Brain Res Brain Res Rev 7, 69-101.
-
(1984)
Brain Res Brain Res Rev
, vol.7
, pp. 69-101
-
-
Unnerstall, J.1
Kopajtic, T.2
Kuhar, M.3
-
79
-
-
0028148281
-
2 agonist, alleviates post thoracotomy pain in dogs
-
2 agonist, alleviates post thoracotomy pain in dogs. Lab Anim 28, 369-375.
-
(1994)
Lab Anim
, vol.28
, pp. 369-375
-
-
Vainio, O.1
Ojala, M.2
-
80
-
-
0025155167
-
Comaprison of the clinical utility of medetomidine/ketamine and xylazine/ketamine combinations for ovariectomy of cats
-
Verstegen J, Fargetton X, Donnay I et al. (1990) Comaprison of the clinical utility of medetomidine/ketamine and xylazine/ketamine combinations for ovariectomy of cats. Vet Rec 127, 424-426.
-
(1990)
Vet Rec
, vol.127
, pp. 424-426
-
-
Verstegen, J.1
Fargetton, X.2
Donnay, I.3
-
81
-
-
0023803045
-
Anesthetic and haemodynamic effects of the stereoisomers of medetomidine, an alpha 2 adrenergic agonist, in halothane anesthetized dogs
-
Vickery R, Sheridan B, Segal I et al. (1988) Anesthetic and haemodynamic effects of the stereoisomers of medetomidine, an alpha 2 adrenergic agonist, in halothane anesthetized dogs. Anesth Analg 67, 611-615.
-
(1988)
Anesth Analg
, vol.67
, pp. 611-615
-
-
Vickery, R.1
Sheridan, B.2
Segal, I.3
-
82
-
-
0030611941
-
Peripherally administered alpha 2 adrenoceptor agonist in the modulation of chronic allodynia induced by spinal nerve ligation in the rat
-
Wei H, Pertovaara A (1997) Peripherally administered alpha 2 adrenoceptor agonist in the modulation of chronic allodynia induced by spinal nerve ligation in the rat. Anesth Analg 85, 1122-1127.
-
(1997)
Anesth Analg
, vol.85
, pp. 1122-1127
-
-
Wei, H.1
Pertovaara, A.2
-
83
-
-
0344518926
-
Synthesis of 3H-acetylcholine in the rabbit lacrimal gland and its release by electrical field stimulation
-
Wikberg J (1979) Synthesis of 3H-acetylcholine in the rabbit lacrimal gland and its release by electrical field stimulation. Acta Physiol Scand 468 (Suppl.), 1-89.
-
(1979)
Acta Physiol Scand
, vol.468
, Issue.SUPPL.
, pp. 1-89
-
-
Wikberg, J.1
-
84
-
-
0021923603
-
Characterization of alpha 2-adrenoreceptors which increase potassium conductance in rat locus coeruleus neurones
-
Williams JT, Henderson G, North RA (1985) Characterization of alpha 2-adrenoreceptors which increase potassium conductance in rat locus coeruleus neurones. Neuroscience 14, 95-101.
-
(1985)
Neuroscience
, vol.14
, pp. 95-101
-
-
Williams, J.T.1
Henderson, G.2
North, R.A.3
-
85
-
-
0022644386
-
Cardiovascular responses to the stimulation of alpha 1 and alpha 2 -adrenoreceptors in the conscious dog
-
Woodman O, Vatner S (1986) Cardiovascular responses to the stimulation of alpha 1 and alpha 2 -adrenoreceptors in the conscious dog. J Pharmacol Exp Ther 237, 86-91.
-
(1986)
J Pharmacol Exp Ther
, vol.237
, pp. 86-91
-
-
Woodman, O.1
Vatner, S.2
-
86
-
-
0034123877
-
The dissociation of sedative from spinal antinociceptive effects following adminsitration of a novel alpha-2-adrenoceptor agonist, MPV-2426, in the locus coeruleus in the rat
-
Xu M, Wei H, Kontinen K et al. (2000) The dissociation of sedative from spinal antinociceptive effects following adminsitration of a novel alpha-2-adrenoceptor agonist, MPV-2426, in the locus coeruleus in the rat. Acta Anaesthesiol Scand 44, 648-655.
-
(2000)
Acta Anaesthesiol Scand
, vol.44
, pp. 648-655
-
-
Xu, M.1
Wei, H.2
Kontinen, K.3
-
87
-
-
0021966740
-
Pharmacology of spinal adrenergic systems which modulate spinal nociceptive processing
-
Yaksh T (1985) Pharmacology of spinal adrenergic systems which modulate spinal nociceptive processing. Pharmacol Biochem Behav 22, 845-858.
-
(1985)
Pharmacol Biochem Behav
, vol.22
, pp. 845-858
-
-
Yaksh, T.1
-
88
-
-
0028817588
-
Reversal of nerve-ligation induced allodynia by spinal alpha 2 adrenoceptor agonists
-
Yaksh T, Pogrel J, Lee YW et al. (1995) Reversal of nerve-ligation induced allodynia by spinal alpha 2 adrenoceptor agonists. J Pharmacol Exp Ther 272, 207-214.
-
(1995)
J Pharmacol Exp Ther
, vol.272
, pp. 207-214
-
-
Yaksh, T.1
Pogrel, J.2
Lee, Y.W.3
-
89
-
-
84985383847
-
Medetomidine as a premedicant in dogs and its reversal by atipamezole
-
Young L, Brearley J, Richards D et al. (1990) Medetomidine as a premedicant in dogs and its reversal by atipamezole. J Small Anim Pract 31, 554-559.
-
(1990)
J Small Anim Pract
, vol.31
, pp. 554-559
-
-
Young, L.1
Brearley, J.2
Richards, D.3
-
90
-
-
0021354440
-
Hemodynamic profiles of methohexamine and B-HT 933 in spinalized ganglion blocked dogs
-
Zanderberg P, Timmermans P, Zwieten PV (1984) Hemodynamic profiles of methohexamine and B-HT 933 in spinalized ganglion blocked dogs. J Cardiovasc Pharmacol 6, 256-262.
-
(1984)
J Cardiovasc Pharmacol
, vol.6
, pp. 256-262
-
-
Zanderberg, P.1
Timmermans, P.2
Zwieten, P.V.3
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