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Volumn 6, Issue 6, 2005, Pages 421-430

Clinical features of molecular pathology of solid tumours in childhood

Author keywords

[No Author keywords available]

Indexed keywords

CHIMERIC PROTEIN; CYTOTOXIC AGENT; HYBRID PROTEIN; MOLECULAR MARKER; MYC PROTEIN; MYCN PROTEIN; NEUROTROPIN RECEPTOR 3; PROTEIN P53; RECEPTOR PROTEIN; RETINOBLASTOMA PROTEIN; RNA BINDING PROTEIN EWS; TRANSCRIPTION FACTOR ER81; TRANSCRIPTION FACTOR FKHR; TRANSCRIPTION FACTOR PAX3; TRANSCRIPTION FACTOR PAX7; UNCLASSIFIED DRUG; WT1 PROTEIN;

EID: 19944400145     PISSN: 14702045     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1470-2045(05)70209-6     Document Type: Review
Times cited : (11)

References (77)
  • 1
    • 0015043748 scopus 로고
    • Mutation and cancer: Statistical study of retinoblastoma
    • AG Knudson Jr Mutation and cancer: Statistical study of retinoblastoma Proc Natl Acad Sci USA 681971 20-823
    • (1971) Proc. Natl. Acad. Sci. USA , vol.68 , pp. 820-823
    • Knudson Jr., A.G.1
  • 2
    • 0028587166 scopus 로고
    • The genetics of Wilms' tumor-A case of disrupted development
    • ND Hastie The genetics of Wilms' tumor-A case of disrupted development Annu Rev Genet 1994 28 523-58
    • (1994) Annu. Rev. Genet. , vol.28 , pp. 523-558
    • Hastie, N.D.1
  • 3
    • 0037222381 scopus 로고    scopus 로고
    • Germline TP53 mutations and Li-Fraumeni syndrome
    • JM Varley Germline TP53 mutations and Li-Fraumeni syndrome Hum Mutat 21 2003 313-320
    • (2003) Hum. Mutat. , vol.21 , pp. 313-320
    • Varley, J.M.1
  • 4
    • 0030724929 scopus 로고    scopus 로고
    • Mutation analysis of p53 gene in childhood malignant solid tumors
    • T Kusafuka M Fukuzawa T Oue et al. Mutation analysis of p53 gene in childhood malignant solid tumors J Pediatr Surg 32 1997 1175-1180
    • (1997) J. Pediatr. Surg. , vol.32 , pp. 1175-1180
    • Kusafuka, T.1    Fukuzawa, M.2    Oue, T.3
  • 5
    • 0025284063 scopus 로고
    • A comparative study of immunohistochemical staining for neuron-specific enolase, protein gene product 9·5 and S-100 protein in neuroblastoma, Ewing's sarcoma and other round cell tumours in children
    • RL Carter SZ al-Sams R.P. Corbett S Clinton A comparative study of immunohistochemical staining for neuron-specific enolase, protein gene product 9·5 and S-100 protein in neuroblastoma, Ewing's sarcoma and other round cell tumours in children Histopathology 16 1990 461-467.
    • (1990) Histopathology , vol.16 , pp. 461-467
    • Carter, R.L.1    al-Sams, S.Z.2    Corbett, R.P.3    Clinton, S.4
  • 6
    • 0035221594 scopus 로고    scopus 로고
    • Ewing sarcoma vs lymphoblastic lymphoma: A comparative immunohistochemical study
    • DR Lucas G Bentley ME Dan et al. Ewing sarcoma vs lymphoblastic lymphoma: A comparative immunohistochemical study Am J Clin Pathol 115 2001 11-67
    • (2001) Am. J. Clin. Pathol. , vol.115 , pp. 11-17
    • Lucas, D.R.1    Bentley, G.2    Dan, M.E.3
  • 8
    • 0034979512 scopus 로고    scopus 로고
    • A multiplex real-time pcr assay for the detection of gene fusions observed in solid tumors
    • M Peter E Gilbert O Delatre A multiplex real-time pcr assay for the detection of gene fusions observed in solid tumors Lab Invest 81 2001 905-912
    • (2001) Lab. Invest. , vol.81 , pp. 905-912
    • Peter, M.1    Gilbert, E.2    Delattre, O.3
  • 9
    • 3843075248 scopus 로고    scopus 로고
    • Genomic approaches to hematologic malignancies
    • BL Ebert TR Golub Genomic approaches to hematologic malignancies Blood 104 2004 923-932.
    • (2004) Blood , vol.104 , pp. 923-932
    • Ebert, B.L.1    Golub, T.R.2
  • 10
    • 0034954414 scopus 로고    scopus 로고
    • Classification and diagnostic prediction of cancers using gene expression profiling and artificial neural networks
    • J Khan JS Wei M Ringner et al. Classification and diagnostic prediction of cancers using gene expression profiling and artificial neural networks Nat Med 7 2001 673-679.
