Differential inhibition by the Rho kinase inhibitor Y-27632 of the increases in contractility and Ca2+ transients induced by endothelin-1 in rabbit ventricular myocytes

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 371, Issue 3, 2005, Pages 185-194

  Chu, Li ^a,b   Norota, Ikuo ^a   Endoh, Masao ^a  

^a YAMAGATA UNIVERSITY   (Japan)

^b HEBEI MEDICAL UNIVERSITY   (China)

Author keywords

Ca2+ transients; Cardiac contractility; Endothelin 1; Rabbit ventricular myocardium; Rho kinase inhibition; Y 27632

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; BETA ADRENERGIC RECEPTOR; CALCIUM ION; ENDOTHELIN 1; INDO 1; ISOPRENALINE; RHO KINASE; RHO KINASE INHIBITOR;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVATION; HEART MUSCLE CELL; HEART MUSCLE CONTRACTILITY; HEART VENTRICLE; MYOFILAMENT; NONHUMAN; PROTEIN FUNCTION; RABBIT; REGULATORY MECHANISM; STATISTICAL SIGNIFICANCE;

ADRENERGIC BETA-AGONISTS; AMIDES; ANIMALS; CALCIUM; CELL SIZE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIN-1; ENZYME INHIBITORS; FLUORESCENT DYES; INDOLES; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; ISOPROTERENOL; MALE; MYOCARDIAL CONTRACTION; MYOCYTES, CARDIAC; PAPILLARY MUSCLES; PROTEIN-SERINE-THREONINE KINASES; PYRIDINES; RABBITS;

EID: 20044395280     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00210-005-1032-z     Document Type: Article

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