-
1
-
-
0036869408
-
Therapy of type 2 diabetes mellitus based on the actions of glucagon-like peptide-1
-
Holst JJ (2002) Therapy of type 2 diabetes mellitus based on the actions of glucagon-like peptide-1. Diabetes/Metab Res Rev 18:430-441
-
(2002)
Diabetes/Metab Res Rev
, vol.18
, pp. 430-441
-
-
Holst, J.J.1
-
2
-
-
0033028297
-
Is glucagon-like peptide 1 an incretin hormone?
-
Nauck M (1999) Is glucagon-like peptide 1 an incretin hormone? Diabetologia 42:373-379
-
(1999)
Diabetologia
, vol.42
, pp. 373-379
-
-
Nauck, M.1
-
3
-
-
0035106978
-
Mini review: The glucagon-like peptides
-
Drucker DJ (2001) Mini review: the glucagon-like peptides. Endocrinology 142:521-527
-
(2001)
Endocrinology
, vol.142
, pp. 521-527
-
-
Drucker, D.J.1
-
4
-
-
0024465989
-
Distribution and molecular forms of glucagon-like peptide in the dog
-
Suda K, Takahashi H, Fukase N, Manaka H, Tominaga M, Sasaki H (1989) Distribution and molecular forms of glucagon-like peptide in the dog. Life Sci 45:1793-1798
-
(1989)
Life Sci
, vol.45
, pp. 1793-1798
-
-
Suda, K.1
Takahashi, H.2
Fukase, N.3
Manaka, H.4
Tominaga, M.5
Sasaki, H.6
-
5
-
-
0028281773
-
Tissue and plasma concentrations of amidated and glycine-extended glucagon-like peptide 1 in humans
-
Orskov C, Rabenhoj L, Wettergren A, Kofod H, Holst JJ (1994) Tissue and plasma concentrations of amidated and glycine-extended glucagon-like peptide 1 in humans. Diabetes 43:535-539
-
(1994)
Diabetes
, vol.43
, pp. 535-539
-
-
Orskov, C.1
Rabenhoj, L.2
Wettergren, A.3
Kofod, H.4
Holst, J.J.5
-
6
-
-
0029797540
-
Glucagon-like peptide 1 undergoes differential tissue-specific metabolism in the anesthetized pig
-
Deacon CF, Pridal L, Klarskov L, Olesen M, Holst JJ (1996) Glucagon-like peptide 1 undergoes differential tissue-specific metabolism in the anesthetized pig. Am J Physiol, Endocrinol Metab 271:E458-E464
-
(1996)
Am J Physiol, Endocrinol Metab
, vol.271
-
-
Deacon, C.F.1
Pridal, L.2
Klarskov, L.3
Olesen, M.4
Holst, J.J.5
-
7
-
-
0029118049
-
Degradation of glucose-dependent insulinotropic polypeptide and truncated glucagon-like peptide-1 in vitro and in vivo by dipeptidyl peptidase-IV
-
Kieffer TJ, Mcintosh CHS, Pederson RA (1995) Degradation of glucose-dependent insulinotropic polypeptide and truncated glucagon-like peptide-1 in vitro and in vivo by dipeptidyl peptidase-IV. Endocrinology 136:3585-3596
-
(1995)
Endocrinology
, vol.136
, pp. 3585-3596
-
-
Kieffer, T.J.1
Mcintosh, C.H.S.2
Pederson, R.A.3
-
8
-
-
0036158954
-
Biological actions and therapeutic potential of the glucagon-like peptides
-
Drucker DJ (2002) Biological actions and therapeutic potential of the glucagon-like peptides. Gastroenterology 122:531-544
-
(2002)
Gastroenterology
, vol.122
, pp. 531-544
-
-
Drucker, D.J.1
-
9
-
-
0033175006
-
Glucagon-like peptide 1 (GLP-1): An intestinal hormone, signalling nutritional abundance, with an unusual therapeutic potential
-
Holst JJ (1999) Glucagon-like peptide 1 (GLP-1): an intestinal hormone, signalling nutritional abundance, with an unusual therapeutic potential. Trends Endocrinol Metab 10:229-235