    • (2001) Nat. Med. , vol.7 , pp. 673-679
    • Khan, J.1    Wei, J.S.2    Ringner, M.3
  • 11
    • 4143150844 scopus 로고    scopus 로고
    • Gene expression signatures identify rhabdomyosarcoma subtypes and detect a novel t(2;2)(q35;p23) translocation fusing PAX3 to NCOA1
    • M, Wachtel M, Dettling Koscielniak E, et al. Gene expresssion signature identify rhabdomyosarcoma subtypes and detect a novel t(2;2)(q35;p23) translocation fusing PAX3 to NCOA1. Cancer Res 2004;64:5539-45
    • (2004) Cancer Res. , vol.64 , pp. 5539-5545
    • Wachtel, M.1    Dettling, M.2    Koscielniak, E.3
  • 12
    • 0037165140 scopus 로고    scopus 로고
    • Prediction of central nervous system embryonal tumour outcome based on gene expression
    • Pomeroy SL, Tamayo P, Gaasenbeek M, et al. Prediction of central nervous system embryonal tumour outcome based on gene expression. Nature 2002; 415: 436-42.
    • (2002) Nature , vol.415 , pp. 436-442
    • Pomeroy, S.L.1    Tamayo, P.2    Gaasenbeek, M.3
  • 13
    • 4944248113 scopus 로고    scopus 로고
    • Prediction of clinical outcome using gene expression profiling and artificial neural networks for patients with neuroblastoma
    • Wei JS, Greer BT, Westermann F, et al. Prediction of clinical outcome using gene expression profiling and artificial neural networks for patients with neuroblastoma. Cancer Res 2004; 64: 6883-91.
    • (2004) Cancer Res. , vol.64 , pp. 6883-6891
    • Wei, J.S.1    Greer, B.T.2    Westermann, F.3
  • 14
    • 3342939836 scopus 로고    scopus 로고
    • Prognostic classification of relapsing favorable histology Wilms tumor using cDNA microarray expression profiling and support vector machines
    • Williams RD, Hing SN, Greer BT, et al. Prognostic classification of relapsing favorable histology Wilms tumor using cDNA microarray expression profiling and support vector machines. Genes Chromosomes Cancer 2004; 41: 65-79.
    • (2004) Genes Chromosomes Cancer , vol.41 , pp. 65-79
    • Williams, R.D.1    Hing, S.N.2    Greer, B.T.3
  • 15
    • 9144245019 scopus 로고    scopus 로고
    • cDNA array-CGH profiling identifies genomic alterations specific to stage and MYCN-amplification in neuroblastoma
    • Chen QR, Bilke S, Wei JS, et al. cDNA array-CGH profiling identifies genomic alterations specific to stage and MYCNamplification in neuroblastoma. BMC Genomics 2004; 5: 70.
    • (2004) BMC Genomics , vol.5 , pp. 70
    • Chen, Q.R.1    Bilke, S.2    Wei, J.S.3
  • 16
    • 0033757970 scopus 로고    scopus 로고
    • Molecular detection of minimal residual disease is a strong predictive factor of relapse in childhood B-lineage acute lymphoblastic leukaemia with medium risk features: A case control study of the International BFM study group
    • Biondi A, Valsecchi MG, Seriu T, et al. Molecular detection of minimal residual disease is a strong predictive factor of relapse in childhood B-lineage acute lymphoblastic leukaemia with medium risk features: A case control study of the International BFM study group. Leukaemia 2000; 14: 1939-43.
    • (2000) Leukaemia , vol.14 , pp. 1939-1943
    • Biondi, A.1    Valsecchi, M.G.2    Seriu, T.3
  • 17
    • 0033554684 scopus 로고    scopus 로고
    • Treatment of high-risk neuroblastoma with intensive chemotherapy, radiotherapy, autologous bone marrow transplantation, and 13-cis-retinoic acid
    • Matthay KK, Villablanca JG, Seeger RC, et al. Treatment of highrisk neuroblastoma with intensive chemotherapy, radiotherapy, autologous bone marrow transplantation, and 13-cis-retinoic acid. N Engl J Med 1999; 341: 1165-73.
    • (1999) N. Engl. J. Med. , vol.341 , pp. 1165-1173
    • Matthay, K.K.1    Villablanca, J.G.2    Seeger, R.C.3
  • 18
    • 0041475779 scopus 로고    scopus 로고
    • Neuroblastoma: Biology and molecular and chromosomal pathology
    • Schwab M, Westermann F, Hero B, Berthold F. Neuroblastoma: Biology and molecular and chromosomal pathology. Lancet Oncol 2003; 4: 472-80.
    • (2003) Lancet Oncol. , vol.4 , pp. 472-480
    • Schwab, M.1    Westermann, F.2    Hero, B.3    Berthold, F.4
  • 19
    • 0035889955 scopus 로고    scopus 로고
    • Histopathology (International Neuroblastoma Pathology Classification) and MYCN status in patients with peripheral neuroblastic tumors: A report from the Children's Cancer Group
    • Goto S, Umehara S, Gerbing RB, et al. Histopathology (International Neuroblastoma Pathology Classification) and MYCN status in patients with peripheral neuroblastic tumors: A report from the Children's Cancer Group. Cancer 2001; 92: 2699-708.
    • (2001) Cancer , vol.92 , pp. 2699-2708
    • Goto, S.1    Umehara, S.2    Gerbing, R.B.3
  • 20
    • 0036207665 scopus 로고    scopus 로고
    • MYCN expression in human rhabdomyosarcoma cell lines and tumour samples
    • Toffolatti L, Frascella E, Ninfo V, et al. MYCN expression in human rhabdomyosarcoma cell lines and tumour samples. J Pathol 2002; 196: 450-58.
