Reduced interleukin-18 secretion in Brucella abortus 2308-infected murine peritoneal macrophages and in spleen cells obtained from B. abortus 2308-infected mice

Journal of Medical Microbiology

Volumn 54, Issue 6, 2005, Pages 527-531

  Fernández Lago, Luis ^a   Orduña, Antonio ^b   Vizcaíno, Nieves ^a  

^a UNIVERSITY OF SALAMANCA   (Spain)

^b UNIVERSITY OF VALLADOLID   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CD1 ANTIGEN; GAMMA INTERFERON; INTERLEUKIN 12; INTERLEUKIN 18; RECOMBINANT INTERLEUKIN 12; RECOMBINANT INTERLEUKIN 18;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; BACTERIAL VIRULENCE; BRUCELLA ABORTUS; BRUCELLOSIS; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; FEMALE; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; SPLEEN CELL; TH1 CELL;

ANIMALS; ANIMALS, OUTBRED STRAINS; BRUCELLA ABORTUS; BRUCELLOSIS; CELLS, CULTURED; DOWN-REGULATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; INTERFERON TYPE II; INTERLEUKIN-12; INTERLEUKIN-18; MACROPHAGES, PERITONEAL; MICE; SPLEEN; TIME FACTORS;

EID: 20344396599     PISSN: 00222615     EISSN: None     Source Type: Journal    
DOI: 10.1099/jmm.0.45936-0     Document Type: Article

References (24)

