The -374A allele of the receptor for advanced glycation end products gene is associated with a decreased risk of ischemic heart disease in African-Brazilians with type 2 diabetes

Molecular Genetics and Metabolism

Volumn 85, Issue 2, 2005, Pages 149-156

  Dos Santos, Kátia Gonçalves ^a   Canani, Luís Henrique ^b   Gross, Jorge Luiz ^b   Tschiedel, Balduíno ^c   Pires Souto, Kátia Elisabete ^c   Roisenberg, Israel ^a  

^a FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^b HOSPITAL DE CLÍNICAS DE PORTO ALEGRE   (Brazil)

^c Grupo Hospitalar Conceicao   (Brazil)

Author keywords

Brazilians; Diabetic nephropathy; Diabetic retinopathy; Ischemic heart disease; Polymorphism; RAGE; Type 2 diabetes

Indexed keywords

ADULT; AFRICA; AGED; ALLELE; ARTICLE; BRAZIL; CLINICAL EXAMINATION; CONFIDENCE INTERVAL; CONTROLLED STUDY; DISEASE ASSOCIATION; EVALUATION; FEMALE; GENETIC ANALYSIS; GENETIC SUSCEPTIBILITY; GENETIC TRANSCRIPTION; GENETIC VARIABILITY; GENOTYPE; GLYCATION; HUMAN; ISCHEMIC HEART DISEASE; LABORATORY TEST; LOGISTIC REGRESSION ANALYSIS; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; PHYSICAL EXAMINATION; PRIORITY JOURNAL; PROMOTER REGION; QUESTIONNAIRE; RISK ASSESSMENT;

AFRICAN CONTINENTAL ANCESTRY GROUP; AGED; BRAZIL; CASE-CONTROL STUDIES; DIABETES MELLITUS, TYPE 2; DIABETIC NEPHROPATHIES; DIABETIC RETINOPATHY; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; HUMANS; LINKAGE (GENETICS); MALE; MIDDLE AGED; MYOCARDIAL ISCHEMIA; POLYMORPHISM, GENETIC; PROMOTER REGIONS (GENETICS); RECEPTORS, IMMUNOLOGIC; RISK;

EID: 19444387736     PISSN: 10967192     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ymgme.2005.02.010     Document Type: Article

References (29)