    • (2002) J. Pathol. , vol.196 , pp. 450-458
    • Toffolatti, L.1    Frascella, E.2    Ninfo, V.3
  • 21
    • 20044391414 scopus 로고    scopus 로고
    • Relationship between MYCN copy number and expression in rhabdomyosarcomas and correlation with adverse prognosis in the alveolar subtype
    • Williamson D, Lu YJ, Gordon T, et al. Relationship between MYCN copy number and expression in rhabdomyosarcomas and correlation with adverse prognosis in the alveolar subtype. J Clin Oncol 2005; 23: 880-88.
    • (2005) J. Clin. Oncol. , vol.23 , pp. 880-888
    • Williamson, D.1    Lu, Y.J.2    Gordon, T.3
  • 22
    • 0037366067 scopus 로고    scopus 로고
    • Neuroblastoma: Biological insights into a clinical enigma
    • Brodeur GM. Neuroblastoma: Biological insights into a clinical Nat Rev Cancer 2003; 3: 203-16.
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 203-216
    • Brodeur, G.M.1
  • 23
    • 0028283753 scopus 로고
    • Cytogenetic abnormalities of small round cell tumours
    • Bown NP, Reid MM, Malcolm AJ, et al. Cytogenetic abnormalities of small round cell tumours. Med Pediatr Oncol 1994; 23: 124-29
    • (1994) Med. Pediatr. Oncol. , vol.23 , pp. 124-129
    • Bown, N.P.1    Reid, M.M.2    Malcolm, A.J.3
  • 24
    • 0034066405 scopus 로고    scopus 로고
    • Caspase 8 is deleted or silenced preferentially in childhood neuroblastomas with amplification of MYCN
    • Teitz T, Wei T, Valentine MB, et al. Caspase 8 is deleted or silenced preferentially in childhood neuroblastomas with amplification of MYCN. Nat Med 2000; 6: 529-35.
    • (2000) Nat. Med. , vol.6 , pp. 529-535
    • Teitz, T.1    Wei, T.2    Valentine, M.B.3
  • 25
    • 0021261878 scopus 로고
    • Amplification of N-myc in untreated human neuroblastomas correlates with advanced disease stage
    • Brodeur GM, Seeger RC, Schwab M, et al. Amplification of N-myc in untreated human neuroblastomas correlates with advanced disease stage. Science 1984; 224: 1121-14.
    • (1984) Science , vol.224 , pp. 1121-1141
    • Brodeur, G.M.1    Seeger, R.C.2    Schwab, M.3
  • 26
    • 0034453338 scopus 로고    scopus 로고
    • Natural history and biology of stage A neuroblastoma: A Pediatric Oncology Group Study
    • Alvarado CS, London WB, Look AT, et al. Natural history and biology of stage A neuroblastoma: A Pediatric Oncology Group Study. J Pediatr Hematol Oncol 2000; 22: 197-205.
    • (2000) J. Pediatr. Hematol. Oncol. , vol.22 , pp. 197-205
    • Alvarado, C.S.1    London, W.B.2    Look, A.T.3
  • 27
    • 0031049728 scopus 로고    scopus 로고
    • N-Myc gene amplification is a major prognostic factor in localized neuroblastoma: Results of the French NBL 90 study
    • for the Neuroblastoma Study Group of the Societe Francaise d'Oncologie Pediatrique (SFOP)
    • Rubie H, Hartmann O, Michon J, et al, for the Neuroblastoma Study Group of the Societe Francaise d'Oncologie Pediatrique (SFOP). N-Myc gene amplification is a major prognostic factor in localized neuroblastoma: results of the French NBL 90 study. J Clin Oncol 1997; 15: 1171-82.
    • (1997) J. Clin. Oncol. , vol.15 , pp. 1171-1182
    • Rubie, H.1    Hartmann, O.2    Michon, J.3
  • 28
    • 0031418166 scopus 로고    scopus 로고
    • Loss of chromosome 1p may have a prognostic value in localised neuroblastoma: Results of the French NBL 90 Study
    • for the Neuroblastoma Study Group of the Societe Francaise d'Oncologie Pediatrique (SFOP)
    • Rubie H, Delattre O, Hartmann O, et al, for the Neuroblastoma Study Group of the Societe Francaise d'Oncologie Pediatrique (SFOP). Loss of chromosome 1p may have a prognostic value in localised neuroblastoma: results of the French NBL 90 Study. Eur J Cancer 1997; 33: 1917-22.
    • (1997) Eur. J. Cancer , vol.33 , pp. 1917-1922
    • Rubie, H.1    Delattre, O.2    Hartmann, O.3
  • 29
    • 13344275864 scopus 로고    scopus 로고
    • Allelic loss of chromosome 1p as a predictor of unfavorable outcome in patients with neuroblastoma
    • Caron H, van Sluis P, de Kraker J, et al. Allelic loss of chromosome 1p as a predictor of unfavorable outcome in patients with neuroblastoma. N Engl J Med 1996; 334: 225-30.
    • (1996) N. Engl. J. Med. , vol.334 , pp. 225-230
    • Caron, H.1    van Sluis, P.2    de Kraker, J.3
  • 30
    • 0033600283 scopus 로고    scopus 로고
    • Gain of chromosome arm 17q and adverse outcome in patients with neuroblastoma
    • Bown N, Cotterill S, Lastowska M, et al. Gain of chromosome arm 17q and adverse outcome in patients with neuroblastoma. N Engl J Med 1999; 340: 1954-61.