-
(1999)
Trends Endocrinol Metab
, vol.10
, pp. 229-235
-
-
Holst, J.J.1
-
10
-
-
0033303516
-
Glucagon-like peptide-1-(7-36)amide is transformed to glucagon-like peptide-1-(9-36)amide by dipeptidyl peptidase iv in the capillaries supplying the L cells of the porcine intestine
-
Hansen L, Deacon CF, Orskov C, Holst JJ (1999) Glucagon-like peptide-1-(7-36)amide is transformed to glucagon-like peptide-1-(9-36)amide by dipeptidyl peptidase iv in the capillaries supplying the L cells of the porcine intestine. Endocrinology 140:5356-5363
-
(1999)
Endocrinology
, vol.140
, pp. 5356-5363
-
-
Hansen, L.1
Deacon, C.F.2
Orskov, C.3
Holst, J.J.4
-
11
-
-
0030572882
-
The hepatic vagal nerve is receptive to incretin hormone glucagon-like peptide-1, but not to glucose-dependent insulinotropic polypeptide, in the portal vein
-
Nishizawa M, Nakabayashi H, Uchida K, Nakagawa A, Niijima A (1996) The hepatic vagal nerve is receptive to incretin hormone glucagon-like peptide-1, but not to glucose-dependent insulinotropic polypeptide, in the portal vein. J Auton Nerv Syst 61:149-154
-
(1996)
J Auton Nerv Syst
, vol.61
, pp. 149-154
-
-
Nishizawa, M.1
Nakabayashi, H.2
Uchida, K.3
Nakagawa, A.4
Niijima, A.5
-
12
-
-
0034639946
-
The hepatic vagal reception of intraportal GLP-1 is via receptor different from the pancreatic GLP-1 receptor
-
Nishizawa M, Nakabayashi H, Kawai K et al. (2000) The hepatic vagal reception of intraportal GLP-1 is via receptor different from the pancreatic GLP-1 receptor. J Auton Nerv Syst 80:14-21
-
(2000)
J Auton Nerv Syst
, vol.80
, pp. 14-21
-
-
Nishizawa, M.1
Nakabayashi, H.2
Kawai, K.3
-
13
-
-
0033696456
-
Portal GLP-1 administration in rats augments the insulin response to glucose via neuronal mechanisms
-
Balkan B, Li X (2000) Portal GLP-1 administration in rats augments the insulin response to glucose via neuronal mechanisms. Am J Physiol, Regul Integr Comp Physiol 279:R1449-R1454
-
(2000)
Am J Physiol, Regul Integr Comp Physiol
, vol.279
-
-
Balkan, B.1
Li, X.2
-
14
-
-
0035434115
-
Glucose competence of the hepatoportal vein sensor requires the presence of an activated glucagon-like peptide-1 receptor
-
Burcelin R, Da Costa A, Drucker D, Thorens B (2001) Glucose competence of the hepatoportal vein sensor requires the presence of an activated glucagon-like peptide-1 receptor. Diabetes 50:1720-1728
-
(2001)
Diabetes
, vol.50
, pp. 1720-1728
-
-
Burcelin, R.1
Da Costa, A.2
Drucker, D.3
Thorens, B.4
-
15
-
-
0037403938
-
Effect of intraportal glucagon-like peptide-1 on glucose metabolism in conscious dogs
-
Nishizawa M, Moore MC, Shiota M et al. (2003) Effect of intraportal glucagon-like peptide-1 on glucose metabolism in conscious dogs. Am J Physiol, Endocrinol Metab 284:E1027-E1036
-
(2003)
Am J Physiol, Endocrinol Metab
, vol.284
-
-
Nishizawa, M.1
Moore, M.C.2
Shiota, M.3
-
16
-
-
0033957338
-
Portal vein afferents are critical for the sympathoadrenal response to hypoglycemia
-
