PGE2 suppresses mitogen-induced Ca2+ mobilization in T cells

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 277, Issue 6 46-6, 1999, Pages

  Choudhry, Mashkoor A ^a   Hockberger, Philip E ^b   Sayeed, Mohammed M ^a  

^a LOYOLA UNIVERSITY MEDICAL CENTER   (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

Author keywords

Adenosine 3,5 cyclic monophosphate; Calcium ion signaling; Concanavalin A; Intracellular calcium ion release; Prostaglandin E2; T lymphocytes

Indexed keywords

CALCIUM; CONCANAVALIN A; MITOGENIC AGENT; PROSTAGLANDIN E2; EGTAZIC ACID;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM MOBILIZATION; CALCIUM SIGNALING; CALCIUM TRANSPORT; CELL PROLIFERATION; CELL STIMULATION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; T LYMPHOCYTE; ANIMAL; CELL CULTURE; CELL MEMBRANE; DRUG EFFECT; IMMUNOLOGY; KINETICS; LYMPHOCYTE ACTIVATION; METABOLISM; PHYSIOLOGY; SPLEEN; SPRAGUE DAWLEY RAT;

ANIMALS; CALCIUM; CELL MEMBRANE; CELLS, CULTURED; CONCANAVALIN A; DINOPROSTONE; EGTAZIC ACID; KINETICS; LYMPHOCYTE ACTIVATION; MALE; RATS; RATS, SPRAGUE-DAWLEY; SPLEEN; T-LYMPHOCYTES;

EID: 0033252515     PISSN: 03636119     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpregu.1999.277.6.r1741     Document Type: Article

References (38)

