A role for the protease-sensitive loop region of Shiga-like toxin 1 in the retrotranslocation of its A1 domain from the endoplasmic reticulum lumen

Journal of Biological Chemistry

Volumn 280, Issue 24, 2005, Pages 23310-23318

  Lapointe, Paul ^a   Wei, Xin ^a   Garieṕy, Jean ^a,b  

^a UNIVERSITY OF TORONTO   (Canada)

^b PRINCESS MARGARET HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; CELLS; MOLECULAR BIOLOGY; POLYPEPTIDES; YEAST;

CYTOTOXIC EFFECT; ENDOPLASMIC RETICULUM (ER); ENZYMATIC ACTIVITY; EUKARYOTIC CELLS; RIBOSOME-INACTIVATING PROTEIN;

PROTEINS;

MUTANT PROTEIN; PROTEINASE; VEROTOXIN 1;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; CYTOPLASM; CYTOSOL; CYTOTOXICITY; ENDOPLASMIC RETICULUM; LETHALITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN MOTIF; PROTEIN TRANSPORT; SACCHAROMYCES CEREVISIAE; YEAST;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; BIOCHEMISTRY; CATALYTIC DOMAIN; CERCOPITHECUS AETHIOPS; CIRCULAR DICHROISM; CYTOPLASM; CYTOSOL; DNA PRIMERS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOPLASMIC RETICULUM; ESCHERICHIA COLI; GENE DELETION; GENETIC VECTORS; MODELS, GENETIC; MOLECULAR SEQUENCE DATA; MUTATION; PEPTIDES; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SACCHAROMYCES CEREVISIAE; SEQUENCE HOMOLOGY, AMINO ACID; SHIGA-LIKE TOXIN I; VERO CELLS;

EUKARYOTA; SACCHAROMYCES CEREVISIAE;

EID: 20744449290     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M414193200     Document Type: Article

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