Increased expression and activity of matrix metalloproteinases characterize embolic cardiac myxomas

American Journal of Pathology

Volumn 166, Issue 6, 2005, Pages 1619-1628

  Orlandi, Augusto ^a   Ciucci, Alessandro ^a   Ferlosio, Amedeo ^a   Pellegrino, Antonio ^a   Chiariello, Luigi ^a   Spagnoli, Luigi Giusto ^a  

^a UNIVERSITY OF ROME TOR VERGATA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

GELATINASE A; GELATINASE B; GLYCOSAMINOGLYCAN; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERSTITIAL COLLAGENASE; MATRIX METALLOPROTEINASE; STROMELYSIN; TISSUE INHIBITOR OF METALLOPROTEINASE 1;

ADULT; AGED; AORTA ANEURYSM; ARTICLE; CLINICAL ARTICLE; ENZYME ACTIVITY; ENZYME SYNTHESIS; EXTRACELLULAR MATRIX; FEMALE; GENETIC TRANSCRIPTION; HEART FAILURE; HEART LEFT ATRIUM; HEART MYXOMA; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; MALE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR EMBOLISM; WESTERN BLOTTING; ZYMOGRAPHY;

EID: 19544386157     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9440(10)62472-8     Document Type: Article

References (48)

1. Burke AP, Virmani R: Atlas of Tumor Pathology, fasc 16, ed 3. Washington, Armed Forced Institute of Pathology, 1996, pp 21-46
2. Reynen K: Cardiac myxomas. N Engl J Med 1995, 333:1610-1617
3. Burke AP, Virmani R: Cardiac myxoma. A clinicopathologic study. Am J Clin Pathol 1993, 100:671-680
4. Johansson L: Histogenesis of cardiac myxomas. An immunohistochemical study of 19 cases, including one with glandular structures, and review of the literature. Arch Pathol Lab Med 1989, 113:735-741
5. Ha JW, Kang WC, Chung N, Chang BC, Rim SJ, Kwon JW, Jang Y, Shim WH, Cho SY, Kim SS, Cho SH: Echocardiographic and morphologic characteristics of left atrial myxoma and their relation to systemic embolism. Am J Cardiol 1999, 83:1579-1582
6. Negishi M, Sakamoto H, Sakamaki T, Ishikawa O, Kanda T, Tamura J, Kurabayashi M, Nagai R: Disaccharide analysis of glycosaminoglycans synthesized by cardiac myxoma cells in tumor tissues and in cell culture. Life Sci 2003, 73:849-856
7. Kairemo KJ, Blomqvist CP, Miettinen M: Cardiac myxomas. N Engl J Med 1996, 334:1407-1408
8. Pinede L, Duhaut P, Loire R: Clinical presentation of left atrial myxoma. A series of 112 consecutive cases. Medicine (Baltimore) 2001, 80:159-172
9. Parissis JT, Mentzikof D, Georgopoulou M, Gikopoulos M, Kanapitsas A, Merkouris K, Kefalas C: Correlation of interleukin-6 gene expression to immunologic features in patients with cardiac myxomas. J Interferon Cytokine Res 1996, 16:589-593
10. Stetler-Stevenson WG: Dynamics of matrix turnover during pathologic remodeling of the extracellular matrix. Am J Pathol 1996, 148:1345-1350
11. Oh J, Takahashi R, Kondo S, Mizoguchi A, Adachi E, Sasahara RM, Nishimura S, Imamura Y, Kitayama H, Alexander DB, Ide C, Horan TP, Arakawa T, Yoshida H, Nishikawa S, Itoh Y, Seiki M, Itohara S, Takahashi C, Noda M: The membrane-anchored MMP inhibitor RECK is a key regulator of extracellular matrix integrity and angiogenesis. Cell 2001, 107:789-800
12. Linask KK: Regulation of heart morphology: current molecular and cellular perspectives on the coordinated emergence of cardiac form and function. Birth Defects Res Part C Embryo Today 2003, 69:14-24