    • (1999) N. Engl. J. Med. , vol.340 , pp. 1954-1961
    • Bown, N.1    Cotterill, S.2    Lastowska, M.3
  • 31
    • 0035882058 scopus 로고    scopus 로고
    • Deconstructing myc
    • Eisenman RN. Deconstructing myc. Genes Dev 2001; 15: 2023-30.
    • (2001) Genes Dev. , vol.15 , pp. 2023-2030
    • Eisenman, R.N.1
  • 32
    • 0034327928 scopus 로고    scopus 로고
    • MYCN expression is not prognostic of adverse outcome in advanced-stage neuroblastoma with nonamplified MYCN
    • Cohn SL, London WB, Huang D, et al. MYCN expression is not prognostic of adverse outcome in advanced-stage neuroblastoma with nonamplified MYCN. J Clin Oncol 2000; 18: 3604-13
    • (2000) J. Clin. Oncol. , vol.18 , pp. 3604-3613
    • Cohn, S.L.1    London, W.B.2    Huang, D.3
  • 33
    • 0043073176 scopus 로고    scopus 로고
    • Identification of genes that are regulated transcriptionally by Myc in childhood tumors
    • Raetz EA, Kim MK, Moos P, et al. Identification of genes that are regulated transcriptionally by Myc in childhood tumors. Cancer 2003; 98: 841-53.
    • (2003) Cancer , vol.98 , pp. 841-853
    • Raetz, E.A.1    Kim, M.K.2    Moos, P.3
  • 34
    • 0037601662 scopus 로고    scopus 로고
    • Quality assessment of genetic markers used for therapy stratification
    • Ambros IM, Benard J, Boavida M, et al. Quality assessment of genetic markers used for therapy stratification. J Clin Oncol 2003; 21: 2077-84.
    • (2003) J. Clin. Oncol. , vol.21 , pp. 2077-2084
    • Ambros, I.M.1    Benard, J.2    Boavida, M.3
  • 35
    • 0036604377 scopus 로고    scopus 로고
    • Quantitation of GD2 synthase mRNA by real-time reverse transcription-polymerase chain reaction: Utility in bone marrow purging of neuroblastoma by anti-GD2 antibody 3F8
    • Cheung IY, Lo Piccolo MS, Collins N, et al. Quantitation of GD2 synthase mRNA by real-time reverse transcription-polymerase chain reaction: utility in bone marrow purging of neuroblastoma by anti-GD2 antibody 3F8. Cancer 2002; 94: 3042-48.
    • (2002) Cancer , vol.94 , pp. 3042-3048
    • Cheung, I.Y.1    Lo Piccolo, M.S.2    Collins, N.3
  • 36
    • 4544272181 scopus 로고    scopus 로고
    • Detection of residual neuroblastoma cells in bone marrow: Comparison of flow cytometry with immunocytochemistry
    • Swerts K, De Moerloose B, Dhooge C, et al. Detection of residual neuroblastoma cells in bone marrow: Comparison of flow cytometry with immunocytochemistry. Cytometry 2004; 61B: 9-19
    • (2004) Cytometry , vol.61 B , pp. 9-19
    • Swerts, K.1    De Moerloose, B.2    Dhooge, C.3
  • 37
    • 0035868665 scopus 로고    scopus 로고
    • Circulating neuroblastoma cells detected by reverse transcriptase polymerase chain reaction for tyrosine hydroxylase mRNA are an independent poor prognostic indicator in stage 4 neuroblastoma in children over 1 year
    • Burchill SA, Lewis IJ, Abrams KR, et al. Circulating neuroblastoma cells detected by reverse transcriptase polymerase chain reaction for tyrosine hydroxylase mRNA are an independent poor prognostic indicator in stage 4 neuroblastoma in children over 1 year. J Clin Oncol 2001; 19: 1795-801.
    • (2001) J. Clin. Oncol. , vol.19 , pp. 1795-1801
    • Burchill, S.A.1    Lewis, I.J.2    Abrams, K.R.3
  • 38
    • 0034671344 scopus 로고    scopus 로고
    • Quantitative tumor cell content of bone marrow and blood as a predictor of outcome in stage IV neuroblastoma: A Children's Cancer Group Study
    • Seeger RC, Reynolds CP, Gallego R,et al. Quantitative tumor cell content of bone marrow and blood as a predictor of outcome in stage IV neuroblastoma: A Children's Cancer Group Study. J Clin Oncol 2000; 18: 4067-76.
    • (2000) J. Clin. Oncol. , vol.18 , pp. 4067-4076
    • Seeger, R.C.1    Reynolds, C.P.2    Gallego, R.3
  • 39
    • 0037314747 scopus 로고    scopus 로고
    • Real-time analysis of tyrosine hydroxylase gene expression: A sensitive and semiquantitative marker for minimal residual disease detection of neuroblastoma
    • Lambooy LH, Gidding CE, van den Heuvel LP, et al. Real-time analysis of tyrosine hydroxylase gene expression: A sensitive and semiquantitative marker for minimal residual disease detection of neuroblastoma. Clin Cancer Res 2003; 9: 812-19.
