Virulent Brucella abortus prevents lysosome fusion and is distributed within autophagosome-like compartments

Infection and Immunity

Volumn 66, Issue 5, 1998, Pages 2387-2392

  Pizarro Cerdá, Javier ^a   Moreno, Edgardo ^a   Sanguedolce, Veronique ^b   Mege, Jean Louis ^b   Gorvel, Jean Pierre ^a  

^a INSERM   (France)

^b TIMONE HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CATHEPSIN D;

ARTICLE; AUTOPHAGY; BACTERIAL GROWTH; BACTERIAL VIRULENCE; BRUCELLA ABORTUS; BRUCELLOSIS; CONTROLLED STUDY; ENDEMIC DISEASE; HELA CELL; HUMAN; HUMAN CELL; LYSOSOME; NONHUMAN; PHAGOSOME; PRIORITY JOURNAL; STRAIN DIFFERENCE;

BRUCELLA ABORTUS;

EID: 0031899678     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.66.5.2387-2392.1998     Document Type: Article

References (39)

1. Anderson, T. D., and N. F. Cheville. 1986. Ultrastructural morphometric analysis of Brucella abortus-infected trophoblasts in experimental placentitis. Bacterial replication occurs in rough endoplasmic reticulum. Am. J. Pathol. 124:226-237.
2. Aragón, V. R., R. Díaz, E. Moreno, and I. Moriyón. 1996. Characterization of Brucella abortus and Brucella melitensis native haptens as outer membrane O-type polysaccharides independent from the smooth lipopolysaccharide. J. Bacteriol. 178:1070-1079.
3. Araya, L. N., P. H. Elzer, G. E. Rowe, F. M. Enright, and A. J. Winter. 1989. Temporal development of protective cell-mediated and humoral immunity in BALB/c mice infected with Brucella abortus. J. Immunol. 143:3330-3337.
4. Baldwin, C. L., and A. J. Winter. 1994. Macrophages and Brucella. Immunol. Ser. 60:363-380.
5. Blommaart, E. F. C., U. Krause, J. P. M. Shellens, H. Vreeling-Sindelarova, and A. J. Meijer. 1997. The phosphatidylinositol 3-kinase inhibitors wortmannin and LY294002 inhibit autophagy in isolated rat hepatocytes. Eur. J. Biochem. 243:240-246.
6. Clemens, D. L. 1996. Characterization of the Mycobacterium tuberculosis phagosome. Trends Microbiol. 4:113-118.
7. Clemens, D. L., and M. A. Horwitz. 1995. Characterization of the Mycobacterium tuberculosis phagosome and evidence that phagosomal maturation is inhibited. J. Exp. Med. 181:257-270.
8. de Chastellier, C., T. Lang, and L. Thilo. 1995. Phagocytic processing of the macrophage endoparasite, Mycobacterium avium, in comparison to phagosomes which contain Bacillus subtilis or latex beads. Eur. J. Cell Biol. 68: 167-182.
9. Detilleux, P. G., B. L. Deyoe, and N. F. Cheville. 1990. Entry and intracellular localization of Brucella spp. in Vero cells: fluorescence and electron microscopy. Vet. Pathol. 27:317-328.
10. Detilleux, P. G., B. L. Deyoe, and N. F. Cheville. 1990. Penetration and intracellular growth of Brucella abortus in nonphagocytic cells in vitro. Infect. Immun. 58:2320-2328.
11. Detilleux, P. G., B. L. Deyoe, and N. F. Cheville. 1991. Effect of endocytic and metabolic inhibitors on the internalization and intracellular growth of Brucella abortus in Vero cells. Am. J. Vet. Res. 52:1658-1664.
12. Dunn, W. A. 1994. Autophagy and related mechanisms of lysosome-mediated protein degradation. Trends Cell Biol. 4:139-143.
13. Elsinghorst, E. A. 1994. Measurement of invasion by gentamicin resistance. Methods Enzymol. 236:405-420.
14. Enright, F. M. 1990. The pathogenesis and pathobiology of Brucella infection in domestic animals. Antigens of Brucella, p. 301-320. In K. Nielsen and B. Duncan (ed.), Animal brucellosis. CRC Press, Inc, Boca Raton, Fla.
15. Freer, E., E. Moreno, I. Moriyon, J. Pizarro-Cerdá, A. Weintraub, and J. P. Gorvel. 1996. Brucella-Salmonella lipopolysaccharide chimeras are less permeable to hydrophobic probes and more sensitive to cationic peptides and EDTA than their native Brucella sp. counterparts. J. Bacteriol. 178:5867-5876.
16. Frenchick, P. J., R. J. F. Markham, and A. H. Cochrane. 1985. Inhibition of phagosome-lysosome fusion in macrophages by soluble extracts of virulent Brucella abortus. Am. J. Vet. Res. 46:332-335.
17. Halling, S. M., P. G. Detilleux, F. M. Tatum, B. A. Judge, and J. E. Mayfield. 1991. Deletion of the BCSP31 gene of Brucella abortus by replacement. Infect. Immun. 59:3863-3868.