1. Araya, L. N., Elzer, P. H., Rowe, G. E., Enright, F. M. & Winter, A. J. (1989). Temporal development of protective cell-mediated and humoral immunity in BALB/c mice infected with Brucella abortus. J Immunol 143, 3330-3337.
2. Bohn, E., Sing, A., Zumbihl, R., Brielfeldt, C., Okamura, H., Kurimoto, M., Heesemann, J. & Autenrieth, I. B. (1998). IL-18 (IFN-γ-inducing factor) regulates early cytokine production in, and promotes resolution of, bacterial infection in mice. J Immunol 160, 299-307.
3. Elhofy, A. & Bost, K. (1999). Limited interleukin-18 response in Salmonella-infected murine macrophages and in Salmonella-infected mice. Infect Immun 67, 5021-5026.
4. Fernández-Lago, L., Rodriguez-Tarazona, E. & Vizcaino, N. (1999). Differential secretion of interleukin-12 (IL-12) subunits and heterodimeric IL-12p70 protein by CD-1 mice and murine macrophages in response to intracellular infection by Brucella abortus. J Med Microbiol 48, 1065-1073.
5. Gerdes, N., Sukhova, G. K., Libby, P., Reynolds, R. S., Young, J. L. & Schonbeck, U. (2002). Expression of interleukin (IL)-18 and functional IL-18 receptor on human vascular endothelial cells, smooth muscle cells, and macrophages: implications for atherogenesis. J Exp Med 195, 245-257.
6. Ghayur, T., Banerjee, S., Hugunin, M. & 11 other authors (1997). Caspase-1 processes IFN-gamma-inducing factor and regulates LPS-induced IFN-gamma production. Nature 386, 619-626.
7. Jiang, X. & Baldwin, C. L. (1993). Effects of cytokines on intracellular growth of Brucella abortus. Infect Immun 61, 124-134.
8. Joubier-Maurin, V., Boigegrain, R. A., Cloeckaert, A. & 8 other authors (2001). Major outer membrane protein Omp25 of Brucella suis is involved in inhibition of tumor necrosis factor alpha production during infection of human macrophages. Infect Immun 69, 4823-4830.
9. Lauw, F. N., Branger, J., Florquin, S., Speelman, P., van Deventer, S. J. H., Akira, S. & van der Poll, T. (2002). IL-18 improves the early antimicrobial host response to pneumococcal pneumonia. J Immunol 168, 372-378.
10. Mastroeni, P. S., Clare, S., Khan, S., Harrison, J. A., Hormaeche, C. E., Okamura, H., Kurimoto, M. & Dougan, G. (1999). Interleukin 18 contributes to host resistance and gamma interferon production in mice infected with virulent Salmonella typhimurium. Infect Immun 67, 478-483.
11. Neighbors, M., Xu, X., Barrat, F. J. & 7 other authors (2001). A critical role for interleukin 18 in primary and memory effector responses to Listeria monocytogenes that extend beyond its effects on interferon gamma production. J Exp Med 194, 343-354.
12. Netea, M. G., Kullberg, B. J., Verschueren, I. & van der Meer, J. W. (2000). Interleukin-18 induces production of proinflammatory cytokines in mice: no intermediate role for the cytokines of the tumor necrosis factor family and interleukin-1β. J Immunol 30, 3057-3060.
13. Ohkusu, K., Yoshimoto, T., Takeda, K., Ogura, T., Kashiwamura, S.-I., Iwakura, Y., Akira, S., Okamura, H. & Nakanishi, K. (2000). Potentiality of interleukin-18 as a useful reagent for treatment and prevention of Leishmania major infection. Infect Immun 68, 2449-2456.
14. Pasquali, P., Adone, R., Gasbarre, L. C., Pistola, C. & Ciuchini, F. (2001). Mouse cytokine profiles associated with Brucella abortus RB51 vaccination or B. abortus 2308 infection. Infect Immun 69, 6541-6544.
15. Pasquali, P., Adone, R., Gasbarre, L. C., Pistoia, C. & Ciuchini, F. (2002). Effect of exogenous interleukin-18 (IL-18) and IL-12 in the course of Brucella abortus 2308 infection in mice. Clin Diag Lab Immunol 9, 491-492.
16. Pizarro-Cerdá, J., Moreno, E., Sanguedolce, V., Mege, J. L. & Gorvel, J. P. (1998). Virulent Brucella abortus prevents lysosome fusion and is distributed within autophagosome-like compartments. Infect Immun 66, 2387-2392.
17. Schultz, M. J., Knapp, S., Florquin, S., Pater, J., Takeda, K., Akira, S. & van der Poll, T. (2003). Interleukin-18 impairs the pulmonary host response to Pseudomonas aeruginosa. Infect Immun 71, 1630-1634.
18. Stuyt, R. J., Netea, M. G., van Krieken, J. H., van der Meer, J. W. & Kullberg, B. J. (2004). Recombinant interleukin-18 protects against disseminated Candida albicans infection in mice. J Infect Dis 189, 1524-1527.
19. Sugawara, I., Yamada, H., Kaneko, H., Mizuno, S., Takeda, K. & Akira, S. (1999). Role of interleukin-18 (IL-18) in mycobacterial infection in IL-18-gene-disrupted mice. Infect Immun 67, 2585-2589.
20. Takeda, K., Tsutsui, H., Yoshimoto, T., Adachi, O., Yoshida, N., Kishimoto, T., Okamura, H., Nakanishi, K. & Akira, S. (1998). Defective NK cell activity and Th1 response in IL-18-deficient mice. Immunity 8, 383-390.
21. Vizcaíno, N., Chordi, A. & Fernández-Lago, L. (1991). Characterization of smooth Brucella lipopolysaccharides and polysaccharides by monoclonal antibodies. Res Microbiol 142, 971-978.
22. Yoshimoto, T., Nagai, N., Ohkusu, K., Ueda, H., Okamura, H. & Nakanishi, K. (1998). IL-12 up-regulates IL-18 receptor expression on T cells, Th1 cells, and B cells: synergism with IL-18 for IFN-γ production. J Immunol 161, 3400-3407.
23. Zhan, Y. & Cheers, C. (1995). Endogenous interleukin-12 is involved in resistance to Brucella abortus infection. Infect Immun 63, 1387-1390.
24. Zhan, Y., Yang, J. & Cheers, C. (1993). Cytokine response of T-cell subsets from Brucella abortus-infected mice to soluble Brucella proteins. Infect Immun 61, 2841-2847.