-
1
-
-
0036845563
-
Polymorphisms in the promoter of the human APP gene: Functional evaluation and allele frequencies in Alzheimer disease
-
Athan ES, Lee JH, Arriaga A, Mayeux RP, Tycko B. 2002. Polymorphisms in the promoter of the human APP gene: functional evaluation and allele frequencies in Alzheimer disease. Arch Neurol 59:1793-1799.
-
(2002)
Arch Neurol
, vol.59
, pp. 1793-1799
-
-
Athan, E.S.1
Lee, J.H.2
Arriaga, A.3
Mayeux, R.P.4
Tycko, B.5
-
2
-
-
0033654196
-
Candidate genes showing no evidence for association or linkage with Alzheimer's disease using family-based methodologies
-
Bertram L, Blacker D, Crystal A, Mullin K, Keeney D, Jones J, Basu S, Yhu S, Guenette S, McInnis M, Go R, Tanzir R. 2000. Candidate genes showing no evidence for association or linkage with Alzheimer's disease using family-based methodologies. Exp Gerontol 35:1353-1361.
-
(2000)
Exp Gerontol
, vol.35
, pp. 1353-1361
-
-
Bertram, L.1
Blacker, D.2
Crystal, A.3
Mullin, K.4
Keeney, D.5
Jones, J.6
Basu, S.7
Yhu, S.8
Guenette, S.9
McInnis, M.10
Go, R.11
Tanzir, R.12
-
3
-
-
0034610019
-
Characterization of an apoptosis inhibitory domain at the C-termini of FE65-like protein
-
Cao H, Pratt N, Mattison J, Zhao Y, Chang NS. 2000. Characterization of an apoptosis inhibitory domain at the C-termini of FE65-like protein. Biochem Biophys Res Commun 276:843-850.
-
(2000)
Biochem Biophys Res Commun
, vol.276
, pp. 843-850
-
-
Cao, H.1
Pratt, N.2
Mattison, J.3
Zhao, Y.4
Chang, N.S.5
-
4
-
-
0346435103
-
Generation of the beta-amyloid peptide and the amyloid precursor protein C-terminal fragment gamma are potentiated by FE65L1
-
Chang Y, Tesco G, Jeong WJ, Lindsley L, Eckman EA, Eckman CB, Tanzi RE, Guenette SY. 2003. Generation of the beta-amyloid peptide and the amyloid precursor protein C-terminal fragment gamma are potentiated by FE65L1. J Biol Chem 278:51100-51107.
-
(2003)
J Biol Chem
, vol.278
, pp. 51100-51107
-
-
Chang, Y.1
Tesco, G.2
Jeong, W.J.3
Lindsley, L.4
Eckman, E.A.5
Eckman, C.B.6
Tanzi, R.E.7
Guenette, S.Y.8
-
5
-
-
0242500800
-
A risk for early-onset Alzheimer's disease associated with the APBB1 gene (FE65) intron 13 polymorphism
-
Cousin E, Mannequin D, Ricard S, Mace S, Genin E, Chansac C, Brice A, Dubois B, Frebourg T, Mercken L, Benavides J, Pradier L, Campion D, Delueze JF. 2003. A risk for early-onset Alzheimer's disease associated with the APBB1 gene (FE65) intron 13 polymorphism. Neurosci Lett 342:5-8.
-
(2003)
Neurosci Lett
, vol.342
, pp. 5-8
-
-
Cousin, E.1
Mannequin, D.2
Ricard, S.3
Mace, S.4
Genin, E.5
Chansac, C.6
Brice, A.7
Dubois, B.8
Frebourg, T.9
Mercken, L.10
Benavides, J.11
Pradier, L.12
Campion, D.13
Delueze, J.F.14
-
6
-
-
0030823158
-
Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. A meta-analysis
-
APOE and Alzheimer Disease Meta Analysis Consortium
-
Farrer LA, Cupples LA, Haines JL, Hyman B, Kukull WA, Mayeux R, Myers RH, Pericak-Vance MA, Risch N, van Duijn CM. 1997. Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer Disease Meta Analysis Consortium. JAMA 278:1349-1356.
