Direct injection of plasmid DNA into the skin induces dermatitis by activation of monocytes through toll-like receptor 9

Journal of Gene Medicine

Volumn 7, Issue 5, 2005, Pages 664-671

  Sawamura, D ^a   Abe, R ^a   Goto, M ^a   Akiyama, M ^a   Hemmi, H ^b   Akira, S ^b   Shimizu, H ^a  

^a HOKKAIDO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b OSAKA UNIVERSITY   (Japan)

Author keywords

Gene therapy; Keratinocyte; Naked DNA

Indexed keywords

INTERLEUKIN 6; NAKED DNA; PLASMID DNA; REACTIVE OXYGEN METABOLITE; TOLL LIKE RECEPTOR 9;

ANIMAL EXPERIMENT; ARTICLE; CELL ACTIVATION; CELL INFILTRATION; CELL MIGRATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DERMATITIS; DRUG CONTAMINATION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; KNOCKOUT MOUSE; MONOCYTE; MOUSE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RAT; SKIN INFLAMMATION;

ANIMALS; CELL MOVEMENT; DERMATITIS; DNA; DNA-BINDING PROTEINS; EAR DISEASES; ENDOTOXINS; HUMANS; INJECTIONS, SUBCUTANEOUS; INTERLEUKIN-6; MICE; MICE, KNOCKOUT; MONOCYTES; NEUTROPHILS; OLIGODEOXYRIBONUCLEOTIDES; PLASMIDS; RATS; RATS, MUTANT STRAINS; REACTIVE OXYGEN SPECIES; RECEPTORS, CELL SURFACE; SKIN; TOLL-LIKE RECEPTOR 9;

BACTERIA (MICROORGANISMS); VERTEBRATA;

EID: 19744368619     PISSN: 1099498X     EISSN: None     Source Type: Journal    
DOI: 10.1002/jgm.709     Document Type: Article

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