In situ photoactivation of a caged phosphotyrosine peptide derived from focal adhesion kinase temporarily halts lamellar extension of single migrating tumor cells

Journal of Biological Chemistry

Volumn 280, Issue 23, 2005, Pages 22091-22101

  Humphrey, David ^a   Rajfur, Zenon ^a   Vazquez, M Eugenio ^b   Scheswohl, Danielle ^a   Schaller, Michael D ^a   Jacobson, Ken ^a   Imperiali, Barbara ^b  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADHESION; AMINO ACIDS; BINDING ENERGY; CELLS; DISEASES; PHOTOCHEMICAL REACTIONS; SYNTHESIS (CHEMICAL); TUMORS;

CELLS SIGNALING; CYTOPLASM; FOCAL ADHESION KINASE (FAK); PHOTOACTIVATION;

ENZYME KINETICS;

FOCAL ADHESION KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOTYROSINE; PROTEIN SH2;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL MIGRATION; CONTROLLED STUDY; DISSOCIATION CONSTANT; EMBRYO; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LAMELLAR BODY; NONHUMAN; PEPTIDE SYNTHESIS; PHENOTYPE; PHOTOACTIVATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN STABILITY; RAT; SIGNAL TRANSDUCTION; TUMOR CELL; WESTERN BLOTTING;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; BINDING SITES; BINDING, COMPETITIVE; CELL ADHESION; CELL LINE, TUMOR; CELL MOVEMENT; CELL SURVIVAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FOCAL ADHESION KINASE 1; FOCAL ADHESION PROTEIN-TYROSINE KINASES; GLUTATHIONE TRANSFERASE; KINETICS; LIGHT; MODELS, CHEMICAL; PEPTIDES; PHOSPHORYLATION; PHOSPHOTYROSINE; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTEIN-TYROSINE KINASES; RATS; RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION; TIME FACTORS; TYROSINE;

EID: 20444439174     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M502726200     Document Type: Article

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