-
(1997)
JAMA
, vol.278
, pp. 1349-1356
-
-
Farrer, L.A.1
Cupples, L.A.2
Haines, J.L.3
Hyman, B.4
Kukull, W.A.5
Mayeux, R.6
Myers, R.H.7
Pericak-Vance, M.A.8
Risch, N.9
Van Duijn, C.M.10
-
7
-
-
0034090681
-
High-throughput SNP allele-frequency determination in pooled DNA samples by kinetic PCR
-
Germer S, Holland MJ, Higuchi R. 2000. High-throughput SNP allele-frequency determination in pooled DNA samples by kinetic PCR. Genome Res 10:258-266.
-
(2000)
Genome Res
, vol.10
, pp. 258-266
-
-
Germer, S.1
Holland, M.J.2
Higuchi, R.3
-
8
-
-
0021256895
-
Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein
-
Glenner GG, Wong CW. 1984. Alzheimer's disease: initial report of the purification and characterization of a novel cerebrovascular amyloid protein. Biochem Biophys Res Commun 120:885-890.
-
(1984)
Biochem Biophys Res Commun
, vol.120
, pp. 885-890
-
-
Glenner, G.G.1
Wong, C.W.2
-
9
-
-
0026088977
-
Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease
-
Goate A, Chartier-Harlin MC, Mullan M, Brown J, Crawford F, Fidani L, Giuffra L, Haynes A, Irving N, James L, Mant R, Newton P, Rooke K, Roques P, Talbot C, Pericak-Vance M, Roses A, Williamson R, Rossor M, Owen M, Hardy J. 1991. Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease. Nature 349:704-706.
-
(1991)
Nature
, vol.349
, pp. 704-706
-
-
Goate, A.1
Chartier-Harlin, M.C.2
Mullan, M.3
Brown, J.4
Crawford, F.5
Fidani, L.6
Giuffra, L.7
Haynes, A.8
Irving, N.9
James, L.10
Mant, R.11
Newton, P.12
Rooke, K.13
Roques, P.14
Talbot, C.15
Pericak-Vance, M.16
Roses, A.17
Williamson, R.18
Rossor, M.19
Owen, M.20
Hardy, J.21
more..
-
10
-
-
0029746156
-
Association of a novel human FE65-like protein with the cytoplasmic domain of the beta-amyloid precursor protein
-
Guenette SY, Chen J, Jondro PD, Tanzi RE. 1996. Association of a novel human FE65-like protein with the cytoplasmic domain of the beta-amyloid precursor protein. Proc Natl Acad Sci USA 93:10832-10837.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 10832-10837
-
-
Guenette, S.Y.1
Chen, J.2
Jondro, P.D.3
Tanzi, R.E.4
-
11
-
-
0344604494
-
hFE65L influences amyloid precursor protein maturation and secretion
-
Guenette SY, Chen J, Ferland A, Haass C, Capell A, Tanzi RE. 1999. hFE65L influences amyloid precursor protein maturation and secretion. J Neurochem 73:985-993.
-
(1999)
J Neurochem
, vol.73
, pp. 985-993
-
-
Guenette, S.Y.1
Chen, J.2
Ferland, A.3
Haass, C.4
Capell, A.5
Tanzi, R.E.6
-
12
-
-
0034672331
-
Evidence against association of the FE65 gene (APBB1) intron 13 polymorphism in Alzheimer's patients
-
Guenette SY, Bertram L, Crystal A, Bakondi B, Hyman BT, Rebeck GW, Tanzi RE, Blacker D. 2000. Evidence against association of the FE65 gene (APBB1) intron 13 polymorphism in Alzheimer's patients. Neurosci Lett 296:17-20.
-
(2000)
Neurosci Lett
, vol.296
, pp. 17-20
-
-
Guenette, S.Y.1
Bertram, L.2
Crystal, A.3
Bakondi, B.4
Hyman, B.T.5
Rebeck, G.W.6
Tanzi, R.E.7
Blacker, D.8
-
13
-
-
0031710443
-
The human FE65 gene: Genomic structure and an intronic biallelic polymorphism associated with sporadic dementia of the Alzheimer type
-
Hu Q, Kukull WA, Bressler SL, Gray MD, Cam JA, Larson EB, Martin GM, Deeb SS. 1998. The human FE65 gene: genomic structure and an intronic biallelic polymorphism associated with sporadic dementia of the Alzheimer type. Hum Genet 103:295-303.