    • (2003) Clin. Cancer Res. , vol.9 , pp. 812-819
    • Lambooy, L.H.1    Gidding, C.E.2    van den Heuvel, L.P.3
  • 40
    • 0026686674 scopus 로고
    • Gene fusion with an ETS DNA-binding domain caused by chromosome translocation in human tumours
    • Delattre O, Zucman J, Plougastel B, et al. Gene fusion with an ETS DNA-binding domain caused by chromosome translocation in human tumours. Nature 1992; 359: 162-65
    • (1992) Nature , vol.359 , pp. 162-165
    • Delattre, O.1    Zucman, J.2    Plougastel, B.3
  • 41
    • 0027179611 scopus 로고
    • Reverse transcriptase PCR amplification of EWS/FLI-1 fusion transcripts as a diagnostic test for peripheral primitive neuroectodermal tumors of childhood
    • Sorensen PH, Liu XF, Delattre O, et al. Reverse transcriptase PCR amplification of EWS/FLI-1 fusion transcripts as a diagnostic test for peripheral primitive neuroectodermal tumors of childhood. Diagn Mol Pathol 1993; 2: 147-57.
    • (1993) Diagn. Mol. Pathol. , vol.2 , pp. 147-157
    • Sorensen, P.H.1    Liu, X.F.2    Delattre, O.3
  • 42
    • 0027362619 scopus 로고
    • The Ewing's sarcoma EWS/FLI-1 fusion gene encodes a more potent transcriptional activator and is a more powerful transforming gene than FLI-1
    • May WA, Lessnick SL, Braun BS, et al. The Ewing's sarcoma EWS/FLI-1 fusion gene encodes a more potent transcriptional activator and is a more powerful transforming gene than FLI-1. Mol Cell Biol 1993; 13: 7393-98.
    • (1993) Mol. Cell Biol. , vol.13 , pp. 7393-7398
    • May, W.A.1    Lessnick, S.L.2    Braun, B.S.3
  • 43
    • 0027438827 scopus 로고
    • Combinatorial generation of variable fusion proteins in the Ewing family of tumours
    • Zucman J, Melot T, Desmaze C, et al. Combinatorial generation of variable fusion proteins in the Ewing family of tumours. EMBO J 1993; 12: 4481-87.
    • (1993) EMBO J. , vol.12 , pp. 4481-4487
    • Zucman, J.1    Melot, T.2    Desmaze, C.3
  • 44
    • 0028903089 scopus 로고
    • A variant Ewing's sarcoma translocation (7;22) fuses the EWS gene to the ETS gene ETV1
    • Jeon IS, Davis JN, Braun BS, et al. A variant Ewing's sarcoma translocation (7;22) fuses the EWS gene to the ETS gene ETV1. Oncogene 1995; 10: 1229-34.
    • (1995) Oncogene , vol.10 , pp. 1229-1234
    • Jeon, I.S.1    Davis, J.N.2    Braun, B.S.3
  • 45
    • 0043136766 scopus 로고    scopus 로고
    • FUS/ERG gene fusions in Ewing's tumors
    • Shing DC, McMullan DJ, Roberts P, et al. FUS/ERG gene fusions in Ewing's tumors. Cancer Res 2003; 63: 4568-76.
    • (2003) Cancer Res. , vol.63 , pp. 4568-4576
    • Shing, D.C.1    McMullan, D.J.2    Roberts, P.3
  • 46
    • 9244236526 scopus 로고    scopus 로고
    • Does expression of different EWS chimeric transcripts define clinically distinct risk groups of Ewing tumor patients?
    • Zoubek A, Dockhorn-Dworniczak B, Delattre O, et al. Does expression of different EWS chimeric transcripts define clinically distinct risk groups of Ewing tumor patients? J Clin Oncol 1996; 14: 1245-51.
    • (1996) J. Clin. Oncol. , vol.14 , pp. 1245-1251
    • Zoubek, A.1    Dockhorn-Dworniczak, B.2    Delattre, O.3
  • 47
    • 0033870294 scopus 로고    scopus 로고
    • Association of EWS-FLI1 type 1 fusion with lower proliferative rate in Ewing's sarcoma
    • de Alava E, Panizo A, Antonescu CR, et al. Association of EWSFLI1 type 1 fusion with lower proliferative rate in Ewing's sarcoma. Am J Pathol 2000; 156: 849-55.
    • (2000) Am. J. Pathol. , vol.156 , pp. 849-855
    • de Alava, E.1    Panizo, A.2    Antonescu, C.R.3
  • 48
    • 0033037075 scopus 로고    scopus 로고
    • EWS-FLI1 and EWS-ERG gene fusions are associated with similar clinical phenotypes in Ewing's sarcoma
    • Ginsberg JP, de Alava E, Ladanyi M, et al. EWS-FLI1 and EWSERG gene fusions are associated with similar clinical phenotypes in Ewing's sarcoma. J Clin Oncol 1999; 17: 1809-14.
    • (1999) J. Clin. Oncol. , vol.17 , pp. 1809-1814
    • Ginsberg, J.P.1    de Alava, E.2    Ladanyi, M.3
  • 49
    • 0033119006 scopus 로고    scopus 로고
    • Differential transactivation by alternative EWS-FLI1 fusion proteins correlates with clinical heterogeneity in Ewing's sarcoma
    • Lin PP, Brody RI, Hamelin AC, et al. Differential transactivation by alternative EWS-FLI1 fusion proteins correlates with clinical heterogeneity in Ewing's sarcoma. Cancer Res 1999; 59: 1428-32.
