Subunit-dependent block by isoflurane of wild-type and mutant α1S270H GABAA receptor currents in Xenopus oocytes

Neuroscience Letters

Volumn 382, Issue 3, 2005, Pages 332-337

  Hall, Adam C ^a   Stevens, Renna J N ^a   Betts, Brooke A ^a   Yeung, Wing Yee ^a   Kelley, Jill C ^b   Harrison, Neil L ^b  

^a SMITH COLLEGE   (United States)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

Anesthetic; Desensitization; GABA; Inhibition; Isoflurane; Open channel

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID A RECEPTOR BLOCKING AGENT; BICUCULLINE; HISTIDINE; ISOFLURANE; PICROTOXIN; RECEPTOR SUBUNIT; SERINE;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; BINDING SITE; COMPARATIVE STUDY; CONCENTRATION RESPONSE; CONTROLLED STUDY; MUTANT; MUTATION; NONHUMAN; OOCYTE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; RECEPTOR BLOCKING; STEADY STATE; WILD TYPE; XENOPUS;

ANESTHETICS, INHALATION; ANIMALS; BICUCULLINE; DOSE-RESPONSE RELATIONSHIP, DRUG; EXCITATORY POSTSYNAPTIC POTENTIALS; GABA ANTAGONISTS; ISOFLURANE; MEMBRANE POTENTIALS; MUTATION; OOCYTES; PATCH-CLAMP TECHNIQUES; PICROTOXIN; PROTEIN SUBUNITS; RECEPTORS, GABA-A; RECOMBINANT PROTEINS; SUBSTRATE SPECIFICITY; XENOPUS;

EID: 19544386309     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2005.03.029     Document Type: Article

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