13. Schenk S, Hintermann E, Bilban M, Koshikawa N, Hojilla C, Khokha R, Quaranta V: Binding to EGF receptor of a laminin-5 EGF-like fragment liberated during MMP-dependent mammary gland involution. J Cell Biol 2003, 161:197-209
14. Shiomi T, Okada Y: MT1-MMP and MMP-7 in invasion and metastasis of human cancers. Cancer Metastasis Rev 2003, 22:145-152
15. Singer CF, Kronsteiner N, Marton E, Kubista M, Cullen KJ, Hirtenlehner K, Seifert M, Kubista E: MMP-2 and MMP-9 expression in breast cancer-derived human fibroblasts is differentially regulated by stromal-epithelial interactions. Breast Cancer Res Treat 2002, 72:69-77
16. Dollery CM, McEwan JR, Henney AM: Matrix metalloproteinases and cardiovascular disease. Circ Res 1995, 77:863-868
17. Hernandez-Barrantes S, Bernardo M, Toth M, Fridman R: Regulation of membrane type-matrix metalloproteinases. Semin Cancer Biol 2002, 12:131-138
18. Spinale FG: Matrix metalloproteinases: regulation and dysregulation in the failing heart. Circ Res 2002, 90:520-530
19. Soini Y, Satta J, Maatta M, Autio-Harmainen H: Expression of MMP2, MMP9, MT1-MMP, TIMP1, and TIMP2 mRNA in valvular lesions of the heart. J Pathol 2001, 194:225-231
20. Rabkin E, Aikawa M, Stone JR, Fukumoto Y, Libby P, Schoen FJ: Activated interstitial myofibroblasts express catabolic enzymes and mediate matrix remodeling in myxomatous heart valves. Circulation 2001, 104:2525-2532
21. Spinale FG, Coker ML, Thomas CV, Walker JD, Mukherjee R, Hebbar L: Time-dependent changes in matrix metalloproteinase activity and expression during the progression of congestive heart failure: relation to ventricular and myocyte function. Circ Res 1998, 82:482-495
22. Laemmli UK: Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970, 227:680-685
23. Bradford MM: A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976, 72:248-254
24. Towbin H, Staehelin T, Gordon J: Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sci USA 1979, 76:4350-4354
25. Orlandi A, Francesconi A, Cocchia D, Corsini A, Spagnoli LG: Phenotypic heterogeneity influences apoptotic susceptibility to retinoic acid and cis-platinum of rat arterial smooth muscle cells in vitro: implications for the evolution of experimental intimal thickening. Arterioscler Thromb Vasc Biol 2001, 21:1118-1123
26. Nakamura H, Fujii Y, Inoki I, Sugimoto K, Tanzawa K, Matsuki H, Miura R, Yamaguchi Y, Okada Y: Brevican is degraded by matrix metalloproteinases and aggrecanase-1 (ADAMTS4) at different sites. J Biol Chem 2000, 275:38885-38890
27. Arner EC, Decicco CP, Cherney R, Tortorella MD: Cleavage of native cartilage aggrecan by neutrophil collagenase (MMP-8) is distinct from endogenous cleavage by aggrecanase. J Biol Chem 1997, 272:9294-9299
28. Oh LY, Larsen PH, Krekoski CA, Edwards DR, Donovan F, Werb Z, Yong VW: Matrix metalloproteinase-9/gelatinase B is required for process outgrowth by oligodendrocytes. J Neurosci 1999, 19:8464-8475
29. Reuben PM, Brogley MA, Sun Y, Cheung HS: Molecular mechanism of the induction of metalloproteinases 1 and 3 in human fibroblasts by basic calcium phosphate crystals. Role of calcium-dependent protein kinase C alpha. J Biol Chem 2002, 277:15190-15198
30. Wilson MJ, Sellers RG, Wiehr C, Melamud O, Pei D, Peehl DM: Expression of matrix metalloproteinase-2 and -9 and their inhibitors, tissue inhibitor of metalloproteinase-1 and -2, in primary cultures of human prostatic stromal and epithelial cells. J Cell Physiol 2002, 191:208-216