Hevener AL, Bergman RN, Donovan CM (2000) Portal vein afferents are critical for the sympathoadrenal response to hypoglycemia. Diabetes 49:8-12
-
(2000)
Diabetes
, vol.49
, pp. 8-12
-
-
Hevener, A.L.1
Bergman, R.N.2
Donovan, C.M.3
-
17
-
-
0026027379
-
Importance of hepatic glucoreceptors in sympathoadrenal response to hypoglycemia
-
Donovan CM, Halter JB, Bergman RN (1991) Importance of hepatic glucoreceptors in sympathoadrenal response to hypoglycemia. Diabetes 40:155-158
-
(1991)
Diabetes
, vol.40
, pp. 155-158
-
-
Donovan, C.M.1
Halter, J.B.2
Bergman, R.N.3
-
18
-
-
0028141351
-
The role of liver glucosensors in the integrated sympathetic response induced by deep hypoglycemia in dogs
-
Hamilton-Wessler M, Bergman RN, Halter JB, Watanabe RM, Donovan CM (1994) The role of liver glucosensors in the integrated sympathetic response induced by deep hypoglycemia in dogs. Diabetes 43:1052-1060
-
(1994)
Diabetes
, vol.43
, pp. 1052-1060
-
-
Hamilton-Wessler, M.1
Bergman, R.N.2
Halter, J.B.3
Watanabe, R.M.4
Donovan, C.M.5
-
19
-
-
0029829821
-
Vagal hepatopancreatic reflex effect evoked by intraportal appearance of tGLP-1
-
Nakabayashi H, Nishizawa M, Nakagawa A, Takeda R, Nijima A (1996) Vagal hepatopancreatic reflex effect evoked by intraportal appearance of tGLP-1. Am J Physiol, Endocrinol Metab 34:E808-E813
-
(1996)
Am J Physiol, Endocrinol Metab
, vol.34
-
-
Nakabayashi, H.1
Nishizawa, M.2
Nakagawa, A.3
Takeda, R.4
Nijima, A.5
-
20
-
-
0033815547
-
Portal glucose infusion in the mouse induces hypoglycemia: Evidence that the hepatoportal glucose sensor stimulates glucose utilization
-
Burcelin R, Dolci W, Thorens B (2000) Portal glucose infusion in the mouse induces hypoglycemia: evidence that the hepatoportal glucose sensor stimulates glucose utilization. Diabetes 49:1635-1642
-
(2000)
Diabetes
, vol.49
, pp. 1635-1642
-
-
Burcelin, R.1
Dolci, W.2
Thorens, B.3
-
21
-
-
3042823921
-
Insulin-independent effects of GLP-1 on canine liver glucose metabolism: Duration of infusion and involvement of hepatoportal region
-
Dardevet D, Moore MC, Neal D, DiCostanzo CA, Snead W, Cherrington AD (2004) Insulin-independent effects of GLP-1 on canine liver glucose metabolism: duration of infusion and involvement of hepatoportal region. Am J Physiol, Endocrinol Metab 287:E75-E81
-
(2004)
Am J Physiol, Endocrinol Metab
, vol.287
-
-
Dardevet, D.1
Moore, M.C.2
Neal, D.3
DiCostanzo, C.A.4
Snead, W.5
Cherrington, A.D.6
-
22
-
-
0029871377
-
Transendothelial insulin transport is not saturable in vivo. No evidence for a receptor-mediated process
-
Steil GM, Ader M, Moore DM, Rebrin K, Bergman RN (1996) Transendothelial insulin transport is not saturable in vivo. No evidence for a receptor-mediated process. J Clin Invest 97:1497-1503
-
(1996)
J Clin Invest
, vol.97
, pp. 1497-1503
-
-
Steil, G.M.1
Ader, M.2
Moore, D.M.3
Rebrin, K.4
Bergman, R.N.5
-
23
-
-
0034088142
-
Accurate measurement of endogenous insulin secretion does not require separate assessment of C-peptide kinetics
-
