Effects and possible anti-tumor immunity of electrochemotherapy with bleomycin on human colon cancer xenografts in nude mice

World Journal of Gastroenterology

Volumn 11, Issue 16, 2005, Pages 2426-2430

  Zheng, Min Hua ^a   Feng, Bo ^a   Li, Jian Wen ^a   Lu, Ai Guo ^a   Wang, Ming Liang ^a   Hu, Wei Guo ^a   Sun, Ji Yuan ^a   Hu, Yan Yan ^a   Ma, Jun Jun ^a   Yu, Bao Ming ^a  

^a SHANGHAI SECOND MEDICAL UNIVERSITY   (China)

Author keywords

Anti tumor immunity; Bleomycin; Colorectal neoplasm; Electrochemotherapy; Nude mice

Indexed keywords

BLEOMYCIN; LACTATE DEHYDROGENASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; BLOOD VESSEL INJURY; CANCER CELL CULTURE; CELL INFILTRATION; CELLULAR IMMUNITY; CHEMOSENSITIVITY; COLON CANCER; CONTROLLED STUDY; CYTOTOXICITY; DRUG EFFICACY; ELECTROCHEMOTHERAPY; ELECTROPORATION; ENZYME ASSAY; ENZYME RELEASE; EXPERIMENTAL ANIMAL; HISTOPATHOLOGY; HUMAN; HUMAN CELL; INOCULATION; LYMPHOKINE ACTIVATED KILLER CELL; MALE; MOUSE; NATURAL KILLER CELL; NONHUMAN; NUDE MOUSE; RANDOMIZATION; SPLEEN CELL; STATISTICAL SIGNIFICANCE; T LYMPHOCYTE; TUMOR NECROSIS; TUMOR VOLUME; TUMOR XENOGRAFT; WEIGHT;

EID: 20844442461     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.v11.i16.2426     Document Type: Article

References (22)

1. Jemal A, Thomas A, Murray T, Thun M. Cancer statistics, 2002. CA Cancer J Clin 2002; 52: 23-47
2. Mir LM, Orlowski S, Belehradek J Jr, Paoletti C. Electrochemotherapy potentiation of antitumour effect of bleomycin by local electric pulses. Eur J Cancer 1991; 27: 68-72
3. Gehl J, Skovsgaard T, Mir LM. Enhancement of cytotoxicity by electropermeabilization: an improved method for screening drugs. Anticancer Drugs 1998; 9: 319-325
4. Kuriyama S, Matsumoto M, Mitoro A, Tsujinoue H, Nakatani T, Fukui H, Tsujii T. Electrochemotherapy for colorectal cancer with commonly used chemotherapeutic agents in a mouse model. Dig Dis Sci 2000; 45: 1568-1577
5. Rodriguez-Cuevas S, Barroso-Bravo S, Almanza-Estrada J, Cristobal-Martinez L, Gonzalez-Rodriguez E. Electrochemotherapy in primary and metastatic skin tumors: phase II trial using intralesional bleomycin. Arch Med Res 2001; 32: 273-276
6. Chazal M, Benchimol D, Baque P, Pierrefite V, Milano G, Bourgeon A. Treatment of hepatic metastases of colorectal cancer by electrochemotherapy: an experimental study in the rat. Surgery 1998; 124: 536-540
7. Kuriyama S, Tsujinoue H, Toyokawa Y, Mitoro A, Nakatani T, Yoshiji H, Tsujimoto T, Fukui H. A potential approach for electrochemotherapy against colorectal carcinoma using a clinically available alternating current system with bipolar snare in a mouse model. Scand J Gastroenterol 2001; 36: 297-302
8. Mitsui K, Kato K, Nakamura K, Yamada Y, Honda N, Fukatsu H, Yoshikawa K. Effective treatment of bladder tumor-bearing mice by direct delivery of bleomycin using electrochemotherapy. Drug Deliv 2002; 9: 249-252
9. Kitamura A. Bleomycin-mediated electrochemotherapy in mouse NR-S1 carcinoma. Cancer Chemother Pharmacol 2003; 51: 359-362
10. Shimizu T, Nikaido T, Gomyo H, Yoshimura Y, Horiuchi A, Isobe K, Ebara S, Takaoka K. Electrochemotherapy for digital chondrosarcoma. J Orthop Sci 2003; 8: 248-251
11. Jaroszeski MJ, Dang V, Pottinger C, Hickey J, Gilbert R, Heller R. Toxicity of anticancer agents mediated by electroporation in vitro. Anticancer Drugs 2000; 11: 201-208
12. Mir LM, Tounekti O, Orlowski S. Bleomycin: revival of an old drug. Gen Pharmacol 1996; 27: 745-748
13. Sersa G, Cemazar M, Miklavcic D, Chaplin DJ. Tumor blood flow modifying effect of electrochemotherapy with bleomycin. Anticancer Res 1999; 19: 4017-4022
14. Sersa G, Krzic M, Sentjurc M, Ivanusa T, Beravs K, Kotnik V, Coer A, Swartz HM, Cemazar M. Reduced blood flow and oxygenation in SA-1 tumours after electrochemotherapy with cisplatin. Br J Cancer 2002; 87: 1047-1054
15. Mir LM, Roth C, Orlowski S, Quintin-Colonna F, Fradelizi D, Belehradek J Jr, Kourilsky P. Systemic antitumor effects of electrochemotherapy combined with histoincompatible cells secreting interleukin-2. J Immunother Emphasis Tumor Immunol 1995; 17: 30-38
16. Kuriyama S, Mitoro A, Tsujinoue H, Toyokawa Y, Nakatani T, Yoshiji H, Tsujimoto T, Okuda H, Nagao S, Fukui H. Electrochemotherapy can eradicate established colorectal carcinoma and leaves a systemic protective memory in mice. Int J Oncol 2000; 16: 979-985
17. Miyazaki S, Gunji Y, Matsubara H, Shimada H, Uesato M, Suzuki T, Kouzu T, Ochiai T. Possible involvement of antitumor immunity in the eradication of colon 26 induced by low-voltage electrochemotherapy with bleomycin. Surg Today 2003; 33: 39-44
18. Jaroszeski MJ, Coppola D, Pottinger C, Benson K, Gilbert RA, Heller R. Treatment of hepatocellular carcinoma in a rat model using electrochemotherapy. Eur J Cancer 2001; 37: 422-430
19. Smyth MJ, Hayakawa Y, Takeda K, Yagita H. New aspects of natural-killer-cell surveillance and therapy of cancer. Nat Rev Cancer 2002; 2: 850-861
20. Colucci F, Caligiuri MA, Di Santo JP. What does it take to make a natural killer? Nat Rev Immunol 2003; 3: 413-425
21. Sacchi M, Vitolo D, Sedlmayr P, Rabinowich H, Johnson JT, Herberman RB, Whiteside TL. Induction of tumor regression in experimental model of human head and neck cancer by human A-LAK cells and IL-2. Int J Cancer 1991; 47: 784-791
22. Ueda Y, Yamagishi H, Tanioka Y, Fujiwara H, Fuji N, Itoh T, Fujiki H, Yoshimura T, Oka T. Clinical application of adoptive immunotherapy and IL-2 for the treatment of advanced digestive tract cancer. Hepatogastroenterology 1999; 46: 1274-1279