31. Tsuzaki M, Bynum D, Almekinders L, Yang X, Faber J, Banes AJ: ATP modulates load-inducible IL-1beta, COX 2, and MMP-3 gene expression in human tendon cells. J Cell Biochem 2003, 89:556-562
32. Stygar D, Wang H, Vladic YS, Ekman G, Eriksson H, Sahlin L: Increased level of matrix metalloproteinases 2 and 9 in the ripening process of the human cervix. Biol Reprod 2002, 67:889-894
33. Chung HW, Lee JY, Moon HS, Hur SE, Park MH, Wen Y, Polan ML: Matrix metalloproteinase-2, membranous type 1 matrix metalloproteinase, and tissue inhibitor of metalloproteinase-2 expression in ectopic and eutopic endometrium. Fertil Steril 2002, 78:787-795
34. Groft LL, Muzik H, Rewcastle NB, Johnston RN, Knauper V, Lafleur MA, Forsyth PA, Edwards DR: Differential expression and localization of TIMP-1 and TIMP-4 in human gliomas. Br J Cancer 2001, 85:55-63
35. Cox G, O'Byrne KJ: Matrix metalloproteinases and cancer. Anticancer Res 2001, 21:4207-4219
36. Vu TH, Werb Z: Matrix metalloproteinases: effectors of development and normal physiology. Genes Dev 2000, 14:2123-2133
37. Stamenkovic I: Extracellular matrix remodelling: the role of matrix metalloproteinases. J Pathol 2003, 200:448-464
38. Lam RM, Hawkins ET, Roszka J: Cardiac myxoma: histochemical and ultrastructural localization of glycosaminoglycans and proteoglycans. Ultrastruct Pathol 1984, 6:69-81
39. Hardingham TE, Fosang AJ: Proteoglycans: many forms and many functions. FASEB J 1992, 6:861-870
40. Brown LM, Fox HL, Hazen SA, LaNoue KF, Rannels SR, Lynch CJ: Role of the matrixin MMP-2 in multicellular organization of adipocytes cultured in basement membrane components. Am J Physiol 1997, 272:937-949
41. Strongin AY, Bannikov G, Marmer BL, Grant GA, Goldberg GI: Mechanism of cell-surface activation of 72 kDa type IV gelatinase. J Biol Chem 1995, 270:5331-5338
42. Sato H, Takino T, Okada Y, Cao J, Shinagawa A, Yamamoto E, Seiki M: A matrix metalloproteinase expressed on the surface of invasive tumor cells. Nature 1994, 370:61-65
43. Visse R, Nagase H: Matrix metalloproteinases and tissue inhibitors of metalloproteinases: structure, function and biochemistry. Circ Res 2003, 92:827-839
44. Galis ZS, Khatri JJ: Matrix metalloproteinases in vascular remodeling and atherogenesis: the good, the bad and the ugly. Circ Res 2002, 90:251-262
45. Burke AP, Jarvelainen H, Kolodgie FD, Goel A, Wight TN, Virmani R: Superficial pseudoaneurysms: clinicopathologic aspects and involvement of extracellular matrix proteoglycans. Mod Pathol 2004, 17:482-488
46. Asanuma K, Magid R, Johnson C, Nerem RM, Galis ZS: Uniaxial strain upregulates matrix-degrading enzymes produced by human vascular smooth muscle cells. Am J Physiol 2003, 284: H1778-H1784
47. Lee RT, Yamamoto C, Feng Y, Potter-Perigo S, Briggs WH, Landschulz KT, Turi TG, Thompson JF, Libby P, Wight TN: Mechanical strain induces specific changes in the synthesis and organization of proteoglycans by vascular smooth muscle cells. J Biol Chem 2001, 276:13847-13851
48. Morishige K, Shimokawa H, Matsumoto Y, Eto Y, Uwatoku T, Abe K, Sueishi K, Takeshita A: Overexpression of matrix metalloproteinase-9 promotes intravascular thrombus formation in porcine coronary arteries in vivo. Cardiovasc Res 2003, 57:572-585