Inhibitory effects of cancer cell proliferation by novel histone deacetylase inhibitors involve p21/WAF1 induction and G2/M arrest

Biological and Pharmaceutical Bulletin

Volumn 28, Issue 5, 2005, Pages 849-853

  Maeda, Taishi ^a   Nagaoka, Yasuo ^a   Kawai, Yuki ^a   Takagaki, Nobumasa ^b   Yasuda, Chikako ^b   Yogosawa, Shingo ^b   Sowa, Yoshihiro ^b   Sakai, Toshiyuki ^b   Uesato, Shinichi ^a  

^a KANSAI UNIVERSITY   (Japan)

^b KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

Author keywords

Cell cycle arrest; G 2 m phase; Hct116 cell; Histone deacetylase inhibitor; Mg63 cell; P21 waf1

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 1; HISTONE DEACETYLASE; HISTONE DEACETYLASE INHIBITOR; N (HYDROXY) 6 [(PHENYLACETYL)AMINO] 2 NAPHTHAMIDE; N [4 (SULFANYLMETHYL)BENZYL] 2 NAPHTHAMIDE; PROTEIN P53; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL; CELL CYCLE G2 PHASE; CELL PROLIFERATION; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFECT; DRUG INHIBITION; DRUG STRUCTURE; DRUG SYNTHESIS; GENE ACTIVITY; HUMAN; HUMAN CELL; IC 50; OSTEOSARCOMA CELL; PROMOTER REGION; PROTEIN INDUCTION; STRUCTURE ACTIVITY RELATION;

CELL DIVISION; CELL LINE, TUMOR; CELL PROLIFERATION; ENZYME INHIBITORS; G2 PHASE; HISTONE DEACETYLASES; HUMANS;

EID: 19644392125     PISSN: 09186158     EISSN: None     Source Type: Journal    
DOI: 10.1248/bpb.28.849     Document Type: Article

References (18)

1. Hassig C. A., Schreiber S. L., Curr. Opin. Chem. Biol., 1, 300-308 (1997).
2. Kouzarides T., Cuir. Opin. Genet. Dev., 9, 40-48 (1999).
3. Strahl B. D., Allis C. D., Nature (London), 403, 41-45 (2000).
4. Wade P. A., Hum. Mol. Genet., 10, 693-698 (2001).
5. Cress W. D., Seto E., J. Cell. Physiol., 184, 1-16 (2000).
6. Marks P., Rifkind R. A., Richon V. M., Breslow R., Miller T., Kelly W. K., Nat. Rev. Cancer, 1, 194-202 (2001).
7. Sowa Y., Orita T., Minamikawa S., Nakano K., Mizuno T., Nomura H., Sakai T., Biochem. Biophys. Res. Commun., 241, 142-150 (1997).
8. Hirose T., Sowa Y., Takahashi S., Saito S., Yasuda C., Shindo N., Furuichi K., Sakai T., Oncogene, 22, 7762-7773 (2003).
9. Finnin M. S., Donigian J. R., Cohen A., Richon V. M., Rifkind R. A., Marks P. A., Breslow R., Pavletich N. P., Nature (London), 401, 188-193 (1999).
10. Uesato S., Kitagawa M., Nagaoka Y., Maeda T., Kuwajima H., Yamori T., Bioorg. Med. Chem. Lett., 12, 1347-1349 (2002).
11. Maeda T., Nagaoka Y., Kuwajima H., Seno C., Maruyama S., Kaurotaki M., Uesato S., Bioorg. Med. Chem., 12, 4351-4360 (2004).
12. Mori H., Sakamoto K., Tsurumi Y., Takase S., Hino M., WO 00/21979 (2000)
13. [Chem. Abstr., 132, 288796 (2000)].
14. Sherr C. J., Roberts J. M.,Genes Dev., 9, 1149-1163 (1995).
15. Dulic V., Stein G. H., Far D. F., Reed S. I., Mol. Cell. Biol., 18, 546-557 (1998).
16. Ando T., Kawabe T., Ohara H., Ducommun B., Itoh M., Okaraoto T., J. Biol. Chem., 276, 42971-42977 (2001).
17. El-Deiry W. S., Tokino T., Velculescu V. E., Levy D. B., Parsons R., Trent J. M., Lin D., Mercer W. E., Kinzler K. W., Vogelstein B., Cell, 75, 817-825 (1993).
18. Vogelstein B., Kinzler K. W., Cell, 70, 523-526 (1992).