18. Harmon, B. G., L. G. Adams, and M. Frey. 1988. Survival of rough and smooth strains of Brucella abortus in bovine mammary gland macrophages. Am. J. Vet. Res. 49:1092-1097.
19. Horwitz, M. A. 1983. The Legionnaires' disease bacterium (Legionella pneumophila) inhibits phagosome-lysosome fusion in human monocytes. J. Exp. Med. 158:2108-2126.
20. Horwitz, M. A., and F. R. Maxfield. 1984. Legionella pneumophila inhibits acidification of its phagosome in human monocytes. J. Cell Biol. 99:1936-1943.
21. Jones, S. M., and A. J. Winter. 1992. Survival of virulent and attenuated strains of Brucella abortus in normal and gamma interferon-activated murine peritoneal macrophages. Infect. Immun. 60:3011-3014.
22. Kreutzer, D. L., L. A. Dreyfus, and D. C. Robertson. 1979. Interaction of polymorphonuclear leukocytes with smooth and rough strains of Brucella abortus. Infect. Immun. 23:737-742.
23. Liautard, J. P. 1996. Interactions between professional phagocytes and Brucella spp. Microbiologia 12:197-206.
24. Martínez de Tejada, G., J. Pizarro-Cerdá, E. Moreno, and I. Moriyón. 1995. The outer membranes of Brucella spp. are resistant to bactericidal cationic peptides. Infect. Immun. 63:3054-3061.
25. Méresse, S., J. P. Gorvel, and P. Chavrier. 1995. The GTPase rab7 is involved in the transport between late endosomes and lysosomes. J. Cell Sci. 108:3349-3358.
26. Meyer, M. E. 1990. Evolution development and taxonomy of the genus Brucella, p. 12-35. In L. G. Adams (ed.), Advances in brucellosis research. Texas A & M University Press, College Station.
27. Price, R. E., J. W. Templeton, and L. G. Adams. 1990. Survival of smooth, rough and transposon mutant strains of Brucella abortus in bovine mammary macrophages. Vet. Immunol. Immunopathol. 26:353-365.
28. Rasool, O., E. Freer, E. Moreno, and C. Jarstrand. 1992. Effect of Brucella abortus lipopolysaccharide on oxidative metabolism and lysozyme release by human neutrophils. Infect. Immun. 60:1699-1702.
29. Riley, L. K., and D. C. Robertson. 1984. Brucellacidal activity of human and bovine polymorphonuclear leukocyte granule extracts against smooth and rough strains of Brucella abortus. Infect. Immun. 46:231-236.
30. Rojas, N., E. Freer, A. Weintraub, M. Ramirez, S. Lind, and E. Moreno. 1994. Immunochemical identification of Brucella abortus lipopolysaccharide epitopes. Clin. Diagn. Lab. Immunol. 1:206-213.
31. Seglen, P. O., and P. B. Gordon. 1982. 3-Methyladenine: specific inhibitor of autophagic/lysosomal protein degradation in isolated rat hepatocytes. Proc. Natl. Acad. Sci. USA 79:1889-1892.
32. Schworer, C. M., K. A. Shiffer, and G. E. Mortimore. 1981. Quantitative relationship between autophagy and proteolysis during graded amino acid deprivation in perfused rat liver. J. Biol. Chem. 256:7652-7658.
33. Smith, H., and R. B. Fitzgeorge. 1964. The effect of opsonization with antiserum in the survival of Brucella abortus within bovine phagocytes. Br. J. Exp. Pathol. 45:174-180.
34. Smith, L. D., and T. A. Ficht. 1990. Pathogenesis of Brucella. Crit. Rev. Microbiol. 17:209-230.
35. Sperry, J. F., and D. C. Robertson. 1975. Erythritol catabolism by Brucella abortus. J. Bacteriol. 121:619-630.
36. Stevens, M. G., S. C. Olsen, G. W. Pugh, Jr., and M. V. Palmer. 1994. Immune and pathologic responses in mice infected with Brucella abortus 19, RB51, or 2308. Infect. Immun. 62:3206-3212.
37. Sturgill-Koszycki, S., P. H. Schlesinger, P. Chakraborty, P. L. Haddix, H. L. Collins, A. K. Fok, R. D. Allen, S. L. Gluck, J. Heuser, and D. G. Russell. 1994. Lack of acidification in Mycobacterium phagosomes produced by exclusion of the vesicular proton-ATPase. Science 263:678-681.
38. Swanson, M. S., and R. R. Isberg. 1995. Association of Legionella pneumophila with the macrophage endoplasmic reticulum. Infect. Immun. 63:3609-3620.
39. Trujillo, I. Z., A. N. Zavala, J. G. Caceres, and C. Q. Miranda. 1994. Brucellosis. Infect. Dis. Clin. North Am. 8:225-241.