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Volumn 388, Issue 1, 2005, Pages 57-63

Decreased lipid efflux and increased susceptibility to cholesterol-induced apoptosis in macrophages lacking phosphatidylcholine transfer protein

Author keywords

Apolipoprotein aI; Atherosclerosis; Cholesterol; Macrophage; Mice; Phosphatidylcholine transfer protein

Indexed keywords

CYTOTOXICITY; GENE ENCODING; LIPID EFFLUX; MACROPHAGES;

EID: 19544373594     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20041899     Document Type: Article
Times cited : (13)

References (42)
  • 1
    • 0020972414 scopus 로고
    • Lipoprotein metabolism in the macrophage: Implications for cholesterol deposition in atheroscierosis
    • Brown, M. S. and Goldstein, J. L. (1983) Lipoprotein metabolism in the macrophage: implications for cholesterol deposition in atheroscierosis. Annu. Rev. Biochem. 52, 223-261
    • (1983) Annu. Rev. Biochem. , vol.52 , pp. 223-261
    • Brown, M.S.1    Goldstein, J.L.2
  • 3
    • 0036790413 scopus 로고    scopus 로고
    • Consecuences of cellular cholesterol accumulation: Basic concepts and physiological implications
    • Tabas, I. (2002) Consecuences of cellular cholesterol accumulation: basic concepts and physiological implications. J. Clin. Invest. 110, 905-911
    • (2002) J. Clin. Invest. , vol.110 , pp. 905-911
    • Tabas, I.1
  • 4
    • 0038028612 scopus 로고    scopus 로고
    • HDL apolipoproteins aid ABCA1: Partners in the removal of excess cellular cholesterol
    • Oram, J. F. (2003) HDL apolipoproteins aid ABCA1: partners in the removal of excess cellular cholesterol. Arterioscler. Thromb Vase. Biol. 23, 720-727
    • (2003) Arterioscler. Thromb Vase. Biol. , vol.23 , pp. 720-727
    • Oram, J.F.1
  • 5
    • 3042798281 scopus 로고    scopus 로고
    • ATP-binding cassette transporters 51 and G4 mediate cellular cholesterol efflux to high-density lipoproteins
    • Wang, N., Lan, D., Chen, W., Matsuura, F. and Tall, A. R. (2004) ATP-binding cassette transporters 51 and G4 mediate cellular cholesterol efflux to high-density lipoproteins. Proc. Natl. Acad. Sci. U.S.A. 101, 9774-9779
    • (2004) Proc. Natl. Acad. Sci. U.S.A. , vol.101 , pp. 9774-9779
    • Wang, N.1    Lan, D.2    Chen, W.3    Matsuura, F.4    Tall, A.R.5
  • 6
    • 0037044747 scopus 로고    scopus 로고
    • ABCA1-mediated cholesterol efflux is defective in free cholesterol-loaded macrophages. Mechanism involves enhanced ABCA1 degradation in a process requiring full NPC1 activity
    • Feng, B. and Tabas, I. (2002) ABCA1-mediated cholesterol efflux is defective in free cholesterol-loaded macrophages. Mechanism involves enhanced ABCA1 degradation in a process requiring full NPC1 activity, J. Biol. Chem. 277, 43271-43280
    • (2002) J. Biol. Chem. , vol.277 , pp. 43271-43280
    • Feng, B.1    Tabas, I.2
  • 7
    • 4344652838 scopus 로고    scopus 로고
    • Apoptosis and plaque destabilization in atherosclerosis: The role of macrophage apoptosis induced by cholesterol
    • Tabas, I. (2004) Apoptosis and plaque destabilization in atherosclerosis: the role of macrophage apoptosis induced by cholesterol. Cell Death Differ. 11 (Suppl. 1), S12-S16
    • (2004) Cell Death Differ. , vol.11 , Issue.1 SUPPL.
