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Volumn 6, Issue 17, 1996, Pages 2121-2126

Non thiazolidinedione antihyperglycaemic agents. 1: α-Heteroatom substituted β-phenylpropanoic acids

Author keywords

[No Author keywords available]

Indexed keywords

2,4 THIAZOLIDINEDIONE DERIVATIVE; ANTIDIABETIC AGENT; BRL 48482; HYDROCINNAMIC ACID DERIVATIVE; SB 213068; STEROID RECEPTOR; TROGLITAZONE; UNCLASSIFIED DRUG;

EID: 0030567857     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/0960-894X(96)00383-6     Document Type: Article
Times cited : (59)

References (36)
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  • 3
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    • (b) Landsberg, L., Hypertension, 1992, 19 (Suppl. I), 161-166.
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  • 23
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    • International Patent Appl., Publication No. WO91/19702
    • During the course of our work we became aware of similar studies being conducted by the Pfizer group. Hulin, B., International Patent Appl., Publication No. WO91/19702, 1991.
    • (1991)
    • Hulin, B.1
  • 26
    • 85030269958 scopus 로고    scopus 로고
    • note
    • -1 diet) which reduces the area under the glucose tolerance curve by 25% relative to controls.
  • 27
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    • International Patent Appl., Publication No. WO93/21166
    • Haigh, D., International Patent Appl., Publication No. WO93/21166, 1993.
    • (1993)
    • Haigh, D.1
  • 28
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    • International Patent Appl., Publication No. W094/29285
    • Faller, A., International Patent Appl., Publication No. W094/29285, 1994.
    • (1994)
    • Faller, A.1
  • 29
    • 0343327796 scopus 로고
    • ed. Taylor, J. B., Pergamon
    • Hydrolysis of simple esters in vivo is known to be a facile process. Caldwell, J. and Mitchell, S. C. in Comprehensive Medicinal Chemistry, ed. Taylor, J. B., Pergamon, 1990, vol. 5, p. 151.
    • (1990) Comprehensive Medicinal Chemistry , vol.5 , pp. 151
    • Caldwell, J.1    Mitchell, S.C.2
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    • International Patent Appl., Publication No. WO94/01420
    • Haigh, D. and Sime, J. T., International Patent Appl., Publication No. WO94/01420, 1994.
    • (1994)
    • Haigh, D.1    Sime, J.T.2
  • 34
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    • note
    • -1 diet in ob/ob mice) was present at 145 pM. Competing compounds were dissolved in DMSO (concentration of DMSO did not exceed 0.1%). Binding was allowed to reach equilibrium by incubation for 18 hours at 4°C. Bound ligand was separated from free on mixed cellulose ester filters. Each assay was performed in triplicate.
  • 36
    • 0028354039 scopus 로고
    • Haigh, D., Tetrahedron, 1994, 50, 3177-3194.
    • (1994) Tetrahedron , vol.50 , pp. 3177-3194
    • Haigh, D.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.