Comparative Study of the Effects of Isatin, an Endogenous MAO-Inhibitor, and Selegiline on Bradykinesia and Dopamine Levels in a Rat Model of Parkinson's Disease Induced by the Japanese Encephalitis Virus

NeuroToxicology

Volumn 25, Issue 1-2, 2004, Pages 205-213

  Hamaue, N ^a   Minami, M ^a   Terado, M ^a   Hirafuji, M ^a   Endo, T ^a   Machida, M ^a   Hiroshige, T ^a   Ogata, A ^b   Tashiro, K ^b   Saito, H ^c   Parvez, S H ^d  

^a HEALTH SCIENCES UNIVERSITY OF HOKKAIDO   (Japan)

^b HOKKAIDO UNIVERSITY   (Japan)

^c Department of Health Sciences   (Japan)

^d CNRS   (France)

Author keywords

Dopamine; Isatin; Japanese encephalitis virus; Monoamine oxidase inhibitor; Parkinson's disease; Selegiline

Indexed keywords

3,4 DIHYDROXYPHENYLACETIC ACID; ANTIPARKINSON AGENT; BRAIN AMINE; DOPAMINE; ISATIN; MONOAMINE OXIDASE B INHIBITOR; MONOAMINE OXIDASE INHIBITOR; NORADRENALIN; SELEGILINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRADYKINESIA; CONTROLLED STUDY; DOPAMINE BRAIN LEVEL; DRUG EFFECT; DRUG INHIBITION; ENZYME INHIBITION; JAPANESE ENCEPHALITIS VIRUS; MOTOR ACTIVITY; NONHUMAN; NORADRENALIN BRAIN LEVEL; PARKINSON DISEASE; PRIORITY JOURNAL; RAT; TASK PERFORMANCE; TREATMENT OUTCOME;

GYMNOMYZA SAMOENSIS; JAPANESE ENCEPHALITIS VIRUS;

EID: 9144230064     PISSN: 0161813X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0161-813X(03)00100-1     Document Type: Article

References (35)

