Inhibition of T cell MAPKs (Erk 1/2, p38) with thermal injury is related to down-regulation of Ca2+ signaling

Biochimica et Biophysica Acta - Molecular Basis of Disease

Volumn 1741, Issue 1-2, 2005, Pages 113-119

  Fazal, Nadeem ^a   Choudhry, Mashkoor A ^b   Sayeed, Mohammed M ^a  

^a LOYOLA UNIVERSITY CHICAGO   (United States)

^b UNIVERSITY OF ALABAMA SCHOOL OF MEDICINE   (United States)

Author keywords

Burn; Calcium; Cell signaling; Erk 1 2; Immune response; MAPK; p38; Rat; T cell

Indexed keywords

CALCIUM ION; IONOMYCIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; CALCIUM SIGNALING; CELLULAR IMMUNITY; CONFOCAL MICROSCOPY; CROSS LINKING; DOWN REGULATION; ENZYME INHIBITION; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; T LYMPHOCYTE; THERMAL INJURY;

ANIMALS; BURNS; CALCIUM; CALCIUM SIGNALING; DOWN-REGULATION; ENZYME ACTIVATION; IONOMYCIN; LYMPH NODES; LYMPHOCYTE ACTIVATION; MALE; MESENTERY; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PEYER'S PATCHES; PHOSPHORYLATION; RATS; RATS, SPRAGUE-DAWLEY; T-LYMPHOCYTES;

ANIMALIA;

EID: 20444481759     PISSN: 09254439     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbadis.2004.10.006     Document Type: Article

References (34)