Watanabe RM, Bergman RN (2000) Accurate measurement of endogenous insulin secretion does not require separate assessment of C-peptide kinetics. Diabetes 49:373-382
-
(2000)
Diabetes
, vol.49
, pp. 373-382
-
-
Watanabe, R.M.1
Bergman, R.N.2
-
24
-
-
0030667056
-
Glucagon-like peptide 1 inhibition of gastric emptying outweighs its insulinotropic effects in healthy humans
-
Nauck MA, Niedereichholz U, Ettler R et al. (1997) Glucagon-like peptide 1 inhibition of gastric emptying outweighs its insulinotropic effects in healthy humans. Am J Physiol, Endocrinol Metab 273:E981-E988
-
(1997)
Am J Physiol, Endocrinol Metab
, vol.273
-
-
Nauck, M.A.1
Niedereichholz, U.2
Ettler, R.3
-
25
-
-
0031756220
-
Insulinotropic hormone glucagon-like peptide-1-(7-37) appears not to augment insulin-mediated glucose uptake in young men during euglycemia
-
Ryan AS, Egan JM, Habener JF, Elahi D (1998) Insulinotropic hormone glucagon-like peptide-1-(7-37) appears not to augment insulin-mediated glucose uptake in young men during euglycemia. J Clin Endocrinol Metab 83:2399-2404
-
(1998)
J Clin Endocrinol Metab
, vol.83
, pp. 2399-2404
-
-
Ryan, A.S.1
Egan, J.M.2
Habener, J.F.3
Elahi, D.4
-
26
-
-
0026596851
-
Antidiabetogenic effect of glucagon-like peptide-1 (7-36)amide in normal subjects and patients with diabetes mellitus
-
Gutniak M, Orskov C, Holst JJ, Ahren B, Efendic S (1992) Antidiabetogenic effect of glucagon-like peptide-1 (7-36)amide in normal subjects and patients with diabetes mellitus. N Engl J Med 326:1316-1322
-
(1992)
N Engl J Med
, vol.326
, pp. 1316-1322
-
-
Gutniak, M.1
Orskov, C.2
Holst, J.J.3
Ahren, B.4
Efendic, S.5
-
27
-
-
0035514550
-
Effect of glucagon-like peptide 1 on non-insulin-mediated glucose uptake in the elderly patient with diabetes
-
Meneilly GS, McIntosh CHS, Pederson RA et al. (2001) Effect of glucagon-like peptide 1 on non-insulin-mediated glucose uptake in the elderly patient with diabetes. Diabetes Care 24:1951-1956
-
(2001)
Diabetes Care
, vol.24
, pp. 1951-1956
-
-
Meneilly, G.S.1
McIntosh, C.H.S.2
Pederson, R.A.3
-
28
-
-
0030949882
-
Blood glucose lowering and glucagonostatic effects of glucagon-like peptide 1 in insulin-deprived diabetic dogs
-
Freyse EJ, Becher T, El Hag O, Knospe S, Goke B, Fischer U (1997) Blood glucose lowering and glucagonostatic effects of glucagon-like peptide 1 in insulin-deprived diabetic dogs. Diabetes 46:824-828
-
(1997)
Diabetes
, vol.46
, pp. 824-828
-
-
Freyse, E.J.1
Becher, T.2
El Hag, O.3
Knospe, S.4
Goke, B.5
Fischer, U.6
-
29
-
-
0032956247
-
Glucagon-like peptide 1 increases insulin sensitivity in depancreatized dogs
-
Sandhu H, Wiesenthal SR, MacDonald PE et al. (1999) Glucagon-like peptide 1 increases insulin sensitivity in depancreatized dogs. Diabetes 48:1045-1053
-
(1999)
Diabetes
, vol.48
, pp. 1045-1053
-
-
Sandhu, H.1
Wiesenthal, S.R.2
MacDonald, P.E.3
-
30
-
-
0001082811
-
Effects of glucagon-like peptide 1 (7-36 amide) on glucose kinetics during somatostatin-induced suppression of insulin secretion in healthy men
-
