Effects of 18-month of growth hormone (GH) replacement therapy in patients with Sheehan's syndrome

Growth Hormone and IGF Research

Volumn 15, Issue 3, 2005, Pages 231-237

  Tanriverdi, F ^a   Unluhizarci, K ^a   Kula, M ^a   Guven, M ^a   Bayram, F ^a   Kelestimur, F ^a  

^a ERCIYES UNIVERSITY MEDICAL FACULTY   (Turkey)

Author keywords

Body composition; Bone mineral density; GH deficiency; GH replacement therapy; IGF I; Lipid profile; Sheehan's syndrome

Indexed keywords

HIGH DENSITY LIPOPROTEIN CHOLESTEROL; HUMAN GROWTH HORMONE; LOW DENSITY LIPOPROTEIN CHOLESTEROL; SOMATOMEDIN C; TRIACYLGLYCEROL;

ADULT; ANTHROPOMETRIC PARAMETERS; ARTHRALGIA; ARTICLE; BLOOD PRESSURE MEASUREMENT; BLOOD PRESSURE MONITORING; BONE DENSITY; CHOLESTEROL BLOOD LEVEL; CLINICAL ARTICLE; CLINICAL TRIAL; DOSE RESPONSE; DRUG DOSE REGIMEN; FEMALE; GROWTH HORMONE DEFICIENCY; HORMONE SUBSTITUTION; HUMAN; HYPOPITUITARISM; LONG TERM CARE; MAINTENANCE DRUG DOSE; PRIORITY JOURNAL; WAIST CIRCUMFERENCE;

ADULT; BLOOD GLUCOSE; BLOOD PRESSURE; BONE DENSITY; FEMALE; HORMONE REPLACEMENT THERAPY; HUMAN GROWTH HORMONE; HUMANS; HYPOPITUITARISM; INSULIN-LIKE GROWTH FACTOR I; LIPIDS; MIDDLE AGED; RECOMBINANT PROTEINS; TREATMENT OUTCOME;

EID: 19944386936     PISSN: 10966374     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ghir.2005.03.005     Document Type: Article

References (43)

