2-Furoyl-LIGRL-NH 2, a potent agonist for proteinase-activated receptor-2, as a gastric mucosal cytoprotective agent in mice

British Journal of Pharmacology

Volumn 144, Issue 2, 2005, Pages 212-219

  Kawabata, Atsufumi ^a   Oono, Yuko ^a   Yonezawa, Daiki ^a   Hiramatsu, Kaori ^a   Inoi, Naoki ^a   Sekiguchi, Fumiko ^a   Honjo, Masami ^a   Hirofuchi, Michiko ^a   Kanke, Toru ^b   Ishiwata, Hiroyuki ^b  

^a KINKI UNIVERSITY   (Japan)

^b Kowa Company Limited   (Japan)

Author keywords

A potent PAR 2 agonist; Gastric mucosal protection; PAR 2 knockout mouse; Proteinase activated receptor (PAR); Salivation

Indexed keywords

2 FUROYLLEUCYLISOLEUCYLGLYCYLARGINYLLEUCINAMIDE; ALCOHOL; AMASTATIN; AMINOPEPTIDASE; CAPSAICIN; ENDOTHELIUM DERIVED HYPERPOLARIZING FACTOR; GASTROINTESTINAL AGENT; HYDROCHLORIC ACID; MESSENGER RNA; PROTEINASE ACTIVATED RECEPTOR 2; PROTEINASE ACTIVATED RECEPTOR STIMULATING AGENT; SERYLLEUCYLISOLEUCYLGLYCYLARGINYLLEUCINAMIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOASSAY; CELL PROTECTION; CONTROLLED STUDY; DRUG POTENCY; DRUG SYNTHESIS; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; KNOCKOUT MOUSE; MALE; MASS SPECTROMETRY; MOUSE; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SALIVATION; SENSORY NERVE CELL; STOMACH MUCOSA INJURY; STOMACH PROTECTION;

ANIMALS; CYTOPROTECTION; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GASTRIC MUCOSA; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; OLIGOPEPTIDES; RECEPTOR, PAR-2;

EID: 20844435292     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0706059     Document Type: Article

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