1. M.L. Rodrick, J.J. Wood, J.T. Grbic, J.B. O'Mahony, C.F. Davis, N.M. Moss, B.A. Blazar, R.H. Demling, and J.A. Mannick Defective IL-2 production in patients with severe burns and sepsis Lymphokine Res. 5 Suppl. 1 1986 S75 S80
2. M.A. Choudhry, O. Sir, and M.M. Sayeed TGFβ abrogates TCR-mediated signaling by upregulating tyrosine phosphates in T cells Shock 15 3 2001 193 199
3. T. Ravindranath, W. Al-Ghoul, S. Namak, N. Fazal, R. Durazo-Arvizu, M. Choudhry, and M.M. Sayeed Effects of burn with and without Escherichia coli infection in rats on intestinal vs. splenic T-cell responses Crit. Care Med. 29 12 2001 (Dec.) 2245 2250
4. 59fyn tyrosine kinase in T lymphocytes during sepsis J. Immunol. 160 1 1998 929 935
5. 2 suppresses intestinal T cell function in thermal injury: a cause for enhanced bacterial translocation Shock 16 3 2001 183 188
6. 2+ mobilization in T cells Am. J. Physiol. 277 6 Pt. 2 1999 (Dec.) R1741 R1748
7. N. Isakov, and A. Altman Protein kinase C (theta) in T cell activation Annu. Rev. Immunol. 20 2002 761 794
8. G. Baier The PKC gene module: molecular biosystematics to resolve its T cell functions Immunol. Rev. 192 2003 (Apr.) 64 79
9. A. Manninen, G.H. Renkema, and K. Saksela Synergistic activation of NFAT by HIV-1 nef and the Ras/MAPK pathway J. Biol. Chem. 275 22 2000 (Jun. 2) 16513 16517
10. J.J. Yu, C.S. Tripp, and J.H. Russell Regulation and phenotype of an innate Th1 cell: role of cytokines and the p38 kinase pathway J. Immunol. 171 11 2003 (Dec. 1) 6112 6118
11. C. Dong, R.J. Davis, and R.A. Flavell MAP kinases in the immune response Annu. Rev. Immunol. 20 2002 55 72
12. R.S. Lewis Calcium oscillations in T-cells: mechanisms and consequences for gene expression Biochem. Soc. Trans. 31 Pt. 5 2003 (Oct.) 925 929
13. R.H. Schwartz T cell anergy Annu. Rev. Immunol. 21 2003 305 334
14. J. Alberola-Ila, and G. Hernandez-Hoyos The Ras/MAPK cascade and the control of positive selection Immunol. Rev. 191 2003 (Feb.) 79 96
15. J.O. Ebinu, S.L. Stang, C. Teixeira, D.A. Bottorff, J. Hooton, P.M. Blumberg, M. Barry, R.C. Bleakley, H.L. Ostergaard, and J.C. Stone RasGRP links T-cell receptor signaling to Ras Blood 95 2000 3199 3203
16. H. Kawasaki, G.M. Springett, T. Shinichiro, J.J. Canales, P. Harlan, J.P. Blumenstiel, E.J. Chen, A. Bany, N. Mochizuki, and A. Ashbacher A Rap guanine nucleotide exchange factor enriched highly in the basal ganglia Proc. Natl. Acad. Sci. U. S. A. 95 1998 13278 13283
17. C.E. Tognon, H.E. Kirk, L.A. Passmore, I.P. Whitehead, C.J. Der, and R.J. Kay Regulation of RasGRP via a phorbol ester-responsive C1 domain Mol. Cell. Biol. 18 1998 6995 7008
18. T. Yamaguchi, D.P. Wallace, B.S. Magenheimer, S.J. Hempson, J.J. Grantham, and J.P. Calvet Calcium restriction allows cAMP activation of the B-Raf/ERK pathway, switching cells to a cAMP-dependent growth-stimulated phenotype J. Biol. Chem. 279 39 2004 40419 40430
19. H. Enslen, H. Tokumitsu, P.J. Stork, R.J. Davis, and T.R. Soderling Regulation of mitogen-activated protein kinases by a caclium/calmodulin- dependent protein kinase cascade Proc. Natl. Acad. Sci. U. S. A. 93 1996 10803 10808
20. E. Aquilla, A. Whelchel, H.J. Knot, M. Nelson, and J. Posada Activation of multiple mitogen-activated protein kinase signal transduction pathways by the endothelin B receptor requires the cytoplasmic tail J. Biol. Chem. 271 1996 31572 31579
21. R.A. Franklin, P.A. Atherfold, and J.A. McCubrey Calcium-induced ERK activation in human T lymphocytes occurs via p56(Lck) and CaM-kinase Mol. Immunol. 37 11 2000 (Aug.) 675 683
22. P.A. Atherfold, M.S. Norris, P.J. Robinson, E.W. Gelfand, and R.A. Franklin Calcium-induced ERK activation in human T lymphocytes Mol. Immunol. 36 8 1999 (Jun.) 543 549
23. 2 mediated cell suppression in burn injury Shock 18 3 2002 212 216
24. 2 suppresses intestinal T cell function in thermal injury: a cause for enhanced bacterial translocation Shock 16 3 2001 183 188
25. M. Rincon MAP-kinase signaling pathways in T cells Curr. Opin. Immunol. 13 3 2001 (Jun.) 339 345
26. M.A. Choudhry, F. Haque, M. Khan, N. Fazal, W. Al-Ghoul, T. Ravindranath, R.L. Gamelli, and M.M. Sayeed Enteral nutritional supplementation prevents mesenteric lymph node T-cell suppression in burn injury Crit. Care Med. 31 6 2003 (Jun.) 1764 1770
27. 2+ Arch. Surg. 135 12 2000 (Dec.) 1432 1442
28. N. Venkatesh, Y. Feng, B. DeDecker, P. Yacono, D. Golan, T. Mitchison, and F. McKeon Chemical genetics to identify NFAT inhibitors: potential of targeting calcium mobilization in immunosuppression Proc. Natl. Acad. Sci. U. S. A. 101 24 2004 (Jun. 15) 8969 8974
29. M. Humar, N. Andriopoulos, S.E. Pischke, T. Loop, R. Schmidt, A. Hoetzel, M. Roesslein, H.L. Pahl, K.K. Geiger, and B.H. Pannen Inhibition of AP-1 by barbiturates is mediated by differential effects on MAP-kinases and the small G proteins Ras and Rac-1 J. Pharmacol. Exp. Ther. 2004 (Jul. 19)
30. D. Klingenberg, D. Gunduz, F. Hartel, K. Bindewald, M. Schafer, H.M. Piper, and T. Noll MEK/MAPK as a signaling element in ATP control of endothelial myosin light chain Am. J. Physiol., Cell Physiol. 286 4 2004 (Apr.) C807 C812
31. Q. Yu, C. Kovacs, F.Y. Yue, and M.A. Ostrowski The role of the p38 mitogen-activated protein kinase, extracellular signal-regulated kinase, and phosphoinositide-3-OH kinase signal transduction pathways in CD40 ligand-induced dendritic cell activation and expansion of virus-specific CD8+ T cell memory responses J. Immunol. 172 10 2004 (May 15) 6047 6056
32. C.R. Weston, D.G. Lambright, and R.J. Davis Signal transduction. MAP kinase signaling specificity Science 296 5577 2002 (Jun. 28) 2345 2347
33. M. Rincon, R.A. Flavell, and R.J. Davis Signal transduction by MAP kinases in T lymphocytes Oncogene 20 19 2001 (Apr. 30) 2490 2497
34. L. Chang, and M. Karin Mammalian MAP kinase signalling cascades Nature 410 6824 2001 (Mar. 1) 37 40