    • Tabas, I.1
  • 8
    • 0025766081 scopus 로고
    • Phospholipid transfer proteins
    • Wirtz, K. W. A. (1991) Phospholipid transfer proteins. Annu. Rev. Biochem. 60, 73-99
    • (1991) Annu. Rev. Biochem. , vol.60 , pp. 73-99
    • Wirtz, K.W.A.1
  • 9
    • 0032901292 scopus 로고    scopus 로고
    • START a lipid-binding domain in StAR, HD-ZIP and signalling proteins
    • Ponting, C. P. and Aravind, L. (1999) START a lipid-binding domain in StAR, HD-ZIP and signalling proteins. Trends Biochem. Sci 24, 130-132
    • (1999) Trends Biochem. Sci , vol.24 , pp. 130-132
    • Ponting, C.P.1    Aravind, L.2
  • 11
    • 0037155224 scopus 로고    scopus 로고
    • Phosphatidylcholine transfer protein promotes apolipoprotein A-I-med ated lipid efflux in Chinese hamster ovary cells
    • Baez, J.M., Barbour, S. E. and Cohen, D. E. (2002) Phosphatidylcholine transfer protein promotes apolipoprotein A-I-med ated lipid efflux in Chinese hamster ovary cells. J. Biol. Chem. 277, 5198-6206
    • (2002) J. Biol. Chem. , vol.277 , pp. 5198-6206
    • Baez, J.M.1    Barbour, S.E.2    Cohen, D.E.3
  • 14
    • 0035834740 scopus 로고    scopus 로고
    • Free cholesterol loading of macrophages is associated with widespread mitochondrial dysfunction and activation of the mitachondrial apoptosis pathway
    • Yao, P. M. and Tabas, I. (2001) Free cholesterol loading of macrophages is associated with widespread mitochondrial dysfunction and activation of the mitachondrial apoptosis pathway J. Biol. Chem. 276, 42468-42476
    • (2001) J. Biol. Chem. , vol.276 , pp. 42468-42476
    • Yao, P.M.1    Tabas, I.2
  • 15
    • 0033602389 scopus 로고    scopus 로고
    • Macrophage-targeted CTP:phosphocholine cyticylyltransferase (1-314) transgenic mice
    • Tang, W., Walsh, A. and Tabas, I. (1999) Macrophage-targeted CTP:phosphocholine cyticylyltransferase (1-314) transgenic mice. Biochim. Biophys. Acta 1437, 301-316
    • (1999) Biochim. Biophys. Acta , vol.1437 , pp. 301-316
    • Tang, W.1    Walsh, A.2    Tabas, I.3
  • 16
    • 0022556074 scopus 로고
    • Sequential flotation ultracentrifugation
    • Schumaker, V. N. and Puppione, D. L (1986) Sequential flotation ultracentrifugation Methods Enzymol. 128, 155-170
    • (1986) Methods Enzymol. , vol.128 , pp. 155-170
    • Schumaker, V.N.1    Puppione, D.L.2
  • 17
    • 0005849853 scopus 로고
    • Degradation of cationized low density lipoprotein and regulation of cholesterol metabolism in homozygous familial hypercholesterolemia fibroblasts
    • Basu, S. K., Goldstein, J. L., Anderson, G. W. and Brown, M. S. (1976) Degradation of cationized low density lipoprotein and regulation of cholesterol metabolism in homozygous familial hypercholesterolemia fibroblasts. Proc. Natl. Acad. Sci. U.S.A. 73, 3178-3182
    • (1976) Proc. Natl. Acad. Sci. U.S.A. , vol.73 , pp. 3178-3182
    • Basu, S.K.1    Goldstein, J.L.2    Anderson, G.W.3    Brown, M.S.4
  • 18
    • 0029043888 scopus 로고
    • A novel assay for apoptosis. Flow cylometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled annexin V
