Insulin-like growth factor-I protects granule neurons from apoptosis and improves ataxia in weaver mice

Journal of Neuroscience Research

Volumn 80, Issue 4, 2005, Pages 481-490

  Zhong, Jin ^a   Deng, Jixian ^b   Phan, Jennifer ^a   Dlouhy, Stephen ^a   Wu, Huangbing ^a   Yao, Weiguo ^a   Ye, Ping ^c   D'Ercole, A Joseph ^c   Lee, Wei Hua ^a,d  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b BEIJING INSTITUTE OF BIOTECHNOLOGY   (China)

^c UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^d INDIANA UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Granule neurons; IGF I; Potassium channel; Weaver mice

Indexed keywords

CASPASE 3; POTASSIUM CHANNEL; PROTEIN KINASE B; SOMATOMEDIN BINDING PROTEIN 5; SOMATOMEDIN C;

ANIMAL BEHAVIOR; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ATAXIA; CELL CULTURE; CELL DIFFERENTIATION; CELL SURVIVAL; CEREBELLUM CORTEX; DEGENERATIVE DISEASE; ENZYME ACTIVITY; FEMALE; GENE; GIRK2 GENE; GRANULE CELL; HUMAN; IGF I TRANSGENE; MALE; MOUSE; MOUSE STRAIN; NERVE CELL; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; TRANSGENE; TRANSGENIC MOUSE;

AGE FACTORS; ANIMALS; ANIMALS, NEWBORN; APOPTOSIS; ATAXIA; BEHAVIOR, ANIMAL; BROMODEOXYURIDINE; CASPASE 3; CASPASES; CELL COUNT; CEREBELLUM; DNA POLYMERASE I; GENE EXPRESSION REGULATION, DEVELOPMENTAL; IN SITU HYBRIDIZATION; INSULIN-LIKE GROWTH FACTOR I; MICE; MICE, NEUROLOGIC MUTANTS; MICE, TRANSGENIC; MOTOR ACTIVITY; NEURONS; PSYCHOMOTOR PERFORMANCE;

EID: 20344375969     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/jnr.20490     Document Type: Article

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