-
(1998)
Hum Genet
, vol.103
, pp. 295-303
-
-
Hu, Q.1
Kukull, W.A.2
Bressler, S.L.3
Gray, M.D.4
Cam, J.A.5
Larson, E.B.6
Martin, G.M.7
Deeb, S.S.8
-
14
-
-
0034693448
-
A FE65 polymorphism associated with risk of developing sporadic late-onset Alzheimer's disease but not with Abeta loading in brains
-
Lambert JC, Mann D, Goumidi L, Harris J, Pasquier F, Frigard B, Cottel D, Lendon C, Iwatsubo T, Amouyel P, Chartier-Harlin MC. 2000. A FE65 polymorphism associated with risk of developing sporadic late-onset Alzheimer's disease but not with Abeta loading in brains. Neurosci Lett 293:29-32.
-
(2000)
Neurosci Lett
, vol.293
, pp. 29-32
-
-
Lambert, J.C.1
Mann, D.2
Goumidi, L.3
Harris, J.4
Pasquier, F.5
Frigard, B.6
Cottel, D.7
Lendon, C.8
Iwatsubo, T.9
Amouyel, P.10
Chartier-Harlin, M.C.11
-
15
-
-
0029087026
-
Candidate gene for the chromosome 1 familial Alzheimer's disease locus
-
Levy-Lahad E, Wasco W, Poorkaj P, Romano DM, Oshima J, Pettingell WH, Yu CE, Jondro PD, Schmidt SD, Wang K, Crowley AC, Fu Y-H, Guenette Sy, Galas D, Nemens E, Wijsman EM, Bird TD, Schellenberg GD, Tanzi RE. 1995a. Candidate gene for the chromosome 1 familial Alzheimer's disease locus. Science 269:973-977.
-
(1995)
Science
, vol.269
, pp. 973-977
-
-
Levy-Lahad, E.1
Wasco, W.2
Poorkaj, P.3
Romano, D.M.4
Oshima, J.5
Pettingell, W.H.6
Yu, C.E.7
Jondro, P.D.8
Schmidt, S.D.9
Wang, K.10
Crowley, A.C.11
Fu, Y.-H.12
Guenette, Sy.13
Galas, D.14
Nemens, E.15
Wijsman, E.M.16
Bird, T.D.17
Schellenberg, G.D.18
Tanzi, R.E.19
-
16
-
-
0029150716
-
A familial Alzheimer's disease locus on chromosome 1
-
Levy-Lahad E, Wijsman EM, Nemens E, Anderson L, Goddard KA, Weber JL, Bird TD, Schellenberg GD. 1995b. A familial Alzheimer's disease locus on chromosome 1. Science 269:970-973.
-
(1995)
Science
, vol.269
, pp. 970-973
-
-
Levy-Lahad, E.1
Wijsman, E.M.2
Nemens, E.3
Anderson, L.4
Goddard, K.A.5
Weber, J.L.6
Bird, T.D.7
Schellenberg, G.D.8
-
17
-
-
8144228132
-
Association of late onset Alzheimer's disease with genetic variation in multiple members of the GAPD gene family
-
Li Y, Nowotny P, Holmans P, Smemo S, Kauwe J, Hinrichs T, Tacey K, Doil L, van Luchene R, Garcia V, Rowland C, Schrodi S, Leong D, Gorgic G, Chan J, Cravchik A, Ross D, Lau K, Kwok S, Chang S.-Y., Catanese J, Sninsky J, White T, Hardy J, Powell J, Lovestone S, Thal L, Owen M, Williams J, Goate A, Grupe A. 2004. Association of late onset Alzheimer's disease with genetic variation in multiple members of the GAPD gene family. Proc Natl Acad Sci USA 101:15688-15693.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 15688-15693
-
-
Li, Y.1
Nowotny, P.2
Holmans, P.3
Smemo, S.4
Kauwe, J.5
Hinrichs, T.6
Tacey, K.7
Doil, L.8
Van Luchene, R.9
Garcia, V.10
Rowland, C.11
Schrodi, S.12
Leong, D.13
Gorgic, G.14
Chan, J.15
Cravchik, A.16
Ross, D.17
Lau, K.18
Kwok, S.19
Chang, S.-Y.20
Catanese, J.21
Sninsky, J.22
White, T.23
Hardy, J.24
Powell, J.25
Lovestone, S.26
Thal, L.27
Owen, M.28
Williams, J.29
Goate, A.30
Grupe, A.31
more..
