A high-throughput chemotaxis assay for pharmacological characterization of chemokine receptors: Utilization of U937 monocytic cells

Journal of Pharmacological and Toxicological Methods

Volumn 51, Issue 2, 2005, Pages 105-114

  Ott, Thomas R ^a   Pahuja, Anil ^a   Lio, Francisco M ^a   Mistry, Monica S ^a   Gross, Molly ^a   Hudson, Sarah C ^a   Wade, Warren S ^a   Simpson, Pedro B ^a   Struthers, R Scott ^a   Alleva, David G ^a  

^a NEUROCRINE BIOSCIENCES INC   (United States)

Author keywords

CCR7; Cell migration; Chemokine antagonist; High throughput chemotaxis; Human; Leukocyte; Methods; Site directed mutagenesis

Indexed keywords

ALANINE; ALPHA CHEMOKINE; CALCIUM; CHEMOKINE RECEPTOR; CHEMOKINE RECEPTOR CCR7; MACROPHAGE INFLAMMATORY PROTEIN 3BETA;

AMINO ACID SUBSTITUTION; ARTICLE; CALCIUM MOBILIZATION; CELL STRAIN; CELL STRAIN U 937; CONTROLLED STUDY; FLUORESCENCE ANALYSIS; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; LEUKOCYTE CULTURE; LEUKOCYTE ROLLING; LIGAND BINDING; LYMPHOMA CELL LINE; RECEPTOR INTRINSIC ACTIVITY; SITE DIRECTED MUTAGENESIS;

TRIXIS;

EID: 20244380464     PISSN: 10568719     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vascn.2004.10.001     Document Type: Article

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