Epitope analysis of insulin autoantibodies using recombinant Fab

Clinical and Experimental Immunology

Volumn 140, Issue 3, 2005, Pages 564-571

  Padoa, C J ^a   Crowther, N J ^a   Thomas, J W ^d   Hall, T R ^b   Bekris, L M ^b   Torn, C ^e   Landin Olsson, M ^e   Ortqvist, E ^c   Palmer, J P ^b   Lernmark, A ^b   Hampe, Christiane S ^b  

^a UNIVERSITY OF THE WITWATERSRAND   (South Africa)

^b UNIVERSITY OF WASHINGTON   (United States)

^c KAROLINSKA INSTITUTE   (Sweden)

^d VANDERBILT UNIVERSITY   (United States)

^e LUND UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Epitopes; Insulin autoantibody; Radioligand binding assay; Recombinant Fab; Type 1 diabetes

Indexed keywords

AUTOANTIBODY; COMPLEMENTARY DNA; EPITOPE; HUMAN INSULIN; IMMUNOGLOBULIN F(AB) FRAGMENT; IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOGLOBULIN LIGHT CHAIN; INSULIN ANTIBODY; INSULIN I 125; MESSENGER RNA; MONOCLONAL ANTIBODY; RADIOLIGAND; RECOMBINANT IMMUNOGLOBULIN F(AB) FRAGMENT; UNCLASSIFIED DRUG;

ADOLESCENT; ADULT; AMINO ACID SEQUENCE; ARTICLE; AUTOIMMUNE DISEASE; BINDING AFFINITY; CHILD; CLINICAL ARTICLE; DIABETES MELLITUS; ESCHERICHIA COLI; FEMALE; GENE EXPRESSION; HORMONE BINDING; HUMAN; IMMUNOGLOBULIN GENE; INSULIN DEPENDENT DIABETES MELLITUS; LIGAND BINDING; MALE; MOLECULAR CLONING; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ADOLESCENT; ADULT; AMINO ACID SEQUENCE; ANTIBODIES, MONOCLONAL; AUTOANTIBODIES; BASE SEQUENCE; CHILD; CHILD, PRESCHOOL; DIABETES MELLITUS, TYPE 1; EPITOPE MAPPING; EPITOPES; FEMALE; HUMANS; IMMUNOGLOBULIN FAB FRAGMENTS; INFANT; INSULIN; INSULIN ANTIBODIES; MALE; PREDIABETIC STATE; RECOMBINANT PROTEINS;

EID: 20444473243     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2249.2005.02802.x     Document Type: Article

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