1. Altman, A., T. Mustelin, and K. M. Goggeshall. T lymphocyte activation: a biological model of signal transduction. Crit. Rev. Immunol. 10: 347-391, 1990.
2. Berridge, M. J. Lymphocyte activation in health and disease. Crit. Rev. Immunol. 17: 155-178, 1997.
3. Bismuth, G., I. Theodorou, H. Gouy, S. Le Gouvello, A. Bernard, and P. Debre. Cylic AMP-mediated alteration of CD2 activation process in human T lymphocytes. Preferential inhibition of the phosphoinositide cycle-related transduction pathway. Eur. J. Immunol. 18: 1351-1357, 1988.
4. Cardenas, M E., and J. Heitman. Role of calcium in T-lymphocyte activation. In: Advances in Second Messenger and Phosphoprotein Research: Calcium Regulation of Cellular Function, edited by A. R. Means. New York: Raven, 1995, vol. 30, p. 281-298.
5. 2+ entry pathways in the plasma membrane. J. Cell. Biochem. 58: 344-359, 1995.
6. Chen, D., and E. V. Rothenberg. Interleukin 2 transcription factors as molecular targets of cAMP inhibition: delayed inhibition kinetics and combinatorial transcription roles. J. Exp. Med. 179: 931-942, 1994.
7. 2 effect on T-lymphocyte activation. J. Clin. Invest. 80: 333-340, 1987.
8. 2-induced T-lymphocyte proliferative suppression in sepsis. Infect. Immun. 63: 3101-3105, 1995.
9. 2+ signalling and proliferative responses during sepsis. Shock 1: 466-471, 1994.
10. 2. Shock 6: 101-105, 1996.
11. fyn tyrosine kinase in T lymphocytes during sepsis. J. Immunol. 160: 929-935, 1998.
12. Clapham, D. E. Calcium signaling. Cell 80: 259-268, 1995.
13. 2+]; oscillations in T lymphocytes. J. Gen. Physiol. 103: 365-388, 1994.
14. Donnadieu, E., G. Bismuth, and A. Trautmann. Calcium fluxes in T lymphocytes. J. Biol. Chem. 267: 25864-25872, 1992.
15. 2+ release in permeabilized human lymphocytes. FEBS Lett. 222: 349-352, 1987.
16. Faist, E., C. Schinkel, S. Zimmer, J. P. Kremer, G. H. Von Donnersmarck, and F. W. Schildberg. Inadequate interleukin-2 synthesis and interleukin-2 messenger expression following thermal and mechanical trauma in humans is caused by defective transmembrane signalling. J. Trauma 34: 846-854, 1993.
17. 2+ endoplasmic reticulum-ATPase inhibitor thapsigargin. J. Immunol. 147: 757-766, 1991.
18. Grbic, J. T., J. A. Mannick, D. B. Gough, and M. L. Rodrick. The role of prostaglandin E2 in immune suppression following injury. Ann. Surg. 214: 253-263, 1991.
19. Hoyt, D. B., W. G. Jugner, W. H. Loomis, and F. C. Liu. Effects of trauma on immune cell functions: impairment of intracellular calcium signaling. Shock 2: 23-28, 1994.
20. Hess, S. D., M. Oortgiesen, M., and M. D. Cahalan. Calcium oscillations in human T and natural killer cells depend upon membrane potential and calcium influx. J. Immunol. 150: 2620-2633, 1993.
21. 2+ mobilization. Biochem. J. 247: 695-700, 1987.
22. Lerner, A., B. Jacobson, and R. A. Miller. Cyclic AMP concentrations modulate both calcium flux and hydrolysis of phosphatidylinositol phosphates in mouse T lymphocytes. J. Immunol. 140: 936-940, 1988.
23. Lingk, D. S., M. A. Chan, and E. W. Gelfand. Increased cyclic adenosine monophosphate levels block progression but not initia-tion of human T cell proliferation. J. Immunol. 145: 449-455, 1990.
24. 2. J. Immunol. 145: 2616-2625, 1990.
25. 2+ imaging in single living cells: theoretical and practical issues. Cell Calcium 11: 157-179, 1990.
26. Munoz, E., A. M. Zubiaga, M. Merrow, N. P. Sautter, and B. T. Huber. Cholera toxin discriminates between T helper 1 and 2 cells in T cell receptor-mediated activation: role of cAMP in T cell proliferation. J. Exp. Med. 172: 95-103, 1990.
27. Neher, E. The influence of intracellular calcium concentration on degranulation of dialysed mast cells from rat peritoneum. J. Physiol. (Lond.) 395: 193-214, 1988.
28. Paliogianni, F., R. L. Kincaid, and D. T. Boumpas. Prostaglandin E2 and other cyclic AMP elevating agents inhibit interleukin 2 gene transcription by counteracting calcineurin-dependent pathway. J. Exp. Med. 178: 1813-1817, 1993.
29. Parekh, A. B., and R. Penner. Store depletion and calcium influx. Physiol. Rev. 77: 901-930, 1997.
30. 2+-ATPaSe inhibitors. J. Immunol. 152: 5226-5240, 1994.
31. Putney, Jr., J. W. Capacitative calcium entry revisited. Cell Calcium 11: 611-624, 1990.
32. Putney, Jr., J. W., and G. St. J. Bird. The signal for capacitative calcium entry. Cell 75: 199-201, 1993.
33. Sayeed, M. M. Alterations in cell signaling and related effector functions in T lymphocytes in burn/trauma/septic injuries. Shock 5: 157-166, 1996.
34. 2 differentially modulates cytokine secretion profiles of human T helper lymphocytes. J. Immunol. 150: 5321-5329, 1996.
35. Theze, J, P. M. Alzari, and J. Bertoglio. Interleukin 2 and its receptors: recent advances and new immunological functions. Immunol. Today 17: 481-486, 1996.
36. Weiss, A., and D. R. Littman. Signal transduction by lymphocyte antigen receptors. Cell 76: 263-274, 1994.
37. 2+. J. Immunol. 150: 5338-5349, 1994.
38. Zweifach, A., and R. S. Lewis. Calcium-dependent potentiation of store-operated calcium channels in T lymphocytes. J. Gen. Physiol. 107: 597-610, 1996.