Experimental study on in vivo optical and radionuclide imaging in small animals

IEEE Transactions on Nuclear Science

Volumn 52, Issue 1 I, 2005, Pages 205-209

  Autiero, M ^a   Celentano, L ^a   Cozzolino, R ^a   Laccetti, P ^a   Marotta, M ^a   Mettivier, G ^a   Montesi, M C ^a   Riccio, P ^a   Roberti, G ^a   Russo, P ^a  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

Fluorescence; Nuclear imaging; Optical imaging; Radiation imaging

Indexed keywords

CELLS; CHARGE COUPLED DEVICES; FLUORESCENCE; GAMMA RAYS; LASERS; PHOTONS; RADIATION; RADIOISOTOPES; TUMORS;

NUCLEAR IMAGING; OPTICAL IMAGING; PINHOLE IMAGING SYSTEMS; RADIATION IMAGING;

MEDICAL IMAGING;

EID: 20244373776     PISSN: 00189499     EISSN: None     Source Type: Journal    
DOI: 10.1109/TNS.2004.843095     Document Type: Article

References (22)

1. L. Celentano et al., "Preliminary tests of a prototype system for optical and radionuclide imaging in small animals," IEEE Trans. Nucl. Sci, vol. 50, no. 5, pp. 1693-1701, Oct. 2005.
2. M. Campbell et al., "A readout chip for a 64 × 64 pixel matrix with 15-bit single photon counting," IEEE Trans. Nucl. Sci, vol. 45, no. 3, pp. 751-753, Jun. 1998.
3. E. Bertolucci et al., "Preliminary test of an imaging probe for nuclear medicine using hybrid pixel detectors. Presented at 3rd international workshop on radiation imaging detectors," Nucl. Instr. Meth. A, vol. 487, pp. 193-201, 2002.
4. X. Llopart et al., "Medipix2, a 64 k readout chip with 55 μm square elements working in single photon counting mode," IEEE Trans. Nucl. Sci, vol. 49, no. 5, pp. 2279-2283, Oct. 2002.
5. D. San Segundo Bello et al., "Design of an interface board for the control and DAQ of the Medipix2 chip," Nucl. Instr. Meth. A, vol. 509, pp. 164-170, 2003.
6. M. Conti et al., "Preliminary test of Medisoft 4: A control software for the Medipix2 readout chip," IEEE Trans. Nucl. Sci, vol. 50, no. 4, pp. 869-877, Aug. 2003.
7. M. Chmeissani et al., "First experimental tests with a CdTe photon counting pixel detector hybridized with a Medipix2 readout chip," IEEE Trans. Nucl. Sci., vol. 51, no. 5, pp. 2379-2385, Oct. 2004.
8. S. J. Lewis et al., "Small animal imaging: Current technology and perspectives for oncological imaging," Eur. J. Cancer, vol. 38, pp. 2173-2188, 2002.
9. R. Weissleder, "Scaling down imaging: Molecular mapping of cancer in mice," Nature Rew., vol. 2, pp. 11-18, 2002.
10. P. A. Scourides et al., "Nature of the tumor-localizing components of haematoporphyrin derivatives," Cancer Res., vol. 47, pp. 3439-3445, 1987.
11. W. G. Roben et al., "Cellular uptake and subcellular localization of mono-L-aspartyl chlorin e6, chloro-aluminum sulfonated phth, and phthalocyanine, and Photofrin II," Laser Surg. Med., vol. 9, pp. 90-101, 1989.
12. A. A. Rosenkranz et al., "Targeted intracellular delivery of photosensitizers to enhance photodynamic efficiency," Immunol. Cell Biol., vol. 78, pp. 452-464, 2000.
13. S. Gupta et al., "Cellular uptake, localization and photodynamic effect of haematoporphyrin derivative in human glioma and squamous carcinoma cell lines," J. Photochem. Photobiol. B, Biology, vol. 69, pp. 107-120, 2003.
14. J. S. Hill et al., "Selective uptake of hematoporphyrin derivatives into human cerebral glioma," Neurosurgery, vol. 26, pp. 248-254, 1990.
15. V. X. Yang et al., "A multi spectral fluorescence imaging system: Design and initial clinical tests in intra-operative Photofrin-photodynamic therapy of brain tumors," Lasers Surg. Med., vol. 32, pp. 224-232, 2003.
16. D. L. Prout et al., "Detector concept for OPET, a combined PET and optical imaging system," presented at the Nuclear Science Symposium and Medical Imaging Conf., Portland, OR, Oct. 20-24, 2003.
17. M. L. Chiu et al., "Effect of mitochondrial and plasma membrane potentials on accumulation of Hexakis (2-methoxyisobutylisonitrile) technetium in cultured mouse fibroblasts," J. Nucl. Med., vol. 31, pp. 1646-1653, 1990.
18. S. D. Vecchio et al., "Fractional retention of Tc-99m-Sestamibi as an index of P-glycoprotein expression in untreated breast cancer patients," J. Nuc. Med., vol. 38, pp. 1348-1351, 1997.
19. L. Kostakoglu et al., "Clinical validation of the influence of P-glycoprotein on Tc-99m-sestamibi uptake in malignant tumors," J Nucl. Med., vol. 38, pp. 1003-1008, 1997.
20. 99mTc-MIBI imaging as a predictor of therapy response in osteosarcoma compared with multidrug resistance-associated protein and p-glycoprotein expression," J. Nucl. Med., vol. 44, pp. 1394-1401, 2003.
21. I. Foldes et al., "Comparative scanning of thyroid nodules with technetium-99m pertechnetate and technetium-99m methoxyisobutylisonitrile," Eur. J. Nucl. Med., vol. 20, pp. 330-333, 1993.
22. G. Mettivier et al., "Design of a compact gamma camera with semiconductor hybrid pixel detectors: imaging tests with a pinhole collimator," Nucl. Instr. Meth. A, vol. 509, pp. 321-327, 2003.