-
18
-
-
0021271971
-
Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease
-
McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM. 1984. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 34:939-944.
-
(1984)
Neurology
, vol.34
, pp. 939-944
-
-
McKhann, G.1
Drachman, D.2
Folstein, M.3
Katzman, R.4
Price, D.5
Stadlan, E.M.6
-
19
-
-
0032231375
-
Detecting marker-disease association by testing for Hardy-Weinberg disequilibrium at a marker locus
-
Nielsen DM, Ehm MG, Weir BS. 1998. Detecting marker-disease association by testing for Hardy-Weinberg disequilibrium at a marker locus. Am J Hum Genet 63:1531-1540.
-
(1998)
Am J Hum Genet
, vol.63
, pp. 1531-1540
-
-
Nielsen, D.M.1
Ehm, M.G.2
Weir, B.S.3
-
20
-
-
0034837775
-
The amyloid precursor protein locus and very-late-onset Alzheimer disease
-
Olson JM, Goddard KA, Dudek DM. 2001. The amyloid precursor protein locus and very-late-onset Alzheimer disease. Am J Hum Genet 69:895-899.
-
(2001)
Am J Hum Genet
, vol.69
, pp. 895-899
-
-
Olson, J.M.1
Goddard, K.A.2
Dudek, D.M.3
-
21
-
-
0034321630
-
No association between an intronic biallelic polymorphism of the FE65 gene and Alzheimer's disease
-
Papassotiropoulos A, Bagli M, Becker K, Jessen F, Maier W, Rao ML, Ludwig M, Heun R. 2000. No association between an intronic biallelic polymorphism of the FE65 gene and Alzheimer's disease. Int J Mol Med 6:587-589.
-
(2000)
Int J Mol Med
, vol.6
, pp. 587-589
-
-
Papassotiropoulos, A.1
Bagli, M.2
Becker, K.3
Jessen, F.4
Maier, W.5
Rao, M.L.6
Ludwig, M.7
Heun, R.8
-
22
-
-
0034971263
-
Lack of replication of association findings in complex disease: An analysis of 15 polymorphisms in prior candidate genes for sporadic Alzheimer's disease
-
Prince JA, Feuk L, Sawyer SL, Gottfries J, Ricksten A, Nagga K, Bogdanovic N, Blennow K, Brookes AJ. 2001. Lack of replication of association findings in complex disease: an analysis of 15 polymorphisms in prior candidate genes for sporadic Alzheimer's disease. Eur J Hum Genet 9:437-444.
-
(2001)
Eur J Hum Genet
, vol.9
, pp. 437-444
-
-
Prince, J.A.1
Feuk, L.2
Sawyer, S.L.3
Gottfries, J.4
Ricksten, A.5
Nagga, K.6
Bogdanovic, N.7
Blennow, K.8
Brookes, A.J.9
-
23
-
-
0034118493
-
Inference of population structure using multilocus genotype data
-
Pritchard JK, Stephens M, Donnelly P. 2000. Inference of population structure using multilocus genotype data. Genetics 155:945-959.
-
(2000)
Genetics
, vol.155
, pp. 945-959
-
-
Pritchard, J.K.1
Stephens, M.2
Donnelly, P.3
-
24
-
-
0029101491
-
Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene
-
Rogaev EI, Sherrington R, Rogaeva EA, Levesque G, Ikeda M, Liang Y, Chi H, Lin C, Holman K, Tsuda T, Mar L, Sorbi S, Nacmias B. Piacentini S, Amaducci L, Chumakov I, Cohen D, Lennfelt L, Fraser PE, Rommens JM, St. George-Hyslop PH. 1995. Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene. Nature 376:775-778.
-
(1995)
Nature
, vol.376
, pp. 775-778
-
-
Rogaev, E.I.1
Sherrington, R.2
Rogaeva, E.A.3
Levesque, G.4
Ikeda, M.5
Liang, Y.6
Chi, H.7
Lin, C.8
Holman, K.9
Tsuda, T.10
Mar, L.11
Sorbi, S.12
Nacmias, B.13
Piacentini, S.14
Amaducci, L.15
Chumakov, I.16
Cohen, D.17
Lennfelt, L.18
Fraser, P.E.19
Rommens, J.M.20
St. George-Hyslop, P.H.21
more..
