Syntheses of NAMDA derivatives inhibiting NO production in BV-2 cells stimulated with lipopolysaccharide

Bioorganic and Medicinal Chemistry Letters

Volumn 15, Issue 14, 2005, Pages 3369-3373

  Jai, Woong Seo ^a   Srisook, Ekaruth ^a   Hyo, Jin Son ^b   Hwang, Onyou ^b   Cha, Young Nam ^c   Dae, Yoon Chi ^a  

^a Inha University   (South Korea)

^b University of Ulsan College of Medicine   (South Korea)

^c Inha University School of Medicine   (South Korea)

Author keywords

Inhibition of NO; Inhibition of tetrahydrobiopterin; NAMDA; Nitric oxide; Nitric oxide synthase

Indexed keywords

ALPHA METHYLDOPAMINE; CATECHOLAMINE; CATECHOLAMINE DERIVATIVE; DOPAMINE DERIVATIVE; LIPOPOLYSACCHARIDE; N ACETYL 3 O METHYLDOPAMINE; N ACETYLTETRAHYDROISOQUINOLINE; NITRIC OXIDE; TETRAHYDROBIOPTERIN; TETRAHYDROISOQUINOLINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL METABOLISM; CELL STIMULATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DRUG ACTIVITY; DRUG DESIGN; DRUG MECHANISM; DRUG SYNTHESIS; MICROGLIA; MOUSE; NONHUMAN; PHARMACOLOGICAL BLOCKING; STRUCTURE ACTIVITY RELATION;

ANIMALS; BIOPTERIN; CELL LINE; CELL SURVIVAL; DOPAMINE; DRUG DESIGN; L-LACTATE DEHYDROGENASE; LIPOPOLYSACCHARIDES; MICROGLIA; MOLECULAR STRUCTURE; NITRIC OXIDE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 20644437763     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2005.05.033     Document Type: Article

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