Mucosal immunity in mice immunized with HIV-1 peptide conjugated to Brucella abortus

Vaccine

Volumn 20, Issue 9-10, 2002, Pages 1445-1450

  Golding, Basil ^a   Eller, Nancy ^a   Levy, Lily ^a   Beining, Paul ^a   Inman, John ^b   Matthews, Natasha ^a   Scott, Dorothy E ^a   Golding, Hana ^a  

^a CENTER FOR BIOLOGICS EVALUATION AND RESEARCH   (United States)

^b NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

Brucella abortus; HIV 1; Mucosal immunity

Indexed keywords

GAMMA INTERFERON; NEUTRALIZING ANTIBODY; PEPTIDE; VIRUS PROTEIN; VIRUS VACCINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRUCELLA ABORTUS; CONTROLLED STUDY; CYTOKINE RELEASE; FEMALE; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNIZATION; MOUSE; MUCOSA; MUCOSAL IMMUNITY; NONHUMAN; PRIORITY JOURNAL; PROGENY; SEXUALITY; T LYMPHOCYTE; VIRUS ENVELOPE; VIRUS TRANSMISSION;

AIDS VACCINES; ANIMALS; BRUCELLA ABORTUS; FEMALE; HIV ANTIBODIES; HIV-1; IMMUNITY, MUCOSAL; IMMUNIZATION; INTERFERON TYPE II; MICE; MICE, INBRED BALB C; T-LYMPHOCYTES, CYTOTOXIC; VACCINES, CONJUGATE; VIRAL ENVELOPE PROTEINS;

EID: 0037203915     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0264-410X(01)00477-7     Document Type: Article

References (11)

1. Immunological abnormalities in the acquired immunodeficiency syndrome
2. Production of a novel antigen by conjugation of HIV-1 to Brucella abortus: Studies of immunogenicity, isotype analysis, T cell dependency and syncytia inhibition
3. +T cell depletion
4. + cell-depleted BALB/c mice
5. Brucella abortus stimulates human T cells from uninfected and infected individuals to secrete IFNγ
6. + T cells express Th1-like cytokine mRNA and proteins following in vitro stimulation with heat-inactivated Brucella abortus
7. Lipopolysaccharide from Brucella abortus is less toxic than lipopolysaccharide from E. coli, suggesting the possible use of B. abortus as a carrier in vaccines
8. Lipopolysaccharide from Brucella abortus behaves as a T cell independent type 1 carrier in murine antigen-specific antibody responses
9. Inhibition of primary and recall allergen-specific Th2-mediated responses by a Th1 stimulus
10. Counting antigen-specific CD8 T cells: A re-evaluation of bystander activation during viral infection
11. IgG3 from polyclonal HIV immune globulin (HIVIG) is more potent than other subclasses in neutralizing HIV-1: Preferential HIV-1 neutralization by the IgG3 antibody subclass in HIV immune globulin