-
25
-
-
0032461761
-
Apolipoprotein E and Alzheimer's disease. The tip of the susceptibility iceberg
-
Roses AD. 1998. Apolipoprotein E and Alzheimer's disease. The tip of the susceptibility iceberg. Ann NY Acad Sci 855:738-743.
-
(1998)
Ann NY Acad Sci
, vol.855
, pp. 738-743
-
-
Roses, A.D.1
-
26
-
-
0036155283
-
Score tests for association between traits and haplotypes when linkage phase is ambiguous
-
Schaid DJ, Rowland CM, Tines DE, Jacobson RM, Poland GA. 2002. Score tests for association between traits and haplotypes when linkage phase is ambiguous. Am J Hum Genet 70:425-434.
-
(2002)
Am J Hum Genet
, vol.70
, pp. 425-434
-
-
Schaid, D.J.1
Rowland, C.M.2
Tines, D.E.3
Jacobson, R.M.4
Poland, G.A.5
-
27
-
-
0029004341
-
Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease
-
Sherrington R, Rogaev EI, Liang Y, Rogaeva EA, Levesque G, Ikeda M, Chi H, Lin C, Li G, Holman K, Tsuda T, Mar L, Foncin J-F, Bruni AC, Montesi MP, Sorbi S, Rainero I, Pinessi L, Nee L, Chumakov I, Pollen D, Brookes A, Sanseau P, Polinsky RJ, Wasco W, Da Silva HAR, Haines JL, Pericak-Vance MA, Tanzi RE, Roses AD, Fraser PE, Rommens JM, St. George-Hyslop PH. 1995. Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease. Nature 375:754-760.
-
(1995)
Nature
, vol.375
, pp. 754-760
-
-
Sherrington, R.1
Rogaev, E.I.2
Liang, Y.3
Rogaeva, E.A.4
Levesque, G.5
Ikeda, M.6
Chi, H.7
Lin, C.8
Li, G.9
Holman, K.10
Tsuda, T.11
Mar, L.12
Foncin, J.-F.13
Bruni, A.C.14
Montesi, M.P.15
Sorbi, S.16
Rainero, I.17
Pinessi, L.18
Nee, L.19
Chumakov, I.20
Pollen, D.21
Brookes, A.22
Sanseau, P.23
Polinsky, R.J.24
Wasco, W.25
Da Silva, H.A.R.26
Haines, J.L.27
Pericak-Vance, M.A.28
Tanzi, R.E.29
Roses, A.D.30
Fraser, P.E.31
Rommens, J.M.32
St. George-Hyslop, P.H.33
more..
-
28
-
-
0027407565
-
Apolipoprotein E: High-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease
-
Strittmatter WJ, Saunders AM, Schmechel D, Pericak-Vance M, Enghild J, Salvesen GS, Roses AD. 1993. Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease. Proc Natl Acad Sci USA 90:1977-1981.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 1977-1981
-
-
Strittmatter, W.J.1
Saunders, A.M.2
Schmechel, D.3
Pericak-Vance, M.4
Enghild, J.5
Salvesen, G.S.6
Roses, A.D.7
-
29
-
-
0033538502
-
Genetic variability at the amyloid-beta precursor protein locus may contribute to the risk of late-onset Alzheimer's disease
-
Wavrant-De Vrieze F, Crook R, Holmans P, Kehoe P, Owen MJ, Williams J, Roehl K, Laliiri DK, Shears S, Booth J, Wu W, Goate A, Chartier-Harlin MC, Hardy J, Perez-Tur J. 1999. Genetic variability at the amyloid-beta precursor protein locus may contribute to the risk of late-onset Alzheimer's disease. Neurosci Lett 269:67-70.
-
(1999)
Neurosci Lett
, vol.269
, pp. 67-70
-
-
Wavrant-De Vrieze, F.1
Crook, R.2
Holmans, P.3
Kehoe, P.4
Owen, M.J.5
Williams, J.6
Roehl, K.7
Laliiri, D.K.8
Shears, S.9
Booth, J.10
Wu, W.11
Goate, A.12
Chartier-Harlin, M.C.13
Hardy, J.14
Perez-Tur, J.15
|