Shalev A, Ninnis R, Keller U (1998) Effects of glucagon-like peptide 1 (7-36 amide) on glucose kinetics during somatostatin-induced suppression of insulin secretion in healthy men. Horm Res 49:221-225
-
(1998)
Horm Res
, vol.49
, pp. 221-225
-
-
Shalev, A.1
Ninnis, R.2
Keller, U.3
-
31
-
-
0028296643
-
Glucagon-like peptide 1 enhances glucose tolerance both by stimulation of insulin release and by increasing insulin-independent glucose disposal
-
D'Alessio DA, Kahn SE, Leusner CR, Ensinck JW (1994) Glucagon-like peptide 1 enhances glucose tolerance both by stimulation of insulin release and by increasing insulin-independent glucose disposal. J Clin Invest 93:2263-2266
-
(1994)
J Clin Invest
, vol.93
, pp. 2263-2266
-
-
D'Alessio, D.A.1
Kahn, S.E.2
Leusner, C.R.3
Ensinck, J.W.4
-
32
-
-
0028889380
-
Enteral enhancement of glucose disposition by both insulin-dependent and insulin-independent processes. A physiological role of glucagon-like peptide 1
-
D'Alessio DA, Prigeon RL, Ensinck JW (1995) Enteral enhancement of glucose disposition by both insulin-dependent and insulin-independent processes. A physiological role of glucagon-like peptide 1. Diabetes 44:1433-1437
-
(1995)
Diabetes
, vol.44
, pp. 1433-1437
-
-
D'Alessio, D.A.1
Prigeon, R.L.2
Ensinck, J.W.3
-
33
-
-
0029745122
-
GLP-1 does not acutely affect insulin sensitivity in healthy man
-
Orskov L, Holst JJ, Moller J et al. (1996) GLP-1 does not acutely affect insulin sensitivity in healthy man. Diabetologia 39:1227-1232
-
(1996)
Diabetologia
, vol.39
, pp. 1227-1232
-
-
Orskov, L.1
Holst, J.J.2
Moller, J.3
-
34
-
-
0030010364
-
The effect of glucagon-like peptide 1 (GLP-1) on glucose elimination in healthy subjects depends on the pancreatic glucoregulatory hormones
-
Toft-Nielsen M, Madsbad S, Holst JJ (1996) The effect of glucagon-like peptide 1 (GLP-1) on glucose elimination in healthy subjects depends on the pancreatic glucoregulatory hormones. Diabetes 45:552-556
-
(1996)
Diabetes
, vol.45
, pp. 552-556
-
-
Toft-Nielsen, M.1
Madsbad, S.2
Holst, J.J.3
-
35
-
-
0030798846
-
Glucagon-like peptide-1 reduces hepatic glucose production indirectly through insulin and glucagon in humans
-
Larsson H, Holst JJ, Ahren B (1997) Glucagon-like peptide-1 reduces hepatic glucose production indirectly through insulin and glucagon in humans. Acta Physiol Scand 160:413-422
-
(1997)
Acta Physiol Scand
, vol.160
, pp. 413-422
-
-
Larsson, H.1
Holst, J.J.2
Ahren, B.3
-
36
-
-
0028156856
-
Effect of glucagon-like peptide-1 (proglucagon 78-107 amide) on hepatic glucose production in healthy man
-
Hvidberg A, Nielsen MT, Hilsted J, Orskov C, Holst JJ (1994) Effect of glucagon-like peptide-1 (proglucagon 78-107 amide) on hepatic glucose production in healthy man. Metabolism 43:104-108
-
(1994)
Metabolism
, vol.43
, pp. 104-108
-
-
Hvidberg, A.1
Nielsen, M.T.2
Hilsted, J.3
Orskov, C.4
Holst, J.J.5
-
37
-
-
0032901016
-
Glucagon-like peptide-1 has no insulin-like effects in insulin-dependent diabetic dogs maintained normoglycemic and normoinsulinemic
-
