Simultaneous kinetic characterization of multiple protein forms by top down mass spectrometry

Journal of the American Society for Mass Spectrometry

Volumn 16, Issue 7, 2005, Pages 1052-1059

  Zhai, Huili ^a   Dorrestein, Pieter C ^a   Chatterjee, Abhishek ^a   Begley, Tadhg P ^a   McLafferty, Fred W ^a  

^a Department of Obstetrics Gynecology   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOSYNTHESIS; FOURIER TRANSFORMS; IONIZATION; MASS SPECTROMETRY; MUTAGENESIS; REACTION KINETICS;

DERIVATIZATION; ELECTROSPRAY IONIZATION; ENZYME MODIFICATIONS; RADIOCHEMICAL ASSAYS;

PROTEINS;

CARBOXYLIC ACID DERIVATIVE; ENZYME; IMINE; ISOENZYME; ISOTOPE; MUTANT PROTEIN; PROTEIN; RIBONUCLEASE; RIBONUCLEASE A; THIAMINE PHOSPHATE; THIAZOLE DERIVATIVE;

ACCURACY; ARTICLE; BIOSYNTHESIS; BIOTRANSFORMATION; CHEMICAL BOND; DERIVATIZATION; ELECTROSPRAY MASS SPECTROMETRY; ENZYME MODIFICATION; ENZYME STABILITY; IONIZATION; ISOTOPE ANALYSIS; KINETICS; MASS SPECTROMETRY; MEASUREMENT; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; MOLECULAR STABILITY; MOLECULAR WEIGHT; MONITORING; PROTEIN DEPLETION; PROTEIN FOLDING; PROTEIN SYNTHESIS; RADIOCHEMISTRY; REACTION ANALYSIS; REACTION TIME; REDUCTION; STANDARD;

BACILLUS SUBTILIS; ESCHERICHIA COLI; ISOENZYMES; KINETICS; REPRODUCIBILITY OF RESULTS; RIBONUCLEASE, PANCREATIC; RIBONUCLEASES; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; THIAMINE TRIPHOSPHATE; THIAZOLES;

EID: 20444463181     PISSN: 10440305     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jasms.2005.02.016     Document Type: Article

References (29)

