In vitro differentiation of mouse bone marrow mononuclear cells into hepatocyte-like cells

Hepatology Research

Volumn 31, Issue 4, 2005, Pages 223-231

  Shi, Xiao Lei ^a   Qiu, Yu Dong ^a   Wu, Xin Yu ^a   Xie, Ting ^a   Zhu, Zhang Hua ^a   Chen, Lei Lei ^a   Li, Lei ^a   Ding, Yi Tao ^a  

^a MEDICAL SCHOOL OF NANJING UNIVERSITY   (China)

Author keywords

Bone marrow mononuclear cell; Differentiation; Epidermal growth factor; Fibroblast growth factor 4; Hepatocyte; Hepatocyte growth factor; Oncostatin M

Indexed keywords

ALBUMIN; ALPHA FETOPROTEIN; CYTOKERATIN 18; FIBROBLAST GROWTH FACTOR 4; GLUCOSE 6 PHOSPHATASE; GLYCOGEN; HEPATOCYTE NUCLEAR FACTOR 3; MESSENGER RNA; ONCOSTATIN M; PREALBUMIN; SCATTER FACTOR; TYROSINE AMINOTRANSFERASE; UREA;

ANIMAL CELL; ARTICLE; BONE MARROW CELL; CELL COUNT; CELL CULTURE; CELL DIFFERENTIATION; CELL FUNCTION; CELL MEMBRANE; CELL METABOLISM; CELL STRUCTURE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CULTURE MEDIUM; CYTOPLASM; EPITHELIOID CELL; FLOW CYTOMETRY; GENE EXPRESSION; GLYCOGEN SYNTHESIS; IMMUNOFLUORESCENCE; IN VITRO STUDY; LIVER CELL; MONONUCLEAR CELL; MOUSE; NONHUMAN; PERIODIC ACID SCHIFF STAIN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TIME; UREA CYCLE; WESTERN BLOTTING;

EID: 19444384371     PISSN: 13866346     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.hepres.2005.01.011     Document Type: Article

References (37)

