Glutaconyl-CoA is the main toxic agent in glutaryl-CoA dehydrogenase deficiency (glutaric aciduria type I)

Medical Hypotheses

Volumn 65, Issue 2, 2005, Pages 330-333

  Lehnert, Willy ^a   Sass, Jörn Oliver ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

3 HYDROXYISOBUTYRYL COENZYME A DEACYLASE; COENZYME A; CYSTEINE; ENZYME; GLUTACONYL COENZYME A; GLUTARYL COENZYME A DEHYDROGENASE; METHACRYLYL COENZYME A; THIOL GROUP; TOXIC SUBSTANCE; UNCLASSIFIED DRUG;

ARTICLE; BRAIN INJURY; CHEMICAL REACTION; DRUG DESIGN; ENZYME ACTIVITY; ENZYME DEFICIENCY; EXCITOTOXICITY; GLUTARYL COENZYME A DEHYDROGENASE DEFICIENCY; HUMAN; NERVE DEGENERATION; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; URINE LEVEL;

ACYL COENZYME A; AMINO ACID METABOLISM, INBORN ERRORS; ANIMALS; BRAIN; CYSTEINE; GLUTARYL-COA DEHYDROGENASE; GLUTATHIONE; HUMANS; MICE; MICE, KNOCKOUT; MODELS, CHEMICAL; MODELS, THEORETICAL; OXIDOREDUCTASES ACTING ON CH-CH GROUP DONORS;

EID: 19744373983     PISSN: 03069877     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mehy.2005.02.021     Document Type: Article

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