Isatin, an endogenous monoamine oxidase inhibitor, triggers a dose- and time-dependent switch from apoptosis to necrosis in human neuroblastoma cells

Neurochemistry International

Volumn 47, Issue 3, 2005, Pages 216-224

  Igosheva, N ^a,b   Lorz, C ^a   O'Conner, E ^c   Glover, V ^a   Mehmet, H ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b SARATOV STATE UNIVERSITY   (Russian Federation)

^c HAMMERSMITH HOSPITAL   (United Kingdom)

Author keywords

Apoptosis; Isatin; Parkinson's disease; SH SY5Y cell

Indexed keywords

ISATIN; LIPOCORTIN 5; MONOAMINE OXIDASE INHIBITOR; PROPIDIUM IODIDE;

APOPTOSIS; ARTICLE; CELL CULTURE; CELL CYCLE; CELL DEATH; CELL DIVISION; CELL LABELING; CELL LINE; CELL SURVIVAL; CELLULAR DISTRIBUTION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DOPAMINERGIC SYSTEM; DOSE RESPONSE; FLOW CYTOMETRY; FLUORESCENCE ACTIVATED CELL SORTING; HUMAN; HUMAN CELL; HYPERMETABOLISM; NECROSIS; NEUROBLASTOMA CELL; PERMEABILITY; PRIORITY JOURNAL; PROTEIN BINDING;

ANNEXIN A5; ANTIPARKINSON AGENTS; APOPTOSIS; CELL CYCLE; CELL LINE, TUMOR; CELL MEMBRANE PERMEABILITY; CELL PROLIFERATION; CELL SURVIVAL; DOPAMINE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENERGY METABOLISM; HUMANS; ISATIN; MONOAMINE OXIDASE INHIBITORS; NECROSIS; NEUROBLASTOMA; NEURONS; NEUROTOXINS; PARKINSON DISEASE; PROPIDIUM; TETRAZOLIUM SALTS; THIAZOLES; TIME FACTORS;

EID: 20544455252     PISSN: 01970186     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuint.2005.02.011     Document Type: Article

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