    • (1999) Cancer Res. , vol.59 , pp. 1428-1432
    • Lin, P.P.1    Brody, R.I.2    Hamelin, A.C.3
  • 50
    • 0012730932 scopus 로고    scopus 로고
    • Frequency and implications of chromosome 8 and 12 gains in Ewing sarcoma
    • Maurici D, Perez-Atayde A, Grier HE, et al. Frequency and implications of chromosome 8 and 12 gains in Ewing sarcoma. Cancer Genet Cytogenet 1998; 100: 106-10.
    • (1998) Cancer Genet. Cytogenet. , vol.100 , pp. 106-110
    • Maurici, D.1    Perez-Atayde, A.2    Grier, H.E.3
  • 51
    • 0034663196 scopus 로고    scopus 로고
    • Prognostic impact of P53 status in Ewing sarcoma
    • de Alava E, Antonescu CR, Panizo A, et al. Prognostic impact of P53 status in Ewing sarcoma. Cancer 2000; 89: 783-92.
    • (2000) Cancer , vol.89 , pp. 783-792
    • de Alava, E.1    Antonescu, C.R.2    Panizo, A.3
  • 52
    • 0034663338 scopus 로고    scopus 로고
    • Prognostic impact of INK4A deletion in Ewing sarcoma
    • Wei G, Antonescu CR, de Alava E, et al. Prognostic impact of INK4A deletion in Ewing sarcoma. Cancer 2000; 89: 793-99.
    • (2000) Cancer , vol.89 , pp. 793-799
    • Wei, G.1    Antonescu, C.R.2    de Alava, E.3
  • 53
    • 18344399058 scopus 로고    scopus 로고
    • Predictive potential of testing for bone marrow involvement in Ewing tumor patients by RT-PCR: A preliminary evaluation
    • Zoubek A, Ladenstein R, Windhager R, et al. Predictive potential of testing for bone marrow involvement in Ewing tumor patients by RT-PCR: A preliminary evaluation. Int J Cancer 1998; 79: 56-60.
    • (1998) Int. J. Cancer , vol.79 , pp. 56-60
    • Zoubek, A.1    Ladenstein, R.2    Windhager, R.3
  • 54
    • 18744411798 scopus 로고    scopus 로고
    • Increased risk of systemic relapses associated with bone marrow micrometastasis and circulating tumor cells in localized ewing tumor
    • Schleiermacher G, Peter M, Oberlin O, et al. Increased risk of systemic relapses associated with bone marrow micrometastasis and circulating tumor cells in localized ewing tumor. J Clin Oncol 2003; 21: 85-91.
    • (2003) J. Clin. Oncol. , vol.21 , pp. 85-91
    • Schleiermacher, G.1    Peter, M.2    Oberlin, O.3
  • 55
    • 10744233322 scopus 로고    scopus 로고
    • The predictive potential of molecular detection in the nonmetastatic Ewing family of tumors
    • Avigad S, Cohen IJ, Zilberstein J, et al. The predictive potential of molecular detection in the nonmetastatic Ewing family of tumors. Cancer 2004; 100: 1053-58.
    • (2004) Cancer , vol.100 , pp. 1053-1058
    • Avigad, S.1    Cohen, I.J.2    Zilberstein, J.3
  • 56
    • 0027521658 scopus 로고
    • Fusion of a fork head domain gene to PAX3 in the solid tumour alveolar rhabdomyosarcoma
    • Galili N, Davis RJ, Fredericks WJ, et al. Fusion of a fork head domain gene to PAX3 in the solid tumour alveolar rhabdomyosarcoma. Nat Genet 1993; 5: 230-35.
    • (1993) Nat. Genet. , vol.5 , pp. 230-235
    • Galili, N.1    Davis, R.J.2    Fredericks, W.J.3
  • 57
    • 0028364374 scopus 로고
    • Fusion of PAX7 to FKHR by the variant t(1;13)(p36;q14) translocation in alveolar rhabdomyosarcoma
    • Davis RJ, D'Cruz CM, Lovell MA, et al. Fusion of PAX7 to FKHR by the variant t(1;13)(p36;q14) translocation in alveolar rhabdomyosarcoma. Cancer Res 1994; 54: 2869-72.
    • (1994) Cancer Res. , vol.54 , pp. 2869-2872
    • Davis, R.J.1    D'Cruz, C.M.2    Lovell, M.A.3
  • 58
    • 0037102443 scopus 로고    scopus 로고
    • Genetic heterogeneity in the alveolar rhabdomyosarcoma subset without typical gene fusions
    • Barr FG, Qualman SJ, Macris MH, et al. Genetic heterogeneity in the alveolar rhabdomyosarcoma subset without typical gene fusions. Cancer Res 2002; 62: 4704-10
    • (2002) Cancer Res. , vol.62 , pp. 4704-4710
    • Barr, F.G.1    Qualman, S.J.2    Macris, M.H.3
  • 59
    • 0029162454 scopus 로고
    • The alveolar rhabdomyosarcoma PAX3/FKHR fusion protein is a transcriptional activator
    • Sublett JE, Jeon IS, Shapiro DN. The alveolar rhabdomyosarcoma PAX3/FKHR fusion protein is a transcriptional ctivator. Oncogene 1995; 11: 545-52.