1. R.C. Cuneo F. Salomon G.A. McGauley P.H. Sonksen The growth hormone deficiency syndrome in adults Clin. Endocrinol. (Oxford) 37 1992 387-397
2. B.A. Bengtsson S. Eden L. Lonn et al. Treatment of adults with growth hormone (GH) deficiency with recombinant human GH J. Clin. Endocrinol. Metab. 76 1993 309-317
3. R.C. Cuneo S. Judd J.D. Wallace et al. The Australian multicenter trial of growth hormone (GH) treatment in GH-deficient adults J. Clin. Endocrinol. Metab. 83 1998 107-116
4. J.O. Jorgensen S.A. Pedersen L. Thuesen et al. Beneficial effects of growth hormone treatment in GH-deficient adults Lancet 1 1989 1221-1225
5. R.C. Cuneo F. Salomon G.F. Watts R. Hesp P.H. Sonksen Growth hormone treatment improves serum lipids and lipoproteins in adults with growth hormone deficiency Metabolism 42 1993 1519-1523
6. H. de Boer G.J. Blok H.J. Voerman M. Phillips J.A. Schouten Serum lipid levels in growth hormone-deficient men Metabolism 43 1994 199-203
7. T. Rosen S. Eden G. Larson L. Wilhelmsen B.A. Bengtsson Cardiovascular risk factors in adult patients with growth hormone deficiency Acta Endocrinol. (Copenhagen) 129 1993 195-200
8. H. de Boer G.J. Blok A. van Lingen G.J. Teule P. Lips E.A. van der Veen Consequences of childhood-onset growth hormone deficiency for adult bone mass J. Bone Miner. Res. 9 1994 1319-1326
9. M. Degerblad N. Elgindy K. Hall H.E. Sjoberg M. Thoren Potent effect of recombinant growth hormone on bone mineral density and body composition in adults with panhypopituitarism Acta Endocrinol. (Copenhagen) 126 1992 387-393
10. G. Johannsson T. Rosen I. Bosaeus L. Sjostrom B.A. Bengtsson Two years of growth hormone (GH) treatment increases bone mineral content and density in hypopituitary patients with adult-onset GH deficiency J. Clin. Endocrinol. Metab. 81 1996 2865-2873
11. T. Rosen L. Wilhelmsen K. Landin-Wilhelmsen G. Lappas B.A. Bengtsson Increased fracture frequency in adult patients with hypopituitarism and GH deficiency Eur. J. Endocrinol. 137 1997 240-245
12. S.A. Beshyah A. Henderson R. Niththyananthan et al. The effects of short and long-term growth hormone replacement therapy in hypopituitary adults on lipid metabolism and carbohydrate tolerance J. Clin. Endocrinol. Metab. 80 1995 356-363
13. G. Johannsson J. Oscarsson T. Rosen et al. Effects of 1 year of growth hormone therapy on serum lipoprotein levels in growth hormone-deficient adults. Influence of gender and Apo(a) and ApoE phenotypes Arterioscler. Thromb. Vasc. Biol. 15 1995 2142-2150
14. D.L. Russell-Jones A.J. Weissberger G.F. Watts The effects of growth hormone replacement on serum lipids, lipoproteins, apolipoproteins and cholesterol precursors in adult growth hormone deficiency Endocrinol. Metab. 1 Suppl. 1994
15. H.B. Baum B.M. Biller J.S. Finkelstein et al. Effects of physiologic growth hormone therapy on bone density and body composition in patients with adult-onset growth hormone deficiency. A randomized, placebo-controlled trial Ann. Intern. Med. 125 1996 883-890
16. D.J. O'Halloran A. Tsatsoulis R.W. Whitehouse S.J. Holmes J.E. Adams S.M. Shalet Increased bone density after recombinant human growth hormone (GH) therapy in adults with isolated GH deficiency J. Clin. Endocrinol. Metab. 76 1993 1344-1348
17. T. Rosen B.A. Bengtsson Premature mortality due to cardiovascular disease in hypopituitarism Lancet 336 1990 285-288
18. H.L. Sheehan Postpartum necrosis of the anterior pituitary J. Pathol. Bacteriol. 45 1937 189-214
19. F. Kelestimur Sheehan's syndrome Pituitary 6 2003 181-188
20. F. Kelestimur GH deficiency and the degree of hypopituitarism Clin. Endocrinol. (Oxford) 42 1995 443-444
21. Consensus guidelines for the diagnosis and treatment of adults with growth hormone deficiency: Summary statement of the Growth Hormone Research Society Workshop on Adult Growth Hormone Deficiency, J. Clin. Endocrinol. Metab. 83 (1998) 379-381
22. W.T. Friedewald R.I. Levy D.S. Fredrickson Estimation of the concentration of low density lipoprotein cholesterol in plasma without use of the preparative ultracentrifuge Clin. Chem. 18 1972 499-502
23. G.B. Forbes The abdomen: Hip ratio normative data and observations on selected patients Int. J. Obes. 14 1990 149-157
24. R. Abs B.A. Bengtsson E. Hernberg-Stahl et al. GH replacement in 1034 growth hormone deficient hypopituitary adults: Demographic and clinical characteristics, dosing and safety Clin. Endocrinol. (Oxford) 50 1999 703-713
25. B.A. Bengtsson H.P. Koppeschaar R. Abs et al. Growth hormone replacement therapy is not associated with any increase in mortality. KIMS study group J. Clin. Endocrinol. Metab. 84 1999 4291-4292
26. P. Burman A.G. Johansson A. Siegbahn B. Vessby F.A. Karlsson Growth hormone (GH)-deficient men are more responsive to GH replacement therapy than women J. Clin. Endocrinol. Metab. 82 1997 550-555
27. J. Verhelst R. Abs M. Vandeweghe et al. Two years of replacement therapy in adults with growth hormone deficiency Clin. Endocrinol. (Oxford) 47 1997 485-494
28. B.A. Bengtsson R. Abs H. Bennmarker et al. The effects of treatment and the individual responsiveness to growth hormone (GH) replacement therapy in 665 GH-deficient adults. KIMS Study Group and the KIMS International Board J. Clin. Endocrinol. Metab. 84 1999 3929-3935
29. W.M. Drake S.J. Howell J.P. Monson S.M. Shalet Optimizing GH therapy in adults and children Endocr. Rev. 22 2001 425-450
30. G. Johannsson T. Rosen B.A. Bengtsson Individualized dose titration of growth hormone (GH) during GH replacement in hypopituitary adults Clin. Endocrinol. (Oxford) 47 1997 571-581
31. R.D. Murray S.J. Howell C.A. Lissett S.M. Shalet Pre-treatment IGF-I level is the major determinant of GH dosage in adult GH deficiency Clin. Endocrinol. (Oxford) 52 2000 537-542
32. F.L. Conceicao S. Fisker N. Vahl T.K. Hansen J.O. Jorgensen J.S. Christiansen Growth hormone treatment in adults: Is there a true gender difference? Growth Horm. IGF. Res. 11 Suppl. A 2001 43-48
33. A.J. Weissberger K.K. Ho L. Lazarus Contrasting effects of oral and transdermal routes of estrogen replacement therapy on 24-hour growth hormone (GH) secretion, insulin-like growth factor I, and GH-binding protein in postmenopausal women J. Clin. Endocrinol. Metab. 72 1991 374-381
34. P. Maison S. Griffin M. Beglah-Nicoue N. Haddad B. Balkau P. Chanson Impact of growth hormone (GH) treatment on cardivascular risk factors in GH-deficient adults: A metaanalysis of blinded, randomized, placebo-controlled trials J. Clin. Endocrinol Metab. 89 2004 2192-2199
35. J. Gibney J.D. Wallace T.J. Spinks et al. The effects of 10 years of recombinant human growth hormone (GH) in adult GH-deficient patients J. Clin. Endocrinol. Metab. 84 1999 2596-2602
36. G. Johannsson T. Rosen G. Lindsredt Effect of 2 years of growth hormone therapy on body composition and cardiovascular risk factors in adults with growth hormone deficiency Endocrinol. Metab. 3 Suppl. A 1996 3-12
37. D. Florakis V. Hung G. Kaltsas et al. Sustained reduction in circulating cholesterol in adult hypopituitary patients given low dose titrated growth hormone replacement therapy: A two year study Clin. Endocrinol. (Oxford) 53 2000 453-459
38. R.D. Murray G.E. Wieringa C.A. Lissett K.H. Darzy L.E. Smethurst S.M. Shalet Low-dose GH replacement improves the adverse lipid profile associated with the adult GH deficiency syndrome Clin. Endocrinol. (Oxford) 56 2002 525-532
39. J.M. Bland D.G. Altman Regression towards the mean BMJ 308 1994 1499
40. B. Abrahamsen T.L. Nielsen J. Hangaard et al. Dose-, IGF-I- and sex-dependent changes in lipid profile and body composition during GH replacement therapy in adult onset GH deficiency Eur. J. Endocrinol. 150 2004 671-679
41. M.B. Davidson Effect of growth hormone on carbohydrate and lipid metabolism Endocr. Rev. 8 1987 115-131
42. T. Rosen T. Hansson H. Granhed J. Szucs B.A. Bengtsson Reduced bone mineral content in adult patients with growth hormone deficiency Acta Endocrinol. (Copenhagen) 129 1993 201-206
43. P. Davidson R. Milne D. Chase C. Cooper Growth hormone replacement in adults and bone mineral density: Systematic review and meta-analysis Clin. Endocrinol. (Oxford) 60 2004 92-98