    • Vermes, I., Haanen, C., Steffens-Nakken, H. and Reutelingsperger, C. (1995) A novel assay for apoptosis. Flow cylometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled annexin V. J. Immunol. Methods 184, 39-51
    • (1995) J. Immunol. Methods , vol.184 , pp. 39-51
    • Vermes, I.1    Haanen, C.2    Steffens-Nakken, H.3    Reutelingsperger, C.4
  • 19
    • 0028964742 scopus 로고
    • Cell toxicity induced by inhibition of acyl coenzyme A:cholesterol acyltransterase and accumulation of unesterified cholesterol
    • Warner, G. J., Stoudt, G., Bamberger, M., Johnson, W.J. and Rothblat, G. H. (1995) Cell toxicity induced by inhibition of acyl coenzyme A:cholesterol acyltransterase and accumulation of unesterified cholesterol. J. Biol. Chem. 270, 5772-5778
    • (1995) J. Biol. Chem. , vol.270 , pp. 5772-5778
    • Warner, G.J.1    Stoudt, G.2    Bamberger, M.3    Johnson, W.J.4    Rothblat, G.H.5
  • 20
    • 0032748021 scopus 로고    scopus 로고
    • Cloning, gene structure, tissue-specific expression and chromosomal localization of human phosphatidylcholine transfer protein
    • Cohen, D. E., Green, R. M., Wu, M. K. and Beier, D. R. (1999) Cloning, gene structure, tissue-specific expression and chromosomal localization of human phosphatidylcholine transfer protein. Biochim Biophys. Acta 1447, 265-270
    • (1999) Biochim Biophys. Acta , vol.1447 , pp. 265-270
    • Cohen, D.E.1    Green, R.M.2    Wu, M.K.3    Beier, D.R.4
  • 21
    • 0029887237 scopus 로고    scopus 로고
    • CDNA cloning and tissue specific expression of the phosphatidylcholine transfer protein gene
    • Geijtenbeek T. B. H., Smith, A. J., Borst, P. and Wirtz, K. W. A. (1996) cDNA cloning and tissue specific expression of the phosphatidylcholine transfer protein gene. Biochem. J. 316, 19-55
    • (1996) Biochem. J. , vol.316 , pp. 19-55
    • Geijtenbeek, T.B.H.1    Smith, A.J.2    Borst, P.3    Wirtz, K.W.A.4
  • 22
    • 0038193486 scopus 로고    scopus 로고
    • The lipidation by hepatocytes of human apolipoprotein A-I occurs by both ABCA1-dependent and - Ndependent pathways
    • Kiss, R. S., McManus, D. C., Franklin, V., Tan, W. L., McKenzie, A., Chimini, G. and Marcel, Y. L. (2003) The lipidation by hepatocytes of human apolipoprotein A-I occurs by both ABCA1-dependent and - ndependent pathways. J. Biol. Chem. 278, 10119-10127
    • (2003) J. Biol. Chem. , vol.278 , pp. 10119-10127
    • Kiss, R.S.1    McManus, D.C.2    Franklin, V.3    Tan, W.L.4    McKenzie, A.5    Chimini, G.6    Marcel, Y.L.7
  • 23
    • 0242384924 scopus 로고    scopus 로고
    • Effects of apolipoprotein A-I on ATP-binding cassette transpoler A1-mediated efflux of macrophage phospholipid and cholesterol: Formation of nascent high density lipoprotein particles
    • Liu, L., Bortnick, A. E. Nickel, M., Dhanasekaran, P., Subbaiah, P. V., Lund-Katz, S., Rothblat, G. H. and Phillips, M. C. (2003) Effects of apolipoprotein A-I on ATP-binding cassette transpoler A1-mediated efflux of macrophage phospholipid and cholesterol: formation of nascent high density lipoprotein particles. J. Biol. Chem 278, 42976-42984
    • (2003) J. Biol. Chem , vol.278 , pp. 42976-42984
    • Liu, L.1    Bortnick, A.E.2    Nickel, M.3    Dhanasekaran, P.4    Subbaiah, P.V.5    Lund-Katz, S.6    Rothblat, G.H.7    Phillips, M.C.8
