Mobilization of endothelial and hematopoietic stem and progenitor cells by adenovector-mediated elevation of serum levels of SDF-1, VEGF, and angiopoietin-1

Annals of the New York Academy of Sciences

Volumn 938, Issue , 2001, Pages 36-47

  Moore, M A S ^a   Hattori, K ^a   Heissig, B ^a   Shieh, J H ^a   Dias, S ^b   Crystal, R G ^b   Rafii, S ^b  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

Angioblast; Chemokine; Endothelium; Hematopoiesis; Stem cell

Indexed keywords

ANGIOPOIETIN 1; CD34 ANTIGEN; CHEMOKINE; CHEMOKINE RECEPTOR CXCR4; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; STROMAL CELL DERIVED FACTOR 1; VASCULOTROPIN; VASCULOTROPIN RECEPTOR; VIRUS VECTOR;

ADENOVIRUS; ANIMAL CELL; ANIMAL EXPERIMENT; B LYMPHOCYTE; BONE MARROW; CELL MOTILITY; CHEMOKINESIS; CHEMOTAXIS; COLONY FORMING UNIT S; CONFERENCE PAPER; CONTROLLED STUDY; CYTOKINE RELEASE; ENDOTHELIUM CELL; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL; LEUKOCYTOSIS; MACROPHAGE; MEGAKARYOCYTE; MONOCYTE; MOUSE; NONHUMAN; T LYMPHOCYTE; THROMBOCYTE;

EID: 20244375370     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.2001.tb03572.x     Document Type: Conference Paper

References (18)

1. The chemokine SDF-1 is a chemoattractant for human CD34+ hematopoietic progenitor cells and provides a new mechanism to explain the mobilization of CD34+ progenitors to peripheral blood
2. The chemokine receptor CXCR-4 is expressed on CD34+ hematopoietic progenitors and leukemic cells and mediates transendothelial migration induced by stromal cell-derived factor-1
3. Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1
4. Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development
5. Chemotaxis of primitive hematopoietic cells in response to stromal cell-derived factor-1
6. Dependence of human stem cell engraftment and repopulation of NOD/SCID mice on CXCR4
7. Adenovector-mediated expression of human thrombopoietin cDNA in immune-compromised mice: Insights into the pathophysiology of osteomyelofibrosis
8. Plasma elevation of stromal derived factor-1 induces mobilization of mature and immature hematopoietic progenitor and stem cells
9. Expression of VEGFR-2 and AC133 by circulating human CD34(+) cells identifies a population of functional endothelial precursors
10. KDR receptor: A key marker defining hematopoietic stem cells
11. Angiopoietin-1 induces sprouting angiogenesis in vitro
12. Protein, nucleotide chemotactic properties of angiopoietin-1 and -2, ligands for the endothelial-specific receptor tyrosine kinase Tie2
13. VEGF and angiopoietin-1 stimulate post-natal hematopoiesis by recruitment of hematopoietic stem and progenitor cells
14. Leakage-resistant blood vessels in mice transgenically overexpressing angiopoietin-1
15. Angiopoietin-1 protects the adult vasculature against plasma leakage
16. Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice
17. Migration of human monocytes in response to vascular endothelial growth factor (VEGF) is mediated via the VEGF receptor flt-1
18. Hematopoietic stem cells express Tie-2 receptor in the murine fetal liver