    • (1995) Oncogene , vol.11 , pp. 545-552
    • Sublett, J.E.1    Jeon, I.S.2    Shapiro, D.N.3
  • 60
    • 0035860134 scopus 로고    scopus 로고
    • Detection of the PAX3-FKHR fusion gene in paediatric rhabdomyosarcoma: A reproducible predictor of outcome?
    • Anderson J, Gordon T, McManus A, et al. Detection of the PAX3- FKHR fusion gene in paediatric rhabdomyosarcoma: A reproducible predictor of outcome? Br J Cancer 2001; 85: 831-35.
    • (2001) Br. J. Cancer , vol.85 , pp. 831-835
    • Anderson, J.1    Gordon, T.2    McManus, A.3
  • 61
    • 0036605806 scopus 로고    scopus 로고
    • PAX3-FKHR and PAX7-FKHR gene fusions are prognostic indicators in alveolar rhabdomyosarcoma: A report from the children's oncology group
    • Sorensen PH, Lynch JC, Qualman SJ, et al. PAX3-FKHR and PAX7-FKHR gene fusions are prognostic indicators in alveolar rhabdomyosarcoma: A report from the children's oncology group. J Clin Oncol 2002; 20: 2672-79.
    • (2002) J. Clin. Oncol. , vol.20 , pp. 2672-2679
    • Sorensen, P.H.1    Lynch, J.C.2    Qualman, S.J.3
  • 62
    • 0029810867 scopus 로고    scopus 로고
    • Minimal disease detection in patients with alveolar rhabdomyosarcoma using a reverse transcriptase-polymerase chain reaction method
    • Kelly KM, Womer RB, Barr FG. Minimal disease detection in patients with alveolar rhabdomyosarcoma using a reverse transcriptase-polymerase chain reaction method. Cancer 1996; 78: 1320-27.
    • (1996) Cancer , vol.78 , pp. 1320-1327
    • Kelly, K.M.1    Womer, R.B.2    Barr, F.G.3
  • 63
    • 0035105525 scopus 로고    scopus 로고
    • Use of reverse transcriptase polymerase chain reaction for diagnosis and staging of alveolar rhabdomyosarcoma, Ewing sarcoma family of tumors, and desmoplastic small round cell tumor
    • Athale UH, Shurtleff SA, Jenkins JJ, et al. Use of reverse transcriptase polymerase chain reaction for diagnosis and staging of alveolar rhabdomyosarcoma, Ewing sarcoma family of tumors, and desmoplastic small round cell tumor. J Pediatr Hematol Oncol 2001; 23: 99-104.
    • (2001) J. Pediatr. Hematol. Oncol. , vol.23 , pp. 99-104
    • Athale, U.H.1    Shurtleff, S.A.2    Jenkins, J.J.3
  • 64
    • 0029928709 scopus 로고    scopus 로고
    • Synovial sarcoma: Prognostic significance of tumor size, margin of resection, and mitotic activity for survival
    • Singer S, Baldini EH, Demetri GD, et al. Synovial sarcoma: Prognostic significance of tumor size, margin of resection, and mitotic activity for survival. J Clin Oncol 1996; 14: 1201-08.
    • (1996) J. Clin. Oncol. , vol.14 , pp. 1201-1208
    • Singer, S.1    Baldini, E.H.2    Demetri, G.D.3
  • 65
    • 0029066330 scopus 로고
    • Fusion of SYT to two genes, SSX1 and SSX2, encoding proteins with homology to the Kruppel-associated box in human synovial sarcoma
    • Crew AJ, Clark J, Fisher C, et al. Fusion of SYT to two genes, SSX1 and SSX2, encoding proteins with homology to the Kruppelassociated box in human synovial sarcoma. EMBO J 1995; 14: 2333-40.
    • (1995) EMBO J. , vol.14 , pp. 2333-2340
    • Crew, A.J.1    Clark, J.2    Fisher, C.3
  • 66
    • 0032518634 scopus 로고    scopus 로고
    • SYT-SSX gene fusion as a determinant of morphology and prognosis in synovial sarcoma
    • Kawai A, Woodruff J, Healey JH, et al. SYT-SSX gene fusion as a determinant of morphology and prognosis in synovial sarcoma. N Engl J Med 1998; 338: 153-60.
    • (1998) N. Engl. J. Med. , vol.338 , pp. 153-160
    • Kawai, A.1    Woodruff, J.2    Healey, J.H.3
  • 67
    • 0036144655 scopus 로고    scopus 로고
    • Impact of SYT-SSX fusion type on the clinical behavior of synovial sarcoma: A multi-institutional retrospective study of 243 patients
    • Ladanyi M, Antonescu CR, Leung DH, et al. Impact of SYT-SSX fusion type on the clinical behavior of synovial sarcoma: A multiinstitutional retrospective study of 243 patients. Cancer Res 2002; 62: 135-40.
    • (2002) Cancer Res. , vol.62 , pp. 135-140
    • Ladanyi, M.1    Antonescu, C.R.2    Leung, D.H.3
  • 68
    • 0034938146 scopus 로고    scopus 로고
    • Clinical impact of molecular and cytogenetic findings in synovial sarcoma
    • Panagopoulos I, Mertens F, Isaksson M, et al. Clinical impact of molecular and cytogenetic findings in synovial sarcoma. Genes Chromosomes Cancer 2001; 31: 362-72.