  • 26
    • 0023664794 scopus 로고
    • Macrophage free cholesterol content regulates apolipoprotein e synthesis
    • Mazzone, T. Gump, H., Diller, P and Getz, G. S. (1987) Macrophage free cholesterol content regulates apolipoprotein E synthesis. J Biol. Chem. 262, 11657-11662
    • (1987) J Biol. Chem. , vol.262 , pp. 11657-11662
    • Mazzone, T.1    Gump, H.2    Diller, P.3    Getz, G.S.4
  • 27
    • 0033600877 scopus 로고    scopus 로고
    • Apolipoprotein A-I stimulates secretion of apolipoprotein e by foam cell macrophages
    • Rees, D., Sloane, T. Jessup, W., Dean, R. T. and Kritharides, L. (1999) Apolipoprotein A-I stimulates secretion of apolipoprotein E by foam cell macrophages. J. Biol. Chem. 274, 27925-27933
    • (1999) J. Biol. Chem. , vol.274 , pp. 27925-27933
    • Rees, D.1    Sloane, T.2    Jessup, W.3    Dean, R.T.4    Kritharides, L.5
  • 28
    • 0036790522 scopus 로고    scopus 로고
    • Regulation and mechanisms of macrophage cholesterol efflux
    • Tall, A. R., Costet, F. and Wang, N. (2002) Regulation and mechanisms of macrophage cholesterol efflux. J. Clin. Invest. 110, 899-904
    • (2002) J. Clin. Invest. , vol.110 , pp. 899-904
    • Tall, A.R.1    Costet, F.2    Wang, N.3
  • 29
    • 0030481717 scopus 로고    scopus 로고
    • Apolipoprotein-mediated cellular cholesterol and phospholipid efflux depend on a functional Golgi apparatus
    • Mendez A. J. and Uint, L. (1996) Apolipoprotein-mediated cellular cholesterol and phospholipid efflux depend on a functional Golgi apparatus. J. Lipid Res. 37, 2510-2524
    • (1996) J. Lipid Res. , vol.37 , pp. 2510-2524
    • Mendez, A.J.1    Uint, L.2
  • 31
    • 0038193488 scopus 로고    scopus 로고
    • Secretory vesicular transport from the Golgi is altered during ATP-binding cassette protein A1 (ABCAl)-mediated cholesterol efflux
    • Zha, X., Gauthier, A., Genest, J. and McPherson, R. (2003) Secretory vesicular transport from the Golgi is altered during ATP-binding cassette protein A1 (ABCAl)-mediated cholesterol efflux. J Biol. Chem 278, 10002-10005
    • (2003) J Biol. Chem , vol.278 , pp. 10002-10005
    • Zha, X.1    Gauthier, A.2    Genest, J.3    McPherson, R.4
  • 32
    • 0024591235 scopus 로고
    • Rapid redistribution of Golgi proteins into the ER in cells treated with brefeldin A: Evidence for membrane cycling from Golgi to ER
    • Lippincott-Schwartz, J., Yuan, L. C., Bonifacino, J. S. and Klausner, R. D. (1989) Rapid redistribution of Golgi proteins into the ER in cells treated with brefeldin A: evidence for membrane cycling from Golgi to ER. Cell (Cambridge. Mass.) 56, 801-813
    • (1989) Cell (Cambridge. Mass.) , vol.56 , pp. 801-813
    • Lippincott-Schwartz, J.1    Yuan, L.C.2    Bonifacino, J.S.3    Klausner, R.D.4
  • 34
    • 0023008846 scopus 로고
    • Novel blockade by brefeldin a of intracellular transport of secretory proteins in cultured rat hepatocytes
    • Misumi, Y., Miki, K., Takatsuki A., Tamura, G. and Ikehara, Y. (1985) Novel blockade by brefeldin A of intracellular transport of secretory proteins in cultured rat hepatocytes. J. Biol. Chem. 261, 11398-11403