1. D.S. Fong, L. Aiello, T.W. Gardner, G.L. King, G. Blankenship, J.D. Cavallerano, F.L. Ferris 3rd, and R. Klein for the American diabetes association, retinopathy in diabetes Diabetes Care 27 Suppl. 1 2004 S84 S87
2. R.M. Bruno, and J.L. Gross Prognostic factors in Brazilian diabetic patients starting dialysis: a 3.6-year follow-up study J. Diabetes Complications 14 2000 266 271
3. B.E. Sobel Effects of glycemic control and other determinants on vascular disease in type 2 diabetes Am. J. Med. 113 2002 12 S22
4. G.F. Salles, K.V. Bloch, and C.R. Cardoso Mortality and predictors of mortality in a cohort of Brazilian type 2 diabetic patients Diabetes Care 27 2004 1299 1305
5. T.A. Chowdhury, P.H. Dyer, S. Kumar, A.H. Barnett, and S.C. Bain Genetic determinants of diabetic nephropathy Clin. Sci. 96 1999 221 230
6. B.R. Winkelmann, and J. Hager Genetic variation in coronary heart disease and myocardial infarction: methodological overview and clinical evidence Pharmacogenomics 1 2000 73 94
7. K.M. Warpeha, and U. Chakravarthy Molecular genetics of microvascular disease in diabetic retinopathy Eye 17 2003 305 311
8. R. Singh, A. Barden, T. Mori, and L. Beilin Advanced glycation end-products: a review Diabetologia 44 2001 129 146
9. H. Vlassara, and M.R. Palace Diabetes and advanced glycation endproducts J. Intern. Med. 251 2002 87 101
10. D.M. Stern, S.D. Yan, S.F. Yan, and A.M. Schmidt Receptor for advanced glycation endproducts (RAGE) and the complications of diabetes Ageing Res. Rev. 1 2002 1 15
11. B.I. Hudson, L.G. Bucciarelli, T. Wendt, T. Sakaguchi, E. Lalla, W. Qu, Y. Lu, L. Lee, D.M. Stern, Y. Naka, R. Ramasamy, S.D. Yan, S.F. Yan, V. D'Agati, and A.M. Schmidt Blockade of receptor for advanced glycation endproducts: a new target for therapeutic intervention in diabetic complications and inflammatory disorders Arch. Biochem. Biophys. 419 2003 80 88
12. K. Sugaya, T. Fukagawa, K. Matsumoto, K. Mita, E. Takahashi, A. Ando, H. Inoko, and T. Ikemura Three genes in the human MHC class III region near the junction with the class II: gene for receptor of advanced glycosylation end products, PBX2 homeobox gene and a notch homolog, human counterpart of mouse mammary tumor gene int-3 Genomics 23 1994 408 419
13. H. Yonekura, Y. Yamamoto, S. Sakurai, R.G. Petrova, M.J. Abedin, H. Li, K. Yasui, M. Takeuchi, Z. Makita, S. Takasawa, H. Okamoto, T. Watanabe, and H. Yamamoto Novel splice variants of the receptor for advanced glycation end-products expressed in human vascular endothelial cells and pericytes, and their putative roles in diabetes-induced vascular injury Biochem. J. 370 2003 1097 1109
14. B.I. Hudson, M.H. Stickland, and P.J. Grant Identification of polymorphisms in the receptor for advanced glycation end products (RAGE) gene: prevalence in type 2 diabetes and ethnic groups Diabetes 47 1998 1155 1157
15. B.I. Hudson, M.H. Stickland, T.S. Futers, and P.J. Grant Effects of novel polymorphisms in the RAGE gene on transcriptional regulation and their association with diabetic retinopathy Diabetes 50 2001 1505 1511
16. B.I. Hudson, M.H. Stickland, T.S. Futers, and P.J. Grant Study of the -429T/C and -374T/A receptor for advanced glycation end products promoter polymorphisms in diabetic and nondiabetic subjects with macrovascular disease Diabetes Care 24 2001 2004
17. M.G. Petrovic, K. Steblovnik, B. Peterlin, and D. Petrovic The -429T/C and -374T/A gene polymorphisms of the receptor of advanced glycation end products gene are not risk factors for diabetic retinopathy in Caucasians with type 2 diabetes Klin. Monatsbl. Augenheilkd 220 2003 873 876
18. X. JiXiong, X. BiLin, Y. MingGong, and L. ShuQin -429T/C and -374T/A polymorphisms of RAGE gene promoter are not associated with diabetic retinopathy in Chinese patients with type 2 diabetes Diabetes Care 26 2003 2696 2697
19. K. Pettersson-Fernholm, C. Forsblom, B.I. Hudson, M. Perola, and P.J. Grant Groop Per-Henrik, for the FinnDiane Study Group, The functional -374T/A RAGE gene polymorphism is associated with proteinuria and cardiovascular disease in type 1 diabetic patients Diabetes 52 2003 891 894
20. G. Rudofsky Jr., B. Isermann, T. Schilling, S. Schiekofer, M. Andrassy, J.G. Schneider, M. Morcos, P.M. Humpert, A.A. Sayed, S. Witte, W. Renn, M. Pfohl, A. Hamann, V. Nosikov, E. Schleicher, H.U. Haring, G. Rudofsky, E. Ritz, P.P. Nawroth, and A. Bierhaus A 63 bp deletion in the promoter of RAGE correlates with a decreased risk for nephropathy in patients with type 2 diabetes Exp. Clin. Endocrinol. Diabetes 112 2004 135 141
21. American Diabetes Association, Report of the expert committee on the diagnosis and classification of diabetes mellitus, Diabetes Care 20 (1997) 20 1183-1197
22. Sixth Report of the Joint National Committee on Detection, Evaluation, and Treatment of High Blood Pressure, Arch. Intern. Med. 157 (1997) 2413-2445
23. G.A. Rose, H. Blackburn, R.F. Gillium, and R.J. Prineas Cardiovascular Survey Methods 1982 World Health Organization Geneva
24. M.O. Beck, S.P. Silveiro, R. Friedman, N. Clausell, and J.L. Gross Asymptomatic coronary artery disease is associated with cardiac autonomic neuropathy and diabetic nephropathy in type 2 diabetic patients Diabetes Care 22 1999 1745 1747
25. D.K. Lahiri, and J.I. Nurnberger A rapid non-enzymatic method for the preparation of HMW DNA from blood for RFLP studies Nucleic Acids Res. 19 1991 5444
26. J.H. Abramson, P.M. Gahlinger, Computer Programs for Epidemiologic Analyses: PEPI version 4.0. (2002) (Available from: 〈 http://www. sagebrushpress.com/pepibook.html 〉)
27. S. Schneider, D. Roessli, L. Excoffier, Arlequin ver. 2.001, A software for population genetics data analysis, (2000) (Available from: 〈 http://lgb.unige.ch/arlequin/ 〉)
28. R.C. Lewontin On measures of gametic disequilibrium Genetics 120 1988 849 852
29. C. Falcone, I. Campo, E. Emanuele, M.P. Buzzi, M. Zorzetto, I. Sbarsi, and M. Cuccia Relationship between the -374T/A RAGE gene polymorphism and angiographic coronary artery disease Int. J. Mol. Med. 14 2004 1061 1064