1. F.Y.L. Hsieh, X. Tong, T. Wachs, B. Ganem, J. Henion Kinetic Monitoring of Enzymatic Reactions in Real Time by Quantitative High-Performance Liquid Chromatography-Mass Spectrometry Anal. Biochem 229 1995 20 25
2. B. Bothner, R. Chavez, J. Wei, C. Strupp, Q. Phung, A. Schneemann, G. Siuzdak Monitoring Enzyme Catalysis with Mass Spectrometry J. Biol. Chem. 275 2000 13455 13459
3. X. Ge, T.L. Sirich, M.K. Beyer, H. Desaire, J.A. Leary A Strategy for Determination of Enzyme Kinetics Using Electrospray Ionization with an Ion Trap Mass Spectrometer Anal. Chem. 73 2001 5078 5082, and references cited therein.
4. S.A. Gerber, C.R. Scott, F. Turecek, M.H. Gelb Direct Profiling of Multiple Enzyme Activities in Human Cell Lysates by Affinity Chromatography/Electrospray Ionization Mass Spectrometry Application to Clinical Enzymology Anal. Chem. 73 2001 1651 1657
5. D.L. Zechel, L. Konermann, S.G. Withers, D.J. Douglas Pre-steady State Kinetic Analysis of an Enzymatic Reaction Monitored by Time-Resolved Electrospray Ionization Mass Spectrometry Biochemistry 37 1998 7664 7669
6. C.T. Houston, W.P. Taylor, T.S. Widlanski, J.P. Reilly Investigation of Enzyme Kinetics Using Quench-Flow Techniques with MALDI-TOF Mass Spectrometry Anal. Chem. 72 2000 3311 3319
7. M.B. Comisarow, A.G. Marshall Fourier Transform Ion Cyclotron Resonance Spectroscopy Chem. Phys. Lett. 25 1974 282 283
8. I.J. Amster Fourier Transform Mass Spectrometry J. Mass Spectrom. 31 1996 1325 1337
9. N.L. Kelleher, H.Y. Lin, G.A. Valaskovic, D.J. Aaserud, E.K. Fridriksson, F.W. McLafferty Top Down Versus Bottom Up Protein Characterization by Tandem High-Resolution Mass Spectrometry J. Am. Chem. Soc. 121 1999 806 812
10. Y. Ge, B.G. Lawhorn, M. ElNaggar, E. Strauss, J. Park, T.P. Begley, F.W. McLafferty Top Down Characterization of Larger Proteins (45 kDa) by Electron Capture Dissociation Mass Spectrometry J. Am. Chem. Soc. 124 2002 672 678
11. Y. Ge, M. ElNaggar, S.K. Sze, H. Oh, T.P. Begley, F.W. McLafferty, H. Boshoff, C.E. Barry Top Down Characterization of Secreted Proteins from Mycobacterium tuberculosis by Electron Capture Dissociation Mass Spectrometry J. Am. Soc. Mass Spectrum. 14 2003 253 261
12. V. Zabrouskov, L. Giacomelli, K.J. van Wijk, F.W. McLafferty A New Approach for Plant Proteomics Characterization of Chloroplast Proteins of Arabidopsis thaliana by Top Down Mass Spectrometry Mol. Cell. Proteom. 2 2003 1253 1260
13. G.A. Valaskovic, N.L. Kelleher, F.W. McLafferty Attomole Protein Characterization by Capillary Electrophoresis/Mass Spectrometry Science 273 1996 1199 1202
14. G. Xu, H. Zhai, M. Narayan, F.W. McLafferty, H.A. Scheraga Simultaneous Characterization of the Reductive Unfolding Pathways of RNase B Isoforms by Top Down Mass Spectrometry Chem. Biol. 11 2004 517 524
15. S.C. Beu, M.W. Senko, J.P. Quinn, F.M. Wampler, F.W. McLafferty Fourier-Transform Electrospray Instrumentation for Tandem High-resolution Mass Spectrometry of Large Molecules J. Am. Soc. Mass Spectrom. 4 1993 557 565
16. D.M. Horn, R.A. Zubarev, F.W. McLafferty Automated Reduction and Interpretation of High Resolution Electrospray Mass Spectra of Large Molecules J. Am. Soc. Mass. Spectrom. 11 2000 320 332
17. F. Jordan Current Mechanistic Understanding of Thiamin Diphosphate-Dependant Enzymatic Reactions Nat. Prod. Rep. 20 2003 184 201
18. J. Park, P.C. Dorrestein, H. Zhai, C. Kinsland, F.W. McLafferty, T.P. Begley Biosynthesis of the Thiazole Moiety of Thiamin Pyrophosphate (Vitamin B1) Biochemistry 42 2003 12430 12438
19. 1) The Early Steps Catalyzed by Thiazole Synthase J. Am. Chem. Soc. 126 2004 3091 3096
20. E.C. Settembre, P.C. Dorrestein, H. Zhai, A. Chatterjee, F.W. McLafferty, T.P. Begley, S.E. Ealick Thiamin Biosynthesis in Bacillus subtilis: Structure of the Thiazole Synthase/Sulfur Carrier Protein Complex Biochemstry 43 2004 11647 11657
21. B.A. Cerda, D.M. Horn, K. Breuker, F.W. McLafferty Sequencing of Specific Copolymer Oligomers by Electron-Capture-Dissociation Mass Spectrometry J. Am. Chem. Soc. 124 2002 9287 9291
22. A.G. Marshall, M.W. Senko, W. Li, M. Li, S. Dillon, S. Guan, T.M. Logan Protein Molecular Weight to 1 Da by 13C, 15N Double-Depletion and FT-ICR Mass Spectrometry J. Am. Chem. Soc. 119 1997 433 434
23. P.C. Dorrestein, H. Zhai, F.W. McLafferty, T.P. Begley The Biosynthesis of the Thiazole Phosphate Moiety of Thiamin The Sulfur Transfer Mediated by the Sulfur Carrier Protein ThiS Chem. Biol. 11 2004 1373
24. J.J. Pesavento, Y. Kim, G.K. Taylor, N.L. Kelleher Shotgun Annotation of Histone Modifications. A New Approach for Streamlined Characterization of Proteins by Top Down Mass Spectrometry J. Am. Chem. Soc. 126 2004 3386 3387
25. L.M. Hicks, S.E. O'Conner, M.T. Mazur, C.T. Walsh, N.L. Kelleher Mass Spectrometric Interrogation of Thioester-Bound Intermediates in the Initial Stages of Epothilone Biosynthesis Chem. Biol. 11 2004 327 335
26. M.T. Mazur, C.T. Walsh, N.L. Kelleher Site-Specific Observation of Acyl Intermediate Processing in Thiotemplate Biosynthesis by Fourier Transform Mass Spectrometry Biochemistry 42 2003 13393 13400
27. M. Narayan, G. Xu, D. Ripoll, H. Zhai, K. Breuker, C. Wanjalla, H.J. Ceung, A. Navon, E. Welker, F.W. McLafferty, H.A. Scheraga Dissimilarity in the Reductive Unfolding Pathways of Two Ribonuclease Homologues J. Mol. Biol. 338 2004 795 809
28. J. Xi, Y. Ge, C. Kinsland, F.W. McLafferty, T.P. Begley Biosynthesis of the Thiazole Moiety of Thiamin in Escherichia coli: Identification of an Acyldisulfide-Linked Protein-Protein Conjugate that is Functionally Analogous to the Ubiquitin/E1 Complex Proc. Natl. Acad. Sci. U.S.A. 98 2001 8513 8518
29. S.M. McLoughlin, N.L. Kelleher Kinetic and Regiospecific Interrogation of Covalent Intermediates in the Biosynthesis of Yersiniabactin J. Am. Chem. Soc. 126 2004 13265 13275