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Volumn 46, Issue 27, 2005, Pages 4543-4546

Kinetic resolution by copper-catalyzed azide-alkyne cycloaddition

Author keywords

[No Author keywords available]

Indexed keywords

ALKYNE DERIVATIVE; AZIDE; COPPER;

EID: 20344406206     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2005.05.019     Document Type: Article
Times cited : (121)

References (25)
  • 18
    • 20344391794 scopus 로고    scopus 로고
    • See Supporting Information for details.
    • See Supporting Information for details.
  • 19
    • 20344363281 scopus 로고    scopus 로고
    • note
    • Nonlinear effects in mixed-ligand systems are certainly possible and are under investigation.
  • 20
    • 20344390628 scopus 로고    scopus 로고
    • note
    • 2NEt. The resulting solution was stored at 0-4°C for 24 h. The solvent was removed and the mixture was analyzed without purification to determine kinetic selectivity. When desired, pure components were obtained by silica gel column chromatography, eluting with hexanes to recover the azide and with a 10:1 hexanes:EtOAc to elute the product (14). Values of enantiomeric excess were determined by HPLC using a Chiralcel OD-H column


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.