EGF-induced proliferation of adult human pancreatic duct cells is mediated by the MEK/ERK cascade

Laboratory Investigation

Volumn 85, Issue 1, 2005, Pages 65-74

  Rescan, Claude ^a   Le Bras, Stéphanie ^a   Lefebvre, Véronique H ^a   Frandsen, Ulrik ^a   Klein, Tino ^a   Foschi, Marco ^b   Pipeleers, Daniel G ^a   Scharfmann, Raphael ^a   Madsen, Ole D ^a   Heimberg, Harry ^a,c  

^a JDRF Center for Beta Cell Therapy   (Russian Federation)

^b UNIVERSITY OF FLORENCE   (Italy)

^c FREE UNIVERSITY OF BRUSSELS   (Belgium)

Author keywords

Duct cells; EGF; Human pancreas; MAP kinase; Proliferation

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; BETACELLULIN; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR 2; EPIDERMAL GROWTH FACTOR RECEPTOR 3; EPIDERMAL GROWTH FACTOR RECEPTOR 4; INSULIN; KI 67 ANTIGEN; LIGAND; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE KINASE 2; TYROSINE;

ADENOVIRUS; ADOLESCENT; ADULT; ARTICLE; CELL MOTILITY; CELL PROLIFERATION; CELL STRUCTURE; CHILD; CONTROLLED STUDY; HUMAN; HUMAN CELL; IN VITRO STUDY; INSULIN DEPENDENT DIABETES MELLITUS; NUCLEOTIDE SEQUENCE; PANCREAS DUCT; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION;

ADOLESCENT; ADULT; CELL PROLIFERATION; CELLS, CULTURED; CHILD; EPIDERMAL GROWTH FACTOR; FLAVONOIDS; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MAP KINASE KINASE 1; MAP KINASE KINASE KINASES; MAP KINASE SIGNALING SYSTEM; MIDDLE AGED; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; PANCREATIC DUCTS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 19944431623     PISSN: 00236837     EISSN: None     Source Type: Journal    
DOI: 10.1038/labinvest.3700204     Document Type: Article

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