Isoflurane slows inactivation kinetics of rat recombinant α1β2γ2L GABAA receptors: Enhancement of GABAergic transmission despite an open-channel block

Neuroscience Letters

Volumn 307, Issue 2, 2001, Pages 97-100

  Hapfelmeier, Gerhard ^a   Haseneder, Rainer ^a   Eder, Matthias ^b   Adelsberger, Helmuth ^c   Kochs, Eberhard ^a   Rammes, Gerhard ^b   Zieglgänsberger, Walter ^b  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^b MAX PLANCK INSTITUTE OF PSYCHIATRY   (Germany)

^c UNIVERSITY OF MUNICH   (Germany)

Author keywords

Aminobutyric acid (A) receptor; Anesthetics; Channel block; Computer simulations; Isoflurane; Patch clamp

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; ENFLURANE; HALOTHANE; ION CHANNEL; ISOFLURANE;

ARTICLE; COMPUTER SIMULATION; CONTROLLED STUDY; EVOKED RESPONSE; GABAERGIC TRANSMISSION; HUMAN; HUMAN CELL; INHIBITION KINETICS; INHIBITORY POSTSYNAPTIC POTENTIAL; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; RAT;

ANESTHETICS, INHALATION; BRAIN; CELLS, CULTURED; DRUG INTERACTIONS; GAMMA-AMINOBUTYRIC ACID; HUMANS; ION CHANNELS; ISOFLURANE; MEMBRANE POTENTIALS; MODELS, NEUROLOGICAL; NEURAL INHIBITION; NEURONS; PATCH-CLAMP TECHNIQUES; PHARMACOKINETICS; RECEPTORS, GABA-A; RECOMBINANT PROTEINS; SYNAPTIC TRANSMISSION;

EID: 0035854615     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(01)01950-4     Document Type: Article

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