1. Berry MD, Juorio AV, Paterson IA. Possible mechanisms of action of (-)deprenyl and other MAO-B inhibitors in some neurologic and psychiatric disorders. Prog Neurobiol 1994;44:141-61.
2. Bursey M, Eichenbaum H. Conservation of hippocampal memory function in rats and humans. Nature 1996;379:255-7.
3. Calne DB, Langston JW. Aetiology of Parkinson's disease. Lancet 1983;1457-9.
4. Dickerson RB, Newton JR, Hansen JE. Diagnosis and immediate prognosis of Japanese B encephalitis. Am J Med 1952;12:277-88.
5. Dluzen DE. Effects of testosterone upon MPTP-induced neurotoxicity of the nigrostriatal dopaminergic system of C57/B1 mice. Brain Res 1996;715:113-8.
6. Duvoisin RC, Yahr MD. Encephalitis and parkinsonism. Arch Neurol 1965;12:227-39.
7. Fishman PS, Gass JS, Swoveland PT, Lavi E, Highkin MK, Weiss SR. Infection of the basal ganglia by a murine coronavirus. Science 1985;229:877-9.
8. Gerlach M, Youdim MB, Riederer P. Pharmacology of selegiline. Neurology 1996;47(Suppl 3):S137-45.
9. Glover V, Reveley MA, Sandler M. A monoamine oxidase inhibitor in human urine. Biochem Pharmacol 1980;29:467-70.
10. Glover V, Halket JM, Watkins PJ, Clow A, Goodwin BL, Sandler M. Isatin: identity with the purified endogenous monoamine oxidase inhibitor tribulin. J Neurochem 1988;51:656-9.
11. Glover V, Bhattacharya SK, Sandler M. Isatin - a new biological factor. Ind J Exp Biol 1991;29:1-5.
12. 3H]dopa in various regions of the brain. J Neurochem 1966;13:655-69.
13. Hamaue N, Minami M, Kanamaru Y, Togashi M, Monma Y, Ishikura M, Mahara R, Yamazaki N, Togashi H, Saito H, Parvez SH. Endogenous monoamine oxidase (MAO) inhibitor (tribulin-like activity) in the brain and urine of stroke-prone SHR. Biog Amines 1992;8:401-12.
14. Hamaue N, Minami M, Kanamaru Y, Ishikura M, Yamazaki N, Saito H, Parvez SH. Identification of isatin, an endogenous MAO inhibitor, in the brain of stroke-prone SHR. Biog Amines 1994;10:99-110.
15. Hamaue N, Yamazaki N, Minami M, Endo T, Hirafuji M, Monma Y, Togashi H, Saito H, Parvez SH. Effects of isatin, an endogenous MAO inhibitor, on acetylcholine and dopamine levels in the rat striatum. Biog Amines 1999;15:367-77.
16. Hamaue N, Yamazaki N, Terado M, Minami M, Ohno K, Ide H, Ogata A, Honma S, Tashiro K. Urinary isatin concentrations in patients with Parkinson's disease determined by a newly developed HPLC-UV method. Res Commun Mol Pathol Pharmacol 2000;108:63-73.
17. Johnson RT, Burke DS, Elwell M, Leake CJ, Nisalak A, Hoke CH, Lorsomrudee W. Japanese encephalitis: immunocytochemical studies of viral antigen and inflammatory cells in fatal cases. Ann Neurol 1985;18:567-73.
18. Knoll J. The possible mechanisms of action of (-)deprenyl in Parkinson's disease. J Neural Transm 1978;43:177-98.
19. Kumar R, Bansal RC, Mahmood A. Isatin, an inhibitor of acetylcholinesterase activity in rat brain. Biog Amines 1993;9:281-9.
20. Kupsch A, Sautter J, Gotz ME, Breithaupt W, Schwarz J, Youdim MB, Riederer P, Gerlach M, Oertel WH. Monoamine oxidase-inhibition and MPTP-induced neurotoxicity in the non-human primate: comparison of rasagiline (TVP 1012) with selegiline. J Neural Transm 2001;108:985-1009.
21. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. Measurement with the folin phenol reagent. J Biol Chem 1951;193:265-75.
22. McIntyre IM, Norman TR. Serotonergic effects of isatin: an endogenous MAO inhibitor related to tribulin. J Neural Transm 1990;79:35-40.
23. Ogata A, Nagashima K, Hall WW, Ichikawa M, Kimura-Kuroda J, Yasui K. Japanese encephalitis virus neurotropism is dependent on the degree of neuronal maturity. J Virol 1991;65:880-6.
24. Ogata A, Tashiro K, Nukuzuma S, Nagashima K, Hall WW. A rat model of Parkinson's disease induced by Japanese encephalitis virus. J Neurovirol 1997;3:141-7.
25. Ogata A, Nagashima K, Yasui K, Matsuura T, Tashiro K. Sustained release dosage of thyrotropin-releasing hormone improves experimental Japanese encephalitis virus-induced parkinsonism in rats. J Neurol Sci 1998;159:135-9.
26. Ogata A, Hamaue N, Terado M, Minami M, Nagashima K, Tashiro K. Isatin, an endogenous MAO inhibitor, improves bradykinesia and dopamine levels in a rat model of Parkinson's disease induced by Japanese encephalitis virus. J. Neurol. Sci. 2003;206:79-83.
27. Ogawa N, Hirose Y, Ohara S, Ono T, Watanabe Y. A simple quantitative bradykinesia test in MPTP-treated mice. Res Commun Chem Pathol Pharmacol 1985;50:435-41.
28. Pracelhan S, Pandey N, Shashank S, Gupta RK, Mathur A. Parkinsonism due to predominant involvement of striantia nigra in Japanese encephlitis. Neurology 1999;53:1781-6.
29. Sandler M. The emergence of tribulin. Trends Pharmacol Sci 1982;3:471-2.
30. Shintani F, Kanba S, Nakaki T, Nibuya M, Kinoshita N, Suzuki E, Yagi G, Kato R, Asai M. Interleukin-1 beta augments release of norepinephrine, dopamine, and serotonin in the rat anterior hypothalamus. J Neurosci 1993;13:3574-81.
31. Takahashi M, Yamada T, Nakajima S, Nakajima K, Yamamoto T, Okada H. The substantia nigra is a major target for neurovirulent influenza A virus. J Exp Med 1995;181:2161-9.
32. Tipton KF, Housy MD, Mantle TJ. The nature and locations of the multiple forms of monoamine oxidase. In: Mary LC, editor. Monoamine oxidase its inhibition. New York: Elsevier; 1976. p. 5-31.
33. Tozawa Y, Ueki A, Manabe S, Matsushima K. Stress-induced increase in urinary isatin excretion in rats: reversal by both dexamethasone and α-methyl-p-tyrosine. Biochem Pharmacol 1998;56:1041-6.
34. Wallenstein S, Zucker CL, Fleiss JL. Some statistical methods useful in circulation research. Circ Res 1980;47:1-9.
35. Walters JH. Parkinson syndrome after meningoencephalitis due to coxsackie virus group, type 2. New Eng J Med 1960;263:744-7.