1. J.E. Everhart M. Lombardero K.M. Detre et al. Increased waiting time for liver transplantation results in higher mortality Transplantation 64 9 1997 1300-1306
2. S.C. Strom J.R. Chowdhury I.J. Fox Hepatocyte transplantation for the treatment of human disease Semin Liver Dis 19 1999 39-48
3. I.L. Weissman Stem cells: Units of development, units of regeneration, and units in evolution Cell 100 1 2000 157-168
4. G. Ferrari G. Cusella-De Angelis M. Coletta et al. Muscle regeneration by bone marrow-derived myogenic progenitors Science 279 1998 1528-1530
5. B.E. Petersen W.C. Bowen K.D. Patrene et al. Bone marrow as a potential source of hepatic oval cells Science 284 5417 1999 1168-1170
6. M.A. Eglitis E. Mezey Hematopoietic cells differentiate into both microglia and macroglia in the brains of adult mice Proc Natl Acad Sci USA 94 1997 4080-4085
7. E. Mezey K.J. Chandross G. Harta R.A. Maki S.R. Mckercher Turning blood into brain: Cells bearing neuronal antigens generated in vivo from bone marrow Science 290 2000 1779-1782
8. T. Brazelton F.M. Rossi G.I. Keshet H.M. Blau From marrow to brain: expression of neuronal phenotypes in adult mice Science 290 2000 1775-1779
9. N.D. Theise S. Badve R. Saxena et al. Derivation of hepatocytes from bone marrow cells in mice after radiation-induced myeloablation Hepatology 31 1 2000 235-240
10. M.R. Alison R. Poulsom R. Jeffery et al. Hepatocytes from non-hepatic adult stem cells Nature 406 6793 2000 257
11. N.D. Theise M. Nimmakayalu R. Gardner et al. Liver from bone marrow in humans Hepatology 32 1 2000 11-16
12. E. Lagasse H. Connors M. Al-Dhalimy et al. Purified hematopoietic stem cells can differentiate into hepatocytes in vivo Nat Med 6 11 2000 1229-1234
13. Y. Jiang B.N. Jahagirdar R.L. Reinhardt et al. Pluripotency of mesenchymal stem cells derived from adult marrow Nature 418 6893 2002 41-49
14. M.E. Hemler U. Rutishauser editors. Cell-to-cell contact and extracelluar matrix Curr Opin Cell Biol 12 5 2000 539-541
15. C. Birchmeier N. Rosenthal editors. Genes that control the development of migrating muscle precursor cells Curr Opin Cell Biol 12 6 2000 725-730
16. J.M. Wells D.A. Melton Vetebrate endoderm development Annu Rev Cell Dev Biol 15 1999 393-410
17. T. Taga T. Kishimoto Gp130 and the interleukin-6 family of cytokines Annu Rev Immunol 15 1997 797-819
18. Kamiya Akihide Kinoshita Taisei Miyajima Atsushi Oncostatin M and hepatocute growth factor induce hepatic maturation via distinct signaling pathways FEBS Lett 492 2001 90-94
19. G.K. Michalopeulos M.C. DeFrances Liver regeneration Science 276 5309 1997 60-66
20. M. Levite A. Meshorer Y. Reisner A rapid method for obtaining murine bone marrow cells in high yield Bone Marrow Transplant 8 3 1991 225-227
21. P.O. Seglen Preparation of isolated rat liver cells Methods Cell Biol 13 1976 23-28
22. C.J. Pan K.J. Lei H. Chen J.M. Ward J.Y. Chou Ontogeny of the murine glucose-6-phosphatase system Arch Biochem Biophys 358 1 1998 17-24
23. A. Makover D.R. Soprano M.L. Wyatt D.S. Goodman An in situ-hybridization study of the localization of retinol-binding protein and transthyretin messenger RNAs during fetal development in the rat Differentiation 40 1 1989 17-25
24. L.L. Shelly W. Tynan W. Schmid G. Schutz G.C. Yeoh Hepatocyte differentiation in vitro: Initiation of tyrosine amino transferase expression in cultured fetal rat hepatocytes J Cell Biol 109 1989 3403-3410
25. J.Y. Chou Regulators of fetal liver differentiation in vitro Arch Biochem Biophys 263 2 1988 378-386
26. A.J. Becker E.A. McCullough J.E. Till Cytological demonstration of the clonal nature of spleencolonies derived from transplanted mouse marrow cells Nature 197 1963 452-454
27. M. Owen Marrows from stromal stem cells J Cell Science Suppl 10 1988 63-76
28. Wang PP, Wang JH, Ya ZP, et al. Expression of hepatocyte-like phenotypes in bone marrow stromal cells after HGF induction. Biochem Biophys Res Commun 2004;320(3):712-6.
29. Verfaillie CM, Pera MF, Lansdorp PM. Stem cells: Hype and reality. Hematology 2002;1:369-91.
30. S.N. Bhatia U.J. Balis M.L. Yarmush M. Toner Effect of cell-cell interactions in preservation of cellular phenotype: Cocultivation of hepatocytes and nonparenchymal cells FASEB J 13 14 1999 1883-1900
31. K.S. Zaret Liver specification and early morphogenesis Mech Dev 92 1 2000 83-88
32. K.S. Zaret Hepatocyte differentiation: From the endoderm and beyond Curr Opin Genet Dev 11 5 2001 568-574
33. H. Kawada M. Ogawa Bone marrow origin of hematopoietic progenitors and stem cells in murine muscle Blood 98 7 2001 2008-2013
34. WM. Rideout 3rd T. Wakayama A. Wutz et al. Generation of mice from wild type and targeted ES cells by nuclear cloning Nat Genet 24 2 2000 109-110
35. I. Wilmut A.E. Schnieke J. Mcwhir et al. Viable offspring derived from fetal and adult mammalian cells Nature 385 6619 1997 810-813
36. N. Terada T. Hamazaki M. Oka et al. Bone marrow cells adopt the phenotype of other cells by spontaneous cell fusion Nature 416 6880 2002 542-545
37. Q.Y. Ying J. Nichols E.P. Evans et al. Changing potency by spontaneous fusion Nature 416 6880 2002 545-548