    • (2001) Genes Chromosomes Cancer , vol.31 , pp. 362-372
    • Panagopoulos, I.1    Mertens, F.2    Isaksson, M.3
  • 69
    • 0033168038 scopus 로고    scopus 로고
    • The SYT-SSX1 variant of synovial sarcoma is associated with a high rate of tumor cell proliferation and poor clinical outcome
    • Nilsson G, Skytting B, Xie Y, et al. The SYT-SSX1 variant of synovial sarcoma is associated with a high rate of tumor cell proliferation and poor clinical outcome. Cancer Res 1999; 59: 3180-84.
    • (1999) Cancer Res. , vol.59 , pp. 3180-3184
    • Nilsson, G.1    Skytting, B.2    Xie, Y.3
  • 70
    • 0030341370 scopus 로고    scopus 로고
    • Specificity of the EWS/WT1 gene fusion for desmoplastic small round cell tumour
    • Ladanyi M, Gerald WL. Specificity of the EWS/WT1 gene fusion for desmoplastic small round cell tumour. J Pathol 1996; 180: 462.
    • (1996) J. Pathol. , vol.180 , pp. 462
    • Ladanyi, M.1    Gerald, W.L.2
  • 71
    • 2642647094 scopus 로고    scopus 로고
    • Truncating mutations of hSNF5/INI1 in aggressive paediatric cancer
    • Versteege I, Sevenet N, Lange J, et al. Truncating mutations of hSNF5/ INI1 in aggressive paediatric cancer. Nature 1998; 394: 203-06.
    • (1998) Nature , vol.394 , pp. 203-206
    • Versteege, I.1    Sevenet, N.2    Lange, J.3
  • 72
    • 0032940605 scopus 로고    scopus 로고
    • Germ-line and acquired mutations of INI1 in atypical teratoid and rhabdoid tumors
    • Biegel JA, Zhou JY, Rorke LB, et al. Germ-line and acquired mutations of INI1 in atypical teratoid and rhabdoid tumors. Cancer Res 1999; 59: 74-79.
    • (1999) Cancer Res. , vol.59 , pp. 74-79
    • Biegel, J.A.1    Zhou, J.Y.2    Rorke, L.B.3
  • 73
    • 0031953233 scopus 로고    scopus 로고
    • A novel ETV6-NTRK3 gene fusion in congenital fibrosarcoma
    • Knezevich SR, McFadden DE, Tao W, et al. A novel ETV6-NTRK3 gene fusion in congenital fibrosarcoma. Nat Genet 1998; 18: 184-87.
    • (1998) Nat. Genet. , vol.18 , pp. 184-187
    • Knezevich, S.R.1    McFadden, D.E.2    Tao, W.3
  • 74
    • 0031738824 scopus 로고    scopus 로고
    • Congenital mesoblastic nephroma t(12;15) is associated with ETV6-NTRK3 gene fusion: Cytogenetic and molecular relationship to congenital (infantile) fibrosarcoma
    • Rubin BP, Chen CJ, Morgan TW, et al. Congenital mesoblastic nephroma t(12;15) is associated with ETV6-NTRK3 gene fusion: Cytogenetic and molecular relationship to congenital (infantile) fibrosarcoma. Am J Pathol 1998; 153: 1451-8.
    • (1998) Am. J. Pathol. , vol.153 , pp. 1451-1458
    • Rubin, B.P.1    Chen, C.J.2    Morgan, T.W.3
  • 75
    • 0029838115 scopus 로고    scopus 로고
    • Clinicopathologic correlates of loss of heterozygosity in Wilm's tumor: A preliminary analysis
    • Grundy P, Telzerow P, Moksness J, Breslow NE. Clinicopathologic correlates of loss of heterozygosity in Wilm's tumor: A preliminary analysis. Med Pediatr Oncol 1996; 27: 429-33.
    • (1996) Med. Pediatr. Oncol. , vol.27 , pp. 429-433
    • Grundy, P.1    Telzerow, P.2    Moksness, J.3    Breslow, N.E.4
  • 76
    • 0031754683 scopus 로고    scopus 로고
    • Loss of heterozygosity on chromosome 16 in sporadic Wilms' tumour
    • Grundy RG, Pritchard J, Scambler P, Cowell JK. Loss of heterozygosity on chromosome 16 in sporadic Wilms' tumour. Br J Cancer 1998; 78: 1181-87.
    • (1998) Br. J. Cancer , vol.78 , pp. 1181-1187
    • Grundy, R.G.1    Pritchard, J.2    Scambler, P.3    Cowell, J.K.4
  • 77
    • 0031747351 scopus 로고    scopus 로고
    • Allele loss in Wilms tumors of chromosome arms 11q, 16q, and 22q correlate with clinicopathological parameters
    • Klamt B, Schulze M, Thate C, et al. Allele loss in Wilms tumors of chromosome arms 11q, 16q, and 22q correlate with clinicopathological parameters. Genes Chromosomes Cancer 1998; 22: 287-94.
    • (1998) Genes Chromosomes Cancer , vol.22 , pp. 287-294
    • Klamt, B.1    Schulze, M.2    Thate, C.3


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