Freyse EJ, Knospe S, Becher T, El Hag O, Goke B, Fischer U (1999) Glucagon-like peptide-1 has no insulin-like effects in insulin-dependent diabetic dogs maintained normoglycemic and normoinsulinemic. Metabolism 48:134-137
-
(1999)
Metabolism
, vol.48
, pp. 134-137
-
-
Freyse, E.J.1
Knospe, S.2
Becher, T.3
El Hag, O.4
Goke, B.5
Fischer, U.6
-
38
-
-
0042804811
-
Enteral infusion of glucose at rates approximating EGP enhances glucose disposal but does not cause hypoglycemia
-
Zangeneh F, Basu R, Shah P, Arora P, Camilleri M, Rizza RA (2003) Enteral infusion of glucose at rates approximating EGP enhances glucose disposal but does not cause hypoglycemia. Am J Physiol, Endocrinol Metab 285:E280-E286
-
(2003)
Am J Physiol, Endocrinol Metab
, vol.285
-
-
Zangeneh, F.1
Basu, R.2
Shah, P.3
Arora, P.4
Camilleri, M.5
Rizza, R.A.6
-
39
-
-
0942287346
-
Unlike mice, dogs exhibit effective glucoregulation during low-dose portal and peripheral glucose infusion
-
Moore MC, Cardin S, Edgerton DS et al. (2004) Unlike mice, dogs exhibit effective glucoregulation during low-dose portal and peripheral glucose infusion. Am J Physiol, Endocrinol Metab 286:E226-E233
-
(2004)
Am J Physiol, Endocrinol Metab
, vol.286
-
-
Moore, M.C.1
Cardin, S.2
Edgerton, D.S.3
-
40
-
-
3242730474
-
Role of incretin hormones in the regulation of insulin secretion in diabetic and nondiabetic humans
-
Holst JJ, Gromada J (2004) Role of incretin hormones in the regulation of insulin secretion in diabetic and nondiabetic humans. Am J Physiol, Endocrinol Metab 287:E199-E206
-
(2004)
Am J Physiol, Endocrinol Metab
, vol.287
-
-
Holst, J.J.1
Gromada, J.2
-
41
-
-
0036959991
-
Effects of glucagon-like peptide 1 on counterregulatory hormone responses, cognitive functions, and insulin secretion during hyperinsulinemic, stepped hypoglycemic clamp experiments in healthy volunteers
-
Nauck MA, Heimesaat MM, Behle K et al. (2002) Effects of glucagon-like peptide 1 on counterregulatory hormone responses, cognitive functions, and insulin secretion during hyperinsulinemic, stepped hypoglycemic clamp experiments in healthy volunteers. J Clin Endocrinol Metab 87:1239-1246
-
(2002)
J Clin Endocrinol Metab
, vol.87
, pp. 1239-1246
-
-
Nauck, M.A.1
Heimesaat, M.M.2
Behle, K.3
-
42
-
-
0030913976
-
Hierarchy of physiological responses to hypoglycemia: Relevance to clinical hypoglycemia in type I (insulin-dependent) diabetes mellitus
-
Cryer PE (1997) Hierarchy of physiological responses to hypoglycemia: relevance to clinical hypoglycemia in type I (insulin-dependent) diabetes mellitus. Horm Metab Res 29:92-96
-
(1997)
Horm Metab Res
, vol.29
, pp. 92-96
-
-
Cryer, P.E.1
-
43
-
-
0035143063
-
Alpha- and beta cell responses to small changes in plasma glucose in the conscious dog
-
Flattem N, Igawa K, Shiota M, Emshwiller MG, Neal DW, Cherrington AD (2001) Alpha- and beta cell responses to small changes in plasma glucose in the conscious dog. Diabetes 50:367-375
-
(2001)
Diabetes
, vol.50
, pp. 367-375
-
-
Flattem, N.1
Igawa, K.2
Shiota, M.3
Emshwiller, M.G.4
Neal, D.W.5
Cherrington, A.D.6
|