    • (1985) J. Biol. Chem. , vol.261 , pp. 11398-11403
    • Misumi, Y.1    Miki, K.2    Takatsuki, A.3    Tamura, G.4    Ikehara, Y.5
  • 35
    • 0026508561 scopus 로고
    • Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages
    • Fadok, V. A., Voelker, D. R., Campbell, P. A., Cohen, J. J., Bratton, D. L. and Henson, P. M. (1992) Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages. J. Immunol. 148, 2207-2216
    • (1992) J. Immunol. , vol.148 , pp. 2207-2216
    • Fadok, V.A.1    Voelker, D.R.2    Campbell, P.A.3    Cohen, J.J.4    Bratton, D.L.5    Henson, P.M.6
  • 37
    • 0033576675 scopus 로고    scopus 로고
    • More than one way to die: Apoptosis, necrosis and reactive oxygen damage
    • Fiers, W., Beyaert, R. Declercq, W. and Vandenabeele, P. (1999) More than one way to die: apoptosis, necrosis and reactive oxygen damage. Oncogene 18, 7719-7730
    • (1999) Oncogene , vol.18 , pp. 7719-7730
    • Fiers, W.1    Beyaert, R.2    Declercq, W.3    Vandenabeele, P.4
  • 38
    • 4344578601 scopus 로고    scopus 로고
    • Enrichment of endoplasmic reticulum with cholesterol inhibits SERCA2b activity in parallel with increased order of membrane lipids. Implications for depletion of ER calcium stores and apoptosis in cholesterol-loaded macrophages
    • Li, Y., Ge, M., Ciani, L., Kuriakose, G., Westover, E., Dura, M., Covey, D., Freed, J. H., Maxfield, F. R., Lytton, J. et al. (2004) Enrichment of endoplasmic reticulum with cholesterol inhibits SERCA2b activity in parallel with increased order of membrane lipids. Implications for depletion of ER calcium stores and apoptosis in cholesterol-loaded macrophages. J. Biol. Chem. 279, 37030-37039
    • (2004) J. Biol. Chem. , vol.279 , pp. 37030-37039
    • Li, Y.1    Ge, M.2    Ciani, L.3    Kuriakose, G.4    Westover, E.5    Dura, M.6    Covey, D.7    Freed, J.H.8    Maxfield, F.R.9    Lytton, J.10
  • 40
    • 0034672703 scopus 로고    scopus 로고
    • Cholesterol and phospholipid metabolism in macrophages
    • Tabas, I. (2000) Cholesterol and phospholipid metabolism in macrophages. Biochim. Biophys. Acta 1529, 154-174
    • (2000) Biochim. Biophys. Acta , vol.1529 , pp. 154-174
    • Tabas, I.1
  • 41
    • 0344896671 scopus 로고    scopus 로고
    • Cytotoxic cellular cholesterol is selectively removed by apoA-l via ABCA1
    • Kellner-Weibel, G., Luke, S. J. and Rothblat, G. H. (2003) Cytotoxic cellular cholesterol is selectively removed by apoA-l via ABCA1. Atherosclerosis 171, 235-243
    • (2003) Atherosclerosis , vol.171 , pp. 235-243
    • Kellner-Weibel, G.1    Luke, S.J.2    Rothblat, G.H.3
  • 42
    • 0032870291 scopus 로고    scopus 로고
    • Cytotoxic cholesterol is generated by the hydrolysis of cytoplasmic cholesteryl ester and transported to the plasma membrane
    • Kellner-Weibel, G. Geng, Y. J. and Rothblat, G. H. (1999) Cytotoxic cholesterol is generated by the hydrolysis of cytoplasmic cholesteryl ester and transported to the plasma membrane. Atherosclerosis 146, 309-319
    • (1999) Atherosclerosis , vol.146 , pp. 309-319
    • Kellner-Weibel, G.1    Geng, Y.J.2    Rothblat, G.H.3


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