Studies on the structure-activity relationship of 2′,6′- dimethyl-l-tyrosine (Dmt) derivatives: Bioactivity profile of H-Dmt-NH-CH 3

Bioorganic and Medicinal Chemistry Letters

Volumn 15, Issue 3, 2005, Pages 599-602

  Fujita, Yoshio ^a   Tsuda, Yuko ^a   Motoyama, Takashi ^a   Li, Tingyou ^a   Miyazaki, Anna ^a   Yokoi, Toshio ^a   Sasaki, Yusuke ^b   Ambo, Akihiro ^b   Niizuma, Hideko ^b   Jinsmaa, Yunden ^c   Bryant, Sharon D ^c   Lazarus, Lawrence H ^c   Okada, Yoshio ^a  

^a KOBE GAKUIN UNIVERSITY   (Japan)

^b TOHOKU PHARMACEUTICAL UNIVERSITY   (Japan)

^c NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

Opioid agonist; Dmt; Structure activity relationship

Indexed keywords

2',6' DIMETHYLTYROSINE DERIVATIVE; HYDROGEN; MORPHINE; MU OPIATE RECEPTOR AGONIST; NITROGEN; OPIATE PEPTIDE; TYROSINE DERIVATIVE; UNCLASSIFIED DRUG;

ANALGESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHEMICAL BOND; CONTROLLED STUDY; DRUG ACTIVITY; MOUSE; NONHUMAN; RECEPTOR AFFINITY; STRUCTURE ACTIVITY RELATION;

ANALGESICS; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; GUINEA PIGS; ILIUM; LIGANDS; MALE; MICE; PAIN; RADIOLIGAND ASSAY; RECEPTORS, OPIOID, DELTA; RECEPTORS, OPIOID, MU; STRUCTURE-ACTIVITY RELATIONSHIP; TYROSINE; VAS DEFERENS;

EID: 19944431922     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2004.11.040     Document Type: Article

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