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Volumn 13, Issue 13, 2005, Pages 4279-4290

Design, synthesis and evaluation of carbazole derivatives as PPARα/γ dual agonists and antioxidants

(6) Kumar, Rakesh a Ramachandran, Uma a Srinivasan, Krishnamoorthy a Ramarao, Poduri a Raichur, Suryaprakash b Chakrabarti, Ranjan b

a NATIONAL INSTITUTE OF PHARMACEUTICAL EDUCATION AND RESEARCH NIPER (India)

b DR REDDY'S LABORATORIES LTD (India)

Author keywords

Antioxidant; Hydroxycarbazoles; Hypoglycemic; Lipid peroxidation; PPAR dual agonists; Transactivation

Indexed keywords

3 [4 [2 (4 METHOXYCARBAZOLE)ETHOXY]PHENYL] 2 ETHOXYPROPIONIC ACID; 3 [4 [2 (9H CARBAZOL 4 XYLOXY)ETHOXY]PHENYL] 2 ETHOXYPROPIONIC ACID; 3 [4 [2 (9H CARBAZOL 4 YLOXY)ETHOXY]PHENYL] 2 (1 METHYL 3 OXO 3 PHENYLPROPENYLAMINO)PROPIONIC ACID; 4 [2 (9H CARBAZOL 4 YLOXY)ETHOXY] 3 METHOXYBENZOIC ACID; ANTIOXIDANT; CARBAZOLE DERIVATIVE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR AGONIST; PIRINIXIC ACID; ROSIGLITAZONE; TROLOX C; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG DESIGN; DRUG SCREENING; DRUG SYNTHESIS; HUMAN; HUMAN CELL; MALE; MOUSE; NONHUMAN; RAT;

ANIMALS; ANTIOXIDANTS; BLOOD GLUCOSE; CARBAZOLES; CELLS, CULTURED; DIABETES MELLITUS, TYPE 2; DRUG DESIGN; HUMANS; HYPERLIPIDEMIAS; KIDNEY; LIPID PEROXIDATION; MALE; MICE; MICE, OBESE; PPAR ALPHA; PPAR GAMMA; RATS; RATS, SPRAGUE-DAWLEY; STRUCTURE-ACTIVITY RELATIONSHIP; TRANS-ACTIVATION (GENETICS); TRIGLYCERIDES;

ANIMALIA;

EID: 20344406220 PISSN: 09680896 EISSN: None Source Type: Journal
DOI: 10.1016/j.bmc.2005.04.018 Document Type: Article

Times cited : (28)

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