Phosphoregulation of mixed-lineage kinase 1 activity by multiple phosphorylation in the activation loop

Biochemistry

Volumn 43, Issue 51, 2004, Pages 16348-16355

  Durkin, John T ^a   Holskin, Beverly P ^a   Kopec, Karla K ^a   Reed, Matt S ^b   Spais, Chrysanthe M ^a   Steffy, Brian M ^a   Gessner, George ^a   Angeles, Thelma S ^a   Pohl, Jan ^b   Ator, Mark A ^a   Meyer, Sheryl L ^a  

^a CEPHALON INC   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; DATA ACQUISITION; MASS SPECTROMETRY; NITROGEN; PROTEINS;

GEL MOBILITY; IMMUNOBLOT; MIXED-LINEAGE KINASE 1 (MLK1);

ENZYME KINETICS;

ALANINE; AMINO ACID; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE; PHOSPHOTRANSFERASE; RECOMBINANT ENZYME; SERINE; THREONINE;

AMINO ACID SEQUENCE; ARTICLE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMUNOBLOTTING; MASS SPECTROMETRY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MUTATION; NUCLEOTIDE SEQUENCE; PHOSPHORYLATION; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; REGULATORY MECHANISM;

AMINO ACID SEQUENCE; ANIMALS; CHO CELLS; CRICETINAE; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; KINETICS; MAP KINASE KINASE KINASES; MASS SPECTROMETRY; MOLECULAR SEQUENCE DATA; MUTATION; PHOSPHORYLATION; PROTEIN STRUCTURE, TERTIARY; PROTEIN-SERINE-THREONINE KINASES; THREONINE;

MAMMALIA;

EID: 